We argue that David Lewis’s principal principle implies a version of the principle of indifference. The same is true for similar principles that need to appeal to the concept of admissibility. Such principles are thus in accord with objective Bayesianism, but in tension with subjective Bayesianism. 1 The Argument2 Some Objections Met.

The mechanistic and causal accounts of explanation are often conflated to yield a ‘causal-mechanical’ account. This paper prizes them apart and asks: if the mechanistic account is correct, how can causal explanations be explanatory? The answer to this question varies according to how causality itself is understood. It is argued that difference-making, mechanistic, dualist and inferentialist accounts of causality all struggle to yield explanatory causal explanations, but that an epistemic account of causality is more promising in this regard.

Machamer, Darden and Craver: ‘Mechanisms are entities and activities organized such that they are productive of regular changes from start or set-up to finish or termination conditions.’ (Machamer, Darden and Craver 2000 p3.) Glennan: ‘A mechanism for a behavior is a complex system that produces that behavior by the interaction of a number of parts, where the interactions between parts can be characterized by direct, invariant, change-relating generalizations.’ (Glennan 2002b pS344.) Bechtel and Abrahamsen: ‘A mechanism is a structure performing a (...) function in virtue of its component parts, component operations, and their organization. The orchestrated functioning of the mechanism is responsible for one or more phenomena.’ (Bechtel and Abrahamsen 2005 p423.). (shrink)

When a proposition is established, it can be taken as evidence for other propositions. Can the Bayesian theory of rational belief and action provide an account of establishing? I argue that it can, but only if the Bayesian is willing to endorse objective constraints on both probabilities and utilities, and willing to deny that it is rationally permissible to defer wholesale to expert opinion. I develop a new account of deference that accommodates this latter requirement.

As demonstrated repeatedly in the press, unethical decisions lead to damaged reputations and financial loss in business. This practical briefing provides board members and executives with advice on handling key business areas where ethics are essential.

In this chapter we explore the process of extrapolating causal claims from model organisms to humans in pharmacology. We describe and compare four strategies of extrapolation: enumerative induction, comparative process tracing, phylogenetic reasoning, and robustness reasoning. We argue that evidence of mechanisms plays a crucial role in several strategies for extrapolation and in the underlying logic of extrapolation: the more directly a strategy establishes mechanistic similarities between a model and humans, the more reliable the extrapolation. We present case studies from (...) the research on atherosclerosis and the development of statins, that illustrate these strategies and the role of mechanistic evidence in extrapolation. (shrink)

Objective Bayesianism has been criticised for not allowing learning from experience: it is claimed that an agent must give degree of belief ½ to the next raven being black, however many other black ravens have been observed. I argue that this objection can be overcome by appealing to objective Bayesian nets, a formalism for representing objective Bayesian degrees of belief. Under this account, previous observations exert an inductive influence on the next observation. I show how this approach can be used (...) to capture the Johnson-Carnap continuum of inductive methods, as well as the Nix-Paris continuum, and show how inductive influence can be measured. (shrink)

The publication of Political Liberalismhas allowed John Rawls to bring to the fore issues that remained in the background of A Theory of Justice. His explicit attention to the concept of ‘the reasonable’ is a welcome development. In a more recent publication, he affirms the importance of this concept, ‘while [granting] that the idea of the reasonable needs a more thorough examination than Political Liberalism offers.’ In this paper, I will present a critical exposition of the senses of the reasonable (...) on which justice as fairness relies. Rawls employs the term in four main contexts. I will outline these various senses and argue that in each case, a controversy in the secondary literature can be resolved by close attention to the concept of the reasonable. In three of these contexts, Rawls relies on what I will call a ‘strong’ sense of the reasonable, while in one he sometimes seems to rely on a ‘weak’ sense. I argue that justice as fairness is best served by relying on a strong sense throughout. (shrink)

The paper treats Avicenna’s ’metaphysical’ argument for the existence of God and the modal metaphysics that underpins it. Earlier analyses of modalities attempted to reduce necessity, possibility and impossibility to nonmodal elements, which was done most commonly by appealing to a temporal frequency model of modalities. In contrast, Avicenna believed that modalities were an inherent feature of existence, and so just as there is nothing more basic than existence, so likewise there is nothing more basic in term of which modalities (...) can be explained. The article concludes by considering how Avicenna’s modal metaphysics in turn provides him the means to show the absolute and nonconditional necessity of God, as opposed to the conditional necessity of earlier ’physical’ arguments. (shrink)

The prospect of human genetic enhancement requires an institutional response, and probably the creation of new institutions. The governance of genetic enhancement technologies, moreover, needs to be global in scope. In this article, I analyze the debate on the global governance of human genetic enhancement. I begin by offering a philosophical justification for the need to adopt a global framework for governance of technologies that would facilitate the improvement of non-pathological genetic traits. I then summarize the main concrete proposals that (...) have recently emerged to govern genome editing at the global level. Finally, I develop some impediments that limit the impetus for global governance of genetic enhancement. (shrink)

It is generally recognized that emotional states induce impatience, in the sense of a heightened preference for early rewards over later rewards. In this article I argue that they also induce urgency, in the sense of a preference for early action over later action. I adduce scattered evidence for the existence of the phenomenon and sketch a possible experiment that might demonstrate it, while also noting that it may be hard to distinguish urgency-based action from action based on the anticipation (...) of the decay of emotion. (shrink)

This chapter addresses two questions: what are causal relationships? how can one discover causal relationships? I provide a survey of the principal answers given to these questions, followed by an introduction to my own view, epistemic causality, and then a comparison of epistemic causality with accounts provided by Judea Pearl and Huw Price.

Discussion of the role which religious experience can play in warranting theistic belief has received a great deal of attention within contemporary philosophy of religion. By contrast, the relationship between experience and atheistic belief has received relatively little focus. Our aim in this paper is to begin to remedy that neglect. In particular, we focus on the hitherto under-discussed question of whether experiences of God’s absence can provide positive epistemic status for a belief in God’s nonexistence. We argue that there (...) is good reason to accept an epistemic parity between experiences of God’s presence and experiences of God’s absence. (shrink)

Aristotle's account of place in terms of an innermost limit of a containing body was to generate serious discussion and controvery among Aristotle's later commentators, especially when it was applied to the cosmos as a whole. The problem was that since there is nothing outside of the cosmos that could contain it, the cosmos apparently could not have a place according to Aristotle's definition; however, if the cosmos does not have a place, then it is not clear that it could (...) move, but it was thought to move, namely, in its daily revolution, which was viewed as a kind of natural locomotion and so required the cosmos to have a place. The study briefly outlines Aristotle's account of place and then considers its fate, particularly with respect to the cosmos and its motion, at the hands of later commentators. To this end, it begins with Theophrastus' puzzles concerning Aristotle's account of place, and how later Greek commentators, such as Alexander of Aphrodisias, Themistius and others, attempted to address these problems in what can only be described as ad hoc ways. It then considers Philoponus' exploitation of these problems as a means to replace Aristotle's account of place with his own account of place understood in terms of extension. The study concludes with the Arabic Neoplatonizing Aristotelian Avicenna and his novel introduction of a new category of motion, namely, motion in the category of position. Briefly, Avicenna denies that the cosmos has a place, and so claims that it moves not with respect to place, but with respect to position. (shrink)

The need for a coherent answer to this question has become increasingly urgent in the past few years, particularly in the field of artificial intelligence. There, both logical and probabilistic techniques are routinely applied in an attempt to solve complex problems such as parsing natural language and determining the way proteins fold. The hope is that some combination of logic and probability will produce better solutions. After all, both natural language and protein molecules have some structure that admits logical representation (...) and reasoning; yet inherent uncertainties also demand the use of probabilistic methods: this structure is only partially known and does not in any case fully determine a solution—context or environment also play a role. (shrink)

Journals are failing in their obligation to ensure that research is fairly represented to their readers, and must act decisively to retract fraudulent publications. Recent case reports have exposed how marketing objectives usurped scientific testing and compromised the credibility of academic medicine. But scant attention has been given to the role that journals play in this process, especially when evidence of research fraud fails to elicit corrective measures. Our experience with The Journal of the American Academy of Child and Adolescent (...) Psychiatry (JAACAP) illustrates the nature of the problem. The now-infamous Study 329 of paroxetine in adolescent depression was negative for efficacy on all eight protocol-specified outcomes and positive for harm, but JAACAP published a report of this study that concluded that “paroxetine is generally well tolerated and effective for major depression in adolescents.” The journal’s editors not only failed to exercise critical judgment in accepting the paper, but when shown evidence that the paper misrepresented the science, refused either to convey this information to the medical community or to retract the article. (shrink)

High atop cascading waterfalls and deep within the lush green depths of the valleys, Swiss photographer Ruedi Homberger has for more than twenty years captured in photographs the majestic beauty of eastern Alaska's Wrangell Mountain range. In addition to summiting some of the Wrangells' loftiest peaks, Homberger has in recent years incorporated a technically challenging new approach into his work. Flying above the mountains in a small plane, Homberger literally goes to new heights to reveal a series of stunning aerial (...) views. The first book-length collection of photographs focusing exclusively on the Wrangell-Saint Elias National Park and Preserve, My Wrangell Mountains offers readers a rare opportunity to “stand among the giants.” Included in this magnificent oversized volume are nearly three hundred full-color photographs and an accompanying selection of sketches by award-winning illustrator Jon Van Zyle. (shrink)

¿Puede la inteligencia artificial (IA) hacernos más morales o ayudarnos a tomar decisiones más éticas? El libro Más (que) humanos. Biotecnología, inteligencia artificial y ética de la mejora, editado por Francisco Lara y Julian Savulescu (2021), puede inspirarnos filosóficamente sobre este debate contemporáneo. En esta nota crítica, contextualizo la aportación general del volumen y analizo los dos últimos capítulos de Monasterio-Astobiza y de Lara y Deckers, quienes argumentan a favor del uso de la IA para hacernos mejores agentes morales. El (...) objetivo es ampliar y matizar críticamente algunas cuestiones clave sobre cómo la IA puede asistirnos para tomar decisiones más éticas. (shrink)

Norman Geras argues for the incorporation of elements from the just war tradition into the ethics of social change. But this does not go far enough. In this paper I argue for a prefigurative constraint: that action intended to bring about social transformation ought to prefigure that transformation, and bear those properties of the future state of affairs that make the future state of affairs morally valuable. I defend the idea of a prefigurative constraint against some objections and introduce a (...) schema to relate political action to morally valuable end states. (shrink)

Rawls defended the model of a property‐owning democracy; critically reflected on the US constitutional history of free speech; and argued that “both Hiroshima and the fire‐bombing of Japanese cities were great evils.” What ties these and many other disparate concerns together is the idea of the original position. “Justice as Fairness,” published in 1958, included several crucial developments. Rawls proposes his “two principles of justice,” which, through various revisions, he would defend for the rest of his career: a principle of (...) equal liberty and a principle encompassing fair equality of opportunity and the difference principle. Rawls argues that parties would accept his two principles in two stages: first, by a comparison with average utilitarianism, which focuses on his first principle, and then by a comparison with so‐called “mixed conceptions,” which focuses on the second principle. Rawls continues to claim that the original position establishes a form of objectivity. (shrink)

In this chapter, I defend the thesis that all social phenomena—their structure and their change—are in principle explicable in ways that only involve individuals—their properties, their goals, their beliefs, and their actions. Such explanations are sometimes unfeasible for practical reasons, but it is argued that they should always define the goal of scholars. In addition to considering the views of Tocqueville, Marx, and Durkheim, the chapter addresses the views of G. A. Cohen, Pierre Bourdieu, Robert Putnam, and Kenneth Arrow.