Microbes in the gastrointestinal tract are under selective pressure to manipulate host eating behavior to increase their fitness, sometimes at the expense of host fitness. Microbes may do this through two potential strategies: (i) generating cravings for foods that they specialize on or foods that suppress their competitors, or (ii) inducing dysphoria until we eat foods that enhance their fitness. We review several potential mechanisms for microbial control over eating behavior including microbial influence on reward and satiety pathways, production of (...) toxins that alter mood, changes to receptors including taste receptors, and hijacking of the vagus nerve, the neural axis between the gut and the brain. We also review the evidence for alternative explanations for cravings and unhealthy eating behavior. Because microbiota are easily manipulatable by prebiotics, probiotics, antibiotics, fecal transplants, and dietary changes, altering our microbiota offers a tractable approach to otherwise intractable problems of obesity and unhealthy eating. (shrink)

Is there a world beyond the senses? Can we perceive future events before they occur? Is it possible to communicate with others without need of our complex sensory-perceptual apparatus that has evolved over hundreds of millions of years? Can our minds/souls/personalities leave our bodies and operate with all the knowledge and information-processing ability that is normally dependent upon the physical brain? Do our personalities survive physical death?

_ Source: _Page Count 27 This is an explication and defense of P. F. Strawson’s naturalist theory of free will and moral responsibility. I respond to a set of criticisms of the view by free will skeptics, compatibilists, and libertarians who adopt the _core assumption_: Strawson thinks that our reactive attitudes provide the basis for a rational justification of our blaming and praising practices. My primary aim is to explain and defend Strawson’s naturalism in light of criticisms based on the (...) core assumption. Strawson’s critiques of incompatibilism and free will skepticism are not intended to provide rational justifications for either compatibilism or the claim that some persons have free will. Hence, the charge that Strawson’s “arguments” are faulty is misplaced. The core assumption resting behind such critiques is mistaken. (shrink)

"He completed the assignment in two phases: The photographs made during the first phase capture the natural ruggedness of the terrain and establish its relationship to the developed neighboring enclaves. Those made during the second phase not only record the actual construction process but also reveal Deal's personal perspective on the qualities of light and the creation of form. Represented in this book as a selection from the resulting portfolio, Topos, a Greek word meaning place, site, position, and occasion - (...) Deal's artistic legacy to the Gerry Center."--BOOK JACKET. (shrink)

Lacan, qui a prôné le "retour à Freud", qui s'est donc voulu le défenseur strict de la cause freudienne, ne s'est jamais réclamé que de la psychanalyse. Il a cependant beaucoup fréquenté les philosophes : non seulement Hegel à travers la lecture de Kojève, mais aussi et surtout Bataille et Heidegger, deux auteurs dont il a été, on le sait aujourd'hui, intellectuellement très proche. Cette profonde influence sur son oeuvre pose alors la question de savoir s'il serait possible de proposer (...) une interprétation philosophique de celle-ci. Pourrait-t-on développer une philosophie lacanienne? Ce livre s'efforce de montrer qu'une telle lecture de la pensée lacanienne est non seulement concevable, mais que la possibilité en a été indiquée par Lacan lui-même, en particulier dans le Séminaire VII, bien qu'il ne s'y soit jamais engagé pleinement. Il apparaîtra alors qu'une telle interprétation de Lacan, qui va au-delà de la lettre de sa pensée mais ne la trahit pas et qui est même autorisée par la richesse et la complexité de l'oeuvre, ouvre non seulement des perspectives nouvelles sur celle-ci, mais subvertit totalement les présupposés qui portent la philosophie traditionnelle depuis ses origines. Que pourrait être, finalement, le lacanisme en philosophie? Telle est donc la question à laquelle cet essai tente de répondre. (shrink)

Accountability means accepting responsibility for your actions and repairing any harm you have done. This workbook can be used by anyone who is ready to do the work to change toxic behaviors and patterns, from quitting smoking to atoning for abuse or crimes. At its heart, accountability is understanding that your actions do not always have the impact that you intend. Sometimes this is as simple as getting to know yourself and apologizing. Sometimes it's a years-long process to recognize the (...) motivations and behaviors that you see inside yourself and feel like you have no control over. Ultimately, accountability is something we each must choose for ourselves; nobody else can do it for us. The results can be unexpected and transformative, and improve your friendships, relationships, work, and community; most of all it's about coming to peace with yourself. The authors share tough lessons learned through many years of personal and professional experience. This workbook will walk you through your own head to understand your own patterns and behaviors, untangle them, and live the kind of life you want. (shrink)

Margaret Gilbert has argued that an agreement is not exchange of promises, since no such exchange plays all the roles she claims are distinctive of agreements. After briefly discussing the notion of intention and the principles governing intentions, I argue that a certain type of exchange of intentions — in which one person forms a conditional intention to act if the other does, and the other forms an unconditional intention to act on the presumption that the first will do what (...) they have said — plays all these roles, and so conclude that an agreement is in fact an exchange of intentions. (shrink)

Many philosophers contend that selfhood involves a uniquely first-personal experiential dimension, which precedes any form of socially dependent selfhood. In this paper, I do not wish to deny the notion of such a “minimal” experiential dimension as encapsulating the very givenness of experience as for a certain subject, such that experiences are accessible to this subject in a way that they are not for others. However, I do wish to deny any temptation to view minimal experiential selfhood as ontogenetically more (...) primitive than socially constituted selfhood. That is, the ‘thinnest’ construal of minimal experiential selfhood fails to properly account for characteristics that are essential to human selfhood; namely, the intimate, embodied interactions that unfold at the incipient moments of human life. I argue that taking the ontogenesis of embodied human existence seriously involves accepting the de facto equiprimordiality of minimal experientialiasm with a ‘minimal’ form of relational selfhood, i.e. the co-constitution of experience through engagements with others. (shrink)

In Unifying Biology, Smocovitis offers a series of claimsregarding the relationship between key actors in the synthesisperiod of evolutionary studies and positivism, especially claimsentailing Joseph Henry Woodger and the Unity of Science Movement.This commentary examines Woodger''s possible relevance to key synthesis actors and challenges Smocovitis'' arguments for theexplanatory relevance of logical positivism, and positivism moregenerally, to synthesis history. Under scrutiny, these arguments areshort on evidence and subject to substantial conceptual confusion.Though plausible, Smocovitis'' minimal interpretation – that somegeneralised form of Comtean (...) positivism had a role in synthesishistory – requires more of an evidential basis and must engageexisting scholarship on epistemic reforms in the biological sciencesprior to the synthesis period. Smocovitis is right to investigateepistemology in the synthesis period of evolutionary studies and tolook for links to wider changes in science and philosophy. However,in its present form, Unifying Biology fails to support herbasic interpretation. (shrink)

The Quest for Learning: How to Maximize Student Engagement affirms that traditional classroom learning experiences, in which you plan lessons and voice instruction at the front of the room, do not meet 21st century students learning needs. Questing is a customizable pedagogy that readers and their students together tailor to a students abilities, needs, and interests. Side by side, and aligned with learning targets, readers learn how teachers and students determine what a student will learn about and at what pace. (...) Authors Marie Alcock, Michael Fisher, and Allison Zmuda propose three tenets of engagement (1) the learner engages with relevant, worthy inquiries and experiences that are interesting or emotionally gripping, (2) the learner engages in an active, intentional cycle with clear goals and right-sized, actionable steps, and (3) the learner engages in social, collaborative opportunities that grow expertise that allow students to take ownership of their learning. To further that ownership, students decide which design type they want to use to explore their quest topic (1) question, (2) game, or (3) network. Students then pursue lines of inquiry, design or play games, or communicate with peers and experts in online and physical spaces. Each is a method for becoming an expert on chosen topics. (shrink)

The Kansas-Nebraska Act of 1854 officially opened the Great Plains to westward settlement, and the public survey of 1855 by Charles A. Manners and Joseph Ledlie along the Sixth Principal Meridian established the grid by which the uncharted expanse of the Great Plains was brought into scale. The mechanical act performed by land surveyors is believed by photographer Joe Deal to be powerfully similar to the artistic act of making a photograph.To Deal, both acts are about establishing a frame around (...) a vast scene that suggests no definite boundaries of its own. Thus, when approaching his own photographs of the Great Plains, Deal viewed his photography as a form of reenactment, a method of understanding how it felt to contain the Great Plains in smaller, more measurable units. In West and West, Deal, who was born and raised in Kansas, revisited the Kansas-Nebraska territory and applied his photographic understanding of the landscape grid and horizon line to illuminate the sense of infinite space that transcends the reality of the survey. As Deal writes in his concluding essay: “If the square, as employed in the surveys of public lands, could function like a telescope, framing smaller and smaller sections of the plains down to a transect, it can also be used as a window, equilaterally divided by the horizon, that begins with a finite section of the earth and sky and restores them in the imagination to the vastness that now exists as an idea: the landscape that is contained within the perfect symmetry of the square implies infinity.” The stunning photographs in West and West present the Great Plains from a rare perspective. From this vantage point, Deal is able to distill and contemplate its expanse. (shrink)

Harmonic Grammar (HG) and Optimality Theory (OT) are closely related formal frameworks for the study of language. In both, the structure of a given language is determined by the relative strengths of a set of constraints. They differ in how these strengths are represented: as numerical weights (HG) or as ranks (OT). Weighted constraints have advantages for the construction of accounts of language learning and other cognitive processes, partly because they allow for the adaptation of connectionist and statistical models. HG (...) has been little studied in generative linguistics, however, largely due to influential claims that weighted constraints make incorrect predictions about the typology of natural languages, predictions that are not shared by the more popular OT. This paper makes the case that HG is in fact a promising framework for typological research, and reviews and extends the existing arguments for weighted over ranked constraints. (shrink)

Religion is an important element of end-of-life care on the paediatric intensive care unit with religious belief providing support for many families and for some staff. However, religious claims used by families to challenge cessation of aggressive therapies considered futile and burdensome by a wide range of medical and lay people can cause considerable problems and be very difficult to resolve. While it is vital to support families in such difficult times, we are increasingly concerned that deeply held belief in (...) religion can lead to children being potentially subjected to burdensome care in expectation of ‘miraculous’ intervention. We reviewed cases involving end-of-life decisions over a 3-year period. In 186 of 203 cases in which withdrawal or limitation of invasive therapy was recommended, agreement was achieved. However, in the 17 remaining cases extended discussions with medical teams and local support mechanisms did not lead to resolution. Of these cases, 11 (65%) involved explicit religious claims that intensive care should not be stopped due to expectation of divine intervention and complete cure together with conviction that overly pessimistic medical predictions were wrong. The distribution of the religions included Protestant, Muslim, Jewish and Roman Catholic groups. Five of the 11 cases were resolved after meeting religious community leaders; one child had intensive care withdrawn following a High Court order, and in the remaining five, all Christian, no resolution was possible due to expressed expectations that a ‘miracle’ would happen. (shrink)

Since the days of the Ancient Greeks, history has been perceived as the academic study of the past. Unfortunately, it has generally been taught as a litany of rigid, boring facts intended to be accepted rather than questioned. This has been reinforced for decades by weighty textbooks that overwhelm the reader with mind-numbing details presented in a chronological sequence. The end result is that students see little relevance of what they learn in history class to the real world, and many (...) simply struggle to stay awake. Compared to other subjects taught at the secondary level, history is frequently judged to be the most boring. This is largely because it is viewed as an intellectually lifeless subject that presents few opportunities for active engagement. (shrink)

The answer is surprising, and what we're about to learn will wake us up to a reality most of us never knew existed.The reason we're so oblivious is because we've all been operating at human speed, relying on our own physical power and our five senses. But there is something extremely important we've all been missing. It holds the key to everything good--the key to life, success, happiness, peace of mind, and understanding beyond our wildest imagination. It's perhaps the best-kept (...) secret in the history of mankind and it packs a staggering, invigorating message that can change your life for the better--improving understanding, eliminating anxiety, and helping to extend your living years indefinitely. All we have to do is open our eyes and ears.We're all inundated with this secret at all times. It's present in our favorite songs and movies, the stories we tell our children, and even in every commercial campaign! The secret is broadcast in famous news stories including the coronavirus pandemic, the sinking of the Titanic, or the collapse of the World Trade Center on 9/11. It's in ordinary life activities such as breathing, sleeping, waking up, traveling, sex, and getting married and changing one's name.Now, bestselling author and award-winning journalist Joe Kovacs reveals the solution--cracking the divine code that shifts our minds from operating at slow, human speed and making the jump to the incredibly quick "God speed."Hundreds of ancient mysteries and prophecies are instantly unsealed as the master key that unlocks the mystery of everything is now in your hands. (shrink)

By pairing translations of _Gorgias_ and _Rhetoric_, along with an outstanding introductory essay, Joe Sachs demonstrates Aristotles response to Plato. If in the _Gorgias_ Plato probes the question of what is problematic in rhetoric, in _Rhetoric_, Aristotle continues the thread by looking at what makes rhetoric useful. By juxtaposing the two texts, an interesting "conversation" is illuminated—one which students of philosophy and rhetoric will find key in their analytical pursuits. Focus Philosophical Library translations are close to and are non-interpretative of (...) the original text, with the notes and a glossary intending to provide the reader with some sense of the terms and the concepts as they were understood by Aristotle and Plato’s immediate audience. (shrink)

There are many cases in which, by making some great sacrifice, you could bring about either a good outcome or a very good outcome. In some of these cases, it seems wrong for you to bring about the good outcome, since you could bring about the very good outcome with no additional sacrifice. It also seems permissible for you not to make the sacrifice, and bring about neither outcome. But together, these claims seem to imply that you ought to bring (...) about neither outcome rather than the good outcome. And that seems very counterintuitive. In this paper, I develop this problem, propose a solution, and then draw out some implications both for how we should understand supererogation and for how we should approach charitable giving. (shrink)

This collection assembles Church's referee reports, Fitch's 1963 paper, and nineteen new papers on the knowability paradox.

Is there any number of people you should save from paralysis rather than saving one person from death? Is there any number of people you should save from a headache rather than saving one person from death? Many people answer ‘yes’ and ‘no’, respectively. They therefore accept a partially aggregative moral view. Patrick Tomlin has recently argued that the most promising partially aggregative views in the literature have implausible implications in certain cases in which there are additions or subtractions to (...) the groups of people that we can save. Several philosophers have begun responding to this argument by developing partially aggregative views that avoid the relevant implications. In this paper, I extend Tomlin’s argument to create a dilemma that no partially aggregative view can avoid. I conclude that we should accept a fully aggregative moral view. (shrink)

Our ability to survive in a world beset by looming global perils depends ultimately on our collective will to harness our intellects and change our behaviors. In order to respond appropriately, people must first believe that serious problems exist, that there are potential solutions, and that they have a role to play in finding and implementing them. Without such beliefs, individual change is unlikely. In order to promote belief change, it is important to understand how beliefs are learned, what their (...) functions are, and why they are so often resistant to change. These issues are discussed in this article, along with the role that social dilemmas play in inhibiting individually prosocial behavior. (shrink)