Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

_Reconsiders the contemporary relevance of Schelling’s radical philosophical and religious ecology._.

"As the child of refugees of World War II Europe and a renowned philosopher and scholar of propaganda, Jason Stanley has a deep understanding of how democratic societies can be vulnerable to fascism: Nations don't have to be fascist to suffer from fascist politics. In fact, fascism's roots have been present in the United States for more than a century. Alarmed by the pervasive rise of fascist tactics both at home and around the globe, Stanley focuses here on the (...) structures that unite them, laying out and analyzing the ten pillars of fascist politics--the language and beliefs that separate people into an 'us' and a 'them.' He knits together reflections on history, philosophy, sociology, and critical race theory with stories from contemporary Hungary, Poland, India, Myanmar, and the United States, among other nations. He makes clear the immense danger of underestimating the cumulative power of these tactics, which include exploiting a mythic version of a nation's past; propaganda that twists the language of democratic ideals against themselves; anti-intellectualism directed against universities and experts; law and order politics predicated on the assumption that members of minority groups are criminals; and fierce attacks on labor groups and welfare. These mechanisms all build on one another, creating and reinforcing divisions and shaping a society vulnerable to the appeals of authoritarian leadership. By uncovering disturbing patterns that are as prevalent today as ever, Stanley reveals that the stuff of politics--charged by rhetoric and myth--can quickly become policy and reality. Only by recognizing fascists politics, he argues, may we resist its most harmful effects and return to democratic ideals."--Jacket. (shrink)

Puts Schelling in conversation with twentieth-century continental philosophy.

These 14 essays bring Schelling in tune with such luminaries as Heidegger, Derrida, Bataille, Foucault, Deleuze, Levinas, and Irigaray and situate him squarely in the centre of current themes.

This chapter considers Nietzsche's and Spinoza's views on freedom – a theme of central interest to both thinkers. It draws from Yonover in order to provide an outline of their rejections of one conception of freedom: freedom of the will. The chapter also considers their positive visions of a very different kind of freedom, which rather consists in self‐determination. Nietzsche's naturalism surely plays a major role in his rejection of freedom of the will, too. Nietzsche and Spinoza praise a comparable (...) kind of freedom characterized especially by the primary elements. Spinoza writes in the first appendix of the Ethics that at least one portion of the foremost “prejudice” to undermine is the idea that God “directs all things to some certain end”. (shrink)

_A new English translation of Schelling’s unfinished magnum opus, complete with a contextualizing introduction by the translator._.

Essays exploring a rich intersection between phenomenology and idealism with contemporary relevance.

Some feminists and animal advocates defend what I call the Linked Oppressions Thesis, according to which the oppression of women and the oppression of animals are linked causally, materially, normatively, and/or conceptually. Alasdair Cochrane offers objections to several versions of the Linked Oppressions Thesis and concludes that the Thesis should be rejected in all its forms. In this paper I defend the Thesis against Cochrane's objections as well as objections leveled by Beth Dixon, and argue that the failure of these (...) objections illuminates the idea of linked oppressions as well as misunderstandings of the Linked Oppressions Thesis, and may provide guidance to philosophers theorizing animal rights from a feminist perspective. (shrink)

The significance of educational research is today predicated on its ability to engage with the ecological, economic, and political challenges of the anthropocene, for where we might take seriously education’s commitment to the future necessitates a sustained encounter with the implications and questions raised in the wake of ‘our’ mutated planetary ecology. To repeat in the image of those educational practices, models and patterns of thinking that have contributed to the contemporary ecological crisis of the planet falls gravely short of (...) apprehending what it might entail to live in the contemporary moment. Yet further, where education is intimate to teleology, it is today clear that the image of the future posited educationally has fallen out of synch with the ‘outside thought’ of ecocatastrophe, or rather, our being ‘thought’ from the inhuman perspective of a planet destined to go on without us. Educationally, this threat poses a quite remarkable opportunity, for where human thought might be doomed to extinction, the question of how and where we might think assumes urgency. In this vein, this essay explores the wisdom that ‘we’ are and will be thought from perspectives alien to human desire becomes a catalyst for how educational research might be rethought otherwise in a more-than-human world. (shrink)

Most people seem to believe that it is wrong to cause needless suffering and death to non-human animals, and yet most people also contribute to the needless suffering and death of a great many animals. If speciesism is understood as a psychological prejudice—the tendency of an individual human agent to disregard the interests of animals—then this fact is extremely difficult to explain. I argue that once speciesism is understood structurally—as a matter of injustice rather than a matter of interpersonal wrongdoing (...) or individual prejudice—the project of explaining how so many humans are implicated in animal suffering becomes much more tractable. Drawing on the work of feminist theorists such as Sally Haslanger and Catharine MacKinnon, I suggest a way of reconceiving the question of the moral status of animals as a political question about the construction of animals and animality through our social, cultural, legal, and linguistic practices. (shrink)

Teaching healthcare ethics at the doctoral level presents a particular challenge. Ethics is often taught to medical students, but rarely is medicine taught to graduate students in health care ethics. In this paper, Medicine for Ethicists [MfE] — a course taught both didactically and experientially — is described. Eight former MfE students were independently interviewed in a semi-structured, open-ended format regarding their experience in the experiential component of the course. Themes included concrete elements about the course, elements related to the (...) broader PhD student learning experience, and themes related to the students’ past and future career experiences. Findings are related to the educational philosophy of John Dewey and David Kolb’s experiential learning theory. Broader implications of this work are explored. (shrink)

We systematically examined the content of the websites of 46 agencies that buy and sell human eggs to understand how they market themselves to both donors and recipients. We found that these websites use marketing techniques that obscure the realities of egg donation, presenting egg donation as a mutually beneficial and fulfilling experience. Sites emphasize egg donors' emotional fulfillment and address recipients' anxieties by stressing the ability to find the perfect “fit” or “match”, suiting recipients’“preferences”/“desires”, and even designing/customizing a child. (...) Agencies attempt to create a sense of connection between the recipients and donors by reporting donors' personal characteristics — e.g., interests/hobbies, traits, mood/temperament, and self-reported childhood behavior/memories. Sites present donors as caring/generous and smart/successful/beautiful. These data, the first to examine several key aspects of egg donation agency websites, reveal critical aspects of how these companies communicate to prospective donors and recipients, raising several ethical concerns. Websites frame information in ways that may bias consumers, making emotional appeals that may distract from appropriate risk/benefit assessments and obscure the ethical challenges of egg donation. These data highlight needs for improved practices, adherence to guidelines, and consideration of enhanced guidelines or policy. (shrink)

Schelling argued that early modern science had discarded the ancient teaching of matter – the world soul (die Weltseele or anima mundi, the unity of soul and body, eternity and time, absolute possibility and existence) – «into the common grave they dug for nature and have brought about the death of all science». In order to put science on a more philosophical tract, Schelling retrieved the work of Giordano Bruno as part of his «handful» of thinkers who in a contemporary (...) context appear on the border between an ancient but still vital sense of philosophy and the emerging scientific study of nature. (shrink)

Philosophy after comparative philosophy -- Thinking about Nietzsche and Zen -- Strange saints (Schopenhauer, Nietzsche, Hakuin) -- Convalescence (Nietzsche, James, Hakuin) -- Nietzsche in the pure land (Nietzsche, Shinran, Tanabe) -- Planomenal nourishment (Nietzsche, Deleuze, Dogen) -- Pure experience and philosophy after comparative philosophy.

Suppose all of the particles in the universe should happen to come to rest at the same time, in positions so arranged that all of the forces on every particle balance to zero at that time. What would happen next? Or rather, what does Newtonian mechanics say will happen next? Preface Inertia and Stasis 2.1 Stating the Law of Inertia more precisely 2.2 The stasis scenario Indeterministic Examples 3.1 Abstract example 3.2 Second example Non-Lipschitz Forces and Determinism Beyond the Stasis (...) Scenario CiteULike Connotea Del.icio.us What's this? (shrink)

This essay is devoted to an examination of the relationship between truth and laughter in the works of Nietzsche. My central text shall be the much malignedbook four of Zarathustra, with special attention paid to the braying of the ass. Laughter has been traditionally considered irrelevent to serious philosophical content and, at best, a stylistic quirk. I argue that this stems from a basic predjudice that is constitutive of a large part of the Western tradition, namely, the confusion of working (...) hard (a sine qua non for philosophy) with taking oneself seriously. I then analyze laughter in Nietzsche’s works as the voice of truth itself. Laughter is the affirmation of a register of truth as the other beginning that has been lost in every thing that begins. Such an analysis involves a discussion of the nature of both truth and laughter. In so doing, I also distinguish Nietzschean laughter from three representative and seminal accounts of laughter provided by Hobbes, Bergson, and Kant. (shrink)

This is the first of an ongoing series of review essays in which the authors of significant new works of philosophy engage their readers. These inaugural two readings discuss Rein Raud’s important new reassessment of contemporary ontology, Being in Flux: A Post-Anthropocentric Ontology of the Self. They consider its accomplishments, both on its own terms and with reference to its East Asian and South Asian precursors. Raud then offers a response.

This paper investigates the fragmentation required of the philosophy of history in light of three key moments in its formation: German Idealism’s desire to see freedom realized in the world, the death of God, and the disasters of the twentieth century. I argue that Walter Benjamin and Maurice Blanchot respond to these threads of the philosophy of history with revolutionary imperatives that belong to no program or project, imperatives that both reorganize and destructure the work of education, affirmations of transience (...) and unmediated violence. I argue, following their lead, that any philosophy of history today must begin in a refusal of state power and the mediated violence of contemporary forms of community. (shrink)

This paper aims to situate Agamben’s treatment of the issue of community. It shows how Agamben departs from and supplements the French discourse on community through a critique of negativity; how the significance of community is measured against the society of the spectacle; and how the alienation from our linguistic being, which the spectacle effects, conditions a politics opposed to the State apparatus. Agamben’s coming community appropriates the dispossession and impropriety of contemporary human being in order to reconfigure the relation (...) of belonging and singularity. (shrink)

In this essay I hope to make some new contributions to the philosophical opening occasioned by John Sallis’ articulation of an “elementology” more broadly and by his turn to Guo Xi’s exquisite Song Dynasty shan-shui scroll painting, Early Spring more particularly. I do so by bringing the remarkable writings by the American poet and thinker Gary Snyder, especially in relationship to his reading of the great Kamakura Zen Master Eihei Dōgen, directly into the fray of contemporary Continental discourses on the (...) elemental and the ecological. At the heart of this project is Snyder’s development of Dōgen’s elemental discourse of “mountains, rivers, and the great earth.” Like Sallis’ own efforts to recast language into a more elemental discourse, this essay will also focus on the manners of speaking specific to the philosophical and poetic self-presentation of the elements, including the relationship between the philosophical and the artistic as such. (shrink)

Inspirados en el poeta Romantico John Keats (1795-1821), en este artículo meditamos sobre lo que puede ocurrir en el espacio educativo si los docentes cultivan y alimentan el carácter poético y la capacidad negativa. El artículo busca retratar una disposición docente particular, y el impacto que esa disposición podría tener en la experiencia educativa de los docentes y sus estudiantes. Comenzando con algunas consideraciones sobre el carácter poético y la capacidad negativa, el artículo se propone ponderar cómo un docente con (...) carácter poético desafía la concepción familiar de la educación como una "búsqueda por la certeza" haciendo de la educación una travesía sin norte por las aguas de lo que no se sabe ni conoce. (shrink)

Several noted political theorists have argued that a state can be legitimate even if it does not generate in its citizens an obligation to obey the law. I argue that this claim is false. All plausible analyses of political legitimacy either build in the concept of political obligation, or else incorporate claims that require some account of political obligation. In either case, political legitimacy is possible only when a state successfully generates in its citizens an obligation to obey the law.

Hippiedom is the latest Cynic apparition. Both make fun of the rat race, money?making, accumulation, consumerism, uptightness, egodependence, Puritanism, racism, nationalism, sexism. Their rebellions transcend particular times and places and share a common target. Even the expressions of rebellion are largely the same, from long hair to panhandling to sexualizing in public. Of course there are differences. Thus the Cynics were not social dropouts, although remember hippie offshoots like the yippies. Nor did they go for artificially?induced highs and self?confidence, though (...) to them guts and freedom (as liberation, not primarily as option or responsibility) were the wildest things, man. (shrink)

Realizing a comprehensive approach to evidence-based practice in psychology requires the collaboration of academic researchers and practicing clinicians. Increased collaboration is likely to contribute to the growing trend of multi-investigator projects, multiple-authored publications, and the subsequent conflicts regarding authorship credit and order. Recommendations and guidance on determining authorship credit and order are available in the literature; however, few concrete tools are available to assist in determining authorship credit and order. A model policy on authorship is presented. The model policy was (...) derived from recommendations published in the literature, in ethical standards, and in the editorial policies of both psychological and the biomedical fields. The model policy can be adopted by academic and clinical organizations, and is a useful tool for preventing authorship conflicts and encouraging collaboration in clinical research. (shrink)

The field of quantitative analysis is often mistaken to be a discipline free from ethical burdens. The quantitative financial analyst or “quant” profession holds a position of significant responsibility as the keeper of mathematical models used in complex derivative security pricing and risk management. Despite this responsibility very few postgraduate programs address the teaching of ethics and professional standards in their curriculum, and the credibility of the profession has suffered as a result of several high-profile financial losses. Some of these (...) failures could have been avoided and their impacts diminished if ethical considerations were integrated with quantitative method. Appropriate development in ethics education for quants is needed to identify points in the decision-making process where ethical questions can arise, and to explain how quants can protect stakeholders from the costs of unethical behaviour. An approach to ethics education needs to be flexible and allow for different methods to infuse ethical coverage into the course. Such an approach will go some way towards aligning the profession with other specialisations in banking and avoid the need for complex and unnecessary regulation. (shrink)

Quantitative analysts or “Quants” are a source of competitive advantage for financial institutions. They occupy the relatively powerful but often misunderstood role of modeling, structuring, and pricing complex financial instruments in the capital markets. But Quants often function in a discipline free from ethical burdens. Models used to price complex instruments are usually beyond the mathematical understanding of financial sector participants who rely heavily on the integrity of the Quant who built them. Although there has been some attempt to cover (...) the ethics of mathematics applied to the capital markets, designing a set of rules to guide the ethical behavior of Quants cannot be made explicit and remains inexpressible. Because Quants generally experience a sense of detachment from moral obligation, there is a growing need to convert moral detachment into engagement. Our framework is indebted to key elements of Wittgenstein’s practical ethics philosophy and Rawls’ justice principle. The burden of balancing justice as fairness as defined by Rawls with the inability to explicitly articulate ethical rules as defined by Wittgenstein must fall to the Quant. We propose that the threshold delineating the barrier between ethical detachment and engagement can only be defined by the Quants themselves. It is their moral duty to disclose their level of ethical engagement when their models are put into practice. (shrink)

This book concerns the nature of time and ordinary cases of persistence in Spinoza. The author argues for three major interpretive claims. First, that Spinoza is committed to an eternalist theory of time whereby all things (whether they seem to be past, present, or future) are equally real. Second, that a mode’s conatus or essence is a self-maintaining activity (not an inertial force or disposition.) Third, that modes persist through time in Spinoza’s metaphysics by having temporal parts (that is, different (...) parts at different times.) If this is correct, then a significant reinterpretation of Spinoza’s modal metaphysics is required. The book also puts Spinoza into dialogue with some recent work in analytic metaphysics. (shrink)

There is a perpetrator historiography of the Holocaust and a Jewish historiography of the Holocaust. The former has received the lion’s share of attention in bioethics, particularly in the form of warnings about medicine’s potential for complicity in human atrocity. However, stories of Jewish physicians during the Holocaust are instructive for positive bioethics, one that moves beyond warnings about what not to do. In exercising both explicit and introspective forms of resistance, the heroic work of Jewish physicians in the ghettos (...) and concentration camps tells us a great deal about the virtues and values of medicine. In this article, we frame the stories of four of these Jewish physicians in ways that are instructive for contemporary medicine. By far, the most widely recognized and discussed figure is Viktor Frankl, whose work on hope and the meaning of suffering remains essential insofar as medicine inherently confronts disease and death. Less discussed in bioethics and medical humanities are the cases of Mark Dworzecki, Karel Fleischmann, and Gisella Perl. Dworzecki’s efforts to encourage others in the Vilna Ghetto to document their experiences illustrates the power of narrative for the human experience and the notion of ethics as narrative in the face of suffering. Fleischmann’s art underscores not only the importance of reflective practices for professionals as a form of simultaneous introspection and testimonial, but illuminates hope amid sheer hopelessness. This hope, which was comparatively implicit in much of Fleishmann’s art, is explicated as a method by Frankl, becoming a form of therapy for both physicians wrestling with their professional work, and patients wrestling with their illnesses and diseases. Finally, Perl’s resistance to Mengele’s orders highlights the importance of moral action, not just reflective reaction. The experiences of each of these figures, while certainly located in the unique horrors of Holocaust Germany, portends lessons for today’s physicians faced with moral distress and ethical dilemma in the face of suffering, interpersonal relationships, and socio-political conflicts that increasingly test the professed ideals of medicine. In this article we briefly tell the story of each of these physicians and connect the lessons therein to contemporary medical practice. (shrink)

The synergies between viral and bacterial infections are well established. Most studies have been focused on the indirect mechanisms underlying this phenomenon, including immune modulation and alterations to the mucosal structures that promote pathogen outgrowth. A growing body of evidence implicates direct binding of virus to bacterial surfaces being an additional mechanism of synergy at the host–pathogen interface. These cross‐kingdom interactions enhance bacterial and viral adhesion and can alter tissue tropism. These bacterial–viral complexes play unique roles in pathogenesis and can (...) alter virulence potential. The bacterial–viral complexes may also play important roles in pathogen transmission. Additionally, the complexes are recognized by the host immune system in a distinct manner, thus presenting novel routes for vaccine development. These synergies are active for multiple species in both the respiratory and gastrointestinal tract, indicating that direct interactions between bacteria and virus to modulate host interactions are used by a diverse array of species. (shrink)