ObjectiveWe wished to explore Parkinson's disease subtypes by clustering analysis based on the multimodal magnetic resonance imaging indices amplitude of low-frequency fluctuation and gray matter volume. Then, we analyzed the differences between PD subtypes.MethodsEighty-six PD patients and 44 healthy controls were recruited. We extracted ALFF and GMV according to the Anatomical Automatic Labeling partition using Data Processing and Analysis for Brain Imaging software. The Ward linkage method was used for hierarchical clustering analysis. DPABI was employed to compare differences in ALFF (...) and GMV between groups.ResultsTwo subtypes of PD were identified. The “diffuse malignant subtype” was characterized by reduced ALFF in the visual-related cortex and extensive reduction of GMV with severe impairment in motor function and cognitive function. The “mild subtype” was characterized by increased ALFF in the frontal lobe, temporal lobe, and sensorimotor cortex, and a slight decrease in GMV with mild impairment of motor function and cognitive function.ConclusionHierarchical clustering analysis based on multimodal MRI indices could be employed to identify two PD subtypes. These two PD subtypes showed different neurodegenerative patterns upon imaging. (shrink)

James Wetzel in his recent book argues that Augustine's statements in 'Contra duas epistulas Pelagianorum' (hereafter, 'C2EP'), especially that "(t)he apostles...were free from consent to evil desire," directly contradict his long-held anti-Pelagian thesis. For in 'C2EP' and his other anti-Pelagian works, Augustine apparently defends the thesis that in this earthly life every human being consents to concupiscence daily. Thus, all need God's forgiveness daily. This is, Augustine argues, the true meaning of the Lord's Prayer. But this seems to contradict Augustine's (...) statement that the apostles "were free from consent to evil desire." By distinguishing different ways that an agent consents to concupiscence, the author argues that this seeming contradiction can be removed. Consequently, Augustine is consistent in his polemic against the Pelagians. (shrink)

This article analyzes a popular meme that has spread rapidly among Chinese internet users in the last few years, ‘garlic chives’ ( jiucai), as a self-mockery of the bio-economic subject in contemporary China. This metaphor refers to those ordinary Chinese people who are constantly lured to participate in all kinds of economic activities, but whose investments are destined to be consumed by the establishment. Through a close study of this popular meme and the social conditions from which it arises, this (...) article demonstrates two main features of the Chinese economic subject that supports the state’s economic sovereignty: the thriving of self-sufficient and rule-abiding individuals, and the quality of these individuals as hard working and capable of producing wealth on their own. This article offers a critique of PRC’s post-socialist governmentality, and it provides insights about the relation between the biological and the political in our complicated world order. (shrink)

This paper presents a refreshing new reading of Augustine's view on matter. It argues that Augustine's evolving view on matter from the negative to the positive, from the overly simplistic understanding of matter as something purely physical to a nuanced view of spiritual matter, played an essential role in the Confessions. Matter, in this new understanding, accounts for both space and time. As Augustine matured as a thinker, he saw matter's potentiality also positively as possibility for grace for the embodied (...) self and that which creates the depth of our being. Augustine owed this nuanced view of matter partly to its Plotinian origin but he modified it with his lived experience of faith. (shrink)

This article reappraises Zhu Xi's philosophy of women. First, it examines Zhu's descriptive texts. Second, it analyzes Zhu's didactic texts on li, qi, yin, yang, and gender. It finds that (i) surprisingly Zhu exhibited a level of flexibility toward women on subjects of education, property rights, and household management; (ii) his view on the male/yang and female/yin relationship was inconsistent; and (iii) improvement on Zhu's social-political teaching on women's role could result from a more consistent development of his metaphysics. When (...) thus modified, his metaphysics of yin-yang and li-qi could make a considerable contribution to contemporary feminist discourse. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:206 Feminist Studies 46, no. 1. © 2020 by Feminist Studies, Inc. Pang Laikwan Identity Politics and Democracy in Hong Kong’s Social Unrest Hong Kong’s anti-Extradition Law Amendment Bill (anti-ELAB) movement began with legislation proposed in February 2019 to allow the transfer of fugitives to jurisdictions with which the city lacks formal extradition treaties. The law quickly attracted a tremendous amount of criticism and generated enormous anxiety because (...) mainland China was one of those jurisdictions.1 In fact, many believe that this bill was proposed to allow the government of the People’s Republic of China (PRC) to transfer wanted persons of any nationality from Hong Kong to China, subject to a legal process that many view as highly dubious. A large-scale anti-government movement exploded in June 2019 when pro-establishment legislators in Hong Kong insisted on passing it, and millions of people took to the streets. The government waited three months to withdraw the bill, only doing so after some of the most violent confrontations between civilians and the police in Hong Kong’s history. With Beijing’s 1. The law was originally proposed after a Hong Kong man, who killed his pregnant girlfriend in Taiwan, could not be extradited back to Taiwan to stand trial for the murder due to the lack of formal extradition laws. The proposed law, which would be applied to Hong Kong citizens, foreign residents, and even people passing through on business or as tourists, is being opposed due to the fear that it would be used to extradite Hong Kong political/civil rights activists and dissidents to China, where they would be harshly punished. Pang Laikwan 207 support, the Hong Kong government has doggedly resisted negotiating with the protestors over other demands, such as setting up an independent inquiry into police misconduct. As people have become completely disillusioned with the government and their own futures, tensions have increased. Collapsing many of the city’s socioeconomic problems into one cause, the anti-ELAB movement is primarily an anti-authoritarian impulse motivated by the unifying power of the term “Hongkongers.” As the movement unfolds, one of the most popular slogans, “Add Oil, Hongkongers!” (meaning “Keep going, Hongkongers!”) gradually transformed into “Rebel, Hongkongers!” and “Revenge, Hongkongers!” showing the protestors ’ anger about unrestrained police violence and the Beijing regime behind it. The militarization associated with these protests is both worrisome and symptomatic. This short essay analyzes this movement and uses it as a vehicle to disentangle social and political identity. My concern is about how a large-scale political movement can realign identities to generate power from the bottom. I use an Arendtian approach to ground my theoretical orientation, asking: How can political actions be understood as the pursuit of freedom to transcend one’s biological and social identity? From an intersectional feminist angle, if we are aware that social discrimination operates within a complex network of simultaneous discriminations, real social change can only be envisioned using a broad political canvas. Hong Kong’s anti-Extradition Law Amendment Bill movement provides such a setting. Division and Inclusion “The people” might be the emptiest, but also the most powerful, phrase in the modern political lexicon. It can be used by politicians to justify groundless proposals or criticisms, but it is also the foundation and source of legitimacy for all modern political institutions. Indeed, the most basic meaning of democracy is “rule of the people,” which is impossible to avoid in any democratic imagination. As has been widely seen throughout the world, however, “the people” is often attached to various degrees of xenophobia—hatred of outsiders in the name of in-group solidarity. While the Hong Kong protestors’ courageous demands for the PRC to honor its promise to grant the city a high degree of autonomy have gained widespread international sympathy, thorny social divisions persist within the movement. 208 Pang Laikwan While Hong Kong has never been a united society, the anti-ELAB protests—like most social movements—have been highly divisive, splitting Hong Kong people apart. Most obviously, “the people” are divided by their political identifications, forming a primary antagonism between those who support the protests and those who do not, usually described... (shrink)

This article examines the rise and decline of the enthusiasm for intelligence testing in early twentieth-century China, focusing on the appeal, the challenges, and the critiques revolving around this psychological instrument. The introduction of intelligence testing reflected not only China’s urgent needs in modernizing its merit system, but also Chinese psychologists’ aspirations for pursuing exactitude and redefining the racial characteristics of their compatriots against foreign interpretations. But despite psychologists’ endeavors, the political and geographical fragmentation of Republican China troubled the epistemic (...) imperative of uniformity demanded by Euro-American psychometrics and therefore undermined the validity of measurement. Subsequently, the legitimacy of intelligence testing began to be questioned by several influential Chinese psychologists in the late 1920s and 30s. The difficulties in standardization and the hostility within the psychology community formed a vicious cycle, impeding the progress of nationwide testing. Through this history, the article demonstrates not only the elevation of measurement to epistemic authority in modern China, but also how its promise was challenged by a diverse and rapidly changing society. (shrink)

Is a reconciliation possible between Chinese philosophy and woman when taking into account infamous gender-oppressive cultural practices such as foot-binding, concubinage, etc., in premodern Chinese societies? The article tackles the complexity of the subject by calling the readers' attention to texts from Confucian classics that indeed support intellectual equality of the sexes and classless access to education, while noting diverging historical cultural evidences of women's education and their social status in premodern, modern, and postmodern Chinese societies. The article challenges the (...) belief that Confucian philosophy is unequivocally a sexist ideology to be a foregone conclusion. While not intending to exonerate Confucian philosophy from its opponents' charges, the article questions the adequateness of Western liberal feminism as the means to reappropriate Confucian philosophy. It suggests that a more culturally sensitive approach coupling with better historical and contextual analysis would prove to be both helpful and necessary. (shrink)

The pathogenesis of dengue haemorrhagic fever has been the subject of intense research and considerable controversy. One hypothesis proposes that the immune response in a sensitized host is the primary mechanism. In contrast, others have suggested that the disease is caused by a more virulent, variant strain of dengue virus. Recent advances in molecular biology and hybridoma technology are providing valuable clues toward a solution and illustrating the fact that the course of a human viral disease is often a net (...) result of unseparated interactions between host and virus. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2016 Heft: 209 Seiten: 149-165.

The first part of this paper examines the practice of informed treatment decisions in the protective medical system in China today. The second part examines how health care professionals in China perceive and carry out their responsibilities when relaying information to vulnerable patients, based on the findings of an empirical study that I had undertaken to examine the moral experience of nurses in practice situations. In the Chinese medical ethics tradition, refinement [jing] in skills and sincerity [cheng] in relating to (...) patients are two cardinal virtues that health care professionals are required to possess. This notion of absolute sincerity carries a strong sense of parental protectiveness. The empirical findings reveal that most nurses are ambivalent about telling the truth to patients. Truth-telling would become an insincere act if a patient were to lose hope and confidence in life after learning of his or her disease. In this system of protective medical care, it is arguable as to whose interests are being protected: the patient, the family or the hospital. I would suggest that the interests of the hospital and the family members who legitimately represent the patient's interests are being honoured, but at the expense of the patient's right to know. (shrink)

One INTRODUCTION: IN SEARCH OF THE VOICES OF NURSES IN CHINA Two motives launched this study to search for the voices of nurses in China. ...

Augustine of Hippo is often regarded as the champion of the doctrine of weakness of the will. John M. Rist in his 1994 'Augustine: Ancient Thought Baptized' draws an interesting analogy between Aristotle's 'akrasia' and Augustine's 'concupiscentia'. However, such an analogy without further qualification is defective and misleading because it implies that Augustine commits himself to the notion that since everyone is perpetually akratic and, thus, always morally blameworthy. I argue that, for Augustine, weakness of the will has equivocal meanings (...) and is manifested in four kinds of case--their scope goes far beyond Aristotle's discussion of 'akrasia' in Book Seven of the 'Nicomachean Ethics'. There are, therefore, considerable differences between Aristotle's and Augustine's account of weakness of the will. Consequently, for Augustine, moral responsibility for the moral agent also varies in each of the four cases. (shrink)

ZUSAMMENFASSUNGDer vorliegende Beitrag beschreibt das Gefühl der Gier als die misslungene Antwort auf die existenzielle Grundangst und Grundsorge des Menschen. Literatur deutet der Autor als Archiv der Gefühle, hier der Gier. Im zweiten Teil diskutiert der Essay die Deutung von Goethes Faust durch den Wirtschaftswissenschaftler Hans Christoph Binswanger, der die magische Struktur des Wirtschaftens und damit die Habgier als Motor einer auf Wachstum ausgerichteten Wirtschaft entdeckt. Über das Gleichnis vom reichen Kornbauern erschließt der Autor den biblischen Phänomenbestand der Gier: Die (...) Gier dokumentiert ein falsches Selbstverständnis. Ziel kann heute nur ein Selbstverständnis sein, das dem magischen Kern des Wirtschaftens entkommt.SUMMARYThis article describes the feeling of greed as an unsuccessful response to the existential fear and worry inherent to human existence. The author interprets literature as an archive of emotions, including that of greed. The second part of the essay discusses the economist Christoph Binswanger's interpretation of Goethe's ‘Faust’. He discovers the magical structure of the economy and thus describes greed as the impetus for a growth-directed economy. Interacting with the Parable of the Rich Fool , the author deduces the biblical understanding of the phenomenon of greed: greed documents a false understanding of the self. Our contemporary aim, then, should be reaching a conception of the self which escapes the magical core of the economy. (shrink)