In the yeast Saccharomyces cerevisiae three positive transcriptional control elements are activated by stress conditions: heat shock elements (HSEs), stress response elements (STREs) and AP‐1 responsive elements (AREs). HSEs bind heat shock transcription factor (HSF), which is activated by stress conditions causing accumulation of abnormal proteins. STREs mediate transcriptional activation by multiple stress conditions. They are controlled by high osmolarity via the HOG signal pathway, which comprises a MAP kinase module and a two‐component system homologous to prokaryotic signal transducers. AREs (...) bind the transcription factor Yap1p. The three types of control elements seem to have overlapping, but distinct functions. Some stress proteins encoded by HSE‐regulated genes are necessary for growth of yeast under moderate stress, products of STRE‐activated genes appear to be important for survival under severe stress and ARE‐controlled genes may mainly function during oxidative stress and in the response to toxic conditions, such as caused by heavy metal ions. (shrink)

J. Gordon Melton. Magic, Witchcraft, and Paganism in America:. Bibliography. New York: Garland. 1982. Pp. xi. 231. $44.00. cloth. L.C. 81‐43343. ISBN 0‐8240‐9377‐1.

Raw Feeling:. Philosophical Account of the Essence of Consciousness. Robert Kirk. Oxford, NY: Clarendon Press, 1994‐ ix. 251 pp. 42.00 (cloth).

Self and Consciousness: Multiple Perspectives. Edited by Frank S. Kessel. Pamela M. Cole. and Dale L. Johnson. Hillsdale, NJ: Lawrence Erlbaum Associates, 1992. 136 Pp. $16.50 (cloth).

The Fate of Place:. Philosophical History. Edward S. Casey. Berkeley: University of California Press, 1997. 495 pages. 45.00 (cloth);. 19.95 (paper).

Yearbook of Cross‐Cultural Medicine and Psychotherapy, Volume 1, 1990. Walter Andritzky. ed. Verlag, Postfach 11 03 68, Markgrafenstrabe 67, Berlin. 1991. 201pp. ISBN 3‐927408‐60‐3. $40 (paperback).

Haider’s target paper presents a fresh and inspiring look at the nature of grammar change. The overall impression of his approach is very convincing, especially his insistence on the point that language was not selected for communication – hence it is no adaptation to communicative use. Nevertheless, I think three topics are in need of further discussion and elaboration. First, I will discuss the question whether Haider’s conception of Darwinian selection covers all aspects of grammar change. Second, I will consider (...) the question of whether an approach that dispenses with UG (as Haider’s does) can explain why grammars are the way they are. Third, I will question Haider’s equation of grammar with the genotype and of speech with the phenotype and develop an alternative and more appropriate proposal where, among others, speech corresponds to behavior. (shrink)

Combining scientific understanding and Christian insight, this is a comprehensive and magisterial discussion of the theology of sexual ethics, ranging from sexual relationships and gender equality to birth control and artificial insemination.