Given that natural selection is so powerful at optimizing complex adaptations, why does it seem unable to eliminate genes (susceptibility alleles) that predispose to common, harmful, heritable mental disorders, such as schizophrenia or bipolar disorder? We assess three leading explanations for this apparent paradox from evolutionary genetic theory: (1) ancestral neutrality (susceptibility alleles were not harmful among ancestors), (2) balancing selection (susceptibility alleles sometimes increased fitness), and (3) polygenic mutation-selection balance (mental disorders reflect the inevitable mutational load on the thousands (...) of genes underlying human behavior). The first two explanations are commonly assumed in psychiatric genetics and Darwinian psychiatry, while mutation-selection has often been discounted. All three models can explain persistent genetic variance in some traits under some conditions, but the first two have serious problems in explaining human mental disorders. Ancestral neutrality fails to explain low mental disorder frequencies and requires implausibly small selection coefficients against mental disorders given the data on the reproductive costs and impairment of mental disorders. Balancing selection (including spatio-temporal variation in selection, heterozygote advantage, antagonistic pleiotropy, and frequency-dependent selection) tends to favor environmentally contingent adaptations (which would show no heritability) or high-frequency alleles (which psychiatric genetics would have already found). Only polygenic mutation-selection balance seems consistent with the data on mental disorder prevalence rates, fitness costs, the likely rarity of susceptibility alleles, and the increased risks of mental disorders with brain trauma, inbreeding, and paternal age. This evolutionary genetic framework for mental disorders has wide-ranging implications for psychology, psychiatry, behavior genetics, molecular genetics, and evolutionary approaches to studying human behavior. (Published Online November 9 2006) Key Words: adaptation; behavior genetics; Darwinian psychiatry; evolution; evolutionary genetics; evolutionary psychology; mental disorders; mutation-selection balance; psychiatric genetics; quantitative trait loci (QTL). (shrink)

Moral patients deserve moral consideration and concern – they have moral standing. What factors drive attributions of moral standing? Understanding these factors is important because it indicates how broadly individuals conceptualize the moral world, and suggests how they will treat various entities, both human and non-human. This understanding has recently been advanced by a series of studies conducted by both psychologists and philosophers, which have revealed three main drivers of moral standing: the capacity to suffer, intelligence or autonomy, and the (...) nature of an entity's disposition. These studies have also revealed causal links between moral standing and other variables of interest, namely, mental state attributions and moral behavior. In this review, I consider this recent research, aiming to clarify what the balance of evidence indicates about how moral standing is judged and about its links to mind perception and behavior. I conclude by suggesting open questions for future research on this exciting topic. (shrink)

This paper examines how communities of naturalists in mid-nineteenth-century Britain were formed and solidified around the shared practices of public meetings, the publication and reading of periodicals, and the making and printing of images. By focusing on communities of naturalists and the sites of their communication, this article undermines the distinction between amateur and professional scientific practice. Building on the notion of imagined communities, this paper also shows that in some cases the editors and illustrators utilized imagery to construct a (...) specifically British naturalist community. Following three ‘amateur’ natural-history periodicals (Science Gossip,Midland Naturalistand theJournal of the Quekett Microscopical Club) the article demonstrates how the production and reproduction of natural history in the nineteenth century was contingent on community debate – and that this debate both was highly visual and moved across printed and geographical boundaries. This paper investigates images both for their purported success and for their ascribed value to natural history. Additionally, it considers the debates over their limitations and alleged failures of printing. Altogether, the article argues that investigating the communal practices of observation, writing, drawing and engraving allows for a better understanding of the shared practices of nineteenth-century natural history. (shrink)

In this book an international and multidisciplinary team addresses significant ethical questions about the rights to access, manage and interpret the material remains of the past.

It is critically important for emerging professionals in education to be sensitised to the ethical and moral responsibilities of their practice throughout their training and beyond. There is a wide disparity in contemporary practice in this regard, which points to a need for greater clarity and consistency in our thinking about ethics within education. Ethics in Education attempts to meet this need, and will be a valuable resource for students, teachers and researchers in education, health and social sciences. Most significantly, (...) the increasing awareness of the importance of ethics, diversity and social pedagogy in the teacher education curriculum will ensure that this book becomes essential reading or recommended reading for initial teacher education and CPD courses in education. The Editors have gathered together an exciting and dynamic group of contributors across many fields of English education, and asked them to help rethink the role of ethics in education in the 21st century. The types of questions that we address include: Do we have a shared view of ethical practice? What are the values that underpin ethical practice? What are our ethical responsibilities as pedagogues? (shrink)

: Descartes provides an original and puzzling argument for the traditional theological doctrine that the world is continuously created by God. His key premise is that the parts of the duration of anything are "completely independent" of one another. I argue that Descartes derives this temporal independence thesis simply from the principle that causes are necessarily simultaneous with their effects. I argue further that it follows from Descartes's version of the continuous creation doctrine that God is the instantaneous and total (...) cause of everything that happens, and that this is just what his physics demands. But although God is the total cause of everything, he is not the only cause, since Descartes considers it obvious that finite minds have the power to move bodies. In the face of this apparent paradox, several recent commentators have suggested that Descartes accepted the late scholastic view that God and finite causes somehow collaborate or concur in the production of numerically identical effects. But close examination reveals that the case for Cartesian concurrentism is weak. Fortunately, there is a simpler and more fruitful solution to the problem of reconciling divine and human action. I argue that that in Descartes's world certain motions, such as voluntary movements of our bodies, are causally overdetermined This account allows Descartes to avoid occasionalism without embracing an elaborate metaphysics of secondary causality. Finally, I argue that the overdeterminist interpretation sheds new light on two longstanding problems of Cartesian metaphysics. First, it resolves a serious difficulty with a standard reading of Descartes's conception of human freedom. Second, it offers a novel approach to the old problem of reconciling genuine human action with the principle of the conservation of total quantity of motion. (shrink)

Introduction Someone comes and says something. Without really needing to think, I understand what is said, refer it without difficulty to familiar codes, ...

When Michael Hunter first publicized the idea of ‘Psychoanalysing Robert Boyle’ I understood that his main aim was to test three competing psychoanalytical theories against the historical evidence provided by the life and work of Robert Boyle. Although this would have been a valuable exercise, and one that the British Society for the History of Science meeting partly engaged, the papers by Brett Kahr, John Clay and Karl Figlio published here raise some far more compelling issues which I shall explore (...) in the ensuing discussion. Before turning to this discussion I offer a few introductory remarks. (shrink)

This paper sets out to examine the changes which took place in Thomas Young's concepts of the ether between 1799 and 1807. During the earlier part of this period he supposed the ether to consist of mutually repelling subtle particles which are attracted to particles of matter. Hence, he considered that the ether is denser within dense bodies than in rare ones. Furthermore, Young proposed that the ether density does not change abruptly at an interface; instead the denser ether extends (...) beyond the geometrical limit of a body to form an atmosphere around it. As this hypothesis of an atmosphere of dense ether surrounding material bodies will be the central subject of this paper, I shall in future refer to it as the ether distribution hypothesis. (shrink)

Seventeenth-century authors frequently infer the attributes of time by analogy from already established features of space. The rationale for this can be traced back to Aristotle's analysis of time as ?the number of movement?, where movement requires a prior understanding of spatial magnitude. Although these authors are anti-Aristotelian, they were concerned, contra Aristotle, to establish the existence of ?empty space?, and a notion of absolute space which fit this idea. Although they had no independent rationale for the existence of absolute (...) time, it seemed to go with absolute space, and they drew on a long tradition of space-time parallelism in securing this. (shrink)

Are humans at their core seekers of their own pleasure or cooperative members of society? Paradoxically, they are both. Pleasure-seeking can take place only within the context of what works within a defined community, and central to any community are the evolved codes and principles guiding appropriate behavior, or morality. The complex interaction of morality and self-interest is at the heart of Geoffrey M. Hodgson’s approach to evolutionary economics, which is designed to bring about a better understanding of human (...) behavior. In From Pleasure Machines to Moral Communities, Hodgson casts a critical eye on neoclassical individualism, its foundations and flaws, and turns to recent insights from research on the evolutionary bases of human behavior. He focuses his attention on the evolution of morality, its meaning, why it came about, and how it influences human attitudes and behavior. This more nuanced understanding sets the stage for a fascinating investigation of its implications on a range of pressing issues drawn from diverse environments, including the business world and crucial policy realms like health care and ecology. This book provides a valuable complement to Hodgson’s earlier work with Thorbjørn Knudsen on evolutionary economics in Darwin’s Conjecture, extending the evolutionary outlook to include moral and policy-related issues. (shrink)

At Cratylus 385b–c, Plato appears to argue that names have truth-value. Critics have almost universally condemned the argument as fallacious. Their case has proven so compelling that it has driven editors to recommend moving or removing the argument from its received position in the manuscripts. I argue that a close reading of the argument reveals it commits no fallacy, and its purpose in the dialogue justifies its original position. I wish to vindicate the manuscript tradition, showing that the argument establishes (...) that there is subject matter for investigation, and there is a correctness of names. (shrink)

Subtle-body practices are found particularly in Indian, Indo-Tibetan and East Asian societies, but have become increasingly familiar in Western societies, especially through the various healing and yogic techniques and exercises associated with them. This book explores subtle-body practices from a variety of perspectives, and includes both studies of these practices in Asian and Western contexts. The book discusses how subtle-body practices assume a quasi-material level of human existence that is intermediate between conventional concepts of body and mind. Often, this level (...) is conceived of in terms of an invisible structure of channels, associated with the human body, through which flows of quasi-material substance take place. Contributors look at how subtle-body concepts form the basic explanatory structure for a wide range of practices. These include forms of healing, modes of exercise and martial arts as well as religious practices aimed at the refinement and transformation of the human mindbody complex. By highlighting how subtle-body practices of many kinds have been introduced into Western societies in recent years, the book explores the possibilities for new models of understanding which these concepts open up. It is a useful contribution to studies on Asian Religion and Philosophy. (shrink)

"The four essays in this volume constitute Derrida's most explicit and sustained reflection on the art work as pictorial artifact, a reflection partly by way of philosophical aesthetics, partly by way of a commentary on art works and art scholarship. The illustrations are excellent, and the translators, who clearly see their work as both a rendering and a transformation, add yet another dimension to this richly layered composition. Indispensable to collections emphasizing art criticism and aesthetics."—Alexander Gelley, _Library Journal_.

Presidential addresses offer an opportunity to reflect on the history of our subject and where the history of science stands in our own day. Such reflections are particularly appropriate with the fiftieth anniversary of the founding of the British Society for the History of Science which is marked in 1997. Some may consider that looking back over our past is either an unacceptable luxury or an occasion for the kind of celebration that can all too easily degenerate into hagiography and (...) an excuse to rake over the past in a thoroughly uncritical manner. This address – and I trust the events of 1997 – will try to avoid such excesses and instead contribute to the historiography of our subject. (shrink)

Dramatic, profound and far-reaching changes are being visited on schools worldwide that have their genesis a long way from the classroom but which impact heavily on teachers and their work. Most of this reform has been achieved with little or no involvement of teachers themselves. This book sets out to survey the contemporary context of what is happening to the work of teaching, and focuses on Advanced Skills Teachers. It shows how teachers are 'speaking' the changes that are occuring to (...) their work in protracted economically rationalist times. Arguing against the discourses of economy as the major shaping force, the authors present a persuasive case for focusing on the discourses of teaching itself as the only feasible and adequate basis on which to make sense of teaching. And by presenting a range of voices of practising teachers - allowing them to speak for themselves about the difficulty of trying to translate policy-makers' intentions into words and actions - the book graphically illustrates the devastating long-term consequences for the future of schools of poorly-conceptualised reform policies. (shrink)

It has sometimes been claimed that the perceived badness of an act can in some circumstances, or for some agents, be a reason for performing it. The present paper challenges this claim, arguing that it is hard to make sense of the idea that a negative evaluation of an action can provide an intelligible reason for doing it. Apparent counter‐examples are discussed and dismissed and the paper concludes with some general reflections on the relationship between evaluation and motivation.

The argument I defend in this paper challenges whether Waldron’s explanation of the conditions required for a moral right to satisfy its autonomy-promoting function is the best one available. It questions the suitability of Waldron’s preferred taxonomy of moral action, where acts are divided into: (1) those that are morally required; (2) those that are morally prohibited; and (3) those that are morally indifferent, advocating instead for a binary classification consisting of: (a) actions that admit of reasonable moral disagreement; and (...) (b) actions that do not admit of reasonable moral disagreement. My claim is that the protective sphere moral rights set up in organizing the moral relations among persons is applicable only to the former category—namely, actions that admit of reasonable moral disagreement. Actions that do not admit of reasonable moral disagreement will either: (b’) not normally demand a right against interference in the first place (if the action is unquestionably permissible); or (b”) fail to admit of a right against interference at all (if the action is unquestionably impermissible). This competing explanation allows us to preserve the autonomy-promoting conception of moral rights Waldron endorses while avoiding a number of its suspect implications. (shrink)

Cultural Heritage, Ethics and Contemporary Migrations breaks new ground in our understanding of the challenges faced by heritage practitioners and researchers in the contemporary world of mass migration, where people encounter new cultural heritage and relocate their own. It focuses particularly on issues affecting archaeological heritage sites and artefacts, which help determine and maintain social identity, a role problematised when populations are in flux. This diverse and authoritative collection brings together international specialists to discuss socio-political and ethical implications for the (...) management of archaeological heritage in global society. With contributions by authors from a range of disciplinary backgrounds, including archaeologists, philosophers, cultural historians and custodians of cultural heritage, the volume explores a rich mix of contrasting, yet complementary, viewpoints and approaches. Among the topics discussed are the relations between culture and identity; the potentialities of museums and monuments to support or subvert a people's sense of who they are; and how cultural heritage has been used to bring together communities containing people of different origins and traditions, yet without erasing or blurring their distinctive cultural features. Cultural Heritage, Ethics and Contemporary Migrations is a crucial text for archaeologists, curators, policymakers and others working in the heritage field, as well as for philosophers, political scientists and other readers interested in the links between immigration and cultural heritage. (shrink)

The contributions in this book address the relation between evil, symbolism and psychoanalysisc by focusing on the two works of Riœur in which these topics play the most prominent role: The Symbolism of Evil and Freud and Philosophy. Furthermore, the bilingual book includes contributions that examine the relation between evil, symbolism and psychoanalysis in Ricœur’s work in a more general fashion, by investigating his philosophy as a whole. It brings together both French and English chapters from leading Ricœur scholars from (...) over the world. The international multilinguistic perspective reflects Ricœur’s spirit who said that when he worked on a book, all of the others were simultaneously open on his writing table. It is a groundbreaking work to those interested in Ricœur, Freud and religion. (shrink)

The Allegory of the Cave (Pl. Resp. 514a1–520e2) is often analyzed in terms of metaphysical, epistemological, political, and psychic hierarchies that are clarified and reinforced by philosophical education. But the Allegory also contains an important historical allusion to the silver mining that took place in classical Attica. Examining the Cave in light of the enslaved miners around Lavrio leads us to reconsider the philosophical ‘liberation’ (λύσιν … τῶν δεσμῶν, 515c4) at the Allegory’s heart in the context of Athenian slavery and (...) Plato’s thoughts on the practice. Elsewhere in his work Plato generally uses servile metaphors in two ways: to depict ‘bad’ internal psychic subjection and ‘good’ submission to logos as manifested in various entities. This historical dimension of the Allegory works to undermine the ostensible naturalness of the slave/citizen distinction and suggest that philosophical education has the potential to ‘free’ the former and ‘subjugate’ the latter. The implication that these juridical categories are, to an extent, arbitrary and mutable reveals important differences between Plato’s views and those of his classical peers, and it adds to the dialogue’s protreptic dimension for its readers then and now. (shrink)

An often overlooked tension in liberal theory turns on its commitment to procedural accounts of legitimacy on the one hand, and to the robust protection of the right of citizens to dissent on the other. To the extent that one evaluates legitimate decision-making on the basis of the procedures that bear on it, determining how extra-procedural expressions of dissent fit into the picture becomes a complex undertaking. This is especially true if one accepts that protecting extra-procedural expressions of dissent is (...) itself foundational to the overall legitimacy of the state. My aim in this paper is to explore some of the implications that follow from this tension. The paper proceeds in two parts. In the first part, I review the political grounds that support a protection on dissent. By drawing on its republican foundations, I argue that the functional role that the right to dissent serves in complex political communities is intimately connected to concerns over legitimacy. I claim that for the right to perform its function successfully, protections must be placed on both procedural and extra-procedural forms of dissent. The second part of the paper issues a direct challenge to procedural accounts of legitimacy. If a protection on citizen dissent is vital to legitimating government action, and if that protection necessarily extends to both procedural and extra-procedural forms of dissent, it follows that legitimacy cannot be captured by procedure alone—even procedures that secure the fair and equal participation by all affected parties. (shrink)