An interview with Gail Weiss concerning her interests and influences, especially the body and embodiment.

Since the first draft of the human genome was published in 2001, DNA sequencing technology has advanced at a remarkable pace. Launched in 1990, the Human Genome Project sought to sequence all three billion base pairs of the haploid human genome, an endeavor that took more than a decade and cost nearly three billion dollars. The subsequent development of so-called “next generation” sequencing methods has raised the possibility that real-time, affordable genome sequencing will soon be widely available. Currently, NGS methods (...) can be used to sequence up to 60 billion base pairs per day. Whole-genome sequencing costs an estimated $5,000-10,000, with that number predicted to fall to $1000 in the near future.In the past few years, the availability of high-throughput NGS methods has led to a proliferation of potential and actual clinical applications for NGS. NGS therefore has the potential to usher in the long-awaited era of personalized medicine. (shrink)

How are we to think and act constructively in the face of today’s environmental and political catastrophes? Gail Stenstad finds inspiring answers in the thought of German philosopher Martin Heidegger. Rather than simply describing or explaining Heidegger’s transformative way of thinking, Stenstad’s writing enacts it, bringing new insight into contemporary environmental, political, and personal issues. Readers come to understand some of Heidegger’s most challenging concepts through experiencing them. This is a truly creative scholarly work that invites all readers to (...) carry Heidegger’s transformative thinking into their own areas of deep concern. (shrink)

I distinguish between two senses in which feminists have argued that the knower is social: 1. situated or socially positioned and 2. interdependent. I argue that these two aspects of the knower work in cooperation with each other in a way that can produce willful hermeneutical ignorance, a type of epistemic injustice absent from Miranda Fricker's Epistemic Injustice. Analyzing the limitations of Fricker's analysis of the trial of Tom Robinson in Harper Lee's To Kill a Mockingbird with attention to the (...) way in which situatedness and interdependence work in tandem, I develop an understanding of willful hermeneutical ignorance, which occurs when dominantly situated knowers refuse to acknowledge epistemic tools developed from the experienced world of those situated marginally. Such refusals allow dominantly situated knowers to misunderstand, misinterpret, and/or ignore whole parts of the world. (shrink)

The paper explores the methodology and goals of H. Odera Oruka’s sage philosophy project. Oruka interviewed wise persons who were mostly illiterate and from the rural areas of Kenya to show that a long tradition of critical thinking and philosophizing exists in Africa, even if there is no written record. His descriptions of the role of the academic philosopher turned interviewer varied, emphasizing their refraining from imposition of their own views (the social science model), their adding their own ideas (like (...) Plato), or their midwifery in helping others give birth to their own ideas (like Socrates). The accuracy and consistency of the various metaphors used by Oruka is the main focus of the article’s analysis. The article sums up the shortcomings of Oruka’s method as well as its strengths and concludes with Oruka’s challenge to academic philosophers to rethink their own roles in society. (shrink)

If social, political, and material transformation is to have a lasting impact on individuals and society, it must be integrated within ordinary experience. Refiguring the Ordinary examines the ways in which individuals' bodies, habits, environments, and abilities function as horizons that underpin their understandings of the ordinary. These features of experience, according to Gail Weiss, are never neutral, but are always affected by gender, race, social class, ethnicity, nationality, and perceptions of bodily normality. While no two people will experience (...) the ordinary in exactly the same way, the multiplicities, possibilities, overlaps, and limitations of day-to-day horizons are always intersubjectively constituted. Weiss turns her attention to changing the conditions and experiences of oppression from ordinary to extraordinary. This book is an impressive phenomenological, feminist reading of the complexities of human experience.M. V. Marder, University of Toronto, Feb. 2009. (shrink)

Meno's Paradox from Socrates to Sextus Gail Fine. sense that they consider the issues it raises; and they argue, against its conclusion, that inquiry is possible. Like Plato and Aristotle, they also explain what makes inquiry possible; and they do ...

Abstractabstract:Recent clinical trials of psychedelic drugs aim to treat a range of psychiatric conditions in adults. MDMA and psilocybin administered with psychotherapy have received FDA designation as "breakthrough therapies" for post-traumatic stress disorder (PTSD) and treatment-resistant depression (TRD) respectively. Given the potential benefit for minors burdened with many of the same disorders, calls to expand experimentation to minors are inevitable. This essay examines psychedelic research conducted on children from 1959 to 1974, highlighting methodological and ethical flaws. It provides ethics and (...) policy recommendations for psychedelics research involving children and adolescents, including recognizing that the psychedelic experience is an ineffable one that makes informed proxy consent for parents, guardians, and others especially challenging. Psychedelic experiences are associated with novel benefits and risks, such as significant personality changes, shifts in fundamental values, and possible re-exposure to traumatic memories. These effects may alter the process of personality development in minors. Recommendations for ethically sound psychedelics research in minors include strict adherence to eligibility criteria, including a comprehensive family and individual psychiatric, substance use, and trauma history. An age-appropriate assent process that includes considerations related to the use of therapeutic touch should be developed. In addition, oversight by data safety monitoring boards and patient and family advocates, coupled with the adoption of pharmacoequity best practices, will help to ensure safety and fairness of psychedelics research in children. (shrink)

Little is known about health care professionals’ perceptions regarding what it means to treat patients and families with respect and dignity in the intensive care unit (ICU) setting. To address this gap, we conducted nine focus groups with different types of health care professionals (attending physicians, residents/fellows, nurses, social workers, pastoral care, etc.) working in either a medical or surgical ICU within the same academic health system. We identified three major thematic domains, namely, intrapersonal (attitudes and beliefs), interpersonal (behaviors), and (...) system (contextual) factors that influence treatment with respect and dignity. Participants suggested strategies for improving treatment of patients and families in the ICU with respect and dignity, as well as the related need for enhancing respect among the multidisciplinary team of clinicians. Implementing these strategies will require innovative educational interventions and leadership. Future research should focus on the design and evaluation of such interventions on the quality of care. (shrink)

This volume draws together a series of thirteen essays on ancient epistemology by Gail Fine. She discusses knowledge, belief, subjectivity, and scepticism in Plato, Aristotle, and the Pyrrhonian sceptics. They consider such questions as: is episteme knowledge? Is doxa belief? Do the ancientshave the notion of subjectivity? Do any of them countenance external world scepticism? Several essays compare these philosophers with one another, as well as with more recent discussions of knowledge, belief, subjectivity, and scepticism, asking how if at (...) all the ancient discussions of these topicsdiffer from more recent ones. In exploring these issues, the essays often make use of the distinction between concepts and conceptions, between an abstract account of something, and more determinate ways of filling it in. Together they compose a rich set of investigations, illuminating ancientperspectives on the central questions in epistemology. (shrink)

The field of bioethics has evolved over the past half-century, incorporating new domains of inquiry that signal developments in health research, clinical practice, public health in its broadest sense and more recently sensitivity to the interdependence of global health and the environment. These extensions of the reach of bioethics are a welcome response to the growth of global health as a field of vital interest and activity. This paper provides a critical interpretive review of how the term “global health ethics” (...) has been used and defined in the literature to date to identify ethical issues that arise and need to be addressed when deliberating on and working to improve the discourse on ethical issues in health globally. Selected publications were analyzed by year of publication and geographical distribution, journal and field, level of engagement, and ethical framework. Of the literature selected, 151 articles were written by authors in high-income countries, as defined by the World Bank country classifications, 8 articles were written by authors in low- or middle-income countries, and 13 articles were collaborations between authors in HIC and LMIC. All of the articles selected except one from 1977 were published after 1998. Literature on global health ethics spiked considerably from the early 2000s, with the highest number in 2011. One hundred twenty-seven articles identified were published in academic journals, 1 document was an official training document, and 44 were chapters in published books. The dominant journals were the American Journal of Bioethics, Developing World Bioethics, and Bioethics. We coded the articles by level of engagement within the ethical domain at different levels: interpersonal, institutional, international, and structural. The ethical frameworks at use corresponded to four functional categories: those examining practical or narrowly applied ethical questions; those concerned with normative ethics; those examining an issue through a single philosophical tradition; and those comparing and contrasting insights from multiple ethical frameworks. This critical interpretive review is intended to delineate the current contours and revitalize the conversation around the future charge of global health ethics scholarship. (shrink)

Lately, several commentators have argued that there are significant differences between ancient and modern skepticism. For example, it has been argued that ancient skeptics disavow belief, whereas the moderns disavow only knowledge. It has also been argued that the scope of ancient skepticism is considerably less radical than that of modern skepticism: unlike the moderns, the ancients do not question whether they have bodies or whether there is an external world furnished with the sorts of objects we generally take there (...) to be. They do not suspend judgment as to whether, for example, honey exists, but only as to whether it is sweet. One explanation that has been given for the allegedly modest scope of ancient skepticism is its practical concern: ancient skepticism is a way of life, one that is supposed to secure the skeptic’s happiness. But, according to Myles Burnyeat, “[s]uch being his primary concern, he cannot doubt in a completely general way his ability to act in the world.” Modern skepticism, by contrast, is said to be “a strictly methodological affair,” with the result that, unlike ancient skeptics, modern ones can act in the face of radical skepticism. (shrink)

Plato on Knowledge and Forms brings together a set of connected essays by Gail Fine, in her main area of research since the late 1970s: Plato's metaphysics and epistemology. She discusses central issues in Plato's metaphysics and epistemology, issues concerning the nature and extent of knowledge, and its relation to perception, sensibles, and forms; and issues concerning the nature of forms, such as whether they are universals or particulars, separate or immanent, and whether they are causes. A specially written (...) introduction draws together the themes of the volume, which will reward the attention of anyone interested in Plato or in ancient metaphysics and epistemology. (shrink)

This article explores the development of a novel biomedical research organism, and its potential to remake the species and spaces of translational medicine. The humanized mouse is a complex experimental object in which mice, rendered immunodeficient through genetic alteration, are engrafted with human stem cells in the hope of reconstituting a human immune system for biomedical research and drug testing. These chimeric organisms have yet to garner the same commentary from social scientists as other human–animal hybrid forms. Yet, they are (...) rapidly being positioned as central to translational medicine in immunological research and pharmaceutical development. This article explores the complex relations between species and spaces they seek to enact. Humanizing mice simultaneously moves these animal forms towards the intimate geographies of corporeal equivalence with humans and the expansive geographies of translational research. These multiple trajectories are achieved by the way humanized mice function as both uncertain ‘epistemic things’ and as expansive ‘collaborative things’, articulating mouse genetics with other research, notably stem cell science. In the context of post-genomics, their indeterminacy is critical to their collaborative value; their expansive potential follows as much from their biological openness as from specific expectations. Yet, these new research organisms have both accumulative and disruptive capacities, for there are patterns of interference between these trajectories, remaking boundaries between experimental practices and clinical contexts. (shrink)

Spellman argues that Aristotle developed his views about substance in response to Plato’s theory of forms. In particular, she argues that Aristotelian substances are as much like Platonic forms as possible, minus the latter’s separation. Whether ASs are like PFs depends, of course, not only on what one takes ASs to be like, but also on what one takes PFs to be like; accordingly, Spellman provides accounts of both. She argues that ASs are what she calls specimens of natural kinds. (...) A specimen of a natural kind is not Socrates, but Socrates-qua-human-being: Socrates insofar as he is a human being. She argues that Socrates, and Socrates-qua-human-being are numerically the same, but not identical. They are not identical, because not everything true of Socrates is true of Socrates-qua-human-being. Socrates, for example, is snub-nosed, but Socrates-qua-human-being is not; for the latter has all and only the properties contained in the definition of human being. (shrink)

This editorial critically engages with the understanding of openness by attending to how notions of presence and absence come bundled together as part of efforts to make open. This is particularly evident in contemporary discourse around data production, dissemination, and use. We highlight how the preoccupations with making data present can be usefully analyzed and understood by tracing the related concerns around what is missing, unavailable, or invisible, which unvaryingly but often implicitly accompany debates about data and openness.

The Peri ide^on is the only work in which Aristotle systematically sets out and criticizes arguments for the existence of Platonic forms. Gail Fine presents the first full-length treatment in English of this important but neglected work. She asks how, and how well, Aristotle understands Plato's theory of forms, and why and with what justification he favors an alternative metaphysical scheme. She examines the significance of the Peri ide^on for some central questions about Plato's theory of forms--whether, for example, (...) there are forms corresponding to every property or only to some, and if only to some, then to which ones; whether forms are universals, particulars or both; and whether they are meanings, properties or both. Fine also provides a general discussion of Plato's theory of forms, and of our evidence about the Peri ide^on and its date, scope, and aims. While she pays careful attention to the details of the text, she also relates it to contemporary philosophical concerns. The book will be valuable for anyone interested in metaphysics ancient or modern. (shrink)

Working with interactional data, one sometimes observes that a type of behavior seems to be produced a great deal by one category of persons and not all that much by another category. But when put to the test of a straightforward count, the observation does not hold up: Category X does not after all do this thing significantly more often than Category Y does. It may then be that the apparent skewing of the behavior’s distribution across categories is the result (...) of selective observation; noticing with greater frequency those cases which conformed to some biased notion held by the observer of how these categories behave. But there seems to be another possibility. It may be that the observation has located, but only roughly and partially described, a complex of behaviors which the observation can then be seen to reflect, refer to, or constitute a ‘gloss’ for. (shrink)

(1995). A Feminist Sociologist Responds to Daniel's 'Exclusion and Emphasis Reframed as a Matter of Ethics' Ethics & Behavior: Vol. 5, No. 4, pp. 369-371.

This paper considers and criticizes david armstrong's defense in his book of an allegedly nonrelational version of realism, "universals and scientific realism". It also challenges his claim that plato, But not aristotle, Held a relational version of realism.

In much the same way that genomic technologies are changing the complexion of biomedical research, the issues they generate are changing the agenda of IRBs and research ethics. Many of the biggest challenges facing traditional research ethics today — privacy and confidentiality of research subjects; ownership, control, and sharing of research data; return of results and incidental findings; the relevance of group interests and harms; the scope of informed consent; and the relative importance of the therapeutic misconception — have become (...) important policy issues over the last 20 years because of the ways they have been magnified by genomic research efforts. Research that examines the ethical, legal, and social implications of human genomics research has become a burgeoning international field of scholarship over the last 20 years, thanks in part to its support first by the genome research funding bodies in the U.S. and then by national science agencies in other countries. (shrink)

This investigation examines the discursive history and contemporary courtroom discourse of expert witnesses in Anglo-American courts, incorporating the methods of Michel Foucault into a Critical Discourse Analysis framework. The history of experts is marked by a profound discontinuity in the role of experts, during the late medieval period, with experts relegated to a witness role instead of a juror role - that of the privately knowledgeable investigator - they previously held. Examination of the discourse of contemporary experts in three high-profile (...) US trials documents a different witness status for experts along three parameters: amplification of question responses; the use of the contrastive discourse marker well to express professional disagreement with their interlocutors; and the embedding of professional practices into so clauses. These parameters stand in sharp contrast to ordinary witness discourse. The study concludes with a discussion of the stakes in legal control of expert witnesses including asymmetrical access to experts by economic status, the possible suppression of some expert testimony by recent US Supreme Court decisions, and the hierarchicalization of expert knowledge. (shrink)

Plato is the best known, and continues to be the most widely studied, of all the ancient Greek philosophers. The twenty-one commissioned articles in The Oxford Handbook of Plato provide in-depth and up-to-date discussions of a variety of topics and dialogues. The result is a useful state-of-the-art reference to the man many consider the most important philosophical thinker in history.

I analyze Jason Stanley’s model for how propaganda works, paying close attention to Stanley’s own rhetoric. I argue that Stanley’s language be supplemented with a vocabulary that helps us to attend to what sorts of things move democratic knowers (epistemically speaking), what sorts of things do not, and why. In addition, I argue that the reasonableness necessary for considering the views of others within democratic deliberation ought to be understood, not as an empathic, but as an interactive capacity. Finally, I (...) critique some of the ways in which Stanley speaks about the marginalized populations he aims to support.Analizo el modelo debido a Jason Stanley sobre el modo en que funciona la propaganda, prestando atención en particular a la retórica del propio Stanley. Argumento la conveniencia de que el lenguaje de Stanley se complemente con un vocabulario que nos ayude a prestar atención a las cosas que motivan a los agentes de conocimiento democráticos (epistémicamente hablando), a las que no lo hacen, y por qué. Adicionalmente, argumento que la razonabilidad que se necesita para tomar en consideración los puntos de vista de otros en la deliberación democrática debería entenderse como una capacidad no de empatía, sino de interacción. Finalmente, critico alguna de las formas en que Stanley habla de las poblaciones marginadas a las que quiere dar apoyo. (shrink)

Large-scale sequencing tests, including whole-exome and whole-genome sequencing, are rapidly moving into clinical use. Sequencing is already being used clinically to identify therapeutic opportunities for cancer patients who have run out of conventional treatment options, to help diagnose children with puzzling neurodevelopmental conditions, and to clarify appropriate drug choices and dosing in individuals. To evaluate and support clinical applications of these technologies, the National Human Genome Research Institute and National Cancer Institute have funded studies on clinical and research sequencing under (...) the Clinical Sequencing Exploratory Research program as well as studies on return of results. Most of these studies use sequencing in real-world clinical settings and collect data on both the application of sequencing and the impact of receiving genomic findings on study participants. They are occurring in the context of controversy over how to obtain consent for exome and genome sequencing. (shrink)

Lecturer in social foundations of education and women's studies, Victoria College, Australia.

Representing a new generation of theorists reaffirming the radical dimensions of art, Gail Day launches a bold critique of late twentieth-century art theory and its often reductive analysis of cultural objects. Exploring core debates in discourses on art, from the New Left to theories of "critical postmodernism" and beyond, Day counters the belief that recent tendencies in art fail to be adequately critical. She also challenges the political inertia that results from these conclusions. Day organizes her defense around critics (...) who have engaged substantively with emancipatory thought and social process: T. J. Clark, Manfredo Tafuri, Fredric Jameson, Benjamin H. D. Buchloh, and Hal Foster, among others. She maps the tension between radical dialectics and left nihilism and assesses the interpretation and internalization of negation in art theory. Chapters confront the claim that exchange and equivalence have subsumed the use value of cultural objects—and with it critical distance— and interrogate the proposition of completed nihilism and the metropolis put forward in the politics of Italian operaismo. Day covers the debates on symbol and allegory waged within the context of 1980s art and their relation to the writings of Walter Benjamin and Paul de Man. She also examines common conceptions of mediation, totality, negation, and the politics of anticipation. A necessary unsettling of received wisdoms, _Dialectical Passions_ recasts emancipatory reflection in aesthetics, art, and architecture. (shrink)

ABSTRACTAt least in some dialogues, Plato has been thought to hold the so-called Two Worlds Theory, according to which there can be belief but not knowledge about sensibles, and knowledge but not belief about forms. The Phaedo is one such dialogue. In this paper, I explore some key passages that might be thought to support TW, and ask whether they in fact do so. I also consider the related issue of whether the Phaedo argues that, if knowledge is possible at (...) all, we can have it only when discarnate. (shrink)