Background: Individuals with psychopathic traits demonstrate an attenuated emotional response to aversive stimuli. However, recent evidence suggests heterogeneity in emotional reactivity among individuals with psychopathic or callous-unemotional (CU) traits, the emotional detachment dimension of psychopathy. We hypothesize that primary variants of psychopathy will respond with blunted affect to negatively valenced stimuli, whereas individuals marked with histories of childhood trauma/maltreatment exposure, known as secondary variants, will display heightened emotional reactivity. To test this hypothesis, the present study examined fear-potentiated startle between psychopathy (...) variants while viewing aversive, pleasant, and neutral scenes. Method: 238 incarcerated adolescent (M age = 16.8, SD = 1.11 years) boys completed a picture-startle paradigm and self-report questionnaires assessing CU traits, antisocial-aggressive behavior, and maltreatment. Results: Latent profile analyses identified four classes; primary variants (high CU traits, high aggression, low maltreatment; n = 46), secondary variants (high CU traits, high aggression, high maltreatment; n = 42), and two nonpsychopathic groups differentiated on maltreatment experience (n = 148). Findings from an ANOVA comparing identified groups on startle amplitude difference scores (i.e., aversive-neutral) suggested a main effect for group, F(3,196)=8.91, p<.001, η2 = .12. Primary variants of juvenile psychopathy displayed reduced startle potentiation to aversive images (threat and victim scenes), whereas secondary variants distinguished by high levels of childhood maltreatment did not. Conclusions: Findings add to a rapidly growing body of literature supporting the possibility of multiple developmental pathways to psychopathy (i.e., equifinality), and extend it by finding support for divergent potential biomarkers between primary and secondary psychopathy variants. (shrink)

Recently, there has been increasing interest in methodological aspects of advanced imaging, including the role of guidelines, recommendations, and experts’ consensus, the practice of self-referral, and the risk of diagnostic procedure overuse. In a recent Delphi study of the European Association for Nuclear Medicine (EANM), panelists were asked to give their opinion on 47 scientific questions about imaging in prostate cancer. Nine additional questions exploring the experts’ attitudes and opinions relating to the procedure of consensus building itself were also included. (...) The purpose was to provide insights into the mechanism of recommendation choice and consensus building as seen from the experts’ point of view. Results: Regarding the factors likely to influence the willingness to refer a patient for imaging, the most voted were incorporation into guidelines and data from scientific literature, while personal experience and personal relationship were chosen by a small minority. Regarding the recommendations more relevant to prescribe an imaging procedure, it resulted the incorporation into guidelines promoted by scientific societies (59% of votes); these guidelines also resulted the more trusted. With respect to patients’ preferences considered when prescribing an imaging procedure, the most voted was accuracy, resulted more important than easy access and time to access to the procedure. The majority of the experts expressed the opinion that there is a scarce use of imaging procedures in prostate cancer. With respect to the most relevant factor to build consensus, it resulted the transparency of the process (52% of votes), followed by multidisciplinarity of contributors. The main obstacle to incorporation of modern imaging procedures into guidelines resulted the lack of primary literature on clinical impact. Conclusions: Firstly, the panelists portray themselves as having Evidence-Based Medicine oriented and scientifically inclined attitudes and preferences. Secondly, guidelines and recommendations from scientific societies, especially clinical ones, are positively taken into account as factors influencing decisions, but panelists tend to consider their own appraisal of the scientific literature as more relevant. Thirdly, in respect of overuse, panelists do not think that advanced diagnostic procedures are overutilized in the specific case of Prostate Cancer, but rather they are underutilized. (shrink)

This chapter addresses concerns that pragmatic encroachers are committed to problematic knowledge variance. It first replies to Charity Anderson and John Hawthorne’s new putative problem cases, which purport to show that pragmatic encroachment is committed to problematic variations in knowledge depending on what choices are available to the potential knower. It argues that the new cases do not provide any new reasons to be concerned about the pragmatic encroacher’s commitment to knowledge-variance. The chapter further argues that concerns about knowledge-variance are (...) not limited to the pragmatic encroacher, but come up for traditional purist invariantism as well. (shrink)

This paper presents duality results between categories of neighbourhood frames for modal logic and categories of modal algebras (i.e. Boolean algebras with an additional unary operation). These results extend results of Goldblatt and Thomason about categories of relational frames for modal logic.

Explores Aristotle's theory of the causes that give rise to stasis ('civic disorder'), and provides an original and systematic account of his understanding of political justice and friendship.

In Neither Physics Nor Chemistry, Kostas Gavroglu and Ana Simoes examine the evolution of quantum chemistry into an autonomous discipline, tracing its development from the publication of early papers in the 1920s to the dramatic changes ...

What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our (...) life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals. (shrink)

Psychologists and philosophers agree that personal narratives are a central component of one’s identity. The concept of narrative self has been proposed to capture this aspect of selfhood. In recent times, it has been a matter of debate how the narrative self relates to the embodied and experiential dimension of the self. In this debate, the role attributed to inner speech is that of constructing and maintaining personal narratives. Indeed, evidence suggests that inner speech episodes are involved in self-reflection and (...) autobiographical reasoning. That is, previous works have focused mostly, if not solely, on the role of inner speech for narrative self-understanding. However, inner speech is also involved in enacting personal narratives. In such cases, the content of the inner speech episodes is not in the service of the construction of narratives, rather it implies the identification with the character of the personal narratives. I introduce two instances of the use of inner speech for narrative self-enactment: positive self-talk and stereotype threat. I conclude by considering the implications of the examples introduced for the debate regarding the relation between the narrative and the embodied dimensions of selfhood. (shrink)

This paper presents an emerging aspect of intentionality through recent Artificial Intelligence (AI) developments in art and design. Our main thesis is that, if we focus just on the outcome of the artistic process, the intentionality of the artist does not have any relevance. Intention is measured as a result of actions regardless of whether they are human-based or not as long as there is an esthetical value intersubjectively acknowledged. In other words, what matters is the ‘intentio’ embedded in the (...) work of art (the output) rather than the ‘intendere’ (the process). By considering the former aspect, intentionality becomes free of human intervention, therefore 'unintentional'. This thesis is supported through a range of examples related to AI in general and AI art in particular. However, in the case of a self-driving vehicle, the macro-goal of the system is fixed by humans, even though the AI system itself will take care of decomposing the macro-goal into a set of micro-goals and take the corresponding decisions. In the case of art, the system does not need to have any exterior goal to the extent that art is pure freedom of expression, as many philosophers have acknowledged. In this sense, the decisions of any AI system generating art or design are independent of humans and must be judged only on the ground of the final outcome. A work of art will be judged ‘artistic’ to the extent that humans will recognize an artistic intent in the work itself. In particular, the introduction of random processes makes an AI-generated artwork fully independent of human creativity. (shrink)

I propose an analysis of deception as the activity of intentionally misleading other agents’ hypothetical inferences. Understanding deception in this way has the advantages of clarifying the epistemological and cognitive dynamics involved in deception. Indeed, if deception can be framed as the intentional manipulation of others’ hypothetical inferences so that they will accept the false or disadvantageous hypotheses, then a better understanding of the epistemological and cognitive dynamics involved in deception will emerge by clarifying how abduction works. Tracing it back (...) to Peirce’s analysis, I will focus on recent perspectives on abduction, which stress the inherent strategic character of abductive cognition and offer a realistic description of the reasoners’ capabilities and their scant resources, both internal (computational power) and external (time and information available). To support and substantiate my thesis, I will examine psychological analyses of military deception. I will conclude by remarking the advantages of the thesis here presented to better understand the epistemological dynamics of deception and by highlighting the questions it leaves open for further investigations. (shrink)

Il mondo contemporaneo è caratterizzato - in un modo impensabile anche solo qualche decennio fa - dall'assoluta preminenza dell'economia nella gestione istituzionale degli uomini come nel loro orizzonte soggettivo. Se il pensiero economico nella sua veste di "scienza" costituisce il sapere indiscutibile a cui fanno appello le istituzioni odierne - per esempio, l'Unione Europea - la ricerca, a cui appartiene questo libro, delle logiche e degli orizzonti religiosi, teologici e filosofico-morali alle origini, ma ancora sotterraneamente vitali, di tale "scienza" e (...) - quindi - del mondo contemporaneo contribuisce a comprendere criticamente il presente, un compito oggi tanto inattuale quanto necessario. (shrink)

The atomistic paradigm of high energy physics cannot anymore be dismissed because the proposed elementary particles are too many or because it is not possible to observe quarks in an isolated manner. The developments in particle physics have brought about radical changes to our notions of simplicity and observability, and in this paper we elaborate on these changes. It is as a result of these changes that the present situation in elementary particle physics justifies our claim that we have indeed (...) reached a level of explanation where the constituent particles used for the explanation of the various phenomena considered to be delineating a particular level in the descriptive framework of the physical phenomena and a specific stratum in the organization of nature, can be regarded as elementary. (shrink)

The identification of a reference standard is a major problem in diagnostic imaging. This comment invites reflection on the notion by illustrating three philosophical approaches to truth and evidence.

How happy it is to recall Imre Lakatos. Now, fifteen years after his death, his intelligence, wit, generosity are vivid. In the Preface to the book of Essays in Memory of Imre Lakatos, the editors wrote:... Lakatos was a man in search of rationality in all of its forms. He thought he had found it in the historical development of scientific knowledge, yet he also saw rationality endangered everywhere. To honor Lakatos is to honor his sharp and aggressive criticism as (...) well as his humane warmth and his quick wit. He was a person to love and to struggle with. The book before us carries old and new friends of that Lakatosian spirit further into the issues which he wanted to investigate. That the new friends include a dozen scientific, historical and philosophical scholars from Greece would have pleased Lakatos very much, and with an essay from China, he would have smiled all the more. But the key lies in the quality of these papers, and in the imaginative organization of the conference at Thessaloniki in summer 1986 which worked so well. (shrink)

Current books on evolutionary theory all seem to take for granted the fact that students find evolution easy to understand when actually, from a psychological perspective, it is a rather counterintuitive idea. Evolutionary theory, like all scientific theories, is a means to understanding the natural world. Understanding Evolution is intended for undergraduate students in the life sciences, biology teachers or anyone wanting a basic introduction to evolutionary theory. Covering core concepts and the structure of evolutionary explanations, it clarifies both what (...) evolution is about and why so many people find it difficult to grasp. The book provides an introduction to the major concepts and conceptual obstacles to understanding evolution, including the development of Darwin's theory, and a detailed presentation of the most important evolutionary concepts. Bridging the gap between the concepts and conceptual obstacles, Understanding Evolution presents evolutionary theory with a clarity and vision students will quickly appreciate. (shrink)

Models for the Lambek calculus of syntactic categories surveyed here are based on frames that are in principle of the same type as Kripke frames for intuitionistic logic. These models are extracted from the literature on models for relevant logics, in particular the ternary relationed models introduced in the early seventies. The purpose of this brief survey is to locate some open completeness problems for variants of the Lambek calculus in the context of completeness results based on various types of (...) ternary relational models. (shrink)

Debates in 4E and scaffolded cognition have been centered on cases in which human cognitive or affective capacities are enhanced through technology. Recently some authors have noted that this may not always be the case: the technologies and environment around us can negatively impact cognitive and affective abilities. In the first part, I elaborate on this change of perspective in the debate. In the second part, I discuss a case of technology scaffolding maladaptive psychological processes. More in detail, I will (...) focus on the role of smartphones in scaffolding ruminative processes. To illustrate this claim, I introduce four core features of rumination and discuss how they may be supported by problematic smartphone use in light of existing evidence. (shrink)

This concise, accessible and engaging collection debunks the myths and corrects the falsehoods surrounding one of the most famous scientific figures in history - Charles Darwin. Leading scholars examine his life and work to set the historical record straight, and to draw conclusions about the very nature of science itself.

Who should rule? -- The exercise of power : liberty -- Politics as activity : participation, deliberation, conflict -- The end of politics : the good life, a better world.

The purpose of this paper is to connect the proof theory and the model theory of a family of propositional logics weaker than Heyting's. This family includes systems analogous to the Lambek calculus of syntactic categories, systems of relevant logic, systems related toBCK algebras, and, finally, Johansson's and Heyting's logic. First, sequent-systems are given for these logics, and cut-elimination results are proved. In these sequent-systems the rules for the logical operations are never changed: all changes are made in the structural (...) rules. Next, Hubert-style formulations are given for these logics, and algebraic completeness results are demonstrated with respect to residuated lattice-ordered groupoids. Finally, model structures related to relevant model structures (of Urquhart, Fine, Routley, Meyer, and Maksimova) are given for our logics. These model structures are based on groupoids parallel to the sequent-systems. This paper lays the ground for a kind of correspondence theory for axioms of logics with implication weaker than Heyting's, a correspondence theory analogous to the correspondence theory for modal axioms of normal modal logics.The first part of the paper, which follows, contains the first two sections, which deal with sequent-systems and Hubert-formulations. The second part, due to appear in the next issue of this journal, will contain the third section, which deals with groupoid models. (shrink)

Proof theory and category theory were first drawn together by Lambek some 30 years ago but, until now, the most fundamental notions of category theory have not been explained systematically in terms of proof theory. Here it is shown that these notions, in particular the notion of adjunction, can be formulated in such as way as to be characterised by composition elimination. Among the benefits of these composition-free formulations are syntactical and simple model-theoretical, geometrical decision procedures for the commuting of (...) diagrams of arrows. Composition elimination, in the form of Gentzen's cut elimination, takes in categories, and techniques inspired by Gentzen are shown to work even better in a purely categorical context than in logic. An acquaintance with the basic ideas of general proof theory is relied on only for the sake of motivation, however, and the treatment of matters related to categories is also in general self contained. Besides familiar topics, presented in a novel, simple way, the monograph also contains new results. It can be used as an introductory text in categorical proof theory. (shrink)

Kripke-style models with two accessibility relations, one intuitionistic and the other modal, are given for analogues of the modal systemK based on Heyting's prepositional logic. It is shown that these two relations can combine with each other in various ways. Soundness and completeness are proved for systems with only the necessity operator, or only the possibility operator, or both. Embeddings in modal systems with several modal operators, based on classical propositional logic, are also considered. This paper lays the ground for (...) an investigation of intuitionistic analogues of systems stronger thanK. A brief survey is given of the existing literature on intuitionistic modal logic. (shrink)

Science appeared in modern Greece in the first decades after its establishment as a sovereign state in 1828. The University of Athens, the Royal Observatory, the Botanical Garden, and the Natural History Museum were quickly established as spaces of scientific activity. Greek scientists were enthusiastic participants in the emerging Greek public sphere, often not only as science experts, but also as poets, intellectuals and political personae. In a space whose cultural, intellectual and historical boundaries were still being negotiated, the choice (...) of language was not a given but a pressing, sensitive national desideratum. This article examines how Greek scientists used languages to communicate with their peers and with their publics, how they handled terminology and nomenclature, and how the issues surrounding the Greek language in particular affected their practice as scientists. The article aims to show that, in nineteenth-century Greece, languages were not passive, neutral vehicles of communication, but rather integral (though tacit) components of the practice of science. (shrink)

The purpose of this work is to present Gentzen-style formulations of S5 and S4 based on sequents of higher levels. Sequents of level 1 are like ordinary sequents, sequents of level 1 have collections of sequents of level 1 on the left and right of the turnstile, etc. Rules for modal constants involve sequents of level 2, whereas rules for customary logical constants of first-order logic with identity involve only sequents of level 1. A restriction on Thinning on the right (...) of level 2, which when applied to Thinning on the right of level 1 produces intuitionistic out of classical logic (without changing anything else), produces S4 out of S5 (without changing anything else). This characterization of modal constants with sequents of level 2 is unique in the following sense. If constants which differ only graphically are given a formally identical characterization, they can be shown inter-replaceable (not only uniformly) with the original constants salva provability. Customary characterizations of modal constants with sequents of level 1, as well as characterizations in Hilbert-style axiomatizations, are not unique in this sense. This parallels the case with implication, which is not uniquely characterized in Hilbert-style axiomatizations, but can be uniquely characterized with sequents of level 1. These results bear upon theories of philosophical logic which attempt to characterize logical constants syntactically. They also provide an illustration of how alternative logics differ only in their structural rules, whereas their rules for logical constants are identical. (shrink)