In this article, we describe an ontology aimed at the representation of the relevant entities and relations in the philosophical world. We will guide the reader through our modeling choices, so to highlight the ontology’s practical purpose: to enable an annotation of philosophical resources which is capable of supporting pedagogical navigation mechanisms. The ontology covers all the aspects of philosophy, thus including characterizations of entities such as people, events, documents, and ideas. In particular, here we will present a detailed exposition (...) of the entities belonging to the idea branch of the ontology, for they have a crucial role in the world of philosophy. Moreover, as an example of the type of applications made possible by the ontology we will introduce PhiloSurfical, a prototype tool we created to navigate contextually a classic work in twentieth century philosophy, Wittgenstein’s Tractatus Logico-Philosophicus. We discuss the potential usage of such navigation mechanisms in educational and scholarly contexts, which aim to enhance the learning process through the serendipitous discovery of relevant resources. (shrink)

The tumor microenvironment (TME) plays a pivotal role in the behavior and development of solid tumors as well as shaping the immune response against them. As the tumor cells proliferate, the space they occupy and their physical interactions with the surrounding tissue increases. The growing tumor tissue becomes a complex dynamic structure, containing connective tissue, vascular structures, and extracellular matrix (ECM) that facilitates stimulation, oxygenation, and nutrition, necessary for its fast growth. Mechanical cues such as stiffness, solid stress, interstitial fluid (...) pressure (IFP), matrix density, and microarchitecture influence cellular functions and ultimately tumor progression and metastasis. In this fight, our body is equipped with T cells as its spearhead against tumors. However, the altered biochemical and mechanical environment of the tumor niche affects T cell efficacy and leads to their exhaustion. Understanding the mechanobiological properties of the TME and their effects on T cells is key for developing novel adoptive tumor immunotherapies. (shrink)

The focus of this paper is on two attempts Sainati made to renew neo-idealistic themes by means of suggestions drawn from the famous Goedel’s Incompleteness Theorems of 1931. Sainati’s remarks on the relationship between «logo astratto » and «logo concreto» are here pursued by reference to some of Goedel’s unpublished texts.

Papers from the 1994 meeting represent a broad review of contemporary experimental work on quantum phenomena, emphasizing state-of-the-art experimental science. Useful as an introductory manual for young researchers, the volume addresses topics that include: experiments with single and ultracold ato.

Rédigé par des spécialistes internationaux, cet ouvrage a pour but de guider le lecteur à travers les écrits d’Aristote. Les auteurs de ces études ont cherché avant tout à faire comprendre des questions : celles que se posait le philosophe et celles que l’on peut se poser à propos de ses thèses et de ses arguments. Ils examinent chacun des principaux aspects de l’œuvre d’Aristote à travers des contributions portant sur toute l’étendue de ses recherches. Ils s’efforcent de présenter, dans (...) leur contexte historique, le vocabulaire et les concepts en montrant leur caractère innovant, et parfois incertain et risqué, qui ont contribué à l’influence des écrits d’Aristote sur la philosophie et sur toute l’histoire intellectuelle de l’Occident. (shrink)

After a short summary of the interpretation of Thomas Aquinas’ conception of being given by E. Gilson, according which the actus essendi is existence, the article sets out the criticisms addressed to this conception by P.T. Geach and A. Kenny, showing that they converge with the criticism developed by the author himself in an article of 1979 on Aristotle. In the author’s view, the best reply to this criticism given by the Thomists is the reply of S.L. Brocks, who has (...) shown that the actus essendi is the perfect way of being which belongs only to God. The author shows that this conception is confirmed by some passages of Thomas’ De ente et essentia. (shrink)