Fertility clinicians participate in non-sexual reproductive projects by providing assisted reproductive technology (ART) to those hoping to reproduce, in support of their reproductive goals. In most countries where ART is available, the state regulates ART as a form of medical treatment. The predominant position in the reproductive rights literature frames the clinician’s role as medical technician, and the state as a third party with limited rights to interfere. These roles broadly align with established functions of clinician and state in Western (...) liberal democracies, where doctors have duties to provide safe, beneficial and legal healthcare to all who seek it. Recognised state responsibilities include safeguarding equitable access to medical services and protecting and promoting reproductive liberty.I argue against this normative moral framing of clinician and state involvement in non-sexual reproduction, suggesting that clinician and state join the non-sexual reproductive project at the point of triggering conception. Begetting a child is more than just the provision and regulation of healthcare; it generates rights and confers responsibilities on all who join this morally significant project. All who collaborate have the right to join or refuse to join the project. I suggest this is intuitively understood in the sexual realm, but not in the non-sexual realm. My key substantive claim is that non-sexual reproduction is a pluralist pursuit that morally implicates more than the genetic and gestational contributors. I find that while the moral basis of a clinician or the state’s right to refuse to join the ART project is the same as for those providing gestational or genetic input, the reasons that morally underpin their refusal differs. (shrink)

From renowned classicist Edith Hall, ARISTOTLE'S WAY is an examination of one of history's greatest philosophers, showing us how to lead happy, fulfilled, and meaningful lives Aristotle was the first philosopher to inquire into subjective happiness, and he understood its essence better and more clearly than anyone since. According to Aristotle, happiness is not about well-being, but instead a lasting state of contentment, which should be the ultimate goal of human life. We become happy through finding a purpose, realizing (...) our potential, and modifying our behavior to become the best version of ourselves. With these objectives in mind, Aristotle developed a humane program for becoming a happy person, which has stood the test of time, comprising much of what today we associate with the good life: meaning, creativity, and positivity. Most importantly, Aristotle understood happiness as available to the vast majority us, but only, crucially, if we decide to apply ourselves to its creation--and he led by example. As Hall writes, "If you believe that the goal of human life is to maximize happiness, then you are a budding Aristotelian." In expert yet vibrant modern language, Hall lays out the crux of Aristotle's thinking, mixing affecting autobiographical anecdotes with a deep wealth of classical learning. For Hall, whose own life has been greatly improved by her understanding of Aristotle, this is an intensely personal subject. She distills his ancient wisdom into ten practical and universal lessons to help us confront life's difficult and crucial moments, summarizing a lifetime of the most rarefied and brilliant scholarship. (shrink)

While the definitions employed by different governmental agencies and scientific societies differ somewhat, the term “nanotechnology” is generally understood to refer to the manufacturing, characterization, and use of man-made devices with dimensions on the order of 1-100 nanometers. Devices that comprise a fundamental functional element that is nanotechnological are also frequently comprised within nanotechnology, as are manufactured objects with dimensions less than one micrometer. The differences in definition lead to occasional paradoxes, such as the fact that the most widely used (...) nanodrug is labeled a “nanopharmaceutical” by governments of European countries, Canada, and Australia, but it is not a nanotechnology for the U.S. Food and Drug Administration. It is also common in scientific domains to restrict the term “nanotechnology” to objects that possess special, “emerging” properties that only arise because of their nanoscale dimension. (shrink)

The ethics of physical restraint in the Emergency Department has always been an emotive and controversial issue. Recently a vanguard of advocacy groups and regulatory agencies have...

Background:Altering components of ecological momentary assessment (EMA) measures to better suit the purposes of individual studies is a common and oftentimes necessary step. Though the inherent flexibility in EMA has its benefits, no resource exists to provide an overview of the variability in how convergent constructs and symptoms have been assessed in the past. The present study fills that gap by examining EMA measurement design for mood and anxiety symptomatology.Methods:Various search engines were used to identify 234 relevant studies. Items administered, (...) data collection schedules (i.e., beeps per day), response scales (i.e., Likert), data collection platforms (i.e., apps), and psychometric properties (i.e., reliability) were extracted.Results:Study designs varied greatly in all aspects across the identified papers. Over 4,600 extracted items were qualitatively analyzed, resulting in the identification of 12 themes. The most EMA items focused on affect, with categories such as “happiness” and “tension” appearing most frequently. We provide all of our data extraction in the format of an open-source database.Limitations:Despite our best attempts to include as much of the relevant literature as possible, this review and the accompanying database are not exhaustive, but can easily be built upon to include other, newer studies.Conclusions:The fact that the affect theme featured both positive and negative emotional constructs highlights the dichotomous focus on valence and affect within the literature surrounding anxious and depressive symptomatology. We hope that our database will act as a helpful design decision-making resource for researchers studying this kind of symptomatology in the future.Systematic Review Registration:PROSPERO (CRD42019139409). (shrink)

Recent enthusiasm for grounding often begins by observing that inquiry in metaphysics (and other areas) features a distinctive species of noncausal explanation. Having labeled this species “grounding explanation,” it’s a short step to the conclusion that we need a philosophical theory of grounding itself: an allegedly fundamental relation of metaphysical dependency between facts, such that a “grounding explanation” of some fact succeeds by providing information about what “grounds” that fact. This short step is hasty. For another live option is to (...) accept that grounding explanation is a legitimate form of explanation, but to give it a thoroughly epistemic treatment, one that does not see it as involving any sort of special metaphysical relationship or structure at all. This paper sketches such a treatment, drawing inspiration from reflections on explanatory structure in mathematics. (shrink)

Partiendo de mi exploración previa sobre el papel de la danza en la obra del filósofo político francés contemporáneo Jacques Rancière en su libro Aisthesis, publicado por primera vez en francés en 2011, el presente ensayo se centra en otro libro publicado originalmente en el mismo año, Las distancias del cine. Después de haber establecido previamente que el núcleo del método filosófico de Rancière implica un análisis de homónimos filosóficos en parejas conceptuales figurativas de baile, comienzo aplicando ese método al (...) primer capítulo de Distancias titulado “El vértigo cinematográfico: Hitchcock-Vertov y vuelta”. Allí identifico dos series de tales parejas de baile de la siguiente manera: la caída vertiginosa capitalista controlada por la imagen de Hitchcock y el baile equilibrado y comunista de Vertov que iguala los movimientos. Luego, critico la marginalización implícita de las mujeres y los cuerpos femeninos en las películas y el capítulo, incluyendo a la mejor amiga y ex prometida del protagonista de Hitchcock, así como a las cosmetólogas y operadoras de centralita de Vertov. Finalmente, ofrezco una corrección basada en la vida protofeminista de mi abuela, una vez cosmetóloga, operadora de centralita y modelo amateur de Glamour Shots, mi abuela Louise Nunnelley o “Mamaw”. Estos son la base material no reconocida de la filosofía democrática radical de Rancière, las bailarinas específicamente encarnadas y posicionadas que siguen perdiéndose en su baile figurativo. (shrink)

Public participation and survivor research in mental health are widely recognized as vital to the field. At the same time, contributions of patient collaborators can present unique challenges to determining authorship. Using an unresolved dispute around research contributions to the American Psychiatric Association’s Psychiatric Services journal, authorship and contribution are addressed. Recommendations are suggested to prevent dilemmas and achieve responsible research credit inclusion, especially among researchers with different backgrounds and asymmetric power relations. Researchers and publishers can prepare proactively for conflict (...) through consensus on authorship criteria, prior agreements around author inclusion, arrangement for third party dispute resolution, transparency in communication and contracts, notification to prospective publications of pending disputes, a contributor-guarantor model of contribution, journal editor “expressions of concern” when authorship disputes go unresolved, and expectation of conflict as generative. (shrink)

This paper poses a dilemma for applying the category of substance given Kant's different conceptions of substance in the Critique of Pure Reason. Briefly stated, if the category of substance applies to an omnipresent and sempiternal substance, then although this would ensure that all experiences of empirical objects take place in a common spatiotemporal framework, one could not individuate these empirical objects and experience their alterations. If the category of substance applies to ordinary empirical objects, however, then although one could (...) individuate these substances and experience their alterations, the category would not pick out a common spatiotemporal framework for these experiences. I will argue that this dilemma can be overcome by examining the development of Kant's conception of substance in his final work, the Opus postumum. (shrink)

To explain the menstrual cycle and menopause, human biologists during the past several decades have developed new models of the evolutionary origins and maintenance of female reproductive patterns that address both ultimate and proximate causation. Hypotheses proposed for these processes generally offer explanations for menstruation or for menopause, but not for both; ultimately, these explanations must be integrated. Reviewing current explanations, this paper offers an energetics-based evolutionary rationale compatible with past adaptations of Homo sapiens and with ecological patterns in small-scale, (...) preindustrial social systems in which food resources vary and sometimes are scarce. (shrink)

MS. 124 in the library of St. John Baptist College, Oxford, is a quarto of 154 pages, written in two or more hands of the fifteenth century. Its provenance is unknown, and, as it has been carefully and ruthlessly rebound at some time in the nineteenth century, it is impossible to derive any information from the binding. After an unusually elabbrate alphabetical index it bears on folio 11 an inscription in a seventeenth-century hand as follows: ‘Libellus Thomae de Walsingham De (...) generacione naturaque deorum simul cum interpretatione Ouidii Metamorphoseon Simoni Priori Sancti Albani dedicatus.’. (shrink)

The stringent demands of discipleship were not, therefore, presented by Jesus as a universally applicable ethic of heroic proportions—and still less as an esoteric avenue to salvation—but only as the preconditions for the work of the Kingdom to be done.