BackgroundAs the use of AI becomes more pervasive, and computerised systems are used in clinical decision-making, the role of trust in, and the trustworthiness of, AI tools will need to be addressed. Using the case of computational phenotyping to support the diagnosis of rare disease in dysmorphology, this paper explores under what conditions we could place trust in medical AI tools, which employ machine learning.MethodsSemi-structured qualitative interviews with stakeholders who design and/or work with computational phenotyping systems. The method of constant (...) comparison was used to analyse the interview data.ResultsInterviewees emphasized the importance of establishing trust in the use of CP technology in identifying rare diseases. Trust was formulated in two interrelated ways in these data. First, interviewees talked about the importance of using CP tools within the context of a trust relationship; arguing that patients will need to trust clinicians who use AI tools and that clinicians will need to trust AI developers, if they are to adopt this technology. Second, they described a need to establish trust in the technology itself, or in the knowledge it provides—epistemic trust. Interviewees suggested CP tools used for the diagnosis of rare diseases might be perceived as more trustworthy if the user is able to vouchsafe for the technology’s reliability and accuracy and the person using/developing them is trusted.ConclusionThis study suggests we need to take deliberate and meticulous steps to design reliable or confidence-worthy AI systems for use in healthcare. In addition, we need to devise reliable or confidence-worthy processes that would give rise to reliable systems; these could take the form of RCTs and/or systems of accountability transparency and responsibility that would signify the epistemic trustworthiness of these tools. words 294. (shrink)

In this introduction to Nehemiah Grew's seminal 17th-century publication The Anatomy of Plants (1682), we discuss the various influences on and impacts of Grew's innovative approach to studying plant life. We offer a review of the current literature on Grew and argue for the importance of his work in its contribution to fields ranging from microscopy to agriculture and from comparative anatomy to scientific illustration. The articles included in this special issue on “The Making of The Anatomy of Plants” are (...) also introduced. We make a case for Grew as a figure of great interest and relevance in our contemporary moment; as plant studies have taken hold in the humanities, historical narratives in the history of science are expanding to include more of the life sciences—a field that, as we show, Grew actively promoted and participated in throughout his tenure at the Royal Society. (shrink)

I takt med at det naturhistoriske vidensideal i løbet af 1600-tallet i højere grad blev knyttet til observationer, eksperimenter og andre former for direkte kontakt med naturens fænomener, fremkom den naturhistoriske ekspert som en vigtig videnskabelig aktør. I denne artikel viser jeg, hvordan den hollandske mikroskopist Antoni van Leeuwenhoek indgik som ekspert i to umiddelbart væsensforskellige netværk, nemlig det engelske videnskabelige selskab Royal Society og det Nederlandske Ostindiske Handelskompagni (VOC). Hvor Royal Society havde som sit erklærede formål at skabe ny, (...) eksperimentel viden om naturen, var VOC’s formål at tjene penge til sin bestyrelse på baggrund af aggressiv ekspansion af koloniale aktiviteter i Sydøstasien. Leeuwenhoeks evner indenfor mikroskopi gjorde, at Royal Societymedlemmerne sendte ham observationsopgaver og endda objekter, som han kunne undersøge gennem sine mikroskoper. På samme måde fik Leeuwenhoek adgang til VOC-officerers kister med koloniale frø, og han blev bedt om at undersøge deres krydderilagre med det formål at skabe bedre viden om de koloniale materialers reproduktionscyklusser. Ved at studere Leeuwenhoeks rolle som ekspert i disse to netværk argumenterer jeg for en porøs distinktion mellem kommerciel og videnskabelig aktivitet. (shrink)

Most research on mind-wandering has characterized it as a mental state with contents that are task unrelated or stimulus independent. However, the dynamics of mind-wandering—how mental states change over time—have remained largely neglected. Here, we introduce a dynamic framework for understanding mind-wandering and its relationship to the recruitment of large-scale brain networks. We propose that mind-wandering is best understood as a member of a family of spontaneous-thought phenomena that also includes creative thought and dreaming. This dynamic framework can shed new (...) light on mental disorders that are marked by alterations in spontaneous thought, including depression, anxiety and attention deficit hyperactivity disorder. (shrink)

The idea of an inevitable conflict between science and religion leading to relentless hostility between the two emerged in the nineteenth century and has become a powerful narrative of modernity. Most historians of science trace the origins of the so-called ‘conflict thesis’ to the English-speaking world, more precisely to scientist-historian John William Draper and literary scholar Andrew Dickson White. Their books on the history of scientific-religious conflict turned into bestsellers. Yet, if we look beyond the Anglo-American world, the conflict thesis (...) appears in new historical settings. This paper argues that the science vs. religion narrative flourished already in Germany before Draper and White announced the warfare between science and religion in England and the USA. Focusing on Germany, we aim to show that the conflict thesis emerged in a polycentric process shaped by various political, cultural, and social struggles. It became a rhetorical weapon for liberal scientists in Germany to oppose Ultramontanism and, at the same time, to discredit their rivals as unscientific, fanatic, or even as ‘henchmen’ of the Pope. Our paper makes a case for a decentred approach to the history of the conflict thesis, which brings to the fore specific political and cultural tensions shaping this narrative in the nineteenth century. (shrink)

Draʿ Abu El-Naga I: Eindrücke Grabkegel als Elemente thebanischer Grabarchitektur. By Elisabeth Kruck. Deutsches Archäologisches Institut, Abteilung Kairo, Archäologische Veröffentlichungen, vol. 124. Wiesbaden: Harrassowitz Verlag, 2012. Pp. 167, 10 plates. €98.

Studies on the Middle Kingdom: In Memory of Detlef Franke. Edited by Hans-Werner Fischer- Elfert and Richard B. Parkinson. Philippika, vol. 41. Wiesbaden: Harrassowitz Verlag, 2013. Pp. 268, 8 pls. €58.

In August of 1971, President Nixon announced that the United States was “closing the gold window,” bringing an end to the postwar system of international exchange rate stability and precipitating a period of significant uncertainty and transformation in global institutions. Although this critical historical episode is important for an understanding of historical “neoliberalism” and institutional change, modern sociological perspectives have scarcely been applied to it. The present analysis uses archival data to show that closing the gold window was never the (...) goal or preferred strategy of the Nixon administration, which had spent years preparing much more modest reforms. Nevertheless, US policymakers took this unilateral action as a contingency plan to achieve a short-term goal, knowing that it would dramatically change the functioning of the international economy. Surprisingly, the autonomous structure of the IMF did not channel US initiatives toward gradual evolution but rather helped determine a radical change in strategy. (shrink)

Is theistic evolution (TE) a philosophically tenable position? Leidenhag argues in his article “The Blurred Line between Theistic Evolution and Intelligent Design” that it is not, since it, Leidenhag claims, espouses a view of divine action that he labels “natural divine causation” (NDC), which makes God explanatory redundant. That is, in so far as TE does not invoke God as an additional cause alongside natural causes, it is untenable. Theistic evolutionists should therefore “reject NDC and affirm a more robust notion (...) of divine agency.” However, this will, Leidenhag claims, have the effect that theistic evolutionists “will move their position significantly closer to Intelligent Design,” and so the line between TE and intelligent design is (or ought to be?) blurred. If successful, the criticism by Leidenhag would be bad news for theists who want to take science seriously and good news for those scientistic atheists according to whom there simply is no scientifically respectable way of combining theism and modern natural science in an overarching worldview. So, is TE stuck between a rock (of redundancy) and a hard place (of pseudo‐science)? No, at least not due to the criticism offered by Leidenhag—but maybe religious naturalism is? (shrink)

This article examines the early modern household's importance for producing experimental knowledge through an examination of the Halifax household of Margery and Henry Power. While Henry Power has been studied as a natural philosopher within the male-dominated intellectual circles of Cambridge and London, the epistemic labour of his wife, Margery Power, has hitherto been overlooked. From the 1650s, this couple worked in tandem to enhance their understanding of the vegetable world through various paper technologies, from books, paper slips and recipe (...) notebooks to Margery's drawing album and Henry's published Experimental Philosophy. Focusing on Margery's practice of hand-colouring flower books, her copied and original drawings of flowers and her experimental production of ink, we argue that Margery's sensibility towards colour was crucial to Henry's microscopic observations of plants. Even if Margery's sophisticated knowledge of plants never left the household, we argue that her contribution was nevertheless crucial to the observation and representation of plants within the community of experimental philosophy. In this way, our article highlights the importance of female artists within the history of scientific observation, the use of books and paperwork in the botanical disciplines, and the relationship between household science and experimental philosophy. (shrink)

In this essay, I study the contested role of magnification as an observational strategy in the generation theories of William Harvey and René Descartes. During the seventeenth century, the grounds under the discipline of anatomy were shifting as knowledge was increasingly based on autopsia and observation. Likewise, new theories of generation were established through observations of living beings in their smallest state. But the question formed: was it possible to extend vision all the way down to the first points of (...) life? Arguing that the potential of magnification hinged on the metaphysics of living matter, I show that Harvey did not consider observational focus on the material composition of blood and embryos to be conducive to knowledge of living bodies. To Harvey, generation was caused by immaterial, and thus in principle invisible, forces that could not be magnified. Descartes, on the other hand, believed that access to the subvisible scale of natural bodies was crucial to knowledge about their nature. This access could be granted through rational introspection, but possibly also through powerful microscopes. The essay thus ends with a reflection on the importance of Cartesian corpuscularianism for the emergence of microscopical anatomy in seventeenth-century England. (shrink)

ZusammenfassungPrinzipien und Dialektik. Zwei Arten Dialektik: Die Rückkehr zum «Anhypoteton» und das dialektisierende Denken. Beide Tendenzen sind gleichsam charakterisiert durch die Hervorhebung der Aktivität des Denkens. Das formale Denken aber sucht den Ursprung dieser Aktivität, während das dialektisierende Denken deren Anwendung feststellen will. Auf dem Suchen nach einem ersten Ursprung ist das formale Denken in Gefahr bloss formale Bedingungen zu erreichen. Das dialektisierende Denken will aber nur die Orientierung in dem gegebenen gegenwärtigen Suchen feststellen; dabei scheint es die Idee einer (...) ewigen Ordnung der Dinge preiszugcben, bleibt jedoch der menschlichen Situation treu. Beide Richtungen haben Sinn für entgegengesetzte Ziele. Möglichkeit einer anthropologischen Problematik. (shrink)

Nehemiah Grew is rightly lauded as one of the first and most sophisticated promoters of the discipline of plant anatomy—the observation and representation of the insides of plants. Overlooked so far, though, are his activities as a plant collector. In this paper, I reconstruct Grew's plant-collection practices from his first medical garden, through his incorporation of specimens from the Royal Society's repository, and to its expansion through his support of intercontinental plant-gathering missions. These activities gave Grew access both to fresh, (...) local plant samples, which he could observe again and again, as well as to foreign specimens that exhibited some of the more curious variations of nature. I argue that these different plant-collecting strategies reflected his overarching ambitions with his plant anatomy, which was to construct an idealised model of plant formation, generation, and growth. In order to do this, Grew pieced together his observations of individual specimens into one generalised model through the method of collation. While not offering concrete advice on how to grow plants more efficiently, I argue that Grew's idealised representation of the processes of plant life was offered as a framework for further botanical experimentation. (shrink)

Von Meroe bis Indien: Fremdvölkerlisten und nubische Gabenträger in den griechisch-römischen Tempeln. By Holger Kockelmann and Alexa Rickert. Studien zur spätägyptischen Religion, vol. 12. Wiesbaden: Harrassowitz Verlag, 2015. Pp. x + 357, 6 pls. €128.

review essay on Gaukroger, Collapse of Mechanism and Rise of Sensibility (OUP).

In this paper, I suggest that individuals who suffer trauma are often forced to reproduce that for material gain. After noting the key features of what I define as ‘performing trauma narratives’, I argue that the environments in which these narratives are told place undue epistemic burdens on the victims and fail to account for the differential understanding of listeners and the difficulties in conveying the descriptive and normative features with accuracy and integrity. I argue that this results in two (...) specific forms of epistemic injustice: structurally precarious testimonial injustice’ and binary hermeneutical injustice’. I go on to suggest that these epistemic burdens prevent the healing from the traumatic experience in virtue of causing victims to normatively dissociate from their traumatic experience causing victim’s to not appropriately integrate their memories into their conception of self. (shrink)

We take a logical approach to threshold models, used to study the diffusion of opinions, new technologies, infections, or behaviors in social networks. Threshold models consist of a network graph of agents connected by a social relationship and a threshold value which regulates the diffusion process. Agents adopt a new behavior/product/opinion when the proportion of their neighbors who have already adopted it meets the threshold. Under this diffusion policy, threshold models develop dynamically towards a guaranteed fixed point. We construct a (...) minimal dynamic propositional logic to describe the threshold dynamics and show that the logic is sound and complete. We then extend this framework with an epistemic dimension and investigate how information about more distant neighbors’ behavior allows agents to anticipate changes in behavior of their closer neighbors. Overall, our logical formalism captures the interplay between the epistemic and social dimensions in social networks. (shrink)

The Religious War of Science. Historical Argumentation in the Academic Speeches of Emil DuBois‐Reymond (1818–1896). Among the protagonists of the “laboratory revolution” (Cunningham/Williams) in 19th‐century physiology were the self‐proclaimed ‘organic physicists’ (“organische Physiker”), who shared a mechanistic conception of life processes. One of their key figures was the physiologist Emil DuBois‐Reymond (1818–1896) who not only excelled in the field of neuroscience but also became known, over the decades of his active career, as an orator at the Berlin Academy of Sciences (...) and Humanities. In his academic speeches, DuBois‐Reymond regularly commemorated heroes of the history of science. On closer inspection, these references went far beyond paying the usual homage to precursors: This paper argues that DuBois‐Reymond made use of episodes from the history of science as a means to legitimate his own reductionist research programme and, at the same time, decry idealistic natural philosophy and vitalistic positions. Drawing upon biblical rhetorics, DuBois‐Reymond systematically construed experimental physiology as the culmination of a teleological development, and, hence, organic physicists as the incarnation of scientific ‘redeemers’. According to him, the success of ‘organic physics’ displayed the peak of an inevitable development. (shrink)

Summary People with disabilities still show lower participation rates in mainstream sports clubs. Even when they are members of mainstream sports clubs, their participation is often limited to structural integration, while broader social integration including cultural and affective dimensions is only partially achieved. Thus, this study analyses the broader extent of social integration of members with disabilities in sports clubs, applying Esser’s model of social integration, which is comprised of four dimensions: culturation, interaction, identification, and placement. The article describes multiple (...) case studies conducted with this model on a sample of three mainstream clubs, including 14 members with disabilities. Results show overall high scores on the four dimensions, consequently pointing to effective social integration of members with disabilities. Moreover, the studies also reveal indications of factors that are relevant for social integration. This knowledge is helpful for clubs with regard to managing social integration strategies and practices. (shrink)

The author, an ordained Lutheran pastor, reflects upon his experiences as chaplain at a small hospital in southwestern Germany (Tropenklinik – Paul Lecher Krankenhaus, Tübingen). Besides its expertise in the treatment of tropical diseases this 100 + bed hospital serves as the referral hospital for terminally ill and dying patients from the local University hospitals and the surrounding area. The experiences at the bedside of such patients with various denominational and religious backgrounds challenged the chaplain to go beyond the confines (...) of any fixed theological system or counseling technique. They made him to discover three essentials as the very basis of such ministry, which he shares in this article. He identifies these as (1) the necessity to realize the situation sober mindedly, (2) the desire to become a companion, and (3) the venture of confident faith, where holding on to any genuine perspective of life is deemed ridiculous. (shrink)

This paper introduces a general logical framework for reasoning about diffusion processes within social networks. The new “Logic for Diffusion in Social Networks” is a dynamic extension of standard hybrid logic, allowing to model complex phenomena involving several properties of agents. We provide a complete axiomatization and a terminating and complete tableau system for this logic and show how to apply the framework to diffusion phenomena documented in social networks analysis.

Der ägyptische Tempel als ritueller Raum: Akten der internationalen Tagung, Haus der Heidelberger Akademie der Wissenschaften, 9.–12. Juni 2015. Edited by Stefan Baumann and Holger Kockelmann. Studien zur spätägyptischen Religion, vol. 17. Wiesbaden: Harrassowitz Verlag, 2017. Pp. xi + 584, 8 pls. €144.

A certain reading of Descartes, which we refer to as ‘the embodied Descartes’, is emerging from recent scholarship on L’Homme, in keeping with the interpretive trend which emphasizes Descartes’s identity as a natural philosopher. This reading complicates our understanding of Descartes’s philosophical project: far from strictly separating human minds from bodies, the embodied Descartes keeps them tightly integrated, while animal bodies behave in ways quite distinct from those of other pieces of extended substance. Here, we identify three categories of embodiment (...) in contemporary readings of Descartes’s physiology: bodily health and function, embodied reflex and memory, and embodied cognition. All present more or less strong versions of the embodied Descartes. Together, they constitute a compelling reading of a Cartesian natural philosophy that, if not expressly antidualist, is an awfully long way from the canonical picture. (shrink)

It is rather natural to suppose that what we mean when we say that an institutional organization has a moral duty is parallel to whatever it is that we mean when we say that an individual has a duty. I challenge this interpretation on the grounds that it assumes that institutional organizations possess those characteristics or abilities requisite for moral agency—an assumption which I argue is highly suspicious. Against such an interpretation, I argue that we have very good reasons to (...) suppose that the term 'has a duty' is used equivocally across individual and institutional contexts. In other words, the meaning of an institutional duty-claim is quite different than that of an individual duty-claim, so much so that we ought to recognize that institutional duty-claims are not really duty-claims at all. (shrink)

We take a logical approach to threshold models, used to study the diffusion of e.g. new technologies or behaviors in social net-works. In short, threshold models consist of a network graph of agents connected by a social relationship and a threshold to adopt a possibly cascading behavior. Agents adopt new behavior when the proportion of their neighbors who have already adopted it meets the threshold. Under this adoption policy, threshold models develop dynamically with a guaranteed fixed point. We construct a (...) minimal dynamic propositional logic to describe the threshold dynamics and show that the logic is sound and complete. We then extend this framework with an epistemic dimension and investigate how information about more distant neighbors’ behaviors allows agents to anticipate changes in behavior of their closer neighbors. It is shown that this epistemic prediction dynamics is equivalent to the non-epistemic threshold model dynamics if and only if agents know exactly their neighbors’ behavior. We further show results regarding fixed points and convergence speed,and provide a partial set of reduction laws, venues for further research, and graphical representations of the dynamics. (shrink)

ZusammenfassungPrinzipien und Dialektik. Zwei Arten Dialektik: Die Rückkehr zum «Anhypoteton» und das dialektisierende Denken. Beide Tendenzen sind gleichsam charakterisiert durch die Hervorhebung der Aktivität des Denkens. Das formale Denken aber sucht den Ursprung dieser Aktivität, während das dialektisierende Denken deren Anwendung feststellen will. Auf dem Suchen nach einem ersten Ursprung ist das formale Denken in Gefahr bloss formale Bedingungen zu erreichen. Das dialektisierende Denken will aber nur die Orientierung in dem gegebenen gegenwärtigen Suchen feststellen; dabei scheint es die Idee einer (...) ewigen Ordnung der Dinge preiszugcben, bleibt jedoch der menschlichen Situation treu. Beide Richtungen haben Sinn für entgegengesetzte Ziele. Möglichkeit einer anthropologischen Problematik. (shrink)

Zusammenfassung Für Sportvereine als Interessenorganisationen scheint die Rückbindung der Vereinsziele an die Mitgliederinteressen von zentraler Bedeutung zu sein. In der Vereinsrealität dürfte aber diese Rückbindung nur teilweise gewährleistet sein und folglich Ziel-Interessen-Divergenzen eher die Norm als die Ausnahme darstellen. Vor diesem Hintergrund stellt sich die Frage, welche Ursachen für Ziel-Interessen- Divergenzen verantwortlich zu machen sind und welche Auswirkungen sich daraus für die Vereine ergeben. Dieser Frage geht der vorliegende Beitrag nach, indem auf der Grundlage des akteurtheoretischen Mehr-Ebenen-Modells zur Analyse der (...) Entwicklung von Sportvereinen die struktur- und handlungsbedingten Ursachen und Auswirkungen von Divergenzen auf der Vereins- und Mitgliederebene beleuchtet werden. Mit Blick auf die Ursachen wurde der Einfluss der korporativen Vereinsstrukturen und der individuellen Handlungsorientierungen der Mitglieder auf Divergenzen untersucht. Die Befunde hierzu zeigen, dass Divergenzen einerseits durch einem zunehmenden Differenzierungs- und Hierarchisierungsgrad begünstigt werden und andererseits vor allem bei einer primären Verfolgung von Eigeninteressen der Mitglieder auftreten. Hinsichtlich der Auswirkungen wurden die individuellen Mitgliederreaktionen und die korporativen Vereinsreaktionen auf Divergenzen analysiert. Diesbezüglich zeigen die Befunde, dass sowohl die Mitglieder als auch die Vereinsführung überwiegend konstruktiv auf Divergenzen reagieren, so dass es vielen Vereinen offenbar relativ gut gelingt, Ziel-Interessen-Divergenzen bis zu einem gewissen Grad sowohl aushalten als auch aufarbeiten zu können. (shrink)

We study the logic of so-called lexicographic or priority merge for multi-agent plausibility models. We start with a systematic comparison between the logical behavior of priority merge and the more standard notion of pooling through intersection, used to define, for instance, distributed knowledge. We then provide a sound and complete axiomatization of the logic of priority merge, as well as a proof theory in labeled sequents that admits cut. We finally study Moorean phenomena and define a dynamic resolution operator for (...) priority merge for which we also provide a complete set of reduction axioms. (shrink)

In this paper, we investigate the social herding phenomenon known as informational cascades, in which sequential inter-agent communication might lead to epistemic failures at group level, despite availability of information that should be sufficient to track the truth. We model an example of a cascade, and check the correctness of the individual reasoning of each agent involved, using two alternative logical settings: an existing probabilistic dynamic epistemic logic, and our own novel logic for counting evidence. Based on this analysis, we (...) conclude that cascades are not only likely to occur but are sometimes unavoidable by "rational" means: in some situations, the group’s inability to track the truth is the direct consequence of each agent’s rational attempt at individual truth-tracking. Moreover, our analysis shows that this is even so when rationality includes unbounded higher-order reasoning powers, as well as when it includes simpler, non-Bayesian forms of heuristic reasoning. (shrink)