This document describes the technique and technology currently used to apply cryosurgery, a technic based on low temperatures for medical purposes that allows the controlled destruction of pathological cells and tissues. Cryosurgery is an effective and innocuous process that is painless, safe and economical, applied to multiple specialities in which it provides alternatives to its traditional methods. A search was carried out for articles and bibliographic reviews referring to Cryosurgery and from whose information this technical note was obtained. Research on (...) the application of Cryosurgery presents solid evidence of its benefits. Therefore, it has been used in several countries and health campaigns, showing excellent results, so it is advisable to implement it in health systems. (shrink)

In this paper, we argue that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques (MRTs). First, we provide a brief explanation of mitochondrial diseases and MRTs. We then present the reasons why MRTs are not, by nature, therapeutic. The upshot of the view that MRTs are non-therapeutic techniques is that their therapeutic potential cannot be invoked for restricting their use only to those cases where a (...) mitochondrial DNA disease could be ‘cured’. We then argue that a positive case for MRTs is justified by an appeal to reproductive freedom, and that the criteria to access these techniques should hence be extended to include lesbian couples who wish to share genetic parenthood. Finally, we consider a potential objection to our argument: that the desire to have genetically related kin is not a morally sufficient reason to allow lesbian couples to access MRTs. (shrink)

Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation and (...) in the scope of their potential applications. In this paper we develop an ethical framework, rooted in recent scientific evidence, to support a robust experimental pipeline that could enable the first-in-human use of IVG. We then apply this framework to the following objectives: (1) a clarification of the genetic parenting options afforded by IVG, along with their ethical underpinnings; (2) a defence of the use of IVG to remedy infertility, broadening their scope to same-sex couples; (3) an assessment of the most far-reaching implications of IVG for multiplex parenting. These include, first, the liberation of parenting roles from the constraints of biological generations in vivo, allowing multiple individuals to engage in genetic parenting together, thus blurring the distinction between biological and social generations. Second, we discuss the conflation of IVG with sequencing technology and its implications for the possibility that prospective parents may choose among a hitherto unprecedented number of potential children. In view of these perspectives, we argue that, contrary to the exhausted paradigm according to which society lags behind science, IVG may represent instead a salient and most visible instance where biotechnological ingenuity could be used in pursuit of social experimentation. (shrink)

This study delved into the Senior High School Technical-Vocational-Livelihood (TVL) track in Bohol Province for the 2022-2023 school year, aiming to evaluate policy implementation, recognize barriers, and propose interventions. Employing a mixed-method approach, integrating quantitative-descriptive surveys and qualitative-descriptive research methods as recommended by Creswell and Plano Clark (2017), the findings unveiled a predominantly positive perception of policy implementation across various dimensions of the TVL track. These encompass curriculum development, teacher training, resource allocation, industry partnerships, assessment and evaluation, student support services, (...) monitoring and quality assurance, policy adaptation and improvement, stakeholder engagement, legal framework and compliance, data collection and analysis, and inclusivity and equity. Despite variations among teachers and administrators, a general commitment to policy implementation emerged. The study identified barriers in curriculum and instruction, readiness and preparedness, resource limitations, and teaching and learning, emphasizing evidence-based strategies and interdisciplinary approaches to surmount challenges. It underscores the crucial role of research and policy development in elevating the quality and efficacy of TVL education. (shrink)

El problema que se pretende resolver en este texto es el aporte del diálogo filosófico como unaaventura y experiencia que cura. El texto se justifica toda vez que ante una experiencia filosófica enla que las preguntas fundamentales parecen ser la fuente del quehacer filosófico, aparece el diálogocomo una excelente oportunidad de transformar la existencia y curar los males que aquejan alhombre postmoderno. El objetivo del texto se enmarca en la experiencia vital del filósofo quese ha dedicado toda su vida a (...) dar respuesta a inquietudes existenciales pero que en los actualesmomentos le apuesta al diálogo como la mejor manera de curar los males que nos aquejan. Laexperiencia curativa desde el filosofar transforma al ser humano y lo prepara para enfrentarlas grandes problemáticas de su quehacer cotidiano. La metodología utilizada fue de enfoquedescriptivo en la que las fuentes permitieron acercarse a la argumentación dialógica del filosofar.La experiencia íntima de la filosofía se da gracias al diálogo filosófico que, más que método, es unaexperiencia que posibilita la relación conmigo mismo, con los otros y con las cosas a través de lapalabra, la razón y la sensación que surge en el devenir mismo del diálogo; esto es lo que lleva aentender el diálogo como una experiencia que cura y transforma. Por medio del diálogo filosófico,se logra un autoconocimiento que tiene el poder de curar, sanar, reparar y transformar a la personahumana, al “hombre de carne y hueso”. (shrink)

Cultural diversity is an inescapable reality and a concern in many businesses where it can often raise ethical questions and dilemmas. This paper aims to offer suggestions to certain problems facing managers in dealing with cultural diversity through the inspiration of Thomas Aquinas. Although he may be perceived as a voice from the distant past, we can still find in his writings helpful and original ideas and criteria. He welcomes cultural differences as a part of the perfection of the universe. (...) His systemic approach leads one to place the problem in its proper context, and to reflect on it from the perspective of virtue ethics, with a central role for practical wisdom and giving primacy to neighborly love and natural moral law. Rather than a set of rigid standards with no consideration of diversity Aquinas focuses on the common human ground, which allows for the indispensable dialogue between different positions. When dealing with practical questions, the problem is one of finding the right balance between general principle and cultural specifics, tolerance, and dialogue, always guided by practical wisdom. In this way, Aquinas’ approach is neither rigid ethical universalism with no consideration for diversity nor moral relativism with no place for any transcultural and absolute morals. (shrink)

El objetivo del presente artículo es fortalecer el aprendizaje y la calidad educativa en el trabajo colaborativo, evaluando estrategias didácticas y aplicando la estrategia de diseño de textos académicos en la licenciatura de Mercadotecnia, respondía a la cuestión ¿De qué manera la debilidad en el aprendizaje y baja calidad educativa en el trabajo colaborativo repercuten en las deficiencias de la aplicación de la estrategia didáctica del diseño de textos académicos? La investigación es de tipo mixto, la metodología de la Investigación–Acción. (...) El estudio dio resultados en el trabajo colaborativo porque ayudo a los alumnos a adquirir conocimientos. (shrink)

Esse texto procura explicitar a tese da compreensão atual que Simmel pressupõe como lócus de apreensão e interpretação dos processos humanos dotados de sentido. Para explicitá-la, confronta as posições de Dilthey e Simmel sobre o papel da vivência na fundamentação do conhecimento histórico. Ao contrário de Dilthey, no entanto, Simmel não pressupõe uma vivência que possa ser apreendida em outrem ou circunscrita a partir de um objeto, porque põe o fundamento da compreensão na atualidade daquele que compreende. Assim, opera com (...) possibilidades objetivas da construção de conexões de sentido por meio da projeção de processos psíquicos. Conquanto dificilmente seja lembrado no debate sobre a compreensão ou sobre a filosofia da história, Simmel possui uma posição própria e consistente acerca da fundamentação do conhecimento histórico, que pode ou abrir novos ângulos de pesquisa ou ser fecunda para se reexaminar perspectivas já consolidadas. (shrink)

The purpose of the article is to show that the foundations of a dualistic theology of Christian roots are found in the point of connection between platonic metaphysics, gnostic myths and exegesis. It highlights the way in which platonic metaphysics was developed in a completely different way than what is known as “Metaphysics of Exodus”. It considers that myth ─as an expressive vehicle of religious experience and having a polyvalent logic─ was a decisive element for the transmission of gnostic tradition. (...) Thus, the article concentrates on the gnostic understanding of “The Prologue of John”, which focuses on the Christological function of Jesus, bearing in mind the difficulties involved in the indifference with which this tradition dealt with Incarnation. The tools for the exegesis are taken from Hellenic tradition as a form to clarify the gnostic intuition concerning the stages of the propagation of the divine, both before and after the Fall. (shrink)

This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer and pronuclear transfer. Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, (...) it investigates whether there is a moral difference between MST and PNT from a human embryo destruction point of view. I conclude, contra recent arguments, that regarding the first two points there is no moral differences between PNT and MST; and that regarding the third one MST is morally preferable to PNT, but only if we hold a gradualist account of the moral value of human embryos where zygotes have slight moral value. (shrink)

Several objections against the morality of researching or employing mitochondrial replacement techniques have been advanced recently. In this paper, I examine three of these objections and show that they are found wanting. First I examine whether mitochondrial replacement techniques, research and clinical practice, should not be carried out because of possible harms to egg donors. Next I assess whether mitochondrial replacement techniques should be banned because they could affect the study of genealogical ancestry. Finally, I examine the claim that mitochondrial (...) replacement techniques are not transferring mitochondrial DNA but nuclear DNA, and that this should be prohibited on ethical grounds. (shrink)

El artículo estudia la emergencia de testimonios de torturados durante la dictadura militar y posteriormente de testimonios de víctimas de abusos sexuales y de conciencia por parte de sacerdotes chilenos, postulando que estamos frente un nuevo tipo de testimonio que emerge de situaciones de violencia. La pesquisa realiza un análisis semiótico de estos relatos estudiando axiomas que caracterizan este tipo de texto sosteniendo que estos textos poseen una relevancia epistémica y teológica esencial para la superación de la crisis eclesial.

En el presente artículo analizamos en sus aspectos fundamentales la evolución teórica que ha experimentado la interpretación de la obra de Marx desde las primeras corrientes que se derivan de ella hasta las más actuales. Nos ocupamos primero del marxismo tradicional, de su concepción determinista del materialismo histórico y su interpretación historicista de la teoría del valor. Abordamos después las corrientes del marxismo occidental que se oponen a las concepciones reduccionistas y economicistas de la interpretación marxista dominante, para centrarnos finalmente (...) en las interpretaciones más recientes de la teoría social de Marx como crítica del carácter fetichista de las formas de conciencia burguesas y las categorías de la economía política. (shrink)

In this article we follow the reception made by Augustine of Hippo of the Manichean myth; in this we see his visceral reaction against the doctrine of Mani, since –in addition to the apologetic elements properly– there is a clear attempt to take psychological distance from a religious experience that marked it in depth, in every way. In this controversial context we can also discern central aspects of a text that had liturgical value and which, as such, was of capital (...) importance to the Manichaean communities. This Augustinian reading has as horizon the near collapse of the Roman Empire of the West and the ever-increasing confrontation of Constantinople with Persian Empire, the mobility of its borders and the partly political and partly religious persecutions that Manichaeism underwent. (shrink)

The capability approach is gaining momentum as a theory of corporate responsibility and business ethics at a time when the UN Guiding Principles have become a most important framework. A novel approach is now emerging that seeks to understand and specify human rights obligations of businesses within the framework provided by the capability approach. This article partially examines the triad corporate responsibility–human rights–capability approach by exploring the relationship between human rights and capabilities. Thus, it offers conceptual and practical implications for (...) a human rights perspective on corporate responsibility. The bulk of our thesis focuses on studying Nussbaum’s and Sen’s claim that human rights are entitlements to capabilities by means of a discussion of the notion of human dignity. In particular, we show the capability approach’s ability to dissipate theoretical and practical challenges posed by the notion of dignity. This article does not offer a detailed explanation of the implications of our investigation for human rights responsibilities of business. However, an outline of its potential contribution toward unfolding those obligations, conceptually and practically, is provided. (shrink)

In this work I present a detailed critique of the dignity-related arguments that have been advanced against the creation of human–nonhuman chimeras that could possess human-like mental capacities. My main claim is that the arguments so far advanced are incapable of grounding a principled objection against the creation of such creatures. I conclude that these arguments have one, or more, of the following problems: they confuse the ethical assessment of the creation of chimeras with the ethical assessment of how such (...) creatures would be treated in specific contexts, they misrepresent how a being could be treated solely as means towards others’ ends, they fall short of demonstrating how humanity’s dignity would be violated by the creation of such entities, and they fail to properly characterise the moral responsibilities that moral agents have towards other moral agents and sentient beings. (shrink)

El encuentro de san Agustín con el aristotelismo tuvo dos vías: por un lado, las traducciones latinas de los comentaristas, que buscaban la integración de Platón y de Aristóteles, aunque señalando la primacía del primero; así el aristotelismo alcanzó un nuevo auge, pero bajo la dirección conceptual del neoplatonismo. Por otro lado, la lectura de las Categorías, en alguna de las traducciones latinas que circulaban en su época. En este doble marco de recepción, postulamos la presencia del principio aristotélico esse (...) in subiecto, en la argumentación sobre la inmortalidad del alma, y discernimos las consecuencias de este recurso. Si bien la teoría de la reminiscencia explicaba la procedencia del conocimiento como el recuerdo más verdadero, esta constituía una dificultad insuperable para una mentalidad creacionista; consideramos que el elemento aristotélico actúa sobre esta estructura platónica: la experiencia de las cosas no es recuerdo, sino evocación. Mediante el recurso del principio aristotélico, san Agustín transmuta la inmaterialidad del alma platónico-aristotélica en espiritualidad. (shrink)

Las democracias modernas no son perfectas. Por un lado, se ven afectados por problemas como la corrupción, el nepotismo y el populismo. Por otro lado, están moldeados por tecnologías, desde la impresión hasta la web. En los últimos años, académicos y tecnólogos han comenzado a explorar alternativas para aumentar, modificar, o mejorar la democracia. Estas incluyen propuestas teóricas y prácticas basadas en el uso de herramientas digitales, desde algoritmos que buscan maximizar la representatividad de foros deliberativos, a sistemas de datos (...) abiertos, recomendación de votos, y presupuestos participativos. Estas y otras propuestas tienen como objetivo mejorar la participación pública; reducir la vulnerabilidad de los sistemas democráticos representativos; aumentar la responsabilidad de los políticos; o simplemente ofrecer a los ciudadanos un mayor control y escrutinio de las acciones y decisiones políticas. (shrink)

The objective of this article was to address the Augustinian call to philosophical life. In discussion with academic skepticism, Saint Augustine exhorts his friend Romanian to search for wisdom and, for this, to also dismiss distrust and excessive confidence in reason, since he argues both against the skeptical position, or despair of finding the truth, and dogmatism or the assurance of having definitely found the truth. In fact, Saint Augustine points out the difficulty of taking knowledge for granted and, therefore, (...) does not rule out skepticism, but rather incorporates it as the initial phase of knowing and as an antidote to the naivety of giving absolute scope to the human faculty of human knowing. In the perspective of this balance, Saint Augustine exhorts Romanian to finish deciding to lead a philosophical life. To travel this path, in continuity with his Neoplatonic readings, he considers beauty as a guide: spiritual beauty is accessed by passing through the cosmic; the contemplating soul, insofar as it corresponds to what is contemplated, can thus reach the ascending path of its own transformation. The method of accessing the texts is philological, that is, it seeks at the same time to decipher the letter of the philosophical plot and to establish a contextual understanding of it. A method of this nature is inseparable from the conceptual framework; indeed, the formation of a philosophical knowledge, which tries to find the limits of the understanding of revelation, puts the person in tension of perfection, that is, it guides them towards their own transcendence. (shrink)

O trabalho analisa as relações entre discurso_ _e ser estabelecidas de forma dialética por Platão em seu diálogo tardio _Sofista_. Os sofistas defendiam a impossibilidade de provar a falsidade ou veracidade dos discursos. Tais pensadores baseavam-se no interdito ontológico de Parmênides de Eleia, que preconizava, em linhas gerais, a existência de uma estrita correspondência entre tudo que pode ser dito e o ser, de forma que seria, assim, impossível, dizer algo que não é, ou seja, um não-ser. Contrariando tal perspectiva (...) e fazendo uso do método da _diaíresis _– em que os seres são caracterizados por suas diferenças mais fundamentais –, o _Sofista _se desenrola revisitando e revisando as teorias ontológicas de seu tempo, a fim de explorar uma nova forma de pensar a relação entre os seres. Platão assegura, com isso, a possibilidade de análise qualitativa do discurso predicativo e define, consequentemente, o erro como desarmonia entre o dizer e o ser. Para tamanha empreitada, o filósofo explica como se dá o entrelaçamento na relação de ser e não-ser, relação mediada pelas seguintes categorias fundamentais: ser, mesmo, outro, movimento e repouso. A partir disso, a dialética é finalmente constituída como a técnica correta de diferenciação entre os predicados possíveis de comunicação com cada sujeito. Graças aos resultados filosóficos dessa empreitada, iniciaram-se as reflexões que levaram Aristóteles a instrumentalizar as análises da linguagem. (shrink)

O presente estudo visa esclarecer os pontos de convergência entre Paulo Freire e Anísio Teixeira referentes aos temas da produção da democracia no Brasil de fins da década de 1950. Para tanto, são tomados como fonte os textos de Freire Educação e atualidade brasileira e Educação como prática da liberdade. O cotejo das idéias de Anísio e Freire permite observar importantes convergências entre ambos, quanto ao papel da educação na formação dos hábitos democráticos e da construção da sociedade democrática, por (...) meio de grandes esforços educativos. Tal proximidade é bastante perceptível até a segunda obra freireana, Educação como prática da liberdade, ficando menos evidente nas obras posteriores. À medida que Freire produz novos textos e participa de novas experiências políticas e educativas, no Chile, junto aos camponeses, suas reflexões priorizam temas como a ruptura entre opressores e oprimidos e a revolução como ação cultural. (shrink)

Este artigo desenvolve uma leitura do livro de Jacques Derrida, Mal de arquivo, com o objetivo de situar o que se poderia chamar de concepção derridiana de arquivo. Ao desdobrar o potencial de conflito que se arquiva na própria palavra "arquivo", Derrida oferece uma concepção de arquivo que, para além das discussões desenvolvidas no livro em questão, abre a possibilidade de uma nova forma de se pensar o âmbito da política. This article develops a reading of Jacques Derrida's book, Archive (...) Fever, with the aim of circumscribing what could be named the Derridian conception of archive. By unfolding the conflictive power which is archived within the proper word "archive", Derrida comes with a conception of archive that, beyond the discussions developed in the book, opens the possibility of a new way of thinking the political. (shrink)

Si, pour Heidegger, Nietzsche représente le dernier penseur de la métaphysique, ce n’est pas seulement en raison de son appartenance à la conceptualité de l’onto-théologie ni des limites intrinsèques à sa tâche d’un renversement du platonisme. La lecture des traités et des cahiers posthumes concernant la pensée de l’ Ereignis précise la critique heideggérienne et la complète par l’opposition totale à la tentative d’un élevage ( Züchtung ) de l’être humain supérieur. En effet, Heidegger voit dans la notion d’élevage la (...) fixation voire la radicalisation, à l’époque de la fabrication ( Machenschaft ), de la définition métaphysique de l’être humain comme animal rationale. Contre la Züchtung nietzschéenne, il pense la possibilité d’une préparation ( Vorbereitung ) du Da-sein, comme la plus haute transformation de l’essence humaine. Ce sont les rapports de ces deux notions, l’élevage tel qu’il apparaît dans la critique heideggerienne de Nietzsche, et le concept qu’il lui oppose, la préparation, que nous analysons dans cet article, en exposant non seulement la manière dont l’un répond à l’autre, mais également les limites de ce couple de concepts. Par là, nous cherchons d’une part à mieux comprendre la place de Nietzsche dans le projet de l’histoire de l’Être, et, d’autre part, à déterminer la portée de son dépassement. (shrink)

Propõe-se neste ensaio uma análise filosófica dos dilemas morais e políticos a que fomos submetidos pela situação de pandemia da Covid-19. As dificuldades de muitas sociedades ocidentais no enfrentamento à pandemia têm posto em questão o paradigma liberal da preservação da vida, da privacidade e da liberdade a partir da adoção de políticas de austeridade estatal que se tornaram a orientação principal no combate ao coronavírus, e que não raro esbarram nos chamados _direitos individuais_ a que os orientais não parecem (...) familiarizados. Nossa reflexão pretende oferecer, pelo recurso à filosofia da Vontade de Schopenhauer, um diálogo entre as posturas oriental e ocidental em vista daquilo que nos é fundamental enquanto seres humanos: uma compreensão da condição de fragilidade da vida e dos limites inerentes à liberdade individual, orientados por uma noção de justiça inevitavelmente determinada pelas dores e sofrimentos imanentes ao mundo. (shrink)

El texto ofrece una semblanza del trabajo académico, filosófico del autor, de su vida.

En Ideas I, la fenomenología se presenta como “idealismo trascendental”. Esta investigación muestra que cinco años antes, en 1908, Husserl accedió a la formulación del “idealismo trascendental”, pero desde una vía diferente a la de Ideas I. En 1913 y hasta 1921, el fundador de la fenomenología retoma y desarrolla la fundamentación inicial del “idealismo trascendental”. Presentamos los rasgos fundamentales de esta “demostración” del “idealismo trascendental” y ponderamos hasta qué punto se abre la posibilidad de un “trascendentalismo metodológico”, camino hacia (...) una filosofía trascendental no-idealista. (shrink)

É a metafísica uma ciência a priori ou a posteriori’? Suárez e a fundamentação da metafísica Resumo: Contra a interpretação de François Courtine, Rolf Darge afirma que para Francisco Suárez a metafísica é uma ciência que trata do ente entendido não como aquilo que pode ser objeto para a mente humana, mas como aquilo que é apto a existir de fato. A metafísica seria uma ciência real, entre outras razões, porque ela é uma ciência a posteriori. Este artigo pretende verificar (...) melhor a afirmação de que a metafísica de Suárez é uma ciência a posteriori. Pois, se de fato for assim, a interpretação realista que Rolf Darge oferece da metafísica de Suárez adquire maior plausibilidade. Palavras-chave: objeto da metafísica; empirismo; realismo. Is metaphysics an a priori or an a posteriori Science? Suárez and the foundation of metaphysics. Abstract: Against the interpretation of François Courtine, Rolf Darge affirms that for Francisco Suárez metaphysics is a science that deals not with being as that which can be an object for the human mind, but with being as that which is apt to actually exist. Metaphysics would be a real science, among other reasons, because it is a posteriori science. This article aims to verify the claim that Suárez's metaphysics is a posteriori science. If this is so, the realistic interpretation that Rolf Darge offers of Suárez's metaphysics acquires greater plausibility. Key-words: object of metaphysics; empiricism; realism. La métaphysique est-elle une science a priori ou a posteriori? Suárez et le fondement de la métaphysique. Résumé: Contre l'interprétation de François Courtine, Rolf Darge affirme que pour Francisco Suárez la métaphysique est une science qui traite de l'étant compris non comme ce qui peut être un objet pour l'esprit humain, mais comme ce qui est susceptible d'exister réellement. La métaphysique serait une vraie science, entre autres raisons, car c'est une science a posteriori. Cet article vise à mieux vérifier l'affirmation selon laquelle la métaphysique de Suárez est une science a posteriori. S'il en est ainsi, l'interprétation réaliste que propose Rolf Darge de la métaphysique de Suárez acquiert une plus grande plausibilité. Mots-clés: objet de la métaphysique; empirisme; réalisme. Data de registro: 16/09/2021 Data de aceite: 20/10/2021. (shrink)

The aim of this paper is to critically examine David Shaw, Wybo Dondorp, and Guido de Wert’s arguments in favour of the procurement of human organs from human/nonhuman-primate chimeras, specifically from great-ape/human chimeras. My main claim is that their arguments fail and are in need of substantial revision. To prove this I first introduce the topic, and then reconstruct Shaw et al.’s position and arguments. Next, I show that Shaw et al.: (1) failed to properly apply the subsidiarity and proportionality (...) principles; (2) neglected species overlapping cases in their ethical assessment; (3) ignored the ethics literature on borderline persons; and (4) misunderstood McMahan’s two-tiered moral theory. These mistakes render an important part of their conclusions either false or problematic to the point that they would no longer endorse them. Finally I will briefly mention a possible multipolar solution to the human organ shortage problem that would reduce the need for chimeras’ organs. (shrink)

In this paper I explore some of the moral issues that could emerge from the creation of human–nonhuman chimeras capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that (...) could emerge from the fact that a HNH-chimera could become pregnant with a human conceptus. I focus on two sets of problems: problems that would arise by virtue of the fact that a human is gestated by a nonhuman creature, and problems that would emerge from the fact that such pregnancies could affect the health of the HNH-chimera. (shrink)

The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom (...) as the most likely location for the first MRT birth, so it was a shock when, on September 27, 2016, an announcement went out that the first baby to result from use of the intervention had already been born. In New York City, United States-based scientist John Zhang used maternal spindle transfer to generate five embryos for a woman carrying oocytes with deleterious mutations of the mitochondrial DNA. Zhang then shipped the only euploid embryo to Mexico, where it was transferred to the mother's uterus. Zhang's team's travel across international borders to carry out experimental procedures represents a form of scientific tourism that has not been properly ethically explored; it can, however, have seriously detrimental effects for developing countries. (shrink)

In this paper I argue that some human reproductive genome editing interventions can be therapeutic in nature, and thus that it is false that all such interventions just create healthy individuals. I do this by showing that the conditions established by a therapy definition are met by certain reproductive genome editing interventions. I then defend this position against two objections: (a) reproductive genome editing interventions do not attain one of the two conditions for something to be a therapy, and (b) (...) some reproductive genome editing interventions are therapeutic but in a nonstandard way. In the Conclusion I call for a more nuanced discussion of the nature of reproductive genome editing interventions. (shrink)

Francisco Romero es una de las personalidades más significativas de América Latina. Sus escritos, su labor pedagógica, la difusión de su pensamiento y el intercambio epistolar con figuras de renombre internacional dan muestra de ello. En el trabajo nos detenemos en este último aspecto para comprobar su manifiesta intención de construir una red intelectual de filósofos en América Latina. También están presentes las inquietudes editoriales tanto de Romero, como de sus pares mexicanos. Asimismo hacemos hincapié en el tópico del exilio (...) y la Guerra Civil Española a través de las cartas que el autor argentino recibió de algunos refugiados en México. El análisis de esta fuente histórica nos permite ver el estado del campo intelectual de la región en los años estudiados, al mismo tiempo que indica un panorama valioso del contexto histórico argentino y de América Latina. Francisco Romero is one of the most significant intellectuals in Latin America. His writings, his teaching, the dissemination of his thought, and the exchange of letters with internationally renowned figures are evidence of his legacy. In this paper we focus on this last aspect to prove the manifest intent of building an intellectual network of philosophers in Latin America. The editorial concerns of both Romero as well as his Mexican counterparts are present. We also focus on the topic of exile and the Spanish Civil War, through the letters that the Argentine author received from refugees in Mexico. The analysis of this historical source shows the state of the intellectual field of the region in the period studied, at the same time that it provides a valuable overview of the historical context in Argentina and Latin America. (shrink)

Análisis de la noción de retórica en Blumenberg.

O objetivo deste artigo é analisar a crítica de Waldron a Rawls, feita no livro “Law and Disagreement”. Queremos saber se nessa crítica está implícita a ideia de que Rawls faz uma má idealização. Para fazer isso, teremos, em primeiro lugar, que esclarecer o que é uma “teoria ideal” e o que são boas ou más idealizações. Falaremos sobre essas distinções na primeira seção do artigo. Waldron ataca a alegada incapacidade da teoria de Rawls de tratar seriamente os desacordos sobre (...) princípios políticos. A exposição dessa crítica e a análise de seu desenrolar vai ocupar as parcelas mais significativas do artigo, e será feita nas seções seguintes. Ao fim da análise, defenderemos que, apesar de a crítica de Waldron ser forte, ela não implica que há más idealizações de Rawls. (shrink)

En este ensayo pretendo señalar la experiencia y la práctica de la investigación cualitativa en Iberoamérica. Al comparar el estado del arte de la investigación cualitativa en diferentes países, este manuscrito es un primer esfuerzo por difundir el debate al que nos enfrentamos en nuestras sociedades de habla hispana en el contexto de la globalización de la academia. ¿Cómo se ve la investigación cualitativa iberoamericana a través de la globalización? ¿Cuáles son nuestras principales preocupaciones acerca de los métodos y enfoques? (...) ¿Está la hermenéutica incluida en nuestra agenda? En particular, voy a tomar en cuenta el contexto iberoamericano para señalar un conjunto determinado de obstáculos y desafíos de hacer investigación cualitativa en estos países. (shrink)

One of the most controvertible subjects in Martin Heidegger´s thinking is that about Deity; this article is an attempt to clarify his argument about it. In order to reach this point this article explain silence in Heidegger´s studies about God, and his critical approach, both topics address a nih..

What's New will present discussions of new methodologies or improvements of previously developed techniques. In this article, A. C. Cuello and C. Milstein discuss the present status of monoclonal antibody technology..

Este trabajo presenta una visión general al lector sobre el tema de la educación en el pensamiento de Karl Marx, basada en cuatro obras clásicas: Tesis sobre Feuerbach, el Manifiesto del Partido Comunista de los Trabajadores y de las Instituciones Crítica Asociación del Programa de Gotha de los cuales se considera el centro de a la comprensión de la educación en el contexto actual. Tomamos nota de que en Marx, el enfoque crítico de la educación en la sociedad capitalista contribuye (...) a las banderas históricas y las luchas políticas que hasta ahora "sangrar" el posicionamiento de la realidad a nosotros mismos a una vista que no renuncia a entender "cómo la sociedad llegó a este punto", y muy menos que el reto de atreverse a vivir una praxis revolucionaria, socialista y emancipador que deseamos! (shrink)