The rapid growth of next-generation genetic sequencing has prompted debate about the responsibilities of researchers toward genetic incidental findings. Assuming there is a duty to disclose significant incidental findings, might there be an obligation for researchers to actively look for these findings? We present an ethical framework for analyzing whether there is a positive duty to look for genetic incidental findings. Using the ancillary care framework as a guide, we identify three main criteria that must be present to give rise (...) to an obligation to look: high benefit to participants, lack of alternative access for participants, and reasonable burden on researchers. Our analysis indicates that there is no obligation to look for incidental findings today, but during the ongoing translation of genomic analysis from research to clinical care, this obligation may arise. (shrink)

During public health crises including the COVID-19 pandemic, resource scarcity and contagion risks may require health systems to shift—to some degree—from a usual clinical ethic, focused on the well-being of individual patients, to a public health ethic, focused on population health. Many triage policies exist that fall under the legal protections afforded by “crisis standards of care,” but they have key differences. We critically appraise one of the most fundamental differences among policies, namely the use of criteria to categorically exclude (...) certain patients from eligibility for otherwise standard medical services. We examine these categorical exclusion criteria from ethical, legal, disability, and implementation perspectives. Focusing our analysis on the most common type of exclusion criteria, which are disease-specific, we conclude that optimal policies for critical care resource allocation and the use of cardiopulmonary resuscitation (CPR) should not use categorical exclusions. We argue that the avoidance of categorical exclusions is often practically feasible, consistent with public health norms, and mitigates discrimination against persons with disabilities. (shrink)

The development of genomics has dramatically expanded the scope of genetic research, and collections of genetic biosamples have proliferated in countries with active genomics research programs. In this essay, we consider a particular kind of collection, national biobanks. National biobanks are often presented by advocates as an economic ‘‘resource’’ that will be used by both basic researchers and academic biologists, as well as by pharmaceutical diagnostic and clinical genomics companies. Although national biobanks have been the subject of intense interest in (...) recent social science literature, most prior work on this topic focuses either on bioethical issues related to biobanks, such as the question of informed consent, or on the possibilities for scientific citizenship that they make possible. We emphasize, by contrast, the economic aspect of biobanks, focusing specifically on the way in which national biobanks create biovalue. Our emphasis on the economic aspect of biobanks allows us to recognize the importance of what we call clinical labor—that is, the regularized, embodied work that members of the national population are expected to perform in their role as biobank participants—in the creation of biovalue through biobanks. Moreover, it allows us to understand how the technical way in which national biobanks link clinical labor to databases alters both medical and popular understandings of risk for common diseases and conditions. (shrink)

More and more areas of medicine involve subjects donating tissues to another — blood, organs, bone marrow, sperm, ova and embryos can all be transferred from one person to another. Within the technical frameworks of biomedicine, such fragments are generally treated as detachable things, severed from social identity once they are removed from a particular body. However an abundant anthropological and sociological literature has found that, for donors and patients, human tissues are not impersonal. They retain some of the values (...) of personhood and identity, and their incorporation often has complex effects on embodied identity. This article draws on feminist philosophy of the body to think through the implications of some of these practices. Specifically, it draws on the idea of intercorporeality, wherein the body image is always the effect of embodied social relations. While this approach is highly productive for considering the stakes involved in tissue transfer, it is argued that the concept of body image has been too preoccupied with the register of the visual at the expense of introceptive data and health/illness events. Empirical data around organ transplant and sperm donation are used to demonstrate that the transfer of biological fragments involves a profound kind of intercorporeality, producing identifications and disidentifications between donors and recipients that play out simultaneously at the immunological, psychic and social levels. (shrink)

In recent decades, some feminists have turned to the writings of Hannah Arendt in order to propose a truly emancipatory ethic of care or to find the principles that could lead to the political institutionalization of care. Nevertheless, the feminist interpretations of Hannah Arendt are particularly contrasted. According to Sophie Bourgault, this recourse to Hannah Arendt is deeply problematic, mainly because of her strong distinction between the private and public spheres. This article discusses the relevance of using Arendt’s concepts to (...) think about the institutionalization of care by Joan Tronto. Indeed, the most recent analyses developed on the politics of care are shaped by Arendt’s concepts such as power, amor mundi or by her conception of politics as a relationship. (shrink)

Jealousy has been disparaged as psychologically debilitating and morally flawed since well before Shakespeare wrote Othello and is indeed represented—particularly well—as far back as in Homer's portrayal of gods and goddesses in The Iliad. According to some of these traditional views, often shared by philosophers, psychologists and the general public, jealousy is the sign, if not of an irredeemably corrupt mind, then at least of an excessively possessive and insecure character. But does jealousy always indicate some sort of flaw or (...) failure? Is jealousy rerehensible in all contexts? In the present paper, I intend to suggest some modifications to the view that it is, by giving jealousy a more sympathetic and charitable hearing than it normally receives, and suggesting that jealousy might, in some cases, be justifiable. (shrink)

In the matter of the body, even comparative language—the very use of English today—is soaked through and through with the Cartesian version of the intuition of dualism: the idea that we are fundamentally a mind and a body that must be either related ingeniously, or else reduced to one another. Instead, by deliberately looking at genres that pertain to other aspects of being human, I seek to go deeper into texts that simply start elsewhere than with intuitions of dualism, even (...) while being engrossed in the category of the experiential ‘body’. (shrink)

Résumé L’usage du nombre par les élites constitue un mode de gestion systémique qui exploite le facteur de désintégration de chaque composante singulière. Son contre-modèle mathématique renvoie à la véritable concrétude géométrique développée par Alexandre Grothendieck. La victoire de l’homme moyen qui accompagne celle du techno-populisme, entraîne un manque de différenciation, une disparition des marges au profit de l’index des comportements sociaux visant à un équilibre, à une communication, à une sorte de pseudo-chuchotement où tout le monde serait d’accord par (...) simple utilisation de la moyenne statistique pour constituer l’idéal-type de l’homme contemporain qui résulte du fantasme de l’auto-organisation. (shrink)

This chapter explores the epistemic roles played by connectionist models of cognition, and offers a formal analysis of how connectionist models explain. It looks at how other types of computational models explain. Classical artificial intelligence (AI) programs explain using abductive reasoning, or inference to the best explanation; they begin with the phenomena to be explained, and devise rules that can produce the right outcome. The chapter also looks at several examples of connectionist models of cognition, observing what sorts of constraints (...) are used in their design, and how their results are evaluated. It argues that the point of implementing networks roughly analogous to neural structures is to discover and explores the generic mechanisms at work in the brain, not to deduce the precise activities of specific structures. The chapter explores a formal analysis of the explanations offered, which interprets connectionist models and the cognitive theories they represent as sharing membership in a type of mechanism. (shrink)

Activists’ investigations of animal cruelty expose the public to suffering that they may otherwise be unaware of, via an increasingly broad-ranging media. This may result in ethical dilemmas and a wide range of emotions and reactions. Our hypothesis was that media broadcasts of cruelty to cattle in Indonesian abattoirs would result in an emotional response by the public that would drive their actions towards live animal export. A survey of the public in Australia was undertaken to investigate their reactions and (...) responses to. The most common immediate reaction was feeling pity for the cattle. Women were more likely than men to feel sad or angry. Most people discussed the media coverage with others afterwards but fewer than 10 % contacted politicians or wrote to newspapers. We conclude that the public were emotionally affected by the media coverage of cruelty to cattle but that this did not translate into significant behavioral change. We recommend that future broadcasts of animal cruelty should advise the public of contact details for counseling and that mental health support contacts, and information should be included on the websites of animal advocacy groups to acknowledge the disturbing effect animal cruelty exposes can have on the public. (shrink)

The French medical context is characterized by institutionalization of the ethical reflection in health care facilities and an important disparity between spaces of ethical reflection. In theory, the healthcare professional may mobilise an arsenal of resources to help him in his ethical reflection. But what happens in practice? We conducted semi-structured interviews with 22 health-care professionals who did and did not have recourse to clinical ethical committees. We also implemented two focus groups with 18 professionals involved in various spaces of (...) ethical reflection in order to let them debate about a better way to organize ethical reflection in their institutional contexts. The qualitative analysis allows to us to underline the coexistence of different conceptions of ethics among health care professionals. We also observed that the participants in our study shared the experience of ethically problematic situations as roadblocks in the process of communication and decision-making. We therefore report the factors which favour or inhibit the ethical course leading to the resolution or at the very least soothing of the situation at hand. Finally, we discuss methodological issues and underline the fact that while the patient is at the heart of the professional’s ethical preoccupations, this does not imply that they are actors in decisions that concern them. (shrink)

The pattern of impairments exhibited by some individuals on the autism spectrum appears to challenge the relevance-theoretic account of metaphor ( Carston, 1996, 2002 ; Sperber and Wilson, 2002 ; Sperber and Wilson, 2008 ). A subset of people on the autism spectrum have near-normal syntactic, phonological, and semantic abilities while having severe difficulties with the interpretation of metaphor, irony, conversational implicature, and other pragmatic phenomena. However, Relevance Theory treats metaphor as importantly unlike phenomena such as conversational implicature or irony (...) and like instances of ordinary literal speech. In this paper, I show how Relevance Theory can account for the prima facie incongruity between its treatment of metaphor and the case of individuals with autism. (shrink)

Résumé Des Principes de l’Architecture, de la Sculpture, de la Peinture et des autres Arts qui en dépendent - avec un Dictionnaire des termes propres à chacun de ces Arts ont été publiés en 1676. Contemporain du système des Académies établi par Colbert, le livre est destiné à décrire et fixer par des mots précis la pratique des arts figuratifs dans la France de Louis XIV et forme ainsi la première encyclopédie méthodique et illustrée qui en ait traité. L’article s’intéresse (...) à la théorie poïétique sous-jacente à l’édifice que Félibien consacre aux « plus beaux des Arts ». Loin du dogmatisme que l’on prête trop souvent au propos académicien, cette théorie s’avère avant tout attentive aux spécificités irréductibles de chacune des pratiques dont elle rend compte et ne parvient à la sûreté du discours, qu’une fois l’épreuve faite des limites rencontrée par la rationalité lorsque celle-ci se tourne vers les ouvrages d’art. (shrink)

Relevance Theory is a cognitively oriented theory of pragmatics, i.e., a theory of language use. It builds on the seminal work of H.P. Grice1 to develop a pragmatic theory which is at once philosophically sensitive and empirically plausible (in both psychological and evolutionary terms). This entry reviews the central commitments and chief contributions of Relevance Theory, including its Gricean commitment to the centrality of intention-reading and inference in communication; the cognitively grounded notion of relevance which provides the mechanism for explaining (...) pragmatic interpretation as an intention-driven, inferential process; and several key applications of the theory (lexical pragmatics, metaphor and irony, procedural meaning). Relevance Theory is an important contribution to our understanding of the pragmatics of communication. (shrink)

Hume's theory of mind is often interpreted in associationist terms, portraying the mind as psychological and social. It is also argued that in his most famous philosophical works Hume has an irreligious agenda. These views are problematic because they overlook the issue of social obedience to political authority. By contrast, I examine the connections between Hume's works and those of Bayle and Montaigne. I argue that the French context of Hume's social theory sheds a new light on the dual mind. (...) Indebted to a French Pyrrhonian heritage, Hume invokes custom as an explanatory concept in psychology and in the natural history of society. He also introduces religious analogies as he adopts a historical perspective in social and political theory. Along with custom, faith is crucial in his theory of government. The double nature of the mind thus corresponds to two distinct approaches: the customary mind engaging in profane, habitual activities; and the faithful mind participating in the sacred. Hume's analogy between society and secular religion is comparable to Durkheim's anthropology of rituals. Hume's affinity with Montaigne, Bayle, and Durkheim concerning to the duality of the mind, as customary and faithful, emphasises his role in the history of the French humanities. (shrink)

Focalisé sur un problème posé par Bernard Frenicle de Bessy vers 1639, sa solution et les réponses de ses correspondants, cet article s'attache à décrire plusieurs registres enchevêtrés de l'expérience du mathématicien: expérimentation sur les nombres empruntée en partie aux sciences de la nature, injonctions d'une pratique collective cimentée par les problèmes et leurs constructions explicites, entraînement personnel de l'attention et du savoir-faire s'articulent ainsi dans les efforts de Frenicle pour contester la suprématie de l'analyse algébrique et dans les modes (...) de conviction qui fondent son travail. Ce récit d'expérience permet en retour d'apprécier les problèmes que posèrent à Frenicle la transmission de ses résultats et, à ses historiens, la restitution de son activité. (shrink)

Cognitive scientists routinely distinguish between controlled and automatic mental processes. Through learning, practice, and exposure, controlled processes can become automatic; however, whether automatic processes can become deautomatized – recuperated under the purview of control – remains unclear. Here we show that a suggestion derails a deeply ingrained process involving involuntary audiovisual integration. We compared the performance of highly versus less hypnotically suggestible individuals in a classic McGurk paradigm – a perceptual illusion task demonstrating the influence of visual facial movements on (...) auditory speech percepts. Following a posthypnotic suggestion to prioritize auditory input, HSIs but not LSIs manifested fewer illusory auditory perceptions and correctly identified more auditory percepts. Our findings demonstrate that a suggestion deautomatized a ballistic audiovisual process in HSIs. In addition to guiding our knowledge regarding theories and mechanisms of automaticity, the present findings pave the road to a more scientific understanding of top-down effects and multisensory integration. (shrink)

Genetic resources are a key resource for much biomedical research. Pathogenic genetic resources are of value in the identification, surveillance, understanding, and development of vaccines, treatments, and other responses to major public threats such as pandemic influenza outbreaks. Significant attempts have been made to improve the international governance of infectious disease over the last decade, but the handling of pathogenic genetic resources remains contentious and problematic. The need to address the deficiencies in current arrangements (e.g., the World Health Organization's Pandemic (...) Influenza Preparedness Framework) is urgent because future outbreaks are likely to revert to the past situation in which developed states secured vaccine supplies for their own populations while leaving developing countries vulnerable to the pandemic. Thereby, the collaboration of developed countries with vital international systems such as the Global Influenza Surveillance and Response System is disincentivized. The current international approach to pathogenic genetic resources is based on the sovereign rights of states and access and benefit-sharing arrangements that stem from those rights. While this approach is consistent with international rules on other types of genetic resources, herein I argue that this is an inappropriate approach to pathogens on both political (serving public health goals) and ethical grounds (e.g., equity and justice). Instead I argue for a (modified) common heritage approach to pathogenic genetic resources, based on their intrinsic qualities (e.g., rapid mutation, easy transmissibility) and their value to global efforts to respond to disease outbreaks. I will further argue for de-linking access to these resources from benefit-sharing requirements; explaining that while there are strong justifications for both, their linkage (particularly for pathogenic genetic resources) is problematic and detrimental to the achievement of its intended goals (i.e., ensuring equitable benefit-sharing in return for access being granted). (shrink)

This essay offers a defence of the non-cognitivist approach to the interpretation of moral judgments as disguised imperatives corresponding to social rules. It addresses the body of criticism that faced R. M. Hare, and that currently faces moral anti-realists, on two levels, by providing a full semantic analysis of evaluative judgments and by arguing that anti-realism is compatible with moral aspiration despite the non-existence of obligations as the externalist imagines them. A moral judgment consists of separate descriptive and prescriptive components (...) and is to be understood as a declarative statement prefaced by an 'ideality operator'. Moral beliefs are genuinely representational, but their truth conditions can only be stated with reference to imaginary ideal worlds. Moral judgments are neither confirmed nor verified, but alternative moral positions are preferentially endorsed and adopted by individual agents on the basis of their perceived all-things-considered optimality. High aspiration moralities are normally very costly to agents in terms of their prudential and aesthetic interests, but they are theoretically as eligible as the adoption of other, less demanding sets of rules. (shrink)

In treatments of the relation of Chinese thought to pragmatism, pragmatism most commonly refers to the philosophy of John Dewey, and such treatments look to the Chinese past, whether recent or distant, not to contemporary Chinese philosophy. Nearly a century ago Dewey became the foremost exponent of pragmatism, both in the English-language world and also around the globe. In China, Dewey’s student Hu Shi was a seminal figure in the New Culture Movement. Dewey himself had a direct effect on Chinese (...) intellectuals during the just over two-year period that he spent lecturing and teaching in China between May 1919 and July 1921, his most immediate impact being in the arena of education.1 Beyond studies of... (shrink)

Moral properties are widely held to be response‐dependent properties of actions, situations, events and persons. There is controversy as to whether the putative response‐dependence of these properties nullifies any truth‐claims for moral judgements, or rather supports them. The present paper argues that moral judgements are more profitably compared with theoretical judgements in the natural sciences than with the judgements of immediate sense‐perception. The notion of moral truth is dependent on the notion of moral knowledge, which in turn is best understood (...) as a possible endpoint of theory change for the better. (shrink)