De generationewas the last of the three works published by William Harvey during his lifetime. Although this work on generation was most ambitious, being the product of prolonged and detailed researches, it has received relatively little attention from modern writers. It is generally felt that this work, like William Gilbert'sDe mundo, departs significantly from the more pronounced empirical approach to science which characterized Harvey's first publication,De motu cordis. De generationeshows that Harvey regarded reference to teleological and vitalistic principles as necessary (...) for the solution of crucial problems in biology. In this respect he differed from his contemporaries, the iatrochemical and iatromechanical physiologists, whose non-teleological approach seems, at least superficially, to be in sympathy with the modern biological tradition. The structure and content ofDe generationeare so evidently determined by Aristotle's biological writings, that the work is used to illustrate Harvey's failure to emancipate himself from the philosophical encumbrances of antiquity. (shrink)

This paper is intended to stimulate debate amongst stakeholders in the international research community on the topic of returning individual genetic research results to study participants. Pharmacogenetics and disease genetics studies are becoming increasingly prevalent, leading to a growing body of information on genetic associations for drug responsiveness and disease susceptibility with the potential to improve health care. Much of these data are presently characterized as exploratory (non‐validated or hypothesis‐generating). There is, however, a trend for research participants to be permitted (...) access to their personal data if they so choose. Researchers, sponsors, patient advocacy groups, ethics committees and regulatory authorities are consequently confronting the issue of whether, and how, study participants might receive their individual results. Noted international ethico‐legal guidelines and public policy positions in Europe and the United States are reviewed for background. The authors offer ‘Points‐to‐Consider’ regarding returning research results in the context of drug development trials based on their knowledge and experience. These considerations include: the clinical relevance of data, laboratory qualifications, informed consent procedures, confidentiality of medical information and the competency of persons providing results to participants. The discussion is framed as a benefit‐to‐risk assessment to balance the potential positive versus negative consequences to participants, while maintaining the integrity and feasibility of conducting genetic research studies. (shrink)

ABSTRACT This paper is intended to stimulate debate amongst stakeholders in the international research community on the topic of returning individual genetic research results to study participants. Pharmacogenetics and disease genetics studies are becoming increasingly prevalent, leading to a growing body of information on genetic associations for drug responsiveness and disease susceptibility with the potential to improve health care. Much of these data are presently characterized as exploratory (non‐validated or hypothesis‐generating). There is, however, a trend for research participants to be (...) permitted access to their personal data if they so choose. Researchers, sponsors, patient advocacy groups, ethics committees and regulatory authorities are consequently confronting the issue of whether, and how, study participants might receive their individual results. Noted international ethico‐legal guidelines and public policy positions in Europe and the United States are reviewed for background. The authors offer ‘Points‐to‐Consider’ regarding returning research results in the context of drug development trials based on their knowledge and experience. These considerations include: the clinical relevance of data, laboratory qualifications, informed consent procedures, confidentiality of medical information and the competency of persons providing results to participants. The discussion is framed as a benefit‐to‐risk assessment to balance the potential positive versus negative consequences to participants, while maintaining the integrity and feasibility of conducting genetic research studies. (shrink)

This study tests the hypothesis that the perception of philosophy as a male-oriented discipline contributes to the pronounced gender disparity within the field. To assess the hypothesis, we determined the extent to which individuals view philosophy as masculine, and whether individual differences in this correspond with greater identification with philosophy. We also tested whether identification with philosophy correlated to interest in it. We discovered, first, that the more women view philosophy as masculine, the less they identify with it, and second, (...) that the less women identify with philosophy, the less they want to major in it. Interestingly, this result does not hold for men—their viewing philosophy as masculine does not correspond to their identification with it, nor does it correlate with their likelihood of majoring in it. We also discovered that the typical student does not have a preconceived notion of philosophy as masculine; this suggests that they come to view philosophy as masculine the more they do it, which in turn supports the possibility that teaching the discipline differently may prevent students from conceiving of philosophy as masculine, thus allowing a path to reducing the gender disparity. (shrink)

From the time of the publication of Henry More's first work, the collection of poems, ΨγΧΩΔΙΑ Platonica , Platonism provided the dominant theme in his philosophy. At Cambridge, More, his colleague, Ralph Cudworth, and their disciples, were responsible for a considerable revival of English Platonism, which became an important factor in late seventeenth-century natural philosophy. This movement is noted for its active and influential opposition to the mechanical world view, characterized in the writings of Hobbes and Descartes.

The emergence of Big Data has added a new aspect to conceptualizing the use of digital technologies in the delivery of public services and for realizing digital governance. This article explores, via the ‘value-chain’ approach, the evolution of digital governance research, and aligns it with current developments associated with data analytics, often referred to as ‘Big Data’. In many ways, the current discourse around Big Data reiterates and repeats established commentaries within the eGovernment research community. This body of knowledge provides (...) an opportunity to reflect on the ‘promise’ of Big Data, both in relation to service delivery and policy formulation. This includes, issues associated with the quality and reliability of data, from mixing public and private sector data, issues associated with the ownership of raw and manipulated data, and ethical issues concerning surveillance and privacy. These insights and the issues raised help assess the value of Big Data in government and smart city environments. (shrink)

This paper seeks to demonstrate that propositions 23–27 of the Euclidian Optics originated in the context of geometrical astronomy. These entries, which deal with the geometry of spheres and rays, present material that overlaps considerably with propositions 1–3 of Aristarchus of Samos’ On the Sizes and Distances of the Sun and the Moon. While all these theorems deal with material that could conceivably be native to celestial illumination, the proofs do not work for binocular vision. It therefore seems probable that (...) the proofs were borrowed from Aristarchus or, more likely, some common astronomical predecessor. As an extension of this observation, this paper argues that the Optics displays a far less unified purpose than has typically been assumed. Instead, it reflects a conglomerate of concerns, goals and dependencies, insofar as it presents multiple proofs that emerge from a set of geometrical concerns not directly related to vision as a physical phenomenon. These entries complicate the idea that the Optics is about explaining light, sight or false appearances in any straightforward sense. Instead, the text is oriented toward a somewhat more diffuse goal: simply to articulate the geometry of vision and rays. Optics as a discipline should should therefore be understood not as a purely mathematical explanation of vision, but as a target-field of explanation constituted by features and boundaries derived from extra-visual geometric concerns. (shrink)

Religion is one lens in which people understand the world around them and interpret the world around them. However, it is unclear whether religion has an impact upon attitudes towards robots around the world. In this article, the authors investigate how an individual’s religiosity impacts upon perceptions of robots. The article investigates how an individual’s religiosity impacts attitudes towards robots, using data from a large-scale global survey of attitudes towards robots (N=1263). In order to investigate how religion impacts upon such (...) perceptions, cluster, factor and regression analyses were used for data analysis. The findings illustrate that there are discernible clusters of individuals exhibiting different levels of religiosity and that these clusters have different perceptions of robots, showing as hypothesized, that more religious individuals are more likely to be robophobic than robophilic. The relationship between religiosity and attitudes towards robots is negative: less religious people show more positive attitudes towards robots. While there is clear indication that there is a relationship between religiosity and attitudes towards robots, religiosity does not have a particularly strong impact upon perceptions of robots. The analysis of the data illustrates that there are factors more clearly associated with perceptions of robots, meaning that while religiosity may have some impact on perceptions of robots, that there are more important attitudes and other factors that should be taken into consideration to encourage users to use robots in various service environments. In addition, in this particular research, there seems to be no notable relationship between perceptions of robots and demographics of individuals, illustrating that the age, gender, wealth, and education of an individual may not play a strong role in shaping perceptions of robots in service industries. (shrink)

Empirical data from a large sample of Canadian youth aged 13 to 17 years suggest that, although the current privacy policy framework is having a positive effect on the extent to which young people are complying with the types of behavior promoted by adults as privacy protective, its primary focus on parental supervision is inadequate to fully protect children's online privacy. Respondents with high levels of either social interaction or identity play are more likely than those with lower levels to (...) divulge personal identifiers and display privacy-risky behavior, independent of their level of parental supervision. High levels of parental supervision, therefore, do not eliminate but merely reduce privacy-risky behaviors associated with social uses of the Internet. As such, parental supervision cannot adequately protect children who have integrated the Net most fully into their social lives, especially given the high premium that children place on the use of the Net to talk to friends and explore social roles. (shrink)

This article explores the emergence of standards and regulation associated with the provision of Closed Circuit Television (CCTV) surveillance systems in the United Kingdom. It argues that despite the intrusive and controlling nature of CCTV technology there is limited formal intervention in the form of legislation, governing its introduction and use. Instead government has sought to influence the regulation of the technology indirectly through its ability to shape and govern policy networks in the policy arena. In doing so, it is (...) argued here, that government remains the dominant actor in the policy process. (shrink)