Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

Latour is a world famous and widely published French sociologist who has written with great eloquence and perception about the relationship between people, science, and technology. He is also closely associated with the school of thought known as Actor Network Theory. In this book he sets out for the first time in one place his own ideas about Actor Network Theory and its relevance to management and organization theory.

The development of science studies has an important message for political theory. This message has not yet been fully articulated. It seems that the science studies field is often considered as the extension of politics to science. In reality, case studies show that it is a redefinition of politics that we are witnessing in the laboratories. To the political representatives should be added the scientific representatives. Thanks to a book by Steven Shapin and Simon Schaffer, it is possible to reconstruct (...) the origin of this divide between the two sets of representatives. A definition of modernism is offered. Then the article explains how to interpret the shift to "nonmodernism, " that is, a historical period when the two branches of politics get together again. (shrink)

Chapter 1 FROM ORDER TO DISORDER 5 mins. John enters and goes into his office. He says something very quickly about having made a bad mistake. He had sent the review of a paper. . . . The rest of the sentence is inaudible. 5 mins.

In this article, we present a few lessons we learnt in the establishment of the Sciences Po médialab. As an interdisciplinary laboratory associating social scientists, code developers and information designers, the médialab is not one of a kind. In the last years, several of such initiatives have been established around the world to harness the potential of digital technologies for the study of collective life. If we narrate this particular story, it is because, having lived it from the inside, we (...) can provide an intimate account of the surprises and displacements of digital research. Founding the médialab in 2009, we knew that we were leaving the reassuring traditions of social sciences to venture in the unexplored territory of digital inscriptions. What we couldn't foresee was how much such encounter would change our research. Buying into gospel of Big Data, we imagined that the main novelty of digital research came from handling larger amounts of data. We soon realized that the interest of digital inscriptions comes instead from their proliferating diversity. Such diversity encouraged us to reshape our professional alliances, research practices and theoretical perspectives. It also led us to overcome several of the oppositions that used to characterize social sciences and to move in the direction of a more continuous sociology. (shrink)

Eye movements during mental imagery are not epiphenomenal but assist the process of image generation. Commands to the eyes for each fixation are stored along with the visual representation and are used as spatial index in a motor‐based coordinate system for the proper arrangement of parts of an image. In two experiments, subjects viewed an irregular checkerboard or color pictures of fish and were subsequently asked to form mental images of these stimuli while keeping their eyes open. During the perceptual (...) phase, a group of subjects was requested to maintain fixation onto the screen's center, whereas another group was free to inspect the stimuli. During the imagery phase, all of these subjects were free to move their eyes. A third group of subjects (in Experiment 2) was free to explore the pattern but was requested to maintain central fixation during imagery. For subjects free to explore the pattern, the percentage of time spent fixating a specific location during perception was highly correlated with the time spent on the same (empty) locations during imagery. The order of scanning of these locations during imagery was correlated to the original order during perception. The strength of relatedness of these scanpaths and the vividness of each image predicted performance accuracy. Subjects who fixed their gaze centrally during perception did the same spontaneously during imagery. Subjects free to explore during perception, but maintaining central fixation during imagery, showed decreased ability to recall the pattern. We conclude that the eye scanpaths during visual imagery reenact those of perception of the same visual scene and that they play a functional role. (shrink)

The French and German political economies have been significantly reconfigured over the past two decades. Although the changes have often been more piecemeal than revolutionary, their cumulative effects are profound. The authors characterize the changes that have taken place as involving the institutionalization of new forms of dualism and argue that what gives contemporary developments a different character from the past is that dualism is now explicitly underwritten by state policy. They see this outcome as the culmination of a sequence (...) of developments, beginning in the field of industrial relations, moving into labor market dynamics, and finally finding institutional expression in welfare state reforms. Contrary to theoretical accounts that suggest that institutional complementarities support stability and institutional reproduction, the authors argue that the linkages across these realms have helped to translate employer strategies that originated in the realm of industrial relations into a stable, new, and less egalitarian model with state support. (shrink)

Bruno Latour is best known for his work in the cultural study of science. In this pamphlet he turns his attention to another worthy pursuit: the project of peace. As one might expect, Latour gives us a radically different picture of this project than Kant or the philosophes, asserting that the West has been in a constant state of war both with other cultures and its own—although unwittingly so. Read through the lens of his trademark take on "the modern," (...) his arguments are original, thoughtful, and, as usual, provocative. (shrink)

English summary: Snell's magnum opus The Discovery of the Mind was in 1946 important for the reorientation of the postwar generation wrote DIE ZEIT upon Bruno Snell's 90th birthday in 1986. His continuously expanded compilations, dealing with studies on the formation of the European spirit by the Greeks, have since been translated into many world languages. Sixty years after their, first publication they have not lost inspiration. For his student Walter Jens, The Discovery of the Mind is the work (...) of a Hellenist, who is also an excellent writer. German description: Snells Hauptwerk Die Entdeckung des Geistes war 1946 wichtig fur die Neuorientierung der Nachkriegsgeneration, befand DIE ZEIT zu Bruno Snells 90. Geburtstag 1986. Seine in diesem Buch zusammengestellten und immer wieder erweiterten Studien zur Entstehung des europaischen Geistes bei den Griechen sind seither in alle Weltsprachen ubersetzt worden. Sie haben auch sechzig Jahre nach ihrer Erstveroffentlichung nichts von ihrer Inspiration verloren. Fur seinen Schuler Walter Jens ist Die Entdeckung des Geistes das Buch eines Grazisten, der ein vorzuglicher Schriftsteller ist. Die hier vorliegende 9. Auflage ist gegenuber der 8. Auflage unverandert. (shrink)

One of the most debated questions in psychology and cognitive science is the nature and the functioning of the mental processes involved in deductive reasoning. However, all existing theories refer to a specific deductive domain, like syllogistic, propositional or relational reasoning.Our goal is to unify the main types of deductive reasoning into a single set of basic procedures. In particular, we bring together the microtheories developed from a mental models perspective in a single theory, for which we provide a formal (...) foundation. We validate the theory through a computational model (UNICORE) which allows fine‐grained predictions of subjects' performance in different reasoning domains.The performance of the model is tested against the performance of experimental subjects—as reported in the relevant literature—in the three areas of syllogistic, relational and propositional reasoning. The computational model proves to be a satisfactory artificial subject, reproducing both correct and erroneous performance of the human subjects. Moreover, we introduce a developmental trend in the program, in order to simulate the performance of subjects of different ages, ranging from children (3–6) to adolescents (8–12) to adults (>21). The simulation model performs similarly to the subjects of different ages.Our conclusion is that the validity of the mental model approach is confirmed for the deductive reasoning domain, and that it is possible to devise a unique mechanism able to deal with the specific subareas. The proposed computational model (UNICORE) represents such a unifying structure. (shrink)

En este trabajo, proponemos un marco metafísico naturalista para una variante del posibilismo basada en una concepción bilocalizada de la modalidad. Luego de revisar problemas característicos de posiciones alternativas, exploramos la aplicación de este marco al caso de la interpretación modal-hamiltoniana de la mecánica cuántica. Finalmente, revisamos problemas previos a la luz de esta nueva propuesta.

The goal of this study is to characterize observers’ abilities to detect gradual changes and to explore putative dissociations between conscious experience of change and behavioral adaptation to a changing stimulus. We developed a new experimental paradigm in which, on each trial, participants were shown a dot pattern on the screen. Next, the pattern disappeared and participants had to reproduce it. In some conditions, the target pattern was incrementally rotated over successive trials and participants were either informed or not of (...) this change. We analyzed both awareness of the changes and the dynamics of behavioral adaptation, in a way that makes it possible to assess both variability and accuracy as they change over time. Results indicate a dissociation between change awareness and behavioral adaptation to the changes, and support the notion that unconscious representations of visual stimuli are more precise and detailed than previously suggested. We discuss the implications of these results for theories of change detection. (shrink)

Este artigo parte do entendimento de que a cientificidade na pedagogia exigiu desta área do conhecimento suprimir a experiência como elemento vital da formação do homem, enquanto elevava a comprovação e regularidade do experimento ao patamar de destaque nos seus processos. A partir desta consideração, pretende-se tratar da transformação do conceito de experiência no campo educativo. Inicialmente, abordam-se as questões relacionadas à terminologia e significação do conceito “experiência” e sua possível transformação em “experimento”, e os desdobramentos dessa transição no campo (...) pedagógico. Na sequência, analisa-se a transformação do valor da experiência que passa a ser reconhecida enquanto experimento científico aplicado à pedagogia. Para tanto, apresenta-se, a partir da leitura da literatura educacional especializada, sobretudo os manuais dedicados à formação de professores, como é abordada a temática da Pedagogia Científica, ou seja, a construção dos discursos acerca da modernização da educação por meio de obras que apresentaram expressiva circulação no Brasil durante século XX. Dentre os resultados foi possível apreender o estabelecimento de uma pedagogia do experimento, ou, em outros termos, uma biopsicopedagogia como modelo estruturante do campo teórico da pedagogia com repercussão na formação de professores, e na predominância da problemática do ensino e da aprendizagem, ou seja, a intervenção metodológica em detrimento da formação integral do homem. Por fim, chega-se à conclusão de que se está, de um lado, diante dos impeditivos de realização da experiência e, de outro lado, diante de uma demanda, cada vez mais presente, de romper com o modelo pedagógico da modernidade, rumo aos novos desafios da educação de um homem que não se deixa mais ser, simplesmente, formado. Palavras-chave: Experiência. Experimento. Educação. Pedagogia. (shrink)

O presente trabalho trata da relevância da justiça para a crítica/justificativa do Direito, enquanto forma de estruturar as instituições sociais. Tendo Uma Teoria da Justiça como foco, a questão central neste ensaio é: como Rawls mobiliza os conceitos jurídicos? O objetivo geral é dialogar com os elementos centrais da obra de Rawls buscando compreender qual o papel do Direito no argumento em defesa da justiça como equidade. Para tanto, primeiro, retoma-se sucintamente os objetivos gerais pretendidos por Rawls com a teoria (...) elaborada. Em seguida, articula-se o uso de conceitos jurídicos com os objetivos pretendidos pelo autor em cada uma das três partes, para, então, enfatizar a serventia da justiça como equidade e da teoria política normativa aos juristas. Percorridos esses passos, defende-se a seguinte hipótese: o Direito é um elemento central na Teoria da Justiça de Rawls. Como desdobramento da hipótese, defende-se que para sustentar seu argumento central e desenvolver os principais elementos conceituais de sua obra, Rawls precisou recorrer aos conceitos jurídicos. (shrink)

The texts of the book are concerned with G. Bergmann's open and new problems and their active role on issues in contemporary metaphysics, like the ontology of ties, connexions and relations, problems of exemplification, substrates and tropes theories, particulars, persistence and the metaphysics of space, time and existence. Papers deal with these themes by themselves, or discuss them in an associated way: some of them aim to clarify the complicated conceptual Relations Bergmann have enlarged with major themes of philosophers like (...) Aristotle, Brentano, Meinong and Sellars. The purpose of the book is to provide some light on his central interests, but also in regard of the evolution of the actual scope of his thought. (shrink)

Im Gegensatz zu einer verbreiteten Sichtweise seiner politischen Philosophie sieht Aristoteles gerade in einer mangelhaften oder bruchigen Ordnung das Hauptproblem seiner Zeit. Diese Studie legt eine Deutung vor, die bei den aristotelischen Leitgedanken der Rechtsordnung und der politischen Freundschaft ansetzt und dabei sowohl die normative Dimension als auch den machtpolitischen Realismus dieser Uberlegungen angemessen wurdigt. Diese Arbeit wurde von der Osterreichischen Akademie der Wissenschaften im Jahr 2018 mit dem Bohlaupreis ausgezeichnet.

Political philosophy reduced man to a speaking being and forgot his old trade with nature. We discover back this trade, as a political object, an issue for militancy, and we don’t believe any longer in mankind power.

Dieser Text beschreibt die besondere Existenzweise und Operationalität des Rechts, das nicht von externen sozialen Faktoren determiniert wird, dessen Autonomie aber auch nicht die eines Subsystems ist. Was es in seiner absichtsvollen Oberflächlichkeit leisten kann, ist eine besondere Form der Verbindung: Seine Enunziationsform verknüpft alle Äußerungen und Handlungen so, dass sie eindeutig einem Sprechenden und Handelnden zugeordnet werden können: Dies ist der ununterbrochene Faden, mit dem es Menschen, Güter, Orte, Zeit, Beschlüsse etc. zusammenhält. The text describes the specific mode of (...) existence and operation of Law, which is not determined by external social factors, nor is its autonomy that of a subsystem. Its deliberate super ciality achieves a particular form of cohesion: Its form of enunciation connects utterances and actions in such a way that they can be assigned unambiguously to a single speaker and actor. This is the undisrupted thread which binds men, goods, locations, time, resolutions, etc. (shrink)

James Lovelock n'a pas eu de chance avec l'hypothèse Gaïa. En nommant par ce vieux mythe grec le système fragile et complexe par lequel les phénomènes vivants modifient la Terre, on a cru qu'il parlait d'un organisme unique, d'un thermostat géant, voire d'une Providence divine. Rien n'était plus éloigné de sa tentative. Gaïa n'est pas le Globe, n'est pas la Terre-Mère, n'est pas une déesse païenne, mais elle n'est pas non plus la Nature, telle qu'on l'imagine depuis le XVIIe siècle, (...) cette Nature qui sert de pendant à la subjectivité humaine. La Nature constituait l'arrière-plan de nos actions. Or, à cause des effets imprévus de l'histoire humaine, ce que nous regroupions sous le nom de Nature quitte l'arrière-plan et monte sur scène. L'air, les océans, les glaciers, le climat, les sols, tout ce que nous avons rendu instable, interagit avec nous. Nous sommes entrés dans la géohistoire. C'est l'époque de l'Anthropocène. Avec le risque d'une guerre de tous contre tous. L'ancienne Nature disparaît et laisse la place à un être dont il est difficile de prévoir les manifestations. Cet être, loin d'être stable et rassurant, semble constitué d'un ensemble de boucles de rétroactions en perpétuel bouleversement. Gaïa est le nom qui lui convient le mieux. En explorant les mille figures de Gaïa, on peut déplier tout ce que la notion de Nature avait confondu : une éthique, une politique, une étrange conception des sciences et, surtout, une économie et même une théologie. (shrink)

Let's touch base -- Relocalizing the global -- Without the world or within -- Sharing responsibility: farewell to the sublime -- From lands to disputed territories -- Innovation not hype -- Secular at last -- In search of a diplomatic middle ground -- Appendix.