Human–nonhuman chimeras have been the focus of ethical controversies for more than a decade, yet some related issues remain unaddressed. For example, little has been said about the relationship between the origin of transferred cells and the morally relevant capacities to which they may give rise. Consider, for example, a developing mouse fetus that receives a brain stem cell transplant from a human and another that receives a brain stem cell transplant from a dolphin. If both chimeras acquire morally relevant (...) capacities as a result of transplantation, and if those capacities are indistinguishable, should the difference in cell origin matter to how we classify these creatures? I argue that if morally relevant capacities are easy to detect, cell origin is irrelevant to how the chimera ought to be treated. However, if such capacities are hard to detect, cell origin should play a role in considerations about how to treat the chimera. (shrink)

Die Unverzichtbarkeit der Beratung bzw. Prüfung einer medizinischen Studie durch eine Ethikkommission ist weithin anerkannt. Dennoch sind Forschungsethikkommissionen immer wieder der Kritik, z.B. nach mehr Effizienz, Transparenz oder Konsistenz ausgesetzt. Evaluationsinstrumente für Ethikkommissionen beinhalten oft implizite Vorstellungen „guter“ Qualität. Aus ethischer Sicht sind vor allem der Schutz der Versuchsperson und eine vertretbare Schaden-Nutzen-Bewertung wichtig. Der interdisziplinäre Sammelband geht der Frage auf den Grund, wie sich eine Qualitätsverbesserung aus ethischer Sicht gewährleisten und umsetzen lässt. Der Inhalt · Ethikkommissionen im rechtlichen und (...) ethischen Diskurs · Rechtliche Rahmenbedingungen von Ethikkommissionen in der Schweiz und organisatorische und prozedurale Qualitätskriterien · Forschungs-Ethikkommissionen in der Schweiz: Qualitätsbewertung aus ethischer Sicht · Ethikkommissionen als Patientenschutzkommissionen · Die ethische Aufgabe von Ethikkommissionen angesichts normativer Divergenz von Therapie und Forschung · Ethische Theorien und die Bewertung von Forschungsvorhaben · Kriterien für die ethische Qualität des Begutachtungsprozesses · Schutz der Versuchsperson: Forderungen aus ethischer Sicht zur Struktur-, Prozess- und Ergebnisqualität Die Herausgeber Prof. Dr. Monika Bobbert lehrt und forscht zur Moraltheologie und Medizinethik an der Universität Münster. Dr. Gregor Scherzinger ist wissenschaftlicher Mitarbeiter am Institut für Sozialethik der Universität Luzern. (shrink)

Humans have a fundamental need to belong. This, need, as Kimberley Brownlee argues in her book Being Sure of Each Other grounds the human right against social deprivation. But in addition to having a human right against social deprivation, we also have a right to associational freedom, which is grounded in our right to autonomy. We cannot be forced into relationships; we are free to choose our friends and loved ones.? In this paper I discuss what our right to associational (...) freedom morally permits us to do when are already in an intimate relationship and, relatedly, what our relationship-dependent duties require of us in such cases. What exactly are the constraints on our right to associational freedom? And what is the content and scope of our relationship-dependent duties, given that our right to associational freedom conflicts with the fulfillment of these duties?? After providing some clarifications as to how we should understand intimate relationships that have ended, I will first highlight what relationship-dependent duties are and how they correlate with a right to associational control. I will then discuss several break-up scenarios, the aim of which is to determine the conditions that justify constraints being imposed on the right to associational freedom and to delineate the scope of relationship-dependent duties. (shrink)

The concept of the dialogical soul proposed by Joseph Ratzinger is a contemporary attempt to describe the anthropology of humanity in terms of basic, fundamental theological concepts. Epistemological approach of the dialogic soul is not about the division, but co-existence in the concept of humanity significantly different anthropological concepts. Modern neuroscience, although following completely different paths of knowing is currently concerning an important issue "of the embodied mind". Such a holistic effort to discover the truth about the man, though carried (...) out on completely different epistemological platforms, however, have some points in common. The difficulty in finding a common language for the dialogue in this field can be overcome and lead to dialogue, which is extremely difficult but doable. We must, however, at the beginning formulate certain fundamental axioms that define class concepts used in different areas of scientific activity. The concept of dialogical soul of Ratzinger’s now exceeds the barrier of scientific paradigms axioms. It does not stop on the vision of human oneself, but recognition of one in the area of relationships and makes room for a substantial dialogue with the world of modern science. (shrink)

Comparative genomicists seem to be convinced that the unit of measurement employed in their studies is a gene that drives the function of cells and ultimately organisms. As a result, they have come to some substantive conclusions about how similar humans are to other organisms based on the percentage of genetic makeup they share. I argue that the actual unit of measurement employed in the studies corresponds to a structural rather than a functional gene concept, thus rendering many of the (...) implications drawn from comparative genomic studies largely unwarranted, if not completely mistaken. †To contact the author, please write to: Department of Philosophy, University of Utah, 215 South Central Campus Drive, Carolyn Tanner Irish Humanities Building, 4th Floor, Salt Lake City, UT 84112; e‐mail: monika[email protected]. (shrink)

The west-centrism in approaching the knowledge systems of east has been sufficiently highlighted and problematized. This paper argues that the attempts have often been restricted to a framework of colonial gaze that prevents the Indian classical philosophy from gaining a vantage of its own. The approach to the classical traditions have been largely fragmented, catering to the pressure of proving its “relevance” either as a knowledge system or as texts with useful resources and answers to contemporary problems. This “problem solving” (...) framework at the very outset de-recognizes the capacity of an entire philosophical tradition of problem identification and formulation, unsettling terrains of knowledge by asking new questions. The article presents a case for theorizing relevance as a prerequisite to resolving some of these issues. (shrink)

This interdisciplinary, social scientific analysis of the regulatory discourse on nanotechnology in the three German-speaking countries of Germany, Austria and Switzerland and in the EU between 2000 and 2013 has shown three distinct phases, characterised by shifts in the configuration of actors and in the thematic scope from nanotechnology to nano-materials. Compared to modes of governance based on traditional statutory law, modes of governance based on less binding forms of soft law and self-regulation (like codes of conduct, guidelines and certification (...) systems) and new modes of governance (like assessment studies, risk management frameworks as well as participatory and cooperative forms of communication and negotiation) have gained importance. Despite some similarities, two different cultures in governing nanotechnology can be distinguished: a product-oriented culture in statutory regulations (when speaking about products, the article is also referring to substances) and a risk-based culture in applying soft law based on new modes of governance. In addition, the different regulatory cultures have led to four strategic approaches: modes of governance mainly based on hard law and soft law at the EU level, modes of governance mainly based on cooperative and self-regulatory approaches in Germany, cooperative governance approaches in Austria and modes of governance mainly based on self-regulatory and soft law approaches in Switzerland. (shrink)

According to Haber and Benham (2012), a sufficient condition for full moral consideration is that a creature bears a genealogical relation to the Homo sapiens lineage. Since part-humans do not bear such a relation, they are not due full moral consideration on that basis. Given this argument, my aim in this commentary is twofold. First, I want to challenge its soundness by showing that it is possible for part-humans to bear a genealogical relation to the H. sapiens lineage. Second, I (...) want to argue that Haber and Benham's attempt at avoiding moral confusion by reframing ethical concerns about part-humans doesn’t work. (shrink)

Extrapolation from a well-understood base population to a less-understood target population can fail if the base and target populations are not sufficiently similar. Differences between laboratory mice and humans, for example, can hinder extrapolation in medical research. Mice that carry a partial or complete human physiological system, known as humanized mice, are supposed to make extrapolation more reliable by simulating a variety of human diseases. But what justifies our belief that these mice are similar enough to their human counterparts to (...) simulate human disease? I argue that, unless three requirements are met in the process of humanizing mice, very little does. My requirements are not meant to provide necessary and sufficient conditions that guarantee a particular outcome. Instead, they serve as a heuristic for guiding scientific judgments involving extrapolation. In developing each requirement, I engage with philosophical issues concerning the nature of model-based science and the mechanistic approach (and its limits) to making generalizations in the life sciences. (shrink)

This article analyses the patterns underlying debates in sociological theory, using the debate surrounding the distinction between ‘micro’ and ‘macro’ as its case. Although – and indeed because – few authors have attempted explicit definition of the distinction, a number of different distinctions have been subsumed under these labels and research has been shaped by packages of assumptions that have gone largely unexamined in their contradictory nature. The article disaggregates the different distinctions that have been associated with the terms ‘micro’ (...) and ‘macro’ and situates theoretical strategies of the past decades in the grammar of oppositions that makes them possible and innovative. Gap-bridging has been the attempt to bring together aspects of the distinction that have been construed as direct opposites; recombination has been the attempt to release certain aspects of the distinction from their association with one side of the divide. Disaggregating the distinction can help us isolate specific theoretical problems for further work, including work that asks how aspects emphasized by different theoretical approaches vary empirically. (shrink)

In dieser Studie untersucht Monika Palowski das kontrovers diskutierte Phänomen der Klassenwiederholung erstmals aus Perspektive der Wissenssoziologischen Diskursanalyse. Anhand von insgesamt über 700 Texten aus Erziehungswissenschaft und Printmedien werden machtvolle Diskursstränge und -formationen rekonstruiert, die nicht nur die Wahrnehmung von Klassenwiederholung und schulischer Selektion, sondern auch der betroffenen Subjekte je spezifisch präfigurieren und dadurch Klassenwiederholung teils auch legitimieren. Die Ergebnisse der Analyse sind daher einerseits für die erziehungswissenschaftliche Auseinandersetzung mit schulischer Selektion und Bildungsungerechtigkeit relevant, andererseits aber auch für die (...) Diskurs- und Subjektivierungsforschung. (shrink)

Modalizmas, arba filosofinė teorija, teigianti, kad modalinės sąvokos, tokios kaip galima ir būtina, yra neredukuojamos ir neanalizuojamos, reikšmingai skiriasi nuo galimų pasaulių semantikos, kur modalinės sąvokos interpretuojamos kaip galimų pasaulių kvantifikavimas. Straipsnyje nagrinėjami pagrindiniai modalizmo principai, remiantis šią teoriją plėtojusių Arthuro Prioro, Kito Fine’o ir Graeme’o Forbeso darbais. Tuomet aptariama tokių mąstytojų kaip Davidas Lewisas, kuris teigia, kad antireduktyvizmas modalumų atžvilgiu apskritai nelaikytinas teorine prieiga, bei Josephas Melia, kuris tvirtina, jog modalizmas implicitiškai mėgdžioja galimų pasaulių semantiką, kritika. Straipsnyje įrodinėjama, kad (...) formali modalizmo kalba grindžiama ne kuo kitu, kaip natūralia kalba, ir kad modalizmas nesiremia galimų pasaulių semantika. Be to, pabrėžiama, kad modalizmas siūlo intuityvesnį modalinių sąvokų supratimą, lyginant su galimų pasaulių semantika. (shrink)

The concept of vulnerability is widely used in human rights policy documents, reports, and case law focusing on the impacts of climate change on human rights. In academic discussions, the concept, however, has also sparked a discussion on its benefits and challenges for the advancement of human rights, especially concerning the principles of equality and non-discrimination. This article aims at contributing to this debate from a frame-analytical perspective. In social sciences, frame-analysis is a form of discourse analysis which focuses on (...) the consequences of different concepts for legal, political, and social discussions and norms. With the example of selected UN documents on different human rights issues in the context of climate change, the article, firstly, analyzes whether and how the concept of vulnerability is defined in the documents and why it is used in the documents. Secondly, it is elaborated to which individuals and groups the concept is applied. Thirdly, it is discussed how vulnerability is conceptualized in relation to or in distinction to the concepts of inequality and discrimination. In a further section it is analyzed what narratives are mobilized by the frame of vulnerability. The article concludes that from a discourse-analytical perspective the frame of vulnerability mobilizes problematic narratives which has gendered and racialized implications for those labeled vulnerable. (shrink)

This paper argues that critical realism is one of the main theoretical orientations of the social sciences in the twentieth and twenty-first centuries. Critical realism aims to study the transcende...

The current study investigated age differences in the use of attentional deployment, positive reappraisal and suppression while regulating responses to sadness-eliciting content. We also tested to what extent these emotion regulation strategies were useful for each age group in managing response to age-relevant sad information. Forty-two young participants (Mage = 18.5, SE =.15) and 48 older participants (Mage = 71.42, SE = 1.15) watched four sadness-eliciting videos (about death/illness, four to five minutes long) under four conditions—no-regulation (no regulation instructions), attentional (...) deployment (divert attention away), positive reappraisal (focus on positive outcomes) and suppression (conceal emotional expressions). We assessed negative emotional experience, expression, skin conductance level (SCL) and visual fixation duration while participants watched the emotional clips and followed the instructions for each condition. Results suggest that older adults were more successful than younger adults at implementing both attentional deployment and positive reappraisal. Ability to suppress emotions appears to remain stable with age. Within age-group comparisons suggested that for the older adults, positive reappraisal was a more useful emotion regulation strategy than the others, while the pattern among younger adults was less conclusive. Age-relevant differences in motivation and successful emotion regulatory efforts based on theoretical and empirical literatures are discussed. (shrink)

The article will attempt a reading of Alan Spence’s play No Nothing. Special attention will be given to the issue of literal and metaphorical space, a peculiar, liminal setting of the play, and the ways it determines the flyting between the two characters, two iconic Glaswegians: Edwin Morgan and Jimmy Reid. It seems that in this theatrical space history, politics and poetry inter-are. We may notice how two completely different masters of speech exchange their views on life, how they reflect (...) upon the meaning of their achievements, and how they find a space of convergence in their affirmation of life. As their flyting is “about life, the Universe and everything—from Glasgow to Infinity and beyond,” the article will also address the space of dialogue between Spence’s and Morgan’s poetry. The metaphor of Indra’s net will serve as a useful tool in exploring spatial dimensions of the play and the issue of interconnectedness. (shrink)

Greek philosophy, especially Aristotelianism, because of the concept of God present in this thought, did not raise the issue of divine omniscience and divine knowledge of evil. The divine omnisciene seemed to be contrary to God’s perfect being. In the time of Themistius, whose thought I present in this paper, Neoplatonism and Christian Neoplatonism showed new possibilities of solving this problem. Themistius being aware of these new topics and including them in his own philosophy, still however represents ancient Aristotelianism with (...) all its limitations. He asked about divine knowlegde of evil, but in his answer he repeated only the Aristotelian doctrine: God knows only Himself, because He Himself is the most perfect object of knowledge and cannot know less perfect beings. (shrink)

In this paper I focus on the Hungarian intellectual and politician Paul Szende’s sociologically oriented epistemology. I trace the influences of physiology, psychology, economy, evolutionary theory of his day on his sociological theory of abstractive knowledge, and discuss the close connection between physiological, social, and economic aspects in the early sociology of knowledge. My discussion continues with an examination of Szende’s differentiation between two economic effects within social epistemology: on the one hand the ‘economy of thought’ in the tradition of (...) Ernst Mach, with its physiological, organic, and integrative functioning of knowledge; on the other hand, the socio-economic effects of social selection, exclusion, and societal antagonism. Besides the Marxist and more specifically the Austro-Marxist environment of Szende’s writings, I trace the influence of the economic theory of Italian economist Achille Loria on Szende’s understanding of the antagonistic nature of the transformation of knowledge. The paper is set at the intersection of philosophy of science and history of science. It relates epistemological issues to historical, social, and scientific developments in Szende’s day and thus combines a philosophical analysis of Szende’s sociological theory of knowledge with historical research into the natural, social, and economic sciences of his time. (shrink)

What’s the basis for considering an egg donor a genetic parent but not a mitochondrial donor? I will argue that a closer look at the biological facts will not give us an answer to this question because the process by which one becomes a genetic parent, i.e., the process of reproduction, is not a concept that can be settled by looking. It is, rather, a concept in need of philosophical attention. The details of my argument will rest on recent developments (...) in biological technology, but the persuasiveness of my argument will turn on the history of another biological concept, death. Given some important similarities between the two concepts, the way in which ‘death’ evolved in the recent past can provide guidance on how we should think about ‘reproduction.’. (shrink)

I am grateful to the authors who commented on my article (Piotrowska 2014) for their careful examination of my argument. They have presented a variety of stimulating ideas and suggestions, with which I largely agree and which I would like to discuss further, but in the interest of brevity, I shall try to concentrate only on points of contention.

In the digital age, the use of advanced technology is becoming a new paradigm in police work, criminal justice, and the penal system. Algorithms promise to predict delinquent behaviour, identify potentially dangerous persons, and support crime investigation. Algorithm-based applications are often deployed in this context, laying the groundwork for a ‘smart criminal justice’. In this qualitative study based on 32 interviews with criminal justice and police officials, we explore the reasons why and extent to which such a smart criminal justice (...) system has already been established in Switzerland, and the benefits perceived by users. Drawing upon this research, we address the spread, application, technical background, institutional implementation, and psychological aspects of the use of algorithms in the criminal justice system. We find that the Swiss criminal justice system is already significantly shaped by algorithms, a change motivated by political expectations and demands for efficiency. Until now, algorithms have only been used at a low level of automation and technical complexity and the levels of benefit perceived vary. This study also identifies the need for critical evaluation and research-based optimization of the implementation of advanced technology. Societal implications, as well as the legal foundations of the use of algorithms, are often insufficiently taken into account. By discussing the main challenges to and issues with algorithm use in this field, this work lays the foundation for further research and debate regarding how to guarantee that ‘smart’ criminal justice is actually carried out smartly. (shrink)