Die traditionsreiche Reihe QUELLEN UND FORSCHUNGEN ZUR LITERATUR- UND KULTURGESCHICHTE, deren Ursprung auf das Jahr 1874 zur ckgeht, geh rt zum festen Bestand renommierter Publikationsforen der Deutschen Literaturwissenschaft. Von Ernst Osterkamp und Werner R cke an der Humboldt-Universit t zu Berlin herausgegeben, pr sentieren die QUELLEN UND FORSCHUNGEN hochwertige wissenschaftliche Arbeiten, die literarische Texte im Zusammenhang mit kulturhistorischen Ph nomenen, besonders auch mit den anderen K nsten, untersuchen. Philologische Studien mit transdisziplin rem Ansatz sind ausdr cklich erw nscht. Der Schwerpunkt (...) der Serie liegt auf der deutschen Literatur vom Mittelalter bis in die Gegenwart. Da die kulturgeschichtliche Ausrichtung der Reihe Aspekte interkultureller Erfahrung und nationaler Fremdwahrnehmung einbegreift, stehen die QUELLEN UND FORSCHUNGEN im Einzelfall aber auch komparatistischen Arbeiten offen. Ver ffentlicht werden Monographien, Dissertationen und Habilitationsschriften sowie thematisch geschlossene Sammelb nde. Die Ma st be f r die Aufnahme in die Reihe bilden wissenschaftliche Relevanz und Exzellenz in Methode und Darstellung. (shrink)

The International Agency for Research on Cancer (IARC) is an organization which seeks to identify the causes of human cancer. Per agent, such as betel quid or Human Papillomaviruses, they review the available evidence deriving from epidemiological studies, animal experiments and information about mechanisms (and other data). The evidence of the different groups is combined such that an overall assessment of the carcinogenicity of the agent in question is obtained. In this paper, we critically review the IARC’s carcinogenicity evaluations. First (...) we show that serious objections can be raised against their criteria and procedures – more specifically regarding the role of mechanistic knowledge in establishing causal claims. Our arguments are based on the problem of confounders, of the assessment of the temporal stability of carcinogenic relations, and of the extrapolation from animal experiments. Then we address a very important question, viz. how we should treat the carcinogenicity evaluations that were based on the current procedures. After showing that this question is important, we argue that an overall dismissal of the current evaluations would be too radical. Instead, we argue in favour of a stepwise re-evaluation of the current findings. (shrink)

Whereas Pettit distinguishes between responsibility for the enactment of a directly harmful act and responsibility for the arrangement or constitution that channels the formation of a corporate agent’s beliefs, desires, and intentions, we should acknowledge the existence of yet a third level of responsibility: the enactment of corporate arrangements that makes the enactment of harmful corporate actions likely or unavoidable.

Teksten, beschouwingen en biografische gegevens van en over de vrijdenker, humanist en Multatulikenner Piet Spigt (1919-1990).

Introduction. Bert HAMMINGA and Neil DE MARCHI: Préface. Bert HAMMINGA and Neil DE MARCHI: Idealization and the Defence of Economics: Notes Toward a History. Part I: General Observations on Idealization in Economics. Kevin D. HOOVER: Six Queries about Idealization in an Empirical Context. Bernard WALLISER: Three Generalization Processes for Economic Models. Steven COOK and David HENDRY: The Theory of Reduction in Econometrics. Maarten C.W. JANSSEN: Economic Models and Their Applications. Adolfo GARCÍA DE LA SIENRA: Idealization and Empirical Adequacy (...) in Economic Theory. Izabella NOWAKOWA and Leszek NOWAK: On Correspondence between Economic Theories. Uskali MÄKI: Isolation, Idealization and Truth in Economics. Part II: Case Studies of Idealization in Economics. Nancy CARTWRIGHT: Mill and Menger: Ideal Elements and Stable Tendencies. Wolfgang BALZER: Exchange Versus Influence: A Case of Idealization. Kees COOLS, Bert HAMMINGA, Theo A.F. KUIPERS: Truth Approximation by Concretization in Capital Structure Theory. Daniel M. HAUSMAN: Paul Samuelson as Dr. Frankenstein: When an Idealization Runs Amuck. Hugo A. KEUZENKAMP: What if an Idealization is Problematic? The Case of the Homogeneity Condition in Consumer Demand. Werner DIEDERICH: Nowak on Explanation and Idealization in Marx's 'Capital'. Gérard JORLAND: Idealization and Transformation. Jack BIRNER: Idealizations and Theory Development in Economics. Some History and Logic of the Logic Discovery. Discussions. Leszek NOWAK: The Idealizational Methodology and Economics. Replies to Diederich, Hoover, Janssen, Jorland and Mäki. (shrink)

The impressive young scholar Bert Mosselmans, analyzing the theory and policy of Jevons, a major figure in the field of the history of economics, has put together a volume with broad international appeal, particularly in Europe, North America and Japan, that offers a synthetic approach to Jevons’ economic theory, applied economics and economic policy. Adopting a relativist approach to his subject, Mosselmans focuses on all aspects of Jevons’ theory, tying the different strands together where appropriate and discriminating where necessary. (...) Examining the relation between theory and practise he situates Jevons within the history of economic thought and in relation to his logic, ethics, religion and aesthetics. Ideal for scholars working in the fields of philosophy and history as well as economics, this ambitious and insightful work offers a comprehensive analysis of one of the founding fathers of modern economic thought, whose work marked a new chapter in its history, bridging the gap between classical and neo-classical economics. (shrink)

The volume contributes to the ongoing nanoethics debate in four topical areas. The first part tackles questions of what could be called ‘meta-nanoethics’. Its focus lies on basic concepts and the issue of what - if anything - is truly novel and special about the new field of nanoethics or its subject matter. The second part of this volume presents a selection of interesting perspectives on some of the opportunities and challenges of nanotechnology. Part three takes a more in depth (...) look at one of the most pressing current concerns: how to deal with the risks and uncertainties surrounding nanotechnology in a responsible manner. In its fourth and final part the volume touches on issues of public debate and policy. (shrink)

If one compares the development of modern medical ethics in Germany with those in the Netherlands, what stands out are the cultural and intellectual differences between the two countries. Dealing with the problems involved in limiting medical treatment, the authors show the differing and the common standards and values on which the discussion of this is based in both countries. Three examples, active termination of life, the do-not-resuscitate order and pain management, which are examined from an historical, legal, philosophical and (...) ethical perspective, put this in concrete terms. The authors belong to different generations as well as different political and philosophical camps. Vergleicht man die Entwicklung der modernen Medizinethik in Deutschland mit jener in den Niederlanden, fallen die kulturellen und intellektuellen Unterschiede zwischen beiden Landern deutlich auf. Anhand der Problematik der Begrenzung medizinischen Handelns zeigen die Autoren die verschiedenen bzw. gemeinsamen Normen und Werte, die der Diskussion daruber in beiden Landern zugrunde liegen. Drei Beispiele, die aktive Lebensbeendigung, die Nicht-Reanimierung und die Schmerzbekampfung, die aus historischem, juristischem, philosophischem und ethischem Blickwinkel betrachtet werden, konkretisieren die Darstellung. Die Autoren gehoren unterschiedlichen Generationen, politischen und lebensanschaulichen Lagern an. (shrink)

In the traditional African view, words and sentences are not viewed as being liable to objective reflective truth/falsehood-judgments. It is not a person-word-reality-view, but a person-word-person-view: the sender's words are units of orally produced energy that have the power to improve or degenerate the receiver's vitality. Words received can make you more powerful by increasing your confidence and your control over your environment. But they can equally well harm (parts of) you, by discouraging you in certain endeavors. From the traditional (...) African point of view, words are not logical, but physical phenomena: words are forces affecting power. (shrink)

This collection of philosophical essays addresses important issues in the arts, encompassing painting, sculpture, photography, film and architecture.

monsters, virtual legends such as 2001’s HAL or Demon Seed’s Proteus are actually scary because of their mind. Without lingering on the philosophical debates on whether a certain type of mind can exist independent of its specific embodiment or whether any creature can understand a consciousness that is not like his own (recall Lem’s Solaris), the thing that makes HAL and Proteus so human is not so much their ability to think as their possessing something resembling human consciousness. The point (...) is that, whereas consciousness may or may not be required for an artificial agent to think, it is an essential element in creating anything resembling a human-like thinker that would pass the Turing Test. (shrink)

A significant part of everyday learning occurs incidentally — a process typically described as implicit learning. A central issue in this and germane domains such as language acquisition is the extent to which performance depends on the acquisition and deployment of abstract rules. In an attempt to address this question, we show that the apparent use of such rules in a simple categorisation task of artificial grammar strings, as reported by Shanks, Johnstone, and Staggs (1997), can be simulated by means (...) of a simple recurrent network, and may thus turn out not be incompatible with the acquisition of statistical regularities rooted in the processing of exemplars of the presented material. (shrink)

This book discusses issues regarding conceptualization, governance and implementation of responsible innovation. It treats different approaches to making responsible innovation a reality and it contains new case studies that illustrate challenges and solutions. Research on Responsible Innovation is by its nature highly multidisciplinary, and also pro-active, design-oriented and policy-relevant. Until a few years back, the concept of Responsible Innovation was hardly used - nowadays it is increasingly receiving attention from both researchers and policy makers. This is indispensable reading for anyone (...) interested in or working on innovation. (shrink)

In the traditional African view, knowledge is not acquired by labor but "given" by the ancestors. Second, it is immediately social: not "I" know, but "we" know. Thirdly, knowledge is not universal but local tribal : other tribes have different knowledge. Knowledge has it "biological variations" like all other things in nature. The ensuing logic is worked out in this article. Modern African society, changed as it is by the advent of western thought, should be understood in the awareness of (...) the conflicting nature of the two ideas of knowledge. (shrink)

The field of medicine is generally greeted with great enthusiasm. This can be witnessed in the immense support for medical progress, which is widely hoped to lead to a realization of idealized goals. Indeed, with the help of medicine the human body would be controllable and constructible, human nature perfectible. However, enthusiasm in favor of medical progress is first and foremost a sentiment and, like all sentiments, not necessarily a product of rational contemplation. People are capable of enthusing about the (...) realization of utopian notions, such as life without disease or with the perfect body, without requiring any concrete arguments to back them up. Enthusiasm alone is not a guarantee of ethical desirability, however. Hence, this book takes a closer look at four research fields often referred to in medical utopian literature: 'tissue engineering', 'bioelectronics', 'germ line genome modification' and 'interventions in the biological aging process'. They serve as a basis for analyzing whether ethical arguments can be found to support the euphoric advocacy of the further development of these fields. (shrink)

In spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could —paradoxically— be seen as representing the ‘dark matter’ of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations, which allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in (...) interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really go social; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition. (shrink)

Today, mechanisms and mechanistic explanation are very popular in philosophy of science and are deemed a welcome alternative to laws of nature and deductive‐nomological explanation. Starting from Mitchell's pragmatic notion of laws, I cast doubt on their status as a genuine alternative. I argue that (1) all complex‐systems mechanisms ontologically must rely on stable regularities, while (2) the reverse need not hold. Analogously, (3) models of mechanisms must incorporate pragmatic laws, while (4) such laws themselves need not always refer to (...) underlying mechanisms. Finally, I show that Mitchell's account is more encompassing than the mechanistic account *Received August 2008; revised January 2010. †To contact the author, please write to: Centre for Logic and Philosophy of Science, Ghent University, Blandijnberg 2, B‐9000 Belgium; e‐mail: Bert[email protected]. (shrink)

Opinions are rarely binary; they can be held with different degrees of conviction, and this expanded attitude spectrum can affect the influence one opinion has on others. Our goal is to understand how different aspects of influence lead to recognizable spatio-temporal patterns of opinions and their strengths. To do this, we introduce a stochastic spatial agent-based model of opinion dynamics that includes a spectrum of opinion strengths and various possible rules for how the opinion strength of one individual affects the (...) influence that this individual has on others. Through simulations, we find that even a small amount of amplification of opinion strength through interaction with like-minded neighbors can tip the scales in favor of polarization and deadlock. (shrink)

L’histoire récente des sciences humaines et sociales commence à prendre en considération la question des représentations de la vie savante par les savants eux mêmes, comme de la manière dont il parle et commente leur propre travail de recherche. Georges Dumézil donne à voir un parcours très intéressant, faits de multiples repentirs et tâtonnements que Dumézil intégra au cœur de sa méthode comparative.

The use of coercion is morally problematic and requires an ongoing critical reflection. We wondered if not knowing or being uncertain whether coercion is morally right or justified (i.e. experiencing moral dou...

Commemorate[s] the centennial of the meeting of the Linnean Society, July 1, 1858, and the paper of Charles Darwin and Alfred Russel Wallace which were read there.

The Transformation of Learning gives an overview of some significant advances of the cultural-historical activity theory, also known as CHAT in the educational domain. Developments are described with respect to both the theoretical framework and research. The book's main focus is on the evolution of the learning concept and school practices under the influence of cultural-historical activity theory. Activity theory has contributed to this transformation of views on learning, both conceptually and practically. It has provided us with a useful approach (...) to the understanding of learning in cultural contexts. (shrink)

The present paper is a reading of Jean-Pierre Jeunet’s recent film, A Very Long Engagement, mainly through the lenses of Jacques Lacan’s psychoanalytical theory of the human subject—particularly his notion of the subject’s desire, which constitutes every human subject as a singular being. Moreover, for Lacan the subject faces the task of taking up his or her desire as a prerequisite for truly ethical action. The character of Mathilde in Jeunet’s film, it is argued, may be seen as being paradigmatic (...) in this respect, insofar as she acts in accordance with her desire. This is demonstrated with reference to the narrative structure of Jeunet’s film. (shrink)

In this article, I present two conceptual problems for Craver's mutual manipulability account of constitutive relevance in mechanisms. First, constitutive relevance threatens to imply causal relevance despite Craver (and Bechtel)'s claim that they are strictly distinct. Second, if (as is intuitively appealing) parthood is defined in terms of spatio-temporal inclusion, then the mutual manipulability account is prone to counterexamples, as I show by a case of endosymbiosis. I also present a methodological problem (a case of experimental underdetermination) and formulate two (...) partial, but fallible solutions based on the notions of parthood and synchronicity. (shrink)