With vast new scientific and technological powers, we face unprecedented choices for which traditional ethics provide little direct guidance. What role can the religious community play in addressing the ethical and theological issues that even science now acknowledges as urgent?Chapman's work forges a method for integrating ethical reasoning with scientific data, focusing on four issues -- cloning, genetic engineering, patenting of life, and environmental alteration. For each, she reviews the work of religious thinkers, assesses the roles of the religious community, (...) considers relevant confessional differences, determines how traditional theological and ethical concepts can be clarified, reformulated, and "operationalized" to meet the questions, and finally she formulates helpful methodological options. She calls for a scientifically informed religious ethics built dialogically from concepts in both science and theology. (shrink)

There are two general questions which many views in the philosophy of mathematics can be seen as addressing: what are mathematical objects, and how do we have knowledge of them? Naturally, the answers given to these questions are linked, since whatever account we give of how we have knowledge of mathematical objects surely has to take into account what sorts of things we claim they are; conversely, whatever account we give of the nature of mathematical objects must be accompanied by (...) a corresponding account of how it is that we acquire knowledge of those objects. The connection between these problems results in what is often called "Benacerraf's Problem", which is a dilemma that many philosophical views about mathematical objects face. It will be my goal here to present a view, attributed to Richard Dedekind, which approaches the initial questions in a different way than many other philosophical views do, and in doing so, avoids the dilemma given by Benacerraf's problem. (shrink)

The logical empiricists often appear as a foil for feminist theories. Their emphasis on the individualistic nature of knowledge and on the value-neutrality of science seems directly opposed to most feminist concerns. However, several recent works have highlighted aspects of Carnap's views that make him seem like much less of a straightforwardly positivist thinker. Certain of these aspects lend themselves to feminist concerns much more than the stereotypical picture would imply.

Audrey Rousseau La recherche de formes de rétablissement à la suite d’événements difficiles, voire traumatiques, implique souvent de considérer la parole comme un moteur de transformation personnelle et sociale. À partir de préoccupations éthiques et épistémologiques d’une chercheuse non autochtone menant une recherche collaborative au sujet des disparitions et des assassinats de femmes et de filles autochtones en Abitibi-Témiscamingue, cet article interroge plus précisément l’association fréquente entre l’expression du souvenir et la recherche d’un « mieux-être ». Après avoir introduit (...) les assises de cette recherche, qui se fonde sur l’oralité comme mode de transmission des savoirs entre générations, j’explorerai certaines conceptions du mieux-être et de la guérison tirées de la littérature scientifique autochtone. Puis, à partir du postulat relationnel au fondement du pouvoir du storytelling chez les Premières Nations, je révélerai deux conceptions des récits-histoires : l’une les concevant comme des « médecines » qui rassemblent les forces des ancêtres, l’autre les traitant comme des enseignements valorisant l’identité culturelle et les savoirs traditionnels. En terminant, j’aborderai certaines tensions relatives à la volonté d’éclairer des problèmes complexes, tout en réfléchissant aux conditions de l’écoute de ces récits-histoires et aux défis de représenter et d’interpréter ces savoirs expérientiels. (shrink)

This is a paper about model-building and overfitting in normative ethics. Overfitting is recognized as a methodological error in modeling in the philosophy of science and scientific practice, but this concern has not been brought to bear on the practice of normative ethics. I first argue that moral inquiry shares similarities with scientific inquiry in that both may productively rely on model-building, and, as such, overfitting worries should apply to both fields. I then offer a diagnosis of the problems of (...) overfitting in moral inquiry and explain how our current practice seems worryingly susceptible to such problems. I conclude by giving suggestions for how we might avoid overfitting when doing normative ethics. (shrink)

Open Access: This paper will connect literature on epistemic injustice with literature on victims and perpetrators, to argue that in addition to considering the credibility deficit suffered by many victims, we should also consider the credibility excess accorded to many perpetrators. Epistemic injustice, as discussed by Miranda Fricker, considers ways in which someone might be wronged in their capacity as a knower. Testimonial injustice occurs when there is a credibility deficit as a result of identity-prejudicial stereotypes. However, criticisms of Fricker (...) have pointed out that credibility is part of a more complex system that includes both deficits and excesses. I will use these points to argue that we should look closer at sources of credibility excess in cases of sexual assault. This means that in addition to considering sources of victim blaming by looking at ways in which “ideal” victims are constructed, we also need to consider ways in which “ideal” perpetrators are constructed. (shrink)

This paper explores one of the major issues before transitional societies, the balance among truth, justice, and/or reconciliation. It focusses on the role of truth commissions, with an emphasis on the experience of South Africa. A central thesis of the paper is that establishing a shared truth that documents the causes, nature, and extent of severe and gross human rights abuses and/or collective violence under antecedent regimes is a prerequisite for achieving accountability, meaningful reconciliation, and a foundation for a common (...) future. It develops and applies an approach to reconciliation based on and extending Donald Shriver's concept of "political forgiveness.". (shrink)

BackgroundThis study explored the proportion of variance in depressive symptoms explained by processes targeted by BA (activation, behavioral avoidance, anticipatory pleasure, and brooding), and processes targeted by cognitive control training (cognitive control, attentional biases, and brooding).MethodsFive hundred and twenty adults were recruited. They completed a spatial cueing task as a measure of attentional biases and a cognitive task as a measure of cognitive control and completed self-report measures of activation, behavioral avoidance, anticipatory pleasure, brooding, and depressive symptoms. With path analysis (...) models, we explored the relationships between these predictors and depressive symptoms.ResultsBA processes were significant predictors of depressive symptoms, and activation partially predicted anticipatory pleasure, which in turn predicted depressive symptoms. However, cognitive control and attentional biases predicted neither brooding nor depressive symptoms. A comprehensive model including all processes fit the data but did not explain more of the variance in brooding or depressive symptoms than a model including only BA processes.LimitationsThe spatial cueing task was associated with low reliability and the use of a non-clinical sample limited the generalizability of the conclusions.ConclusionActivation, behavioral avoidance, brooding, and anticipatory pleasure are relevant processes to target in order to reduce depressive symptoms, while cognitive control and attentional biases are not. (shrink)

The logical empiricists often appear as a foil for feminist theories. Their emphasis on the individualistic nature of knowledge and on the value-neutrality of science seems directly opposed to most feminist concerns. However, several recent works have highlighted aspects of Carnap's views that make him seem like much less of a straightforwardly positivist thinker. Certain of these aspects lend themselves to feminist concerns much more than the stereotypical picture would imply.

Despite significant promotion of diversity in companies, as well as legislation for equal opportunities for women and men, it must be noted that women still remain largely in the minority in decision-making positions. This observation reflects the phenomenon of the glass ceiling that constitutes vertical discrimination within companies against women. Although the glass ceiling has generated research interest, some authors have pointed out that theoretical models have made little attempt to develop an understanding of this phenomenon and its implications. Therefore, (...) our study aims to fill this gap and to better understand the phenomenon of the glass ceiling by considering both its antecedents and its possible consequences. More precisely, we extend the model developed by Elacqua et al., proposing a more comprehensive model including organizational gender culture as a third factor in the emergence of the glass ceiling through the perception of differential treatment. We also investigated the glass ceiling’s consequences for organizational attitudes and well-being at work by considering work-to-family conflict as a possible mediator. We surveyed 320 women in managerial positions in a Belgian organization. Our study highlights the importance of all three factors in the emergence of the perception of differential treatment and, ultimately, the perception that a glass ceiling exists. Moreover, our results show that WFC fully mediates the effects of the glass ceiling on job strain and job engagement, and partially mediates the effects of the glass ceiling on job satisfaction and intention to quit. (shrink)

Globalization, a process characterized by the growing interdependence of the world's people, impacts health systems and the social determinants of health in ways that are detrimental to health equity. In a world in which there are few countervailing normative and policy approaches to the dominant neoliberal regime underpinning globalization, the human rights paradigm constitutes a widely shared foundation for challenging globalization's effects. The substantive rights enumerated in human rights instruments include the right to the highest attainable level of physical and (...) mental health and others that are relevant to the determinants of health. The rights stipulated in these documents impose extensive legal obligations on states that have ratified these documents and confer health entitlements on their residents. Human rights norms have also inspired civil society efforts to improve access to essential medicines and medical services, particularly for HIV/AIDS. Nevertheless, many factors reduce the potential counterweight human rights might exert, including and specifically the nature of the human rights approach, weak political commitments to promoting and protecting health rights on the part of some states and their lack of institutional and economic resources to do so. Global economic markets and the relative power of global economic institutions are also shrinking national policy space. This article reviews the potential contributions and limitations of human rights to achieving greater equity in shaping the social determinants of health. (shrink)

Many criticisms of epistemic logic have centered around its use of devices such as idealized knowers with logical omniscience and perfect self-knowledge. One possible response to such criticisms is to say that these idealizations are normative devices, and that epistemic logic tells us how agents ought to behave. This paper will take a different approach, treating epistemic logic as descriptive, and drawing the analogy between its formal models and idealized scientific models on that basis. Treating it as descriptive matches the (...) way in which some philosophers, including one of its founders, Jaako Hintikka, have thought about epistemic logic early in its history. Further, the analogy between the two fields will give us a way to defuse criticisms that see epistemic logic as unrealistic. For example, criticizing models of epistemic logic in which agents know all propositional tautologies as being unrealistic would be like criticizing frictionless planes in physics for being unrealistic. Each one would certainly be an unsuitable model for studying some kinds of phenomena, but is entirely appropriate for others. After outlining the analogy between epistemic and scientific models, we will discuss some ways in which idealizations are used by different research programs in epistemic logic. (shrink)

RésuméPartant de la considération inaugurale de.

In lieu of an abstract, here is a brief excerpt of the content:Body and Soul in the Philosophy of Plotinus AUDREY N. M. RICH BEFORE THE TIME Of Aristotle, there had been no serious philosophical enquiry into the relation existing between the body and the soul. Admittedly, in those Dialogues of Plato in which the problem of Motion begins to assume importance, something approaching a scientific interest in the question starts to emerge. In the Phaedrus, for instance, the soul (...) is considered as the source of all bodily movement and change,1 and in the Timaeus, the interaction of body and soul is given some attention and a special bodily organ allotted to each phase of the tripartite soul (69c-71a). But it is fair to say that on the whole, Plato does not give the impression of being vitally concerned about the soul-body relation. In fact, in the Phaedo, he makes it abundantly clear that he views such an association as morally regrettable rather than scientifically interesting; at this stage of his thought, he prefers, like Socrates, to ignore such questions as those discussed by Empedocles and Alcmaeon, namely, "whether we think with the blood, or whether it is the brain that is the seat of sensation" (96b). Thus, to some extent Plato merits the censure of Aristotle who, in the De Anirna (I:1,407b15-18), ranks him among those who "associate the soul with and place it in the body without specifying why this is so and how the body is conditioned." In Aristotle's opinion, examination of the soul-body connection is essential: "for it is by this association that the one acts and the other is acted upon, that the one moves and the other is moved; and no such mutual relation is found in haphazard combinations" (407b 18-21). Now there is a strong likelihood that Aristotle's criticism of Plato on this point may have led Plotinus to take up the problem to some extent neglected by his master. He must have known the De Anima, probably through the commentaries of Alexander of Aphrodisias which, we know, were read in his school along with the writings of other Peripatetics like Aspasius and Adrastus2; and although he did not himself envisage the soul-body relation in Aristotelian terms, nevertheless his whole enquiry into the subject is deeply colored by the language and influence of the De Anirna. Of course, Plotinus is much too loyal a Platonist to remain untouched by the dualism of the t245c-e; cp. Laws X: 898c5. ~Porphyry, Life of Plotinus, c. 15. [q 2 HISTORY OF PHILOSOPHY Phaedo, and the undertone of suspicion and hostility toward the body which is lacking in the De Anima but present in much of Plato, runs right through the Enneads of Plotinus. In fact, almost the last words of his final treatise on psychology reveal that this uneasy attitude persists to the end: "Life in the body," he says, "is in itself evil.''~ Strictly speaking, however, the extreme dualism of a Dialogue like the Phaedo has no real place in Plotinus' system. In his view, both body and soul are alike descended from the primal Absolute or One; each represents a different stage in the evolution of plurality from unity; soul is an earlier stage, body, a later; and though soul does not require body in order to exist, nevertheless, without body, it could never come forth fTom the intelligible realm to display its powers in the visible universe (IV: 3.9). Thus, because body is, in a sense, necessary to soul, because, figuratively speaking, it is the only "place" appropriate for the soul's occupation (IV: 3.9), it is impossible to view the relation between body and soul as one of unmitigated hostility. For to some extent, body and soul imply each other. On the cosmic level indeed, they never exist apart. For though we may speak of the "ensoulment" (~Ft~c0oLg) of the cosmos, because the cosmos is, in fact, eternal and uncreated, there never was a time when its soul and its body were dissociated (IV : 3.9). In the case of the human soul and body, however, matters are rather different, since it is evident that the two were separate... (shrink)

Context: Comparing the Covid-19 related experiences of vulnerable groups can help to improve public health.?The United States and the United Kingdom are both characterized by underfunded public health in the context of racist systems. We reviewed differences in Covid-19 outcomes between groups in the US and UK and compared intergroup differences between the two countries. Methods: The scoping review analyzed articles published in English during the Covid-19 pandemic focusing on the US or the UK. Using Scopus and PubMed, research articles (...) were chosen based on titles, abstracts, and relevance to the research question. Certain demographic groups known to be differentially affected by Covid-19 were chosen a priori for inclusion. Data was extracted by the first author and reviewed by senior authors. 63 studies met the inclusion criteria. Results: Two studies compared the US and UK. One found that minority status is an important social determinant of health (SDOH) of Covid-19 related health outcomes in both countries, likely through association with other SDOH. Another found that the risk of confirmed infection was higher in African-Americans, Hispanic Americans, and Asian Americans in the US and in African-Caribbean/Black-Africans, South-Asians, and Mixed-race people in the UK, compared with their respective White peers. Asian ethnicity is subject to different definitions in the US and the UK. Individual articles focusing on either the US or the UK also found that, in both countries, essential workers were impacted; those with disabilities were more often affected by Covid-19 related comorbidities in both countries. In addition, in both the US and the UK, people living in multigenerational families were more susceptible to Covid-19. Misclassification of causes of morbidity and mortality was noted in both countries. Discussion and conclusion: A limited literature indicates that, in both the US and UK, non-White populations were more affected by the Covid-19 pandemic, possibly due to association of SDOH with racist systems. Racial definitions differ between these countries and this needs further research. In both countries, data focused on LGBTQ+ groups and people with disabilities is lacking. (shrink)

Criticism can sometimes provoke defensive reactions, particularly when it implicates identities people hold dear. For instance, feminists told they are upholding rape culture might become angry or upset, since the criticism conflicts with an identity that is important to them. These kinds of defensive reactions are a primary focus of this paper. What is it to be defensive in this way, and why do some kinds of criticism, or implied criticism, tend to provoke this kind of response? What are the (...) connections between defensiveness, identity, and active ignorance? What are the social, political, and epistemic consequences of the tendency to defensiveness? Are there ways to improve the situation? (shrink)

An ad hominem fallacy is committed when an individual employs an irrelevant personal attack against an opponent instead of addressing that opponent’s argument. Many discussions of such fallacies discuss judgments of relevance about such personal attacks, and consider how we might distinguish those that are relevant from those that are not. This paper will argue that the literature on bias and testimony can helpfully contribute to that analysis. This will highlight ways in which biases, particularly unconscious biases, can make ad (...) hominem fallacies seem effective, even when the irrelevance is recognized. (shrink)

Feminist epistemologies consider ways in which gender influences knowledge. In this article, I want to consider a particular kind of feminist empiricism that has been called feminist radical empiricism. I am particularly interested in this view's treatment of values as empirical, and consequently up for revision on the basis of empirical evidence. Proponents of this view cite the fact that it allows us to talk about certain things such as racial and gender equality as objective facts: not just whether we (...) have achieved said equality in our society, but whether we are, in fact, all equal. I will raise the concern that the way in which they model the role of values in epistemology may be a problematic idealization of the open-mindedness of human agents. In some cases, resistance to value-change cannot be diagnosed as a failure to respond adequately to evidence. If so, the strategy of empirically testing our values that some feminist radical empiricists suggest may not be as useful a tool for social change as they think. (shrink)

L’article discute les conceptions respectives que le philosophe Ernst Cassirer et l’historien de l’art Erwin Panofsky se font de l’espace artistique. L’occasion en est donnée par une discussion lors du Kongress für Ästhetitk und Allgemeine Kunstwissenschaft (Congrès d’esthétique et de science de l’art) organisé à Hambourg en 1933 sur la question de l’espace et du temps artistiques. La perspective, considérée par Panofsky comme une forme symbolique, constitue un bon cas pour saisir les proximités et différences entre l’historien de l’art et (...) le philosophe des formes symboliques. L’espace de la perspective correspond-il à cet espace de l’art que le philosophe définit comme espace de la représentation (Darstellung)? À cet exemple de la perspective, exemple classique quoique souvent évoqué sans grande précision pour comparer les deux théoriciens, l’article en ajoute un autre, inédit, à savoir celui de la théorie des proportions. Peut-on dire que la théorie des proportions qui structure elle aussi la surface de l’image est, comme la perspective, une forme symbolique? La réponse permet de préciser la façon dont Cassirer et Panofsky construisent un lien entre art, représentation et subjectivité. À travers cette recherche des affinités et différences dans la conception de l’art, ce qui se joue en toile de fond, c’est, d’une part, la possibilité et les limites de l’interdisciplinarité et du dialogue fécond entre philosophie et histoire de l’art et, d’autre part, la question de savoir si une commune théorie de l’art était partagée à Hambourg dans ces années, autour de l’Institut Warburg. (shrink)

Janice Moulton's “The Adversary Method: A Philosophical Paradigm” articulated several criticisms of the popular idea of philosophy as adversarial debate. Moulton criticizes it on epistemic grounds, arguing that philosophy's overreliance on adversarial debate is to the detriment of its goals. Some, notably Trudy Govier, have argued in favor of at least a minimal adversariality, governed by norms of respectful argumentation. This paper suggests that Govier's faith in these norms is misplaced, because it neglects the social circumstances of the arguers. While (...) some authors have argued that politeness and aggression apply differently to those of different genders, this paper extends that analysis to social identities other than gender. In fact, given certain assumptions about the philosophy of language, engagement in polite adversarial debate may not even be possible for people occupying certain social locations. (shrink)

There are many good reasons to learn about the lives of people who have less social privilege than we do. We might want to understand their circumstances in order to have informed opinions on social policy, or to make our institutions more inclusive. We might also want to cultivate empathy for its own sake. Much of this knowledge is gained through social scientific or humanistic research into others' lives. The entitlement to theorize about or study the lives of marginalized others (...) is often granted under the presumption of academic freedom. This paper will not question whether academic freedom licenses us to do so in the first place ; instead, I will... (shrink)

Abstract The infantilization of older adults seems morally deplorable whereas very young children are appropriate recipients of such treatment. Children, we argue, are not mentally capable of acting autonomously and reasoning clearly. However, we have difficulty reconciling this justification with the fact that many of the elders whom we respect are mentally deficient in those very same ways. In this paper, I try to make sense of this asymmetry between our justifications for infantilizing the young and our conviction that our (...) elders ought to be respected. I argue that our intuitions against adult infantilization are non-consequentialist (i.e., deontic). I consider several candidates for the deontic factor that might explain the asymmetry of our judgments and practices. I argue that a very specific kind of dignity (one that is socially constructed and reified) grounds our disparate judgments and treatments of very young and very old persons with similar needs. (shrink)

Ethics is demanding by nature, telling us what we should or should not do. But one ethical theory in particular, utilitarianism, is more demanding than most, and is often criticized as requiring too much of us. Neither utilitarianism nor deontology requires Superman to care about truth, justice, or the American way. It might not be possible for Superman to be supererogatory since very little is above or beyond the call of duty for him, given our incredibly high expectations. Virtue ethics (...) has the best chance to explain how Superman can perform supererogatory acts, since it doesn't focus on good action as such, but rather good character. While people use the name “big blue boy scout” in a derogatory way with Superman, it is a nice way to capture an ethical theory that might grant Superman’s responsibilities while allowing him a chance to live his own life: virtue ethics. (shrink)

IntroductionRecent research investigating the benefits of being outdoors and contact with nature in children showed strong associations with children’s health and development. More teachers are choosing to integrate outdoor learning into their practice in Quebec, but few studies have focused on OL in the school environment, particularly in Canada and more specifically in Quebec, despite the fact that the school context lends itself favorably to this practice.ObjectiveThe purpose of this study was to portray OL in preschool and primary schools in (...) Québec by identifying three key elements: teachers’ perception of the outdoors, the uses of OL in schools, and teaching strategies and factors that influence teachers’ integration of OL.MethodologySemi-structured group interviews conducted with 14 teachers and participant observations were used for data collection. Inclusion criteria were to be a preschool or primary school teacher, to have taught at least eight sessions of OL in the past year, and to have no connection or contact with the research team prior to the start of the study.ResultsFirst, the results showed that teachers commonly understood the outdoors as being in the open air, practicing a physical activity, having the presence of nature, providing physical freedom and targeting a pedagogical intention. Second, teachers appeared to incorporate a variety of pedagogical intentions in OL, in a variety of settings, and with a variety of academic subjects and learning tasks. Third, teachers used a wide range of teaching strategies in OL. Participants also identified multiple factors specific to their setting that appeared to facilitate or limit their integration of OL into the school environment.ConclusionThis study provided a better understanding of the current use of the OL in the Quebec school environment by identifying the common characteristics, limitations and winning strategies of its use in schools. Teachers and schools interested in OL could benefit from the results of this study, particularly those interested in adopting a Forest School or Udeskole approach. (shrink)

The transition of novel and potentially promising medical therapies into their initial human clinical trials can engender conflicting pressures. On the one side, because Phase I trials raise greater ethical and human protection challenges than later stage clinical trials, there is a need to proceed cautiously. This is particularly the case for Phase I trials with a novel therapy being tested in humans for the first time, usually termed first-in-human (FIH) trials, especially if the FIH trial involves significant risks. On (...) the other side, scientists interested in having their research validated, corporations with a financial interest in the field, and potential patients and patient support groups desirous of having .. (shrink)

This article aims to demonstrate how the caracteristics creating the image of the dragon are used for the nomination and the definition of plants. To do so, the methodological tools of the science of the imaginary, of litterature and of linguistic are requirred. At first, the article develops the study of the latine etymology of dragon and its derivations showing the persistent links between the image of dragon and the image of some plants. Then, the article studies the french and (...) botanical names of plants evoking the imaginary of dragon such as the common dracunculus, Dracunculus vulgaris Schott, the tarragon, Artemisia dracunculus L. and the dragon tree, representing trees belonging to the genus of Dracaena Vand. ex L. (shrink)

This book is a practical guide for K-12 educators as well as parents of students who are identified as being in the top academic percentiles of the population.

In order to define modernity in the fine arts, music, and literature, this work explores the function of this category as it is used by artists, art critics, historians, and philosophers to rethink the norms of art and the links between art, politics, and life.

In 2000, the publication of ten texts marked the completion of a two-year project entitled Le Devoir de mémoire, which had brought together ten writers from across Africa to write in response to the Rwandan genocide. This article looks at how the project was posited from the outset as a specifically African response, setting this in the context of older problems of voice, selfrepresentation and the renegotiation of miswritten histories in the postcolonial context. This aspect of the project is made (...) all the more urgent by the actuality of the genocide, and the period of residence the writers spent in Rwanda in 1998. This article argues that the project succeeded in creating a space in which Africa as a whole is made part of the genocide, and vice versa, by raising complex questions of responsibility and by drawing on familiar themes in modern African writing, namely history, memory and identity; exile and dislocation. (shrink)

«Existe-t-il une argumentation juridique?», c’est la question à laquelle tente de répondre l’ouvrage de Stefan Goltzberg, intitulé explicitement L’argumentation juridique. Si l’auteur commence son ouvrage en posant directement la question, on en cherche aussitôt, par un réflexe de «juriste», la définition. Et il faut probablement lire l’intégralité de ce petit ouvrage pour voir se profiler une définition de l’argumentation juridique. Or, au cours de cette lecture Stefan Goltzberg nous montre en quoi chercher la définition, la poser, est déjà une marque (...) argumentative (p. 25) et certainement une marque de l’argumentation juridique. Or, Stefan Goltzberg n’est pas juriste de formation. Philosophe et linguiste, il est, notamment membre du Centre Perelman de philosophie du droit au sein duquel il a écrit une thèse de philosophie intitulé Théorie et histoire de la philosophie du droit, philosophie du droit de Chaïm Perelman, de Theodor Viehweg, de Roscoe Pound.Le droit est d’abord un objet d’ .. (shrink)

Surrogate endpoints are a common application of biomarkers to estimate clinical benefit in clinical trials, despite questions about reliability. This article discusses ongoing opportunities for their validation, in the context of a regulatory environment in which they are increasingly championed.

It is a commonly held view that Dedekind's construction of the real numbers is impredicative. This naturally raises the question of whether this impredicativity is justified by some kind of Platonism about sets. But when we look more closely at Dedekind's philosophical views, his ontology does not look Platonist at all. So how is his construction justified? There are two aspects of the solution: one is to look more closely at his methodological views, and in particular, the places in which (...) predicativity restrictions ought to be applied; another is to take seriously his remarks about the reals as things created by the cuts, instead of considering them to be the cuts themselves. This can lead us to make finer-grained distinctions about the extent to which impredicative definitions are problematic, since we find that Dedekind's use of impredicative definitions in analysis can be justified by his philosophical views. (shrink)