Harman and Lewis credit Kripke with having formulated a puzzle that seems to show that knowledge entails dogmatism. The puzzle is widely regarded as having been solved. In this paper we argue that this standard solution, in its various versions, addresses only a limited aspect of the puzzle and holds no promise of fully resolving it. Analyzing this failure and the proper rendering of the puzzle, it is suggested that it poses a significant challenge for the defense of epistemic closure.

The idea that knowledge can be extended by inference from what is known seems highly plausible. Yet, as shown by familiar preface paradox and lottery-type cases, the possibility of aggregating uncertainty casts doubt on its tenability. We show that these considerations go much further than previously recognized and significantly restrict the kinds of closure ordinary theories of knowledge can endorse. Meeting the challenge of uncertainty aggregation requires either the restriction of knowledge-extending inferences to single premises, or eliminating epistemic uncertainty in (...) known premises. The first strategy, while effective, retains little of the original idea—conclusions even of modus ponens inferences from known premises are not always known. We then look at the second strategy, inspecting the most elaborate and promising attempt to secure the epistemic role of basic inferences, namely Timothy Williamson’s safety theory of knowledge. We argue that while it indeed has the merit of allowing basic inferences such as modus ponens to extend knowledge, Williamson’s theory faces formidable difficulties. These difficulties, moreover, arise from the very feature responsible for its virtue- the infallibilism of knowledge. (shrink)

The history of productivity of the κ-chain condition in partial orders, topological spaces, or Boolean algebras is surveyed, and its connection to the set-theoretic notion of a weakly compact cardinal is highlighted. Then, it is proved that for every regular cardinal κ > א1, the principle □ is equivalent to the existence of a certain strong coloring c : [κ]2 → κ for which the family of fibers T is a nonspecial κ-Aronszajn tree. The theorem follows from an analysis of (...) a new characteristic function for walks on ordinals, and implies in particular that if the κ-chain condition is productive for a given regular cardinal κ > א1, then κ is weakly compact in some inner model of ZFC. This provides a partial converse to the fact that if κ is a weakly compact cardinal, then the κ-chain condition is productive. (shrink)

Timothy Williamson has famously argued that the principle should be rejected. We analyze Williamson's argument and show that its key premise is ambiguous, and that when it is properly stated this premise no longer supports the argument against. After canvassing possible objections to our argument, we reflect upon some conclusions that suggest significant epistemological ramifications pertaining to the acquisition of knowledge from prior knowledge by deduction.

According to the thesis of transparency, subjects can attend only to the representational content of perceptual experience, never to the intrinsic properties of experience that carry this representational content, i.e., to “mental paint.” So far, arguments for and against transparency were conducted from the armchair, relying mainly on introspective observations. In this paper, we argue in favor of transparency, relying on the cognitive neuroscience of attention. We present a trilemma to those who hold that attention can be directed to mental (...) paint. Such attention is either first-order sensory, higher-order cognitive, or higher-order sensory attention. We argue that the notion of first-order sensory attention to mental paint is incompatible with the neuroscience of sensory attention; that higher-order cognitive attention to mental paint is irrelevant to transparency; and that the notion of higher-order sensory attention to mental paint has an apparently incoherent prediction. Via elimination, these considerations support the thesis of transparency. (shrink)

Jewish business ethics in Israel addresses two major sources of economic immorality—unbounded desire and fear of economic uncertainty—through enforcement and spiritual education. Business is seen as a path to sanctity, when time is set apart for religious study, wealth is seen as originating from God, the vulnerable are protected against fraud and theft, charity is seen as an obligation, and mercy towards debtors is tempered by justice.

The progressive dissemination of artificial intelligence (AI) systems in work settings raises numerous questions and concerns regarding their consequences, whether positive or negative, on work activities and organizations. This paper presents an empirical study that was designed to identify and analyze these consequences in radiology. This study focuses on two AI systems: a voice recognition dictation system for radiological reports and a system for detecting fractures on X-rays images. Based on a qualitative analysis of field observations of work activities and (...) interviews with radiologists, emergency physicians, and medical secretaries, our findings help to provide a nuanced view on how AI may affect work in this sector. In contrast to the speculative discourse where AI is seen as a “positive” technology or as “threat” for workers, this study shows, on the one hand, how these kinds of AI systems help or may help these workers in their activities, and, on the other hand, how these systems raise problematic issues regarding their consequences not only for physicians but also for other workers such as medical assistants. (shrink)

According to an influential philosophical view I call “the relational properties view”, “perspectival” properties, such as the elliptical appearance of a tilted coin, are relational properties of external objects. Philosophers have assessed this view on the basis of phenomenological, epistemological or other purely philosophical considerations. My aim in this paper is to examine whether it is possible to evaluate RPV empirically. In the first, negative part of the paper I consider and reject a certain tempting way of doing so. In (...) the second, positive part of the paper I suggest a novel way of evaluating RPV empirically, relying on the influential object files framework. (shrink)

The paper argues that knowledge is not closed under logical inference. The argument proceeds from the openness of evidential support and the dependence of empirical knowledge on evidence, to the conclusion that knowledge is open. Without attempting to provide a full-fledged theory of evidence, we show that on the modest assumption that evidence cannot support both a proposition and its negation, or, alternatively, that information that reduces the probability of a proposition cannot constitute evidence for its truth, the relation of (...) evidential support is not closed under known entailment. Therefore the evidence-for relation is deductively open regardless of whether evidence is probabilistic or not. Given even a weak dependence of empirical knowledge on evidence, we argue that empirical knowledge is also open. On this basis, we also respond to the strongest argument in support of knowledge closure. Finally, we present a number of significant benefits of our position, namely, offering a unified explanation for a range of epistemological puzzles. (shrink)

It is relatively consistent with the existence of two supercompact cardinals that a special Aronszajn tree of height ${\aleph_{\omega_1+1}}$ is introduced by a cofinality-preserving forcing of size ${\aleph_3}$.

Let λ denote a singular cardinal. Zeman, improving a previous result of Shelah, proved that $\square _{\lambda}^{\ast}$ together with 2 λ = λ⁺ implies $\lozenge _{S}$ for every S ⊆ λ⁺ that reflects stationarily often. In this paper, for a set S ⊆ λ⁺, a normal subideal of the weak approachability ideal is introduced, and denoted by I[S; λ]. We say that the ideal is fat if it contains a stationary set. It is proved: 1. if I[S; λ] is fat, (...) then $\text{NS}_{\lambda ^{+}}$ ↾ S is non-saturated; 2. if I[S; λ] is fat and 2 λ = λ⁺, then $\lozenge _{S}$ holds; 3. $\square _{\lambda}^{\ast}$ implies that I[S; λ] is fat for every S ⊆ λ⁺ that reflects stationarily often; 4. it is relatively consistent with the existence of a supercompact cardinal that $\square _{\lambda}^{\ast}$ fails, while I[S; λ] is fat for every stationary S ⊆ λ⁺ that reflects stationarily often. The stronger principle $\lozenge _{\lambda ^{+}}^{\ast}$ is studied as well. (shrink)

This interview focuses on the history and current developments of cultural studies in Japan. Shunya Yoshimi is one of the leading figures in cultural studies in Japan since its introduction in the mid-1990s. He is currently engaged in the task of developing cultural studies in Asia with younger generations of scholars and to this end has helped established a new type of cultural movement, Cultural Typhoon, as well as contributing to expand Asian cultural studies networks, such as Inter Asia Cultural (...) Studies. He argues that cultural studies has been questioning the relationship between meaning and power in everyday life through a variety of concrete and practical fields. In fact, he argues, it is inevitable for cultural studies to ask questions about the politics, if we in cultural studies are to develop actual knowledge of cultural production and consumption today. Hence, it is essential to investigate the micro-politics of bodies in relation to macro-political processes. In the case of Japan, working on cultural studies within an existing discipline also means engaging in experiments, which ultimately could have the potential to undermine existing disciplines from within. (shrink)

Although Japan had its own distinctive ‘pre-history’ of cultural studies, which produced some excellent research on popular culture, which can be traced back to the 1920s, the current state of cultural studies has been criticized by conventional mainstream academics; whereas the younger generation has been attracted by cultural studies as a new academic trend. An important new development in cultural studies in Japan is Cultural Typhoon. This new movement seeks to avoid institutionalization and create an alternative academic public sphere alongside (...) broadened cultural practices, social activities and political interventions. Cultural studies in Japan can be seen as a part of a new diversity in cultural studies, which has some potentialities to move beyond the academy and open new dialogical spaces for communication and cultural intervention. (shrink)

König, Larson and Yoshinobu initiated the study of principles for guessing generalized clubs, and introduced a construction of a higher Souslin tree from the strong guessing principle.Complementary to the author’s work on the validity of diamond and non-saturation at the successor of singulars, we deal here with a successor of regulars. It is established that even the non-strong guessing principle entails non-saturation, and that, assuming the necessary cardinal arithmetic configuration, entails a diamond-type principle which suffices for the construction of a (...) higher Souslin tree.We also establish the consistency of GCH with the failure of the weakest form of generalized club guessing. This, in particular, settles a question from the original paper. (shrink)

There are few indulgences academics can crave more than to have their work considered and addressed by leading researchers in their field. We have been fortunate to have two outstanding philosophers from whose work we have learned a great deal give ours their thoughtful attention. Grappling with Stephen Yablo’s, and Juan Comesaña’s comments and criticisms has helped us gain a better understanding of our ideas as well as their shortcomings. We are extremely grateful to them for the attentiveness and seriousness (...) with which they have considered our arguments and to philosophical studies for giving us this opportunity. Given the substantive difference between the two response papers, there is not much beyond sincere gratitude that we can covey to them jointly. We will therefore address them in turn. (shrink)

In their paper from 1981, Milner and Sauer conjectured that for any poset P,≤, if , then P must contain an antichain of cardinality κ. The conjecture is consistent and known to follow from GCH-type assumptions. We prove that the conjecture has large cardinals consistency strength in the sense that its negation implies, for example, the existence of a measurable cardinal in an inner model. We also prove that the conjecture follows from Martin’s Maximum and holds for all singular λ (...) above the first strongly compact cardinal. (shrink)

Body & Society started in 1995. The journal has been continuously exploring and problematizing critical issues which have been opening up new horizons in the field of body studies. As an interdisciplinary journal, it has engaged with a wider range of innovative approaches to the body, which includes sociology, cultural studies, psychology, philosophy, anthropology, history, science and technology studies, sensory studies and media studies. To celebrate the 25th anniversary of Body & Society, managing editor Tomoko Tamari invited Professor Bryan (...) S Turner, who was one of the journal’s founders (with Mike Featherstone), to reflect on the academic and historical background of Body & Society along with his own academic trajectory over the last 40 years. (shrink)

This paper proposes and develops the feelings of goals hypothesis (FGH). It has two aims: first, to describe the evolutionary function of emotional feelings (EFs), and second, to describe the content and the format of EFs. According to FGH, the evolutionary function of EFs is to enable motoric flexibility. Specifically, EFs are a component of a psychological mechanism that permits differential motoric reactions to the same stimulus. Further, according to FGH, EF is a special type of mental representation with the (...) content of an action goal, and with a non-motoric, non-conceptual format. This paper thoroughly clarifies the assumptions underlying FGH and discusses its theoretical implications and empirical predictions. (shrink)

The Fukushima catastrophe has led to important practical and conceptual shifts in contemporary Japanese architecture which in turn has led to a re-evaluation of the influential 1960s Japanese modern architecture movement, Metabolism. The Metabolists had the ambition to create a new Japanese society through techno-utopian city planning. The new generation of Japanese architects, after the Fukushima event, no longer seek evolutionally social change; rather, the disaster has made them re-consider what architecture is and what architects can do for people who (...) had everything snatched from them by technology (nuclear power station) and nature (earthquake and tsunami). Drawing on the architectural projects of Tange Kenzo and Metabolists in the 1960s and Ito Toyo’s ‘Home-for-All project’ in 2011, the paper explores this major paradigm shift in Japanese architectural theory and practices. (shrink)

This paper provides an economic justification for the exemption from liability for omissions in torts and for the exceptions to this exemption. It interprets the differential treatment of acts and omissions under tort law as a proxy for a more fundamental distinction between harms caused by multiple injurers, where each one can single-handedly prevent the harm, and harms caused by a single injurer. Since the overall cost to which a group of injurers is exposed is constant, attributing liability to many (...) injurers reduces the part each has to pay and, consequently, reduces each one’s incentives to take precautions. Broad exemption from liability for omissions is a way of carving a simple, practical rule to distinguish between the typical cases in which an agent can be easily selected and provided with sufficient incentives and cases in which there is a serious problem of dilution of liability. The exceptions to the rule exempting from liability for omissions are explained in terms of efficiency. The imposition of liability for omissions depends on the ability to identify a salient agent, i.e., to single out one or few liable agents and differentiate their role from that of others. Tort law designs three types of "salience rules." It either creates salience directly, or it can exploit salience created "naturally," or it can induce injurers to create salience voluntarily. (shrink)

It takes courage to characterize feminist writings on tort law as "thin." Indeed, Professor Schwartz in his provocative and challenging article examines feminist writings in a unique and innovative way. In his analysis of a number of such writings, he attempts to demonstrate that they either have not done enough or could have done better. His provocative analysis of many issues invites vigorous discussion. One could write a separate comment on each and every one of the issues he raises; however, (...) I will limit my comment to two: the tension between the "reasonable man" and the "reasonable woman" standard and the duty to rescue rule. It takes courage to characterize feminist writings on tort law as "thin." Indeed, Professor Schwartz in his provocative and challenging article examines feminist writings in a unique and innovative way. In his analysis of a number of such writings, he attempts to demonstrate that they either have not done enough or could have done better. His provocative analysis of many issues invites vigorous discussion. One could write a separate comment on each and every one of the issues he raises; however, I will limit my comment to two: the tension between the "reasonable man" and the "reasonable woman" standard and the duty to rescue rule. (shrink)

A commonly-discussed feature of perceptual experience is that it has ‘assertoric’ or ‘phenomenal’ force. We will start by discussing various descriptions of the assertoricity of perceptual experience. We will then adopt a minimal characterization of assertoricity: a perceptual experience has assertoric force just in case it inclines the perceiver to believe its content. Adducing cases that show that visual experience is not always assertoric, we will argue that what renders these visual experiences non-assertoric is that they are penetrated by belief-like (...) imaginings. Lastly, we will explain why it is that when belief-like imaginings—as opposed to beliefs (and other cognitive states)—penetrate visual experience, they render visual experiences non-assertoric. (shrink)

We study the behaviour of stable types in rosy theories. The main technical result is that a non-þ-forking extension of an unstable type is unstable. We apply this to show that a rosy group with a þ-generic stable type is stable. In the context of super-rosy theories of finite rank we conclude that non-trivial stable types of U þ -rank 1 must arise from definable stable sets.

The ethical issues involved in bankruptcy affect the debtor, the creditor and the society in which they operate. Facing the debtor is his responsibility to pay back the loans and credit extended to him while the creditor has to decide whether or not to press his legal rights, irrespective of the consequences to the debtor. Society will have to determine to what extent, if any, it is prepared or obligated to fund the rehabilitation of the debtor and those employees, whose (...) employment is terminated as a result of the bankruptcy. These issues will be determined according to the value structure of the particular souly in which debtor and creditor operate. This paper views the issues in a Jewish perspective. Debtors are considered to always be liable for their debts and there is a moral shame attached to bankruptcy, except in those cases where it is caused by natural disasters. While creditors are taught and encouraged to voluntarily waive their rights, this is considered charity with all its negative overtones. The courts are obligated to review the debtors assets and sell them, if necessary, to meet the creditors loans, leaving only basic necessities for minimal living of the debtor and his family. Society however, including the creditor, a part of the group, are obligated to fund the rehabilitation of the debtor either through its interest-free loan, charity or the provision of alternative employment. These may be funded out of communal taxes. (shrink)

Perception can’t have disjunctive content. Whereas you can think that a box is blue or red, you can’t see a box as being blue or red. Based on this fact, I develop a new problem for the ambitious predictive processing theory, on which the brain is a machine for minimizing prediction error, which approximately implements Bayesian inference. I describe a simple case of updating a disjunctive belief given perceptual experience of one of the disjuncts, in which Bayesian inference and predictive (...) coding pull in opposite directions, with the former implying that one’s confidence in the belief should increase, and the latter implying that it should decrease. Thus, predictive coding fails to approximately implement Bayesian inference across the interface between belief and perception. (shrink)

According to the influential thesis of attentional transparency, in having or reflecting on an ordinary visual experience, we can attend only outwards, to qualities the experience represents, never to intrinsic qualities of the experience itself, i.e., to “mental paint.” According to the competing view, attentional semitransparency, although we usually attend outwards, to qualities the experience represents, we can also attend inwards, to mental paint. So far, philosophers have debated this topic in strictly armchair means, especially phenomenological reflection. My aim in (...) this paper is to show how to design an experiment, using the change detection paradigm for studying visual working memory that, if yielding positive results, would support AS. The structure of the argument is as follows. In standard change detection tasks, which involve attention to qualities the experience represents, there exists a known object integration effect (Luck and Vogel in Nature 390(6657):279–281, 1997). I formulate a hypothesis I call “the turn-off hypothesis,” according to which this effect does not exist in change detection tasks where subjects are instructed to attend to mental paint. I argue that, given AS, we have some reason to expect the turn-off hypothesis to be true, but given AT, we do not. Consequently, the truth of the turn-off hypothesis would support AS. I further argue that one can straightforwardly test the turn-off hypothesis, taking the standard change detection paradigm and instructing participants to attend inwards. (shrink)

Generalising Hrushovski's fusion technique we construct the free fusion of two strongly minimal theories T₁, T₂ intersecting in a totally categorical sub-theory T₀. We show that if, e.g., T₀ is the theory of infinite vector spaces over a finite field then the fusion theory Tω exists, is complete and ω-stable of rank ω. We give a detailed geometrical analysis of Tω, proving that if both T₁, T₂ are 1-based then, Tω can be collapsed into a strongly minimal theory, if some (...) additional technical conditions hold—all trivially satisfied if T₀ is the theory of infinite vector spaces over a finite field Fq. (shrink)

The success of the London 2012 Paralympic Games not only revealed new public possibilities for the disabled, but also thrust the debates on the relationship between elite Paralympians and advanced prosthetic technology into the spotlight. One of the Paralympic stars, Oscar Pistorius, in particular became celebrated as ‘the Paralympian cyborg’. Also prominent has been Aimee Mullins, a former Paralympian, who became a globally successful fashion model by seeking to establish a new bodily aesthetic utilizing non-organic body parts. This article examines (...) how the modern discourse of prostheses has shifted from the made-up and camouflaged body to the empowered and exhibited body to create a new cultural sensitivity in terms of body image – prosthetic aesthetics. Prosthetic aesthetics oscillates between two polarized sensitivities: attractiveness/‘coolness’, which derive from the image of a perfect human-machine synthetic body, and from abjection/the uncanny, which is evoked by the actual materiality of the lived body incorporating a lifeless human-made body part. (shrink)

We show that any structure of finite Morley Rank having the definable multiplicity property has a rank and multiplicity preserving interpretation in a strongly minimal set. In particular, every totally categorical theory admits such an interpretation. We also show that a slightly weaker version of the DMP is necessary for a structure of finite rank to have a strongly minimal expansion. We conclude by constructing an almost strongly minimal set which does not have the DMP in any rank preserving expansion, (...) and ask whether this structure is interpretable in a strongly minimal set. (shrink)

Recent histories of American jurisprudence tend to ignore the fact that ideas that appeared in the United States often appeared simultaneously in Europe. Even those works that do not ignore the European context are content with tracing the influence or reception of European thought in America. This article suggests that another possible approach is to compare jurisprudential developments in the United States, Europe, and other places in order to reach more general, sociology-of-knowledge-like insights into the reasons why certain ideas appear (...) at certain times and places. One concrete example is discussed: the rise of an interest in the distinction between formal and "living" law in American and European jurisprudence in the first decade of the twentieth century. This distinction was central to the work of Roscoe Pound in the United States and the work of the Austro-Hungarian legal thinker Eugen Ehrlich. Pound and Ehrlich shared similar personal backgrounds. When they began advocating the study of informal law, both Pound and Ehrlich were teaching law in provincial towns situated on the frontiers of empires. Both towns were marginal places where different cultures clashed and where the legal culture of the center of the empire had only a tenuous hold. Scholars working in such an environment, it is argued, would tend to be more aware of the gap between formal state law and the actual norms governing the daily lives of people than scholars working at the center of an empire. The article offers additional support for this argument by looking at the scholarship of Guido Tedeschi, an Italian-Israeli legal scholar who taught at the Hebrew University of Jerusalem in the 1940s. The article concludes by calling for the study of the history of American jurisprudence from a comparative perspective, taking into account such issues as the interaction between center and periphery and between empire and provinces in more than one national context. (shrink)

Tax law is a technical area of law which does not seem to be culturally specific. It is thus seen as easily transferable between different societies and cultures. However, tax law is also based on definitions and notions which are not universal. So, is tax law universal or particular? Is it indeed easily transferable between different societies? And in what ways does tax law reflect ethnic or cultural rather than economic differences? This Article seeks to answer these questions by analyzing (...) one specific example — the history of income tax legislation in Mandatory Palestine. This history reveals the dual nature of income taxation. On the one hand, the Income Tax Ordinance which was enacted by the British in Palestine in 1941 was based on a one-size-fits-all colonial model, and the lawyers involved in its enactment, in Palestine and in the Colonial Office in London, made relatively little effort to adapt it to local conditions. On the other hand, other actors — the officials, politicians and businessmen involved in the initial debate about the imposition of income taxation in Palestine in the 1930s, and the administrators involved in the application of the specific rules of the Ordinance after it was enacted in the 1940s — were aware of the need to adapt the law to the specific conditions of Palestine. Thus, while on a formal level the Ordinance seems to represent a process in which the tax law of Palestine converged with that of other British colonies, once we expand our framework and examine not just law in the books, but also law in action, and actors such as politicians and administrators, we discover that particular local conditions were an important factor in the enactment and application of the Palestine Income Tax Ordinance. The study of the process of transplantation, the Article concludes, should therefore focus not only on the formal norms being transplanted, but also on the role of the different non-legal actors involved in the process. (shrink)

The apparent inconsistency between Locke’s commitment to legalism and his explicit endorsement of the extra-legal power of prerogative has confounded many readers. Among those who don’t ignore or dismiss it, the common approach is to qualify the role or scope of prerogative. The article advocates the opposite approach. It argues that Locke’s legalism should be understood within the context of his oft neglected conception of political liberty in terms of self-government. This not only allows for the reconciliation of Locke’s legalism (...) with his endorsement of extra-legal powers, but also provides a fuller, more accurate account of the role of law and of political liberty in Locke’s theory. (shrink)

Unlike authoritarians of old, the current crop of authoritarian demagogues does not explicitly reject the democratic framework. Instead, they undermine it from within. Rather than engage their opponents on the issues, demagogues delegitimize them. As ancient Greeks had observed, turning political rivals into enemies is highly effective because it answers a need. Demagogy is driven by demand. This poses a distinct challenge to the ideals of free speech and freedom of the press, which are justified and understood in terms of (...) market competition or ‘the marketplace of ideas’. (shrink)

Let E be an analytic equivalence relation on a Polish space. We introduce a framework for studying the possible “reasonable” complete classifications and the complexity of possible classifying invariants for E, such that: (1) the standard results and intuitions regarding classifications by countable structures are preserved in this framework; (2) this framework respects Borel reducibility; and (3) this framework allows for a precise study of the possible invariants of certain equivalence relations which are not classifiable by countable structures, such as (...) E1. In this framework we show that E1 can be classified, with classifying invariants which are κ-sequences of E0-classes where κ=b, and it cannot be classified in such a manner if κshrink)

Following the Body & Society special issue, Skin Matters: Thinking Through the Body’s Surfaces (vol. 24, 1–2), Tomoko Tamari conducted an interview with the special issue editor, Marc Lafrance. He argues for the skin as an interface, which both resists and reinforces binary oppositions. Lafrance is particularly interested in the relationship between the skin and subjectivity, focusing on those who are suffering from traumatic stigmatizing experiences. This theme is also elaborated in the debates around the issue of human-made skin (...) in ‘regenerative medicine’. He argues that while the development of medical technology for human-made organic skin tends often to be welcomed, the actual experience of face-transfer patients following skin graft surgeries is one of physical and psychological hardship along with a complex sense of self-wholeness and ‘reflexive embodiment’. Reflexivity is also an important phenomenon encouraged by the media and social media, which constantly feature representations of the skin. (shrink)

Magnetic resonance imaging (MRI) is an imaging technique with a rapidly expanding application range. This methodology, which relies on quantum physics and substance magnetic properties, is now being routinely used in the clinics and medical research. With the advent of measuring functional brain activity with MRI (functional MRI), this methodology has reached a larger section of the neuroscience community (e.g. psychologists, neurobiologists). In the past, the use of MRI as a biomarker or as an assay to probe tissue pathophysiological condition (...) was limited. However, with the new applications of MRI: molecular imaging, contrast‐enhanced imaging and diffusion imaging, MRI is turning into a powerful tool for in vivo characterization of tissue pathophysiology. This review focuses on the diffusion MRI. Although it only measures the averaged Brownian translational motion of water molecules, using different analysis schemes, one can extract a wide range of quantitative indices that represent tissue morphology and compartmentalization. Statistical and visualization routines help to relate these indices to biologically relevant measures such as cell density, water content and size distribution. The aim of this review is to shed light on the potential of this methodology to be used in biological research. To that end, this review is intended for the non‐MRI specialists who wish to pursue biological research with this methodology. We will overview the current applications of diffusion MRI and its relation to cellular biology of brain tissue. BioEssays 30:1235–1245, 2008. © 2008 Wiley Periodicals, Inc. (shrink)