Suppose several individuals (e.g., experts on a panel) each assign probabilities to some events. How can these individual probability assignments be aggregated into a single collective probability assignment? This article reviews several proposed solutions to this problem. We focus on three salient proposals: linear pooling (the weighted or unweighted linear averaging of probabilities), geometric pooling (the weighted or unweighted geometric averaging of probabilities), and multiplicative pooling (where probabilities are multiplied rather than averaged). We present axiomatic characterisations of each class of (...) pooling functions (most of them classic, but one new) and argue that linear pooling can be justified procedurally, but not epistemically, while the other two pooling methods can be justified epistemically. The choice between them, in turn, depends on whether the individuals' probability assignments are based on shared information or on private information. We conclude by mentioning a number of other pooling methods. (shrink)

The predominant view is that a study using health data is observational research and should require individual consent unless it can be shown that gaining consent is impractical. But recent arguments have been made that citizens have an ethical obligation to share their health information for research purposes. In our view, this obligation is sufficient ground to expand the circumstances where secondary use research with identifiable health information is permitted without explicit subject consent. As such, for some studies the Institutional (...) Review Board/Research Ethics Committee review process should not assess the practicality of gaining consent for data use. Instead the review process should focus on assessing the public good of the research, public engagement and transparency. (shrink)

The future of health research will be characterised by three continuing trends: rising demand for health data; increasing impracticability of obtaining specific consent for secondary research; and decreasing capacity to effectively anonymise data. In this context, governments, clinicians and the research community must demonstrate that they can be responsible stewards of health data. IRBs and RECs sit at heart of this process because in many jurisdictions they have the capacity to grant consent waivers when research is judged to be of (...) particular value. However, several different terms are used to refer to this value, indicating a lack of conceptual clarity regarding the appropriate test for access to health data for research without consent. In this paper we do three things. First we describe the current confusion and instability in terminology relating to public interest in the context of consent waivers. Second we argue for harmonisation of terminology on the grounds of clarity, transparency and consistency. Third we argue that the term ‘public interest’ best reflects the normative work required to justify consent waivers because it is the broadest of the competing terms. ‘Public interest’ contains within its scope positive and negative implications of a study, as well as welfare, justice and rights considerations. In making this argument, we explain the normative basis for consent waivers, and provide a starting place for further discussion about the precise conditions in which a given study can be said to advance the public interest. Ipsos MORI study found that: … the public would be broadly happy with administrative data linking for research projects provided Those projects have social value, broadly defined. Data are de-identified. Data are kept secure. Businesses are not able to access the data for profit. (shrink)

In this article we explore the emergence of a cluster of social movement organisations that have critically taken issue with nanotechnology in Germany, the UK and internationally. By applying concepts borrowed from Social Movement Research we demonstrate that this cluster is a ‘spin-off’ from the preceding movement against agrofood biotechnology, however, never succeeds in mobilizing a comparable ‘antinanotechnology movement’. We argue that the turn toward participatory and deliberative practices that is characteristic of nanotechnology policy and, to a major extent, is (...) based on the perceived threat of a ‘public backlash’ against nanotechnology, while being of little political impact, reinforces the activity of these critical organisations through the provision of political opportunities. We further argue that the stagnation of these organisations can be explained by low policy impact and low public responsiveness respectively and conclude that their trajectories hinge to a major extent on policy impact and the responsiveness of the mass-public. We end by making a concluding remark about the limits to the project of democratizing social contention through public engagement. (shrink)

In their response to ‘Public interest in health data research: laying out the conceptual groundwork’, Grewal and Newson critique us for inattention to the law and putting forward an impracticably broad conceptual understanding of public interest. While we agree more work is needed to generate a workable framework for Institutional Review Boards/Research Ethics Committees, we would contend that this should be grounded on a broad conception of public interest. This broadness facilitates regulatory agility, and is already reflected by some current (...) frameworks such as that found in the guidelines approved under Australia’s Privacy Act. It remains unclear which elements of our broad account Grewal and Newson would reject, or indeed where the substantive disagreement with our position lies. (shrink)

First published in English in1966, _The True and The Evident_ is a translation of Franz Brentano’s posthumous _Wahrheit und Evidenz_, edited by Oscsar Kraus. The book includes Brentano’s influential lecture "On the Concept of Truth", read before the Vienna Philosophical Society, a variety of essays, drawn from the immense wealth of Brentano’s unpublished material, and letters written by him to Marty, Kraus Hillebrand, and Husserl. Brentano rejects the familiar versions of the "correspondence theory of truth" and proposes to define (...) the true in terms of the evident. In criticising the metaphysical assumptions presupposed by the correspondence theory, he sets forth a conception of language and reality that has subsequently become known as "reism". (shrink)

This paper examines the US Atomic Energy Commission’s radioisotope distribution program, established in 1946, which employed the uranium piles built for the wartime bomb project to produce specific radioisotopes for use in scientific investigation and medical therapy. As soon as the program was announced, requests from researchers began pouring into the Commission’s office. During the first year of the program alone over 1000 radioisotope shipments were sent out. The numerous requests that came from scientists outside the United States, however, sparked (...) a political debate about whether the Commission should or even could export radioisotopes. This controversy manifested the tension between the aims of the Marshall Plan and growing US national security concerns after World War II. Proponents of international circulation of radioisotopes emphasized the political and scientific value of collaborating with European scientists, especially biomedical researchers. In the end, radioisotopes were shipped from the Commission’s Oak Ridge facility to many laboratories in England and continental Europe, where they were used in biochemical research on animals, plants, and microbes. However, the issue of radioisotope export continued to draw political fire in the United States, even after the establishment of national atomic energy facilities elsewhere. (shrink)

Making data broadly accessible is essential to creating a medical information commons. Transparency about data-sharing practices can cultivate trust among prospective and existing MIC participants. We present an analysis of 34 initiatives sharing DNA-derived data based on public information. We describe data-sharing practices captured, including practices related to consent, privacy and security, data access, oversight, and participant engagement. Our results reveal that data-sharing initiatives have some distance to go in achieving transparency.

The question which this paper examines is that of the correct scope of the claim that extra-linguistic factors (such as gender and social status) can block the proper workings of natural language. The claim that this is possible has been put forward under the apt label of silencing in the context of Austinian speech act theory. The ‘silencing’ label is apt insofar as when one’s ability to exploit the inherent dynamic of language is ‘blocked’ by one’s gender or social status (...) then one might justly be said to be silenced. The notion that factors independent of any person’s linguistic competence might block her ability to exploit the inherent dynamic of language is of considerable social as well as theoretical significance. I shall defend the claim that factors independent of a person’s linguistic competence can indeed block her ability to do things with words but I will show that the cases that have been previously considered to be cases of illocutionary failure are instances of rhetic or locutionary act failure instead. I shall refine the silencing claim as previously advanced in the debate in at least one fundamental respect. I also show that considering the metaphysics of speech acts clarifies many of the issues previously appearing as thorny bones of contention between those who hold that the only notion of silencing that is coherent is that of physically preventing someone from speaking or writing and those who hold the opposite sort of claim sketched above. (shrink)

When the Toxic Substances Control Act was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of industrial chemicals, companies routinely used the agency’s obligation to protect confidential business information (...) to prevent such disclosures. This paper traces the contested history of TSCA and its provisions for testing, from the circulation of the first draft bill in the Nixon administration through the debates over its implementation, which stretched into the Reagan administration. The paucity of publicly available health and environmental data concerning chemicals, I argue, was a by-product of the law and its execution, leading to a situation of institutionalized ignorance, the underside of regulatory knowledge. (shrink)

Concerns about exploitation pervade the literature on commercial cross-border reproductive care, particularly egg selling and surrogacy. But what constitutes exploitation, and what moral weight does it have? I consider the relationship between vulnerability, limited choice, consent, and mutually advantageous exploitation. To elucidate the difference between limited choice and consent, I draw on an account of relational autonomy. In the absence of a normative principle of fair distribution, it is unclear whether the providers of reproductive goods and services are treated fairly (...) in such contracts, and therefore whether they have been exploited. I finish with some pragmatic recommendations for minimizing risks and empowering egg sellers and surrogates. (shrink)

Advances in technologies and biomedical informatics have expanded capacity to generate and share biomedical data. With a lens on genomic data, we present a typology characterizing the data-sharing landscape in biomedical research to advance understanding of the key stakeholders and existing data-sharing practices. The typology highlights the diversity of data-sharing efforts and facilitators and reveals how novel data-sharing efforts are challenging existing norms regarding the role of individuals whom the data describe.

Previous literature has documented the general issues psychologists often face while balancing their personal and professional lives. The struggle stems from attempting to satisfy the need to maintain a life outside of work while having the professional obligation to follow the American Psychological Association’s (APA’s) Ethical Principles of Psychologists and Code of Conduct (Ethics Code) to prevent their personal lives from interfering with their professional roles and relationships. The present article analyzes the subject of psychologists taking a public position on (...) controversial public issues. Although the APA Ethics Code does not restrict how psychologists conduct themselves during their personal time, taking a public stance on a controversial issue could potentially strain professional relationships and inadvertently reflect negatively on the profession. The present article examines ethical issues that (a) should be taken into account before psychologists take a public position on a controversial issue and (b) are in conflict with APA’s Ethics Code or current research. (shrink)

Philosophers who take rationality to consist in the satisfaction of rational requirements typically favour rational requirements that govern mental attitudes at a time rather than across times. One such account has been developed by Broome in Rationality through reasoning. He claims that diachronic functional properties of intentions such as settling on courses of actions and resolving conflicts are emergent properties that can be explained with reference to synchronic rational pressures. This is why he defends only a minimal diachronic requirement which (...) characterises forgetting as irrational. In this paper, I show that Broome’s diachronically minimalist account lacks the resources to explain how a rational agent may resolve incommensurable choices by an act of will. I argue that one can solve this problem by either specifying a mode of diachronic deliberation or by introducing a genuinely diachronic requirement that governs the rational stability of an intention via a diachronic counterfactual condition concerning rational reconsideration. My proposal is similar in spirit to Gauthier’s account in his seminal paper ‘Assure and threaten’. It improves on his work by being both more general and explanatorily richer in its application with regard to diachronic phenomena such as transformative choices and acts of will. (shrink)

"Aristoteles und seine Weltanschauung" ist Franz Brentanos letztes Wort in seiner lebenslänglichen Auseinandersetzung mit seinem ersten und größten philosophischen Lehrer. Indem er sich auf die aristotelische Metaphysik und hier vor allem auf die Gotteslehre konzentriert, versucht er einerseits zu zeigen, dass die oft als dunkel und widersprüchlich hingestellten Lehren des Aristoteles sich konsistent rekonstruieren lassen, und dass Aristoteles andererseits als ein Vertreter des metaphysischen Optimismus, als ein "antiker Leibniz" also, betrachtet werden kann.

Franz Rosenzweig (1886-1929) is one of the most significant German Jewish philosophers of the twentieth century. Published in German in 1920 and now finally available in English for the first time, Hegel and the State is a major contribution to the understanding of Hegel's political and social thought and a profound analysis of the intellectual currents that shaped the German state in the late nineteenth and early twentieth centuries. Through careful readings of Hegel's early handwritten manuscripts, Rosenzweig shows that (...) Hegel was wrestling with the problem of how to reconcile the subjectivity and freedom of the individual within a community and ultimately the political state. According to Rosenzweig, the route out of this conundrum chosen by Hegel shaped his mature political philosophy, where he saw the relationship between the individual and the state as reciprocal. At a deeper level, the significance of Hegel and the State lies in the way that Rosenzweig explains the failure of Hegel's quasi-communitarian view of the state to emerge, due to the authoritarian direction of the newly-unified German state under Bismarck. Anticipating the political and moral disaster that was to follow, Rosenzweig concludes by questioning the very viability of any theory of the state that relies on the pillars of bureaucratic militarism and a government-supported capitalist business culture. With the inclusion of a Foreword by Myriam Bienenstock and a substantial Afterword by Axel Honneth, Hegel and the State is a ground-breaking work of early twentieth-century philosophical and political thought. It is essential reading for students of Hegel, German Idealism, Jewish philosophy, and the origins of critical theory. It will also be of interest to those in related subjects such as the history of sociology, and German and intellectual history. (shrink)

Earp et al. (2024) sketch a thought-provoking potential use of generative AI to enhance supported decision-making for adults who have lost capacity/competence to make their own medical decisions. T...

Why Democracy Needs Public Goods provides arguments for a new theoretical perspective in favor of public goods. Kallhoff details the benefits of public goods for any democratic state: they contribute to social inclusion, help generate the public forum, and foster national identity. These arguments are supplemented by reconsidering major counter-arguments against this approach, both from political theory and from theories on public finance. Political philosophers, political theorists, and political economists will benefit most from this perspective.

Un tema recurrente en aproximaciones marxistas al estudio de la relación entre subjetividad y trabajo es la cuestión de cómo el poder capitalista configura a los individuos en la coyuntura histórica actual. En este trabajo sostenemos que la vinculación entre poder y subjetivación es históricamente contingente, mientras que el poder específicamente capitalista exige necesariamente, por sus condiciones históricas, mecanismos de subjetivación. Solo en el modo capitalista de organizar el metabolismo social es necesaria la producción generalizada de sujetos con vistas a (...) dos objetivos principales: (1) auto-generar las condiciones de existencia para su reproducción como sistema, y (2) garantizar la acumulación privada en forma de capital. Estos objetivos requieren una forma específica de poder, a saber, como dominación social a través de una lógica impersonal. Esta particularidad distingue al capitalismo de modos de producción anteriores, y se basa en la capacidad del capital para insertarse en la brecha entre la vida y sus condiciones de posibilidad. Por tanto, si podemos mostrar que los mecanismos de subjetivación dependen de las condiciones históricas del modo de producción capitalista, entonces es justo pensar que el modo de salir de este paradigma requiere la necesaria superación de dicha formación social. (shrink)