Excerpt from Le Probleme de la Verite dans la Philosophie de Spinoza Pleant, ont partage l'opinion favorable qu'en ont recue le signataire de ces lignes, rapporteur du memoire, et, peu apres lui, a son entree en fonctions a la Faculte, M. Gueroult, professeur d'histoire de la philo sophie, qui ont pris l'initiative d'en demander l'impression la Com mission des Publications. Nous le soumettons avec confiance au juge ment du public philosophique. About the Publisher Forgotten Books publishes hundreds of thousands of (...) rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

We reply to the Ioannidis's paper "Effectiveness of antidepressants; an evidence based myth constructed from a thousand controlled trials." We disagree that antidepressants have no greater efficacy than placebo. We present the efficacy from hundreds of trials in terms of the percentage of patients with a substantial clinical response (a 50% improvement or more symptomatic reduction). This meta-analysis finds that 42-70% of depressed patients improve with drug and 21%-39% improve with placebo. The response benefit of antidepressant treatment is 33%-11% greater (...) than placebo. Ioannidis argues that it would be vanishingly smaller because systematic biasing in these clinical trials would reduce the drug-placebo difference to zero. Ioannidis' argument that antidepressants have no benefit is eroded by his failures of logic because he does not present any evidence that there are a large number of studies where placebo is substantially more effective than drug. (To reduce to zero, one would also have to show that some of the unpublished studies find placebo better than drug and have substantial systematic or methodological bias). We also present the empirical evidence showing that these methodological concerns generally have the opposite effect of what Ioannidis argues, supporting our contention that the measured efficacy of antidepressants likely underestimates true efficacy.Our most important criticism is Ioannidis’ basic underlying argument about antidepressants that if the existing evidence is imperfect and methods can be criticized, then this proves that antidepressant are not efficacious. He presents no credible evidence that antidepressants have zero effect size. Valid arguments can point out difficulties with the data but do not prove that a given drug had no efficacy. Indeed better evidence might prove it was more efficacious that originally found.We find no empirical or ethical reason why psychiatrists should not try to help depressed patients with drugs and/or with psychotherapeutic/behavioral treatments given evidence of efficacy even though our treatment knowledge has limitations. The immense suffering of patients with major depression leads to ethical, moral, professional and legal obligations to treat patients with the best available tools at our disposal, while diligently and actively monitoring for adverse effects and actively revising treatment components as necessary. (shrink)

Les représentations et les usages de la musique hérités de l'ère de l'enregistrement sur support physiques (vinyl, cassette, CD) se sont radicalement transformés avec la généralisation des technologies numériques et de l'Internet. Tout sauf figés, les processus d'écoute sont à considérer dans l'histoire d'un ajustement progressif entre des dispositifs techniques et des dispositions d'écoute : le passage de la discomorphose à la numérimorphose constitue une étape essentielle de cette histoire marquée par le téléchargement illégal, le streaming, les lecteurs MP3 ou (...) les algorithmes de la recommandation. Pour autant, nous continuons à mobiliser des catégories ou des notions insuffisamment discutées - le genre musical, l'éclectisme, la légitimité, l'émotion esthétique, etc. -pour appréhender les pratiques et les goûts des auditeurs. De même, les approches employées en situation d'enquête semblent parfois inadaptées face au changement de régime ou d'échelle imposé parle numérique. Ouvrir la boîte noire des méthodes pour étudier représentations et pratiques à l'ère de la musimorphose, telle est l'ambition de cet ouvrage, où se côtoient sociologues, informaticiens, musicologues, psychologues cognitifs, spécialistes en sciences de la communication, de l'éducation et de gestion. (shrink)

RESUMENMoviéndose por caminos siempre complejos, la obra de Georges Bataille perdura como una de las más originales del pensamiento francés del siglo XX, donde su influencia ha sido inmensa. El presente artículo quiere mostrar el importante rol que jugarán en su obra las nociones de lo sagrado y de experiencia interior. Dicha experiencia, elemento central para entender su concepción de la religión, representará para Bataille la puesta en tela de juicio de todo lo conocido, pero también la íntima comunicación, ajena (...) al discurso racional, que se establece entre el mundo profano y el mundo sagrado.PALABRAS CLAVESAGRADO, EXPERIENCIA INTERIOR, COMUNICACIÓN, SACRIFICIO, MUERTE.ABSTRACTThe work of Georges Bataille, moving through complex paths, remains as one of the most original works of the twentieth-century French thought, where his influence has been immense. This article aims to show the important role that the notions of sacred and inner experience will play in his work. This experience, the central element for understanding his conception of religion, will represent to Bataille the putting into question all the known, but also the intimate communication, foreign to rational discourse, which is set between the profane and the sacred world. KEYWORDSSACRED, INNER EXPERIENCE, COMMUNICATION, SACRIFICE, DEATH. (shrink)

El estudio se propone el análisis de la última de las parábolas del evangelio de Mateo, examinando su lenguaje y elementos teológicos fundamentales; así como también su forma y composición en la obra. El trabajo se motiva por la designación que el Papa Francisco dio al texto, comprendiéndolo como recapitulación esencial del camino cristiano fundamental que debe emprender el discípulo que desea vivir las huellas del Maestro.

Laura V. Cuaya, Raúl Hernández-Pérez y Luis Concha Instituto de Neurobiología, Universidad Nacional Autónoma de México, México Cuando tu perro … Read More →.