Macphail’s (1985) null hypothesis challenged researchers to demonstrate any differences in intelligence between vertebrate species. Rather than focus on differences, we asked whether rats would show the same unexpected, counterintuitive features of skill learning observed in humans: Factors that degrade performance during acquisition often enhance performance in a subsequent retention/autonomy phase. Providing post-trial “knowledge of results” (KR) on 30%-67% of trials instead of 100% degrades accuracy, yet increases retention in a subsequent phase without KR. We tested this feature (...) by providing three groups of rats with KR on every trial (100% KR), 67% KR, or 0% KR. We also provided operant feedback in every trial for completing the left-right lever-press skill (food for correct sequences, timeout for all others). In the autonomy phase, we assessed their ability to complete the skill independently—in the absence of differential cues and KR feedback. In agreement with human performance in the autonomy phase, 67% KR yielded higher skill accuracy than providing 100% KR. Also, providing 67% KR improved skill accuracy above that observed with operant feedback alone (0% KR). Rather than degrading performance during acquisition, the 67% KR condition yielded unexpected higher accuracy than the other conditions. Accuracy increased systematically across our extended acquisition phase, which provided each rat with over 3600 trials compared to 20-30 trials for human studies. Providing limited KR promoted skill learning in rats as it does in humans, consistent with the conjecture that both species share common learning processes. Introducing difficulties to rats during training improved their autonomy. (shrink)

Background: Ethics consultants (ECs) are increasingly expected to possess core knowledge and skills. Few data address whether ECs actually possess recommended core knowledge. We aimed to measure pediatric ECs’ understanding of ethical principles, identify knowledge gaps, and explore associations between experience/training and knowledge in pediatric ethics consultations. Methods: We identified the 2 ECs most knowledgeable in pediatric ethics from each of 45 freestanding children's hospitals and an equal number of general teaching hospitals in the United States. (...) This yielded a sample of 159 eligible pediatric ECs. Pediatric ECs were sent a survey measuring ethics training, characteristics of the ethics consultation service, and EC knowledge, as assessed by a previously validated scale entitled the Test of Residents’ Ethics Knowledge for Pediatrics (TREK-P). Of 102 completed surveys received, 99 were used in the analysis. Results: Seventy-three percent of ECs had completed ≥1 formal training modality, most commonly bioethics mini-courses, master's degrees, or certificate programs (20–30% each). Respondents infrequently received salary support (32%) or had a budget (28%) to support ethics work. The median TREK-P score was 19 (interquartile range [IQR] 17–21). Forty percent of subjects scored ≥20, surpassing the threshold of adequate performance proposed in previous work. Median scores were significantly higher among ECs with formal training in ethics but did not differ significantly by other variables. In secondary analyses, high scores (≥20) were significantly more common among ECs receiving salary support (55% vs. 33%, p = 0.04) and who had formal ethics training (47% vs. 22%, p = 0.02). Items pertaining to privacy, genetic testing, and assent, were answered incorrectly by >33% of ECs. Conclusions: High scores on a validated ethics knowledge scale were more common among ECs with salary support or formal ethics training. The study highlights knowledge gaps that warrant consideration as EC becomes a professionalized endeavor. (shrink)

Previous research has repeatedly demonstrated that providing learners with self-control over their feedback schedules enhances motor skill learning. Increased information processing under self-control conditions has been shown to contribute to these benefits. However, the timing of critical information processing for self-control participants during the acquisition of continuous tasks is unknown. The present study was designed to enhance clarity related to this issue. Participants learned a continuous tracing task under self-control (SC) or yoked (YK) conditions. Groups of participants also completed a (...) secondary cognitive load task either during or after the execution of each primary task trial. Results showed enhanced learning for SC compared to YK participants who did not complete the cognitive load task. However, this benefit was eliminated for SC participants who completed the cognitive load task either during or after the primary task. These findings suggest that effective information processing both during and after continuous task execution is critical for reaping the benefits of self-controlled practice. Further interpretations and implications of these findings as well as suggestions for future research are discussed. (shrink)

Our incomplete understanding of carcinogenesis may be a significant reason why some cancer mortality rates are still increasing. This lack of understanding is likely due to a research approach that relies heavily on genetic comparison between cancerous and non‐cancerous tissues and cells, which has led to the identification of genes of cancer proliferation rather than differentiation. Recent observations showing that a tremendous degree of natural human genetic variation occurs are likely to lead to a shift in the basic paradigms of (...) cancer genetics, in that there is a need to consider both the nature of the genes involved, and the idea that not every genetic variation identified in these genes may be associated with carcinogenesis. Based on studies using LCM and micro‐genetic analyses, we propose that significant cancer initiating events may take place during the very early stages of development of cancer‐susceptible tissues and that using such techniques might greatly help us in our understanding of carcinogenesis. BioEssays 29:678–685, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Lowe claims that having knowledge of the essence of an object is a precondition for thinking about it. Lowe supports this claim with roughly the following argument: you cannot think about something unless you know what you are thinking about; and to know what it is that you are thinking about just is to know its essence. I will argue that this line of reasoning fails because of an equivocation in the expression ‘what a thing is’, which can be (...) used to indicate the essence of the thing but also, more commonly, some description of that thing which is useful in the context to identify it. I will then consider some possible variations of the argument, both in its premises and in its conclusion, and I will argue that they either fail to produce a sound argument or they weaken the conclusion too much to preserve the philosophical interest of the result. (shrink)

_'Philosophy, from the earliest times, has made greater claims, and acheived fewer results than any other branch of learning... I believe that the time has now arrived when this unsatisfactory state of affairs can be brought to an end'_ - _Bertrand Russell_ So begins _Our Knowledge of the Eternal World_, Bertrand Russell's classic attempt to show by means of examples, the nature, capacity and limitations of the logico-analytical method in philosophy.

At present, specialized knowledge of human beings, society, and culture can be subdivided into the three principal conventional modalities: the philosophical, the humanistic, and the social-scientific. Each of those modalities is identifiable by its specific foundations, which are determined by the orientation, object, methods, and results of knowledge.

Fitch's Paradox and the Paradox of the Knower both make use of the Factivity Principle. The latter also makes use of a second principle, namely the Knowledge-of-Factivity Principle. Both the principle of factivity and the knowledge thereof have been the subject of various discussions, often in conjunction with a third principle known as Closure. In this paper, we examine the well-known Surprise Examination paradox considering both the principles on which this paradox rests and some formal characterisations of the (...) surprise notion, crucial in this paradox. Standard formalizations of the Surprise Examination paradox in modal logic do not seem, at first glance, to depend on either factivity or knowledge-of-factivity, but we will argue that both factivity and knowledge-of-factivity play a key implicit role in the paradox. Namely, they are implicitly, perhaps unintentionally, used in order to simplify the definition of surprise. We analyze modal logical formalizations of three versions of the paradox concluding that the Surprise Examination paradox is the result of two flaws: the assumption of knowledge-of-factivity, and the over-simplification of the definition of "surprise" accordingly. By fixing these two flaws, the Surprise Examination paradox vanishes. (shrink)

I show that from common views about propositions as sets of possible worlds and knowledge requiring a sufficiently strong safety condition one can derive a condition stating that self-knowledge of belief is only possible if the content of that belief is fully understood. I show this by a reductio. If a subject S lacks full understanding of a proposition p, then S’s belief about believing that p cannot amount to knowledge. Even though my argument is based on (...) particular views about propositions and knowledge, I argue that the same kind of argument is also available for other knowledge conditions that rule out relevant luck and other accounts of propositions. However, for many of these other accounts of knowledge the requirement for understanding p will not be full understanding, but only sufficiently high understanding. These results tell us how self-knowledge, ruling out luck and understanding belief contents relate. (shrink)

Although most of us know that human beings cannot and should not be replaced by computers, we have great difficulties saying why this is so. This paradox is largely the result of institutionalizing several fundamental misconceptions as to the nature of both trustworthy objective and moral knowledge. Unless we transcend this paradox, we run the increasing risks of becoming very good at counting without being able to say what is worth counting and why. The degree to which this is (...) occurring is the degree to which the computer revolution is already over — and the degree to which we human beings have lost. (shrink)

To the best of my knowledge, no one in recent decades has written a book of this magnitude about the semantics of natural language. Certainly, nothing available today matches this volume in depth, precision, and coherence. The authors present classical and recent results of linguistic semantics within the framework of interpretative T-theories and defend the philosophical foundations of their approach by showing how it fits into the larger enterprise of cognitive linguistics. The book also includes an array of (...) excellent exercises and a good list of references. (shrink)

Affective knowledge of God is a kind of knowledge which follows human affectivity. This knowledge takes place on two levels: the level of the natural inclination of man towards God and the level of the religious bias of man towards God. What is the nature of affective knowledge of God? It seems there are three problems in question. First of all, as there is a natural inclination towards God in man, one will be restless unless one (...) recognizes or finds God. Secondly, one who loves God has a new deeper knowledge of the divine things through connaturality and inclination. Thirdly, as the result of one's encounter with God and of uniting with Him, man experiences certain subjective states which cannot be expressed by words. (shrink)

In response to Petitmengin and Bitbol's recent account of first-person methodologies in the study of consciousness, I provide a revised model of our introspective knowledge of our own conscious experience. This model, which I call the existential constitution model of phenomenal knowledge, avoids the problems that Petitmengin and Bitbol identify with standard observational models of introspection while also avoiding an underlying metaphorical misconception in their own proximity model, which misconstrues first-person knowledge of consciousness in terms of a (...) dichotomous epistemic relationship. The end result is a clearer understanding of the unique nature and epistemic properties of our knowledge of consciousness, as well as the epistemic status of subsequent first-person reports on conscious experience. (shrink)

Although Japanese society has become aware of some types of robots, social acceptance of robots is still not widespread. This study conducted an online questionnaire survey to investigate the relationships between experiences with and knowledge of vacuum, pet-type, and communication robots and acceptance of these robots, including the intention to use and trust. The results suggested that experiences with, knowledge of functions, and acceptance of the robots differed depending on the type of robot, and the influence of (...) these factors on acceptance of the robots also differed depending on the robot types. (shrink)

This paper discusses the reproductive health knowledge of Nigerian in-school adolescents, with special reference to pregnancy occurrence at first coitus. The data were derived from an Association for Reproductive and Family Health (ARFH) survey carried out in four secondary schools in Ibadan, Nigeria, between August and October 1995. A total of 828 students were interviewed. The results revealed that the majority of sexually active adolescents were not aware of the consequences of their actions. Religious affiliation and number of (...) wives in a male adolescents parents, were found to influence adolescents’ knowledge of pregnancy probability at first coitus. This paper confirms earlier findings that the majority of Nigerian adolescents do not know the consequences of sex. Therefore, a clear-cut plan of action is needed to inform sexually active adolescents through an effective sex education programme. (shrink)

I contend that a great deal of western philosophical thought is based upon a mistaken assumption, and that is: there is something real that we can know. I argue that, on the contrary, insofar as our experience is of a world that has meaning, this experience is not of the world "as it really is," but of the world as we perceive it through language. The very process of making the world meaningful, or learning about it, is at the same (...) time a mediation of the world. ;Because the self has, for the most part, been conceived as some kind of object, in Part One I discuss the relationship between language and our experience of objects, and our experience of objects in time. In Part Two I examine the two traditional approaches to knowledge, and attempt to show that empiricism yields no knowledge of "reality" and that metaphysics is unmeaningful. I conclude that, while we cannot know what is real, we continue to desire to do so, and so continue to make the world meaningful in various ways. ;In Part Three I claim that the self is something that we cannot know--although we try to know ourselves by telling stories about ourselves to ourselves--and that all attempts to describe the self result in the creation of models. I define 'models' as broad, compelling representations of what the self is, but which are incapable of accommodating one or another obvious feature of human experience. ;In Part Four I apply all of the above to the disciplines of psychology and literary criticism. Specifically, I criticize Stanley Fish's notion of the interpretation of texts, and analyze what is called 'dissociative identity disorder' --a disorder that makes sense only on the assumption that many selves can inhabit a single body. ;Finally, in Part Five, I admit that this entire thesis is nonsense, insofar as it is an attempt to say: "This is how things are." I conclude, however, that there are greater and lesser pieces of nonsense in the world, and that the value of philosophy resides in being able to expose great nonsense as nonsense. (shrink)

As I walk into a restaurant to meet up with a friend, I look around and see all sorts of things in my immediate environment—tables, chairs, people, colors, shapes, etc. As a result, I know of these things. But what is the nature of this knowledge? Nowadays, the standard practice among philosophers is to treat all knowledge, aside maybe from “know-how”, as propositional. But in this paper I will argue that this is a mistake. I’ll argue that some (...) knowledge is constituted, not by beliefs toward propositions, but by awareness of properties and objects. Seeing isn’t believing, but it is knowing. After further characterizing this type of knowledge, I will make the case for it. Then I will consider a variety of objections. Finally, I will indicate how our recognition of this knowledge may answer other questions, and solve other problems, in philosophy. (shrink)

Objective: To assess the knowledge of four groups of individuals regarding who is legally authorised to consent to health care or research involving older patients.Design: A provincewide postal survey.Setting: Province of Quebec, Canada.Participants: Three hundred older adults, 434 informal caregivers of cognitively impaired individuals, 98 researchers in aging and 136 members of research ethics boards .Measurements: Knowledge was assessed through a pretested postal questionnaire comprising five vignettes that describe hypothetical situations involving an older adult who requires medical care (...) or is solicited for research. The respondent had to identify the person who is legally authorised to provide consent.Results: Nearly 80% of all respondents provided the correct answer when the hypothetical scenario depicted a person who was competent to consent or incompetent but legally represented. Knowledge was worse for the scenario describing a research situation that involved an incompetent adult without a legal guardian.Conclusion: The observed lack of knowledge raises doubts about the ability of current legislation to truly protect the rights of older adults with diminished decision making capacity. It points to the need for educational programmes aimed at increasing public awareness of the legislation put in place for those requiring special protection. (shrink)

Differences in difficulty between isomorphs of the Tower of Hanoi are generally explained in terms of differences in processing loads required by the different versions Kotovsky & Fallside, 1989 . Our claim is that the general knowledge about an action, activated by the context, is what guides the elaboration of problem representation. To test this hypothesis, we manipulated the context using four isomorphs. The results support the hypothesis: the selection of the adequate point of view on the action (...) depends on the context, and is a crucial step in the elaboration of problem representation. The more difficult versions are those that require abandoning the first point of view and selecting a new one. (shrink)

Recent results from neuroimaging appear to indicate that some patients in a vegetative state have partially intact awareness. These results may demonstrate misdiagnosis and suggest the need not only for alternative forms of treatment, but also for the reconsideration of end-of-life decisions in cases of disorders of consciousness. This article addresses the second consequence. First, I will discuss which aspects of consciousness may be involved in neuroimaging findings. I will then consider various factors relevant to ethical end-of-life decision-making, (...) and analyse whether and to what extent the above consequence applies to these factors. It will be shown that knowledge of the existence of partial awareness in patients with disorders of consciousness only influences end-of-life decision-making if certain background assumptions are made. (shrink)

Some of the duties of individuals and organisations involve responsiveness to need. This requires knowledge of need, so the epistemology of need is relevant to practice. The prevailing contention among philosophers who have broached the topic is that one can know one’s own needs (as one can know some kinds of desires) by feeling them. The article argues against this view. The main positive claims made in the article are as follows. Knowledge of need, in both first‐person and (...) second‐person cases, is a type of knowledge‐that with no basic epistemological source. Needs, like medical conditions, have signs and symptoms. Knowledge of these, with inference, results in knowledge of need. Finally, it is argued that need is akin to, but not a special case of, metaphysical necessity de re. Some implications of this for the epistemology of need are explained. (shrink)

In the following paper, the author will try to test the meaning of the transcendental approach in respect of the inner changes implied by the idea of quantum gravity. He will firstly describe the basic methodological Kant’s aim, viz. the grounding of a meta-science of physics as the a priori corpus of physical knowledge. After that, he will take into account the problematic physical and philosophical relationship between the theory of relativity and the quantum mechanics; in showing how the (...) elementary ontological and epistemological assumptions of experience result to be changed within them, he will also show the further modifications occurred in the development of the loop quantum gravity. He will particularly focus on the tough problem of the relationship space-matter, in order to settle the decisive question about the possibility of keeping a transcendental approach in the light of quantum gravity. He will positively answer by recalling Cassirer’s theory of the invariants of experience, although he will also add some problematic issues arising from the new physical context. (shrink)

In The Varieties of Religious Experience, William James suggests that the human experience of a fundamental and existential uneasiness can be found at the core of most religious traditions, and that these traditions constiute essentially a proposed solution to this uneasiness. The present investigation focuses upon the notion of uneasiness, particularly fear, and its solution in the early Hindu tradition. Through a close examination of textual expressions of both desire and fear from the R̥gveda, the Śatapatha Brāhmaṇa, and the Br̥hadāraṇyaka (...) Upaniṣad, it is proposed that “liberation” in the early Upaniṣadic period, or at least the precursor to the traditional notion of liberation, actually meant freedom from fear, rather than freedom from karma or saṁs̥ra. The Br̥hadāraṇyaka Upaniṣad suggests that the origin of duality is desire, and duality necessarily results in fear. By relinquishing the sorts of desires so frequently expressed in the earlier vedic literature, together with an understanding of the essentially non-dual relationship between the ātman and brahman, a state of complete freedom from fear (abhaya) may be achieved. (shrink)

Objective: To audit doctors’ knowledge of informed consent.Design: 10 consent scenarios with “true”, “false”, or “don’t know” answers were completed by doctors who care for children at a large district general hospital. These questions tested clinicians’ knowledge of who could give consent in different clinical situations.Setting: Royal United Hospital, Bath, UK.Results: 51 doctors participated . Paediatricians scored higher than other clinicians . Only 36% of paediatricians and 8% of other clinicians realised that the biological father of a (...) child born before 1 December 2003 needed a court order or a parental responsibility agreement to acquire parental responsibility, and thus be able to consent on behalf of his child, if he was not married to the child’s mother. Non-paediatric clinicians were unsure or incorrect when tested on situations where people with parental responsibility do not agree, or where young people , who are Fraser competent do not want to consult their parents. Most clinicians did not know that the parents of a 20-year-old man with severe learning difficulties are unable to consent to surgery on his behalf, and many non-paediatricians were unclear on who could give consent when a child lived with foster parents.Conclusion: Clinicians who obtain consent for the treatment of children need to increase their knowledge on who is able to give informed consent to ensure best practice. (shrink)