Berichte zur Wissenschaftsgeschichte, Volume 45, Issue 3, Page 468-486, September 2022.

: With the advent of the Genetic Age comes a unique new set of problems and ethical decisions. There is a tendency to take the scientific developments presented by modern genetics at face value, as if the science itself were value-neutral and not influenced by cultural and religious images. One example of the fallout of the Genetic Age is the development of a "genetic self," the idea that our essential selfhood lies in our genes. It is (...) important to understand the assumptions of the Genetic Age, the development of genetic selfhood, and the broader cultural trends and assumptions that underlie modern genetic thinking. It is equally important, however, to shape a reaction to the concept of a genetic self. Judaism has long carried on a unique discussion about the nature of selfhood in different times and places and about the relation of the corporeal self to the essential self. Insights from Judaism therefore may help to craft a reaction to the modern genetic self that incorporates the best of modern genetics as well as the integrity of a more transcendent selfhood. (shrink)

Contemporary understanding of human subjectivity has come a long way since the Cartesian 'thinking thing' or Freud's view of the self struggling with its unconscious. We no longer think of ourselves as stable and indivisible units or combinations thereof - instead, we see the self as constantly reinvented and reorganised in interaction with others and with its social and cultural environments. But the world in which we live today is one of uncertainty where nothing can be taken for granted. Coping (...) with change is a challenge but it also presents new opportunities. Uncertainty can be both liberating and oppressive. How does an individual understand her or his position in the world? Are we as human beings determined by our genetic heritage, social circumstances and cultural preferences, or are we free in our choices? How does selfhood emerge? Does it follow the same pattern of development in all people, all cultures, all ages? Or is it a socio-cultural construction that cannot be understood outside its historical context? Are the patterns of selfhood fundamentally changing in the present world? Does new technology allow us more autonomy or does it tempt us to give up the freedoms we have? (shrink)

Mental phenomena and consciousness can be located in sign and in language. Since these latter belong to the objective world of human interaction, consciousness emerges as a part of objectivity. A sign is the product of the interaction between consciousnesses. Thus, admitting the existence of the sign presumes the existence of action. Activity is a social phenomenon; thus, it is objective. It is the objectivization of human needs and desires as production and reproduction of these needs in society. Human consciousness (...) emerges as co-knowing or co-consciousness through linguistic activity. Consciousness as co-knowing emphasizes the genesis of human subjectivity not as a mere assertion but as something the existence of which is to be shown. Consciousness and selfhood, thus, appear as objective, mediating but subjective action. In this view, the self is emancipated consciousness. Therefore, the psyche emerges as the subjective image of objectivity. (shrink)

The far reaching effects of the genetic revolution on our lives as a whole make it difficult to separate the secular and sacred issues involvedIn accepting this opportunity to comment on Dr Polkinghorne’s Templeton Prize lecture, I recognise that there is a significant division between those who would see religious beliefs as irrelevant in the ethical debates concerning new biotechnologies and those who, with Dr Polkinghorne, are willing to look to the major faith traditions for insight into the nature (...) of human identity and selfhood. In secular discourse, the intrusion of religious language has long been resisted on many grounds: that sound ethical principles do not need transcendent ratification; that those who presume a privileged moral discernment derived from their religion frequently fail to appreciate the complexity of genetic and medical science; and that internecine disputes within faith communities and historically rooted incommensurabilities between them seriously compromise any prospect of consensus. This problem is tacitly acknowledged by Dr Polkinghorne himself when he notes that his willingness to accept the 14 day threshold before which certain forms of experimentation on embryos are deemed permissible would not be congenial to Roman Catholic officialdom, for whom the destruction of one life cannot be condoned even if it were to make possible the creation of another.Dialogue traversing a secular/sacred divide can be thwarted for other reasons. Those sympathetic to religious voices may concede that claims for privileged discernment are unhelpful but still insist that secular ethicists too readily fail to appreciate that religious beliefs can be constructive in strengthening motivation and in deepening commitment on ethical issues. Theologians who have served on ethics committees have sometimes expressed a sense of frustration accompanying their attempts to explain that they are starting from a different point, and working from different presuppositions, than those who …. (shrink)

What is your authentic self—is it something that you design and create, or something to be discovered within yourself? The philosophical literature remains somewhat divided on this question, and this lack of consensus is also reflected in the popular sphere; in fact, ordinary appeals to the notion of an ‘authentic self’ often involve diverse, if not contradictory, views on selfhood. Interestingly, the self-help psychology of Canadian author and professor Jordan Peterson offers a particularly fitting example of this conflict. The (...) argument that Peterson makes for the importance of personal authenticity in his 2018 book, 12 Rules for Life: An Antidote to Chaos, highlights some of the metaphysical and moral challenges surrounding the concept. In particular, his portrayal of the authentic self demonstrates the degree to which conflicting views of selfhood can coincide: at the same time as his belief in biological essentialism supports a view of the self as genetically fixed, his appeal to social autonomy characterises the self as free and self-determined. Nonetheless, conceiving of the self as constrained in some aspects yet autonomous in others is not an inherently contradictory position. This chapter considers the extent to which these two visions of the self can be reconciled in Peterson’s work and, firmly situated as Peterson is within contemporary discourse, what his ideas on authenticity can tell us about the wider cultural debate. (shrink)

The parsimonious consideration of research into food sharing among chimpanzees suggests that the type of social regulation found among our closest genetic relatives can best be understood as a form of morality. Morality is here defined from a naturalistic perspective as a system in which self-aware individuals interact through socially prescribed, psychologically realistic rules of conduct which provide these individuals with an awareness of how one ought to behave. The empirical markers of morality within chimpanzee communities and the traditional (...) moral traits to which they correspond are (1) self-awareness/agency; (2) calculated reciprocity/obligation; (3) moralistic aggression/blame; and (4) consolation/empathy. (shrink)

The study of literary works devoted to running makes it possible to determine their plot dominant as a conflict between the feeling of freedom generated by running and such properties of professional sports as fierce competition of competitive activities and authoritarian regulation of the training process. Sociocultural tensions of this kind were fruitfully conceptualized in the works of Michel Foucault using the concepts of bio-power as a unity of anatomical and biopolitics; disciplinary practices as methods of normalization of bodies; supervision (...) and panopticism as means of control, as well as technologies of self and subjectivation aimed at dampening the effects of excessive domination. The article uses the fantastic sports novel by Danish writer Knud Lundberg "Olympic Hope: The Story that Happened at the 1996 Olympic Games" published in 1955 and not translated into Russian as an object of application of the Fucoldian means of analyzing the above conflict situation. The research methodology is based on a conceptual analysis of M. Foucault's theoretical legacy and the reception of the French philosopher's ideas by Russian and Western scientists. The study revealed that the novel presents four variants of bio-power: German (genetic eugenics), American (hormonal eugenics), Soviet (crippling practices) and Danish (based on the free development of natural predisposition), used to organize the birth and training of top-level runners. The disciplinary practices of runner training are most pronounced in totalitarian states. The methods of their implementation are specialized closed training spaces; strict daily routine; daily monotonous running exercises; constant differentiation of athletes by rating; exams in the form of competitions; medical experiments. The realization of the technologies of selfhood and subjectivation by runners is carried out in the forms of resistance and transgression. K. Lundberg associates his Olympic hopes in sports running not with cruel professionals who are ready to give up their health (the problem of doping) and even their lives for the sake of personal awards and increasing the prestige of their states, but with educated means of humanistic sports by amateur athletes, for whom running has existential significance as a way of holistic, bodily and spiritual self-realization in the ethically loaded sphere of freedom. (shrink)

Recent work in the philosophy of biology argues that we must rethink the biological individual beyond the boundary of the species, given that a key part of our essential functioning is carried out by the bacteria in our intestines in a way that challenges any strictly genetic account of what is involved for the biological human. The gut is a kind of ambiguous other within our understanding of ourselves, particularly when we also consider the status of gastro-intestinal disorders. Hegel (...) offers us theoretical tools to describe and understand our relationship to our gut. His description of our selves as continually mediated through otherness is strikingly compatible with the kind of structure contemporary biology presents us with. His accounts of digestion and habit, contextualized by his logic, help point toward an understanding of selfhood as porous and yet still capable of being sufficiently unified for us to make sense of ourselves, one which allows us to acknowledge otherness within us while still having enough unity for agency. (shrink)

Science fiction is often used as a tool with which to think about actual science. While often this is depicted in terms of imaginary future potential, science fiction has also shown itself to be a poignant critique of existing science and a means of exploring our collective anxieties regarding the continued logic of current scientific development. This article explores the science fiction of organ transplantation, as mapped against scientific and medicolegal developments in actual organ transplantation. Explored through the lens of (...) Adorno’s work on cultural criticism, it is argued that science fiction serves as a tool with which we address (and critique) the ethical boundaries (and fears, often colonial in nature) of actual organ transplantation. Science fiction works such as Larry Niven’s Known Space Universe and Repo! The Genetic Opera are examined, demonstrating that in critiquing the science of organ transplantation, fictionists ultimately come to examine changing cultural understandings of selfhood and embodiment. (shrink)

Husserl, in his late manuscripts, made a number of apparently opposing assertions regarding the subject. These assertions are reconciled once we realize that they apply to the different stages of the genesis of the subject. This means that the subject has to be understood as a process – i.e., as continually proceeding from the living present, which forms its core, to the developed self that each of us is. As such, the subject cannot be identified with any of the particular (...) stages of its genesis. The genetic account of its becoming must be understood accordingly. It is not an account that details the progressive acquisition of features that remain as “sedimented layers” of our selfhood. Rather, such layers, like the selfhood they form, exist as part of the ongoing process, the motion, that is our subjectivity. This view, I argue, is Husserl’s final, if undeveloped, insight into the nature of our selfhood. (shrink)

Over the years, phenomenology has provided illuminating descriptions of discrimination, with its mechanisms and effects being thematised at the most basic levels of embodiment, (dis)orientation, selfhood, and belonging. What remains somewhat understudied is the lived experience of the discriminator. In this paper I draw on Husserl's phenomenological account of normality to reflect on the ways in which we discriminate at the prereflective levels of perceptual experience and bodily being. By critically reflecting on the intentional structures undergirding discriminatory practices, I (...) argue that discrimination is characteristic of a naïve normalising attitude which is habitually interested in securing a familiar experience of a static normality. I first demonstrate how this attitude problematically tends to reproduce, enforce, and further sediment discriminatory and exclusionary norms. Further, I provide an internal critique which problematises discrimination—without recourse to external normative standards—on three fronts: as epistemically unproductive, experientially obscuring, and normatively non-instantiating. In discriminatory acts we see an abnormal refusal to enrich, revise, and genetically establish new normative commitments, new ways of seeing, and a new normality. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Fichte’s Transcendental Philosophy: The Original Duplicity of Intelligence and Will by Günter ZöllerDaniel BreazealeGünter Zöller. Fichte’s Transcendental Philosophy: The Original Duplicity of Intelligence and Will. Cambridge: Cambridge University Press, 1998. Pp. xvii + 169. Cloth, $49.95.The subtitle says it all: “Original Duplicity,” which is to say, interdependent duality, or perhaps “equiprimordiality.” The thesis defended by Günter Zöller in this meticulously documented and elegantly written new book is that (...) the traditional emphasis upon the “primacy of the practical” in Fichte’s thought is seriously misleading and obscures one of the most striking aspects of his highly original transcendental analysis of consciousness and experience.Limiting his exegesis to the period of the “early” or “Jena” Wissenschaftslehre, Zöller carefully explains how “practical” and “theoretical” elements are inextricably linked at every stage of Fichte’s analysis. While it is certainly true that Fichte made a brilliant effort to demonstrate the dependence of “thinking” upon “willing,” of “knowing” upon “doing,” and hence of “theory” upon “practice,” it is no less true that, in doing so, he also established that there can be no “willing” without some prior awareness, and hence some “knowledge,” both of one’s present condition (“what is”) and of some particular goal to be accomplished by free activity (“what ought to be”). The Kantian distinction between “theoretical” and “practical” reason is, therefore, on Fichte’s analysis, simply a reflection of a more fundamental distinction between the “theoretical” and “practical” activities or powers of the I, neither of which can function in the absence of the other. [End Page 374]What Fichte proposes is, in Zöller’s phrase, a truly “integrated theory of reason,” one that begins by positing a pure and original unity of intellect and will in the mere concept of selfhood, that proceeds to a discursive, transcendental analysis of the dynamic and dialectical interplay between “theoretical” and “practical” moments in the constitution of experience (or of empirical self-consciousness), and that concludes by positing, albeit only as a regulative ideal, or as a necessary but unobtainable goal of infinite striving, the final, empirically achieved unity of theory and practice: an ideal of a self that is no longer divided against itself or others and of a world that has been wholly transformed by intellectually guided human activity. As Fichte’s account proceeds, it becomes increasingly clear not only that we must distinguish the will from the intellect—even as we continue to insist upon their systematic interdependence—but that we must also modify our original understanding of both. This conclusion is most unambiguously presented in those works of 1796–99 that collectively constitute the “second” or “revised” version of the Jena Wissenschaftslehre, including the lectures on Foundations of Transcendental Philosophy (Wissenschaftslehre) nova methodo and the System of Ethics, and it is upon an analysis of these texts that Zöller’s interpretation is chiefly based. According to the latter, an adequate theory of willing must not merely contrast and relate “the will” to “the intellect,” but must recognize that even pure volition contains a certain cognitive core and presupposes some guiding law that is simply integral to the will itself. Similarly, “mere cognition” will always be found to contain within itself, in the form of “feeling,” a certain “practical” dimension of its own.Zöller’s careful account of Fichte’s genetic deduction of the necessary interplay between theoretical and practical elements in the constitution of selfhood and experience is by far the most detailed and accurate one available in English, and forms the core of his book. It is by no means, however, the only topic he discusses. The first two chapters, for example, constitute an excellent general introduction to Fichte’s entire Jena project and include a fine discussion of the relationship between Kantian and Fichtean idealism. Chapter 3, which explicates the key notions of “positing” and “determining,” will be of immense help to anyone trying to understand German idealism in general and Fichte’s philosophy in particular. Like Kant’s ethical theory, Fichte’s is often treated in isolation from his larger system, but Zöller’s Chapter 4 clearly explicates the... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Scars of the Spirit: The Struggle Against InauthenticityChristopher S. SchreinerScars of the Spirit: The Struggle Against Inauthenticity, by Geoffrey Hartman; xii & 260 pp. New York: Palgrave Macmillan, 2002. $17.95 paper.Geoffrey Hartman is now an emeritus faculty member at Yale. All but the youngest readers of this journal will recognize him as a member of the now defunct Yale School of Criticism, which in its glory days included (...) Harold Bloom, Hillis Miller, Paul de Man, and Jacques Derrida. Among these accomplished individuals, Hartman distinguished himself as the one most engaged with discussing the role of style in theoretically propelled criticism, and this remains his lasting contribution. The question he kept asking was the following: what demands do the books we read and the theories we use make on our own critical practice, and in particular, on our style? Works such as Criticism in the Wilderness (1980) and Saving the Text (1981) were concerned with promoting a philosophical criticism that is as creative as the literature it seeks to criticize, in opposition to the Arnoldian standard of a disinterested criticism that respects and preserves the canonical hauteur of literary classics and doesn't seek to imitate them. Yet over the decades Hartman's own prose, except when it lapsed into copying Derrida's, seemed more that of the Doctor and less the Explorer, to borrow the terms Lionel Trilling used to describe Matthew Arnold's criticism. This is an irony we are grateful for.Hartman's most recent book, Scars of the Spirit, takes up the problem of authenticity in the context of postmodern culture, seeking to reestablish its legitimacy as a serious topic and unmask what merely poses as authentic in the global marketplace. Today his agenda ignominiously crosses paths with the likes of Jane Fonda, whose autobiography is replete with New Age claims to recover "the authentic me." One of the issues never resolved by Hartman's book and which taunts his project behind its back is whether his Continental erudition makes his project any more authentic than Fonda's celebrity psychobabble. Authenticity was the Heideggerian concept that Adorno ruthlessly and ironically attacked in his The Jargon of Authenticity, and it has an old-fashioned existential ring to it to this day. For those readers who haven't read Being and Time lately, authenticity (Jemeinigkeit) was the resolute impetus of making time one's own, taking it back from the instrumental public world that had appropriated it so that one can live a sincerely mortal life and die one's own death, as it were properly. Professors valiantly conjured an ethic out of this retrieval of selfhood, of one's personal property of time and destiny in the Lost and Found of culture, not fully cognizant of its Nietzschean roots. The absence of altruism in this existential ethic inspired Emmanel Levinas's patient attempt to persuade us to demote our egoism in an insatiable responsibility to and for others, for whom we can never do enough.There is surely irony in the fact that the anachrony of authenticity as a concept was accelerated by the deconstructive theory that Hartman helped [End Page 501] promulgate. Hence his new book reads a bit like someone having to gingerly retrace his steps in a field of landmines planted by the Yale School of Criticism. The question of propriety, what is right and proper, what is one's own, stamped with one's unique or authentic properties, was deconstructed by Derrida, and Hartman reverently recorded the results in the incongruously titled Saving the Text, an analysis of Derrida's attempt to promote textual intercourse between Hegel and Jean Genet by setting them in parallel columns on one page. In a nutshell, the original source of an event or text, its material advent, is untraceable due to its derivativeness, the forces of semiosis (or textuality) at play in and between texts. In parallel to this discovery, Jean Baudrillard spoke of the simulacrum as a media-generated version behind which the original "thing itself" was forever irrecoverable. The very idea of authenticity came to sound illusory, denoting a mirage sought in a hopeless regressive inquiry or Ruckfrage which Husserl (with... (shrink)

This text examines the many transformations in Husserl’s phenomenology that his discoveries of the nature of appearing lead to. It offers a comprehensive look at the Logical Investigations’ delimitation of the phenomenological field, and continues with Husserl’s account of our consciousness of time. This volume examines Husserl’s turn to transcendental idealism and the problems this raises for our recognition of other subjects. It details Husserl’s account of embodiment and takes largely from his manuscripts, both published and unpublished, dealing with his (...) theory of instincts, his considerations of mortality and the teleological character of our existence. This book appeals to students and researchers and presents a genetic account of our selfhood, one that unifies Husserl’s different claims about who and what we are. (shrink)

The rapidly changing field of genetics affects society through advances in health-care and through implications of genetic research. This study addresses the impacts of new genetic discoveries and technologies on different segments of today's society. The book begins with a chapter on genetic complexity, and subsequent chapters discuss moral and ethical questions arising from today's genetics from the perspectives of health care professionals, the media, the general public, special interest groups and commercial interests.

Signs and States, programme financé par l'ERG (European Research Council), a pour but d'explorer la sémiologie de l'Etat du XIIIe siècle au milieu du XVIIe siècle. Textes, performances, images, liturgies, sons et musiques, architectures, structures spatiales, tout ce qui contribue à la communication des sociétés politiques, tout ce qu'exprime l'idéel des individus et leur imaginaire, est ici passé au crible dans trois séries de rencontres dont les actes ont été rassemblés dans une collection, Le pouvoir symbolique en Occident (1300-1640). Ces (...) volumes, adoptant une perspective pluridisciplinaire et comparative dans une visée de long terme, combinent études de cas, analyses conceptuelles et réflexions plus théoriques. Et les réponses à ce questionnaire, issu d'une réflexion sur une histoire culturelle poursuivie sur plus de cinq siècles, remettent en cause une histoire de l'Occident latin où l'on opposerait Eglise et Etat : la mutation culturelle engendrée par la réforme grégorienne qui, tout en assurant d'abord le triomphe de la papauté, a donné à l'Etat moderne les moyens d'assurer sa propre légitimité en créant les conditions d'une révolution du système de communication. Elle engendre un partage du pouvoir symbolique et des processus de légitimation avec l'Etat : la capacité de ce dernier à se légitimer par le consentement de la société politique en dehors de la contingence religieuse est une spécificité de l'Occident latin, clé de l'essor des Etats modernes européens. (shrink)

Society has historically not taken a benign view of genetic disease. The laws permitting sterilization of the mentally re tarded~ and those proscribing consanguineous marriages are but two examples. Indeed as far back as the 5th-10th centuries, B.C.E., consanguineous unions were outlawed (Leviticus XVIII, 6). Case law has traditionally tended toward the conservative. It is reactive rather than directive, exerting its influence only after an individual or group has sustained injury and brought suit. In contrast, state legislatures have not (...) been inhibited in enacting statutes. Many of their products can be characterized as hasty, unnecessary, ill-conceived, and based on the heart rather than the head. Moreover the lack of expert consultation sought has also been remarkable. One state legislature, for example, has advocated immunization for sickle cell anemia! Many others have enacted laws for the screening of inborn errors of metabolism, e.g., phenylketon uria, but have poorly defined the lines of responsibility to secure compliance. A spate of specific disease-related bills has emerged in the u.S. Congress, each seeking recognition and appropriations. Sickle cell anemia, hemophilia, Cooley's anemia and Tay-Sachs disease have been among the front-runners for support. Finally, in 1975, Congress has begun to examine an omnibus bill concerning all forms of genetic disease. The bill, termed the National Genetic Diseases Act is, however, still far from being enacted. (shrink)

The role of fixed charges present at the surface of biological membranes is usually described by the Gouy-Chapman-Grahame theory of the electric double-layer where the Grahame equation is applied independently on each side of the membrane and where the capacitive charges are disregarded. In this article, we generalize the Gouy-Chapman-Grahame theory by taking into account both intrinsic charges and capacitive charges, in the density value of the membrane surface charges. In the first part, we show that capacitive charges couple electrostatic (...) potentials present on both sides of the membrane. The intensity of this coupling depends both on the value of the membrane specific capacitance and the transmembrane electric potential difference. In the second part, we suggest some physiological implications of membrane electric double-layers. (shrink)

The Epic of Evolution is a course taught at Northern Arizona University. It engages the task of formulating a new epic myth that is based on the physical, natural, social, and cultural sciences. It aims to serve the need of providing meaning for human living in the vast and complex universe that the sciences now depict for us. It is an interdisciplinary effort in an academic setting that is often divided by specializations; it focuses on values in a climate of (...) relativism; and it concentrates on an enterprise for which there are few textbooks at hand. The course is presented in three segments: the cosmos before humans appeared, the human phenomenon, and scenarios for the future of evolution. (shrink)

Building on the emerging literature on the ethics of social enterprises (SEs), this paper advances the underexplored role of frontline workers (FLWs) as embedded agents at the interface between communities and SEs. Specifically, we uncover the subjectivity of FLWs as they navigate moral ambiguities while performing their professional roles, dealing with rules and regulations within the organizational hierarchy and living as members of local communities. Based on an inductive case study of a microfinance organization in Cameroon, we find that FLWs (...) engage in three rationalization strategies: cautious disengaging, safeguarding self-interest, and justifying relevance. Our findings offer a better understanding of the ethics of SEs by unpacking the subjectivity of FLWs. We highlight a bottom-up account of caring SEs, identify a boundary condition to subjectivity, and present a nuanced view of FLWs in embedded organizations. We also discuss the practical implications for SEs to improve their compassion and cater for the mental wellbeing of FLWs. (shrink)

A point made repeatedly over the last few years is that the Locked-in Syndrome offers unique real-life material for revisiting and challenging certain ingrained philosophical assumptions about the nature of personhood and personal identity. Indeed, the claim has been made that a closer study of LIS will call into question some of the traditional conceptions of personhood that primarily highlight the significance of consciousness, self-consciousness and autonomy and suggest the need for a more interpersonal account of the person. I am (...) skeptical about these claims and will in the following argue that the theoretical relevance of LIS for an understanding of selfhood and personhood has been exaggerated. (shrink)

Prenatal genetic testing is becoming available for an increasingly broad set of diseases, and it is only a matter of time before parents can choose to test for hundreds, if not thousands, of genetic conditions in their fetuses. Should access to certain kinds of fetal genetic information be limited, and if so, on what basis? We evaluate a range of considerations including reproductive autonomy, parental rights, disability rights, and the rights and interests of the fetus as a (...) potential future child. We conclude that parents should be able to access information that could be useful during pregnancy, but that testing for non-medical information should be limited. Next, we argue that the government lacks a compelling state interest in regulating prenatal genetic testing and propose that regulation should occur through medical professional organizations. Finally, we present a framework for determining what testing physicians should recommend, offer neutrally, or not offer at all. (shrink)

The idea that a world in which everyone was born “perfect” would be a world in which something valuable was missing often comes up in debates about the ethics of technologies of prenatal testing and preimplantation genetic diagnosis . This thought plays an important role in the “disability critique” of prenatal testing. However, the idea that human genetic variation is an important good with significant benefits for society at large is also embraced by a wide range of figures (...) writing in the bioethics literature, including some who are notoriously hostile to the idea that we should not select against disability. By developing a number of thought experiments wherein we are to contemplate increasing genetic diversity from a lower baseline in order to secure this value, I argue that this powerful intuition is more problematic than is generally recognized, especially where the price of diversity is the well-being of particular individuals. (shrink)

Currently, some of the most significant moral issues involving genetic links relate to genetic knowledge. In this paper, instead of looking at the frequently addressed issues of responsibilities professionals or institutions have to individuals, I take up the question of what responsibilities individuals have to one another with respect to genetic knowledge. I address the questions of whether individuals have a moral right to pursue their own goals without contributing to society's knowledge of population genetics, without adding (...) to their family's knowledge of its genetic history, and without discovering genetic information about themselves and their offspring. These questions lead to an examination of the presumed right to genetic ignorance and an exploration of a variety of social bonds. Analyzing cases in light of these considerations leads to a surprising conclusion about a widely accepted precept of genetic counseling, to some ethical insights into typical problems, and to some further unanswered questions about personal responsibility in the face of genetic knowledge. (shrink)

Genetic modification of crop plants is frequently described by its proponents as a continuation of the ancient process of domestication. While domestication, crop breeding, and GM all modify the genomes and phenotypes of plants, GM fundamentally differs from domestication in terms of the biological and sociopolitical processes by which change occurs, and the subsequent impacts on agrobiodiversity and seed sovereignty. We review the history of domestication, crop breeding, and GM, and show that crop breeding and GM are continuous with (...) each other in many important ways, but represent a momentous break from domestication because they move plant evolution off of farms and into centralized institutions. The social contexts in which these processes unfold dictate who holds rights to germplasm and agricultural knowledge, shape incentives to effect particular kinds of changes in our crops, and create or constrict biodiversity. Presenting GM as a continuation of domestication puts forward a false equivalency that fundamentally misrepresents how domestication, crop breeding, and GM occur. In doing so, this narrative diminishes public understanding of these important processes and obscures the effects of industrial agriculture on in situ biodiversity and the practice of farming. This misrepresentation is used in public-facing science communication by representatives of the biotechnology industry to silence meaningful debate on GM by convincing the public that it is the continuation of an age-old process that underlies all agricultural societies. (shrink)

Two families of mathematical methods lie at the heart of investigating the hierarchical structure of genetic variation in Homo sapiens: /diversity partitioning/, which assesses genetic variation within and among pre-determined groups, and /clustering analysis/, which simultaneously produces clusters and assigns individuals to these “unsupervised” cluster classifications. While mathematically consistent, these two methodologies are understood by many to ground diametrically opposed claims about the reality of human races. Moreover, modeling results are sensitive to assumptions such as preexisting theoretical commitments (...) to certain linguistic, anthropological, and geographic human groups. Thus, models can be perniciously reified. That is, they can be conflated and confused with the world. This fact belies standard realist and antirealist interpretations of “race,” and supports a pluralist conventionalist interpretation. (shrink)

We seek to develop a plausible conception of genetic parenthood, taking a recent discussion by Heidi Mertes as our point of departure. Mertes considers two conceptions of genetic parenthood—one invoking genetic resemblance, and the other genetic inheritance—and presents counter-examples to both conceptions. We revise Mertes’ second conception so as to avoid these and related counter-examples.

The purpose of this paper is to explore the impact that developments in transhumanist technologies may have upon human cultures, and to do so by exploring a potential debate between Habermas and the transhumanists. Transhumanists, such as Nick Bostrom, typically see the potential in genetic and other technologies for positively expanding and transcending human nature. In contrast, Habermas is a representative of those who are fearful of this technology, suggesting that it will compound the deleterious effects of the colonisation (...) of the lifeworld, further constraining human autonomy and undermining the meaningfulness of the lifeworld by expanding the technological control and manipulation of humanity. It will be argued that these opposed positions are grounded in fundamentally different understandings of the consequences of scientific and technological advance. On one level, the transhumanists remain confident that the lifeworld has within it the resources necessary to find meaning and purpose in a society deeply infused by genetic technology. Habermas disagrees. On another level, the difference is articulated by Horkheimer and Adorno in Dialectic of Enlightenment, primarily by challenging what may be understood as a Baconian faith in science as a project for the domination of nature. While the transhumanists broadly embrace this faith, Habermas returns to something akin to Horkheimer and Adorno’s pessimistic scepticism. (shrink)

Noninvasive prenatal testing promises to enhance women's reproductive autonomy by providing genetic information about the fetus, especially in the detection of genetic impairments like Down syndrome. In practice, however, NIPT provides opportunities for intensified manipulation and control over women's reproductive decisions. Applying Miranda Fricker's concept of epistemic injustice to prenatal screening, this article analyzes how medical professionals impair reproductive decision-making by perpetuating testimonial injustice. They do so by discrediting positive parental testimony about what it is like to raise (...) a child with DS. We argue that this testimonial injustice constitutes a twofold harm: people with DS and their family members who claim that parenting a child with DS may be a rewarding and joyous experience are harmed when they are systematically silenced, disbelieved, and/or denied epistemic credibility by medical professionals, and pregnant women are harmed since they might make poorly informed choices without access to all relevant information. The broader implication of the analysis is that epistemic justice is a precondition of reproductive autonomy. We conclude by calling for federal oversight of the acquisition and dissemination of information that prospective parents receive following a positive diagnosis of DS to ensure that it is comprehensive and up to date. (shrink)