This chapter contains sections titled: I II III.

This paper presents a personal view of the interaction between the analysis of choice under uncertainty and the analysis of production under uncertainty. Interest in the foundations of the theory of choice under uncertainty was stimulated by applications of expected utility theory such as the Sandmo model of production under uncertainty. This interest led to the development of generalized models including rank-dependent expected utility theory. In turn, the development of generalized expected utility models raised the question of (...) whether such models could be used in the analysis of applied problems such as those involving production under uncertainty. Finally, the revival of the state-contingent approach led to the recognition of a fundamental duality between choice problems and production problems. (shrink)

Two opposing accounts of early language evolution, the compositional and the holistic, have become the subject of lively debate. It has been argued that an evolving compositional protolanguage would not be useful for communication until it reached a certain level of grammatical complexity. This paper offers a new, discourse-oriented perspective on the debate. It argues that discourse should be viewed, not as a level of language structure ‘beyond the sentence’, but as sequenced communicative behaviour, typically but not uniquely involving language. (...) This provides for continuity from exchanges making use of simple communicative resources such as single words and gestures to those making use of complex grammatical conventions. Supporting evidence comes from child language and from original experiments with adults using constrained language systems. The paper shows that the utility of emerging compositional language is not dependent on some critical level of complexity, and so defends the compositional account. (shrink)

The purpose of this paper is to advance an analytical approach that systematically seeks to identify social mechanisms that generate and explain observed associations between events. In spite of recent contributions to animate the search for explanatory mechanisms, most of these monographs extol the theoretical while eschewing its application to applied research. This study emphasizes a systematic approach to identifying causal processes derived from critical realism by applying a realist template to research projects that claim to have identified causal mechanisms. (...) A critical realist framework serves as an independent standard in order to evaluate whether two proposed mechanisms, identified in applied research, adequately explain the phenomenon under study. The Disciplinary Revolution and The Familial State are used as sources of data since each work attempts to explain the emergence of the modern Dutch state yet by differing causal mechanisms. Realism’s approach to understanding causation emphasizes structural analysis which depends on abstract conceptualization in order to identify ontologically constituent properties, utilizes abductive and retroductive logic, and an emic interpretation of historical events. Findings suggest that research that intuitively emphasizes realist principles is more likely to identify causal processes. (shrink)

Scholars have recognized that contentious political action typically draws on relatively stable scripts for the enactment of claims making. But if such repertoires of political practice are generally reproduced over time, why and how do new modes of practice emerge? Employing a pragmatist perspective on social action, this article argues that change in political repertoires can be usefully understood as a result of situated political innovation—i.e., of the creative recombination of existing practices, through experimentation over time, by interacting political agents (...) for whom old repertoires were proving inadequate to the changing context of action. The utility of this approach is demonstrated by applying it to explain the historical emergence of a new set of populist mobilizing practices in early twentieth-century Peru. The results have implications for the study of political action and historical change. (shrink)

One aspect of the intellectual changes taking place in China in the late nineteenth and early twentieth centuries was the emergence of utilitarian ideas. Although it may be useful to think of modern Chinese thought from the perspective of the emergence of social Darwinism and nationalism, it is significant that the country's most progressive scholars at the turn of thecentury derived their inspiration from utilitarianism. Utilitarianism was accepted as a weapon with which to challenge traditional social, political, and (...) cultural ideas, and to justify social and political reforms. (shrink)

In the 1940s and 1950s, nuclear magnetic resonance , one of the most important analytical techniques in chemistry, grew to maturity in the intermediate research field of chemical physics. Chemists and physicists adapted the new technology to the experimental culture of molecular spectroscopy which was based on a pragmatic experimental style. In molecular spectroscopy, the purpose of experiments was the establishment of methods that suited both the physicists' quest for precision and theoretical model building and the chemists' longing for empirical (...) data and understanding of structural formulae and reaction courses. In this process, an experimental style emerged that can be characterized as reliance on self‐built instrumentation, theoretical foundation in quantum mechanics, and proof of utility in the solution of structural and dynamical questions. This article focuses on the early development of NMR at Harvard University, with particular emphasis on the contributions of the first chemist working in the field of NMR, Herbert S. Gutowsky. (shrink)

Natural language processing is a critical part of the digital transformation. NLP enables user-friendly interactions between machine and human by making computers understand human languages. Intelligent chatbot is an essential application of NLP to allow understanding of users’ utterance and responding in understandable sentences for specific applications simulating human-to-human conversations and interactions for problem solving or Q&As. This research studies emerging technologies for NLP-enabled intelligent chatbot development using a systematic patent analytic approach. Some intelligent text-mining techniques are applied, including document (...) term frequency analysis for key terminology extractions, clustering method for identifying the subdomains, and Latent Dirichlet Allocation for finding the key topics of patent set. This research utilizes the Derwent Innovation database as the main source for global intelligent chatbot patent retrievals. (shrink)

The aim of this article is to analyse the contemporary ‘futility discourse’ from a constructivist perspective. I will argue that bioethics discourse typically disregards the con text from which controversies emerge and the processes that inform and constrain such discourse. Constructivists have argued that scientific knowledge is expressive of the dominant paradigm within which a scientific community is working. I will outline an analysis of ‘medical futility’ as a construction of biomedical and bioethical communities (and their respective paradigms). I will (...) trace the emergence and utilization of futility in the literature. My analysis of the context (i.e. the historical circumstances, the particular actors involved) within which the futility discourse emerged suggests that medical futility was constructed, in part, as a means of enhancing physician domination of a context wherein medical authority was threatened. The actors in this debate express widely divergent frameworks of ‘the good’, arguing from distinctive representations of moral agency. At times, this controversy has been argued from incommensurate moral horizons wherein the discussants debate incomparable problems. This discussion is related to a study of the ‘practice’ of futility in the clinical context. Further studies on the construction of bioethical problems are a necessary condition for supporting the truth claims of bioethical arguments. (shrink)

In biosemiotics, life and living phenomena are described by means of originally anthropomorphic semiotic concepts. This can be justified if we can show that living systems as self-maintaining far from equilibrium systems create and update some kind of representation about the conditions of their self-maintenance. The point of view is the one of semiotic realism where signs and representations are considered as real and objective natural phenomena without any reference to the specifically human interpreter. It is argued that the most (...) basic concept of representation must be forward looking and that both C. Peirce’s and J. v. Uexküll’s concepts of sign assume an unnecessarily complex semiotic agent. The simplest representative systems do not have phenomenal objects or Umwelten at all. Instead, the minimal concept of representation and the source of normativity that is needed in its interpretation can be based on M. Bickhard’s interactivism. The initial normativity or natural self-interest is based on the ‘utility-concept’ of function: anything that contributes to the maintenance of a far from equilibrium system is functional to that system — every self-maintaining far from equilibrium system has a minimal natural self-interest to serve that function, it is its existential precondition. Minimal interactive representation emerges when such systems become able to switch appropriately between two or more means ofmaintaining themselves. At the level of such representations, a potentiality to detect an error may develop although no objects of representation for the system are provided. Phenomenal objects emerge in systems that are more complex. If a system creates a set of ongoingly updated ’situation images’ and can detect temporal invariances in the updating process, these invariances constitute objects for the system itself. Within them, a representative system gets an Umwelt and becomes capable of experiencing triadic signs. The relation between representation and its object is either iconic or indexical at this level. Correspondingly as in Peirce’s semeiotic, symbolic signs appear as more developed — for the symbolic signs, a more complex system is needed. (shrink)

The emergence of economic inequality has often been linked to individual differences in mental or physical capacities. By means of an agent-based simulation this paper shows that neither of these is a necessary condition. Rather, inequality can arise from iterated interactions of fully rational agents. This bears consequences for our understanding of both inequality and rationality. In a setting of iterated bargaining games, we claim that expected utility maximizing agents perform suboptimally in comparison with other strategies. The reason (...) for this lies in complex feedback effects between an agents’ action and the quality of beliefs used to calculate expected utility. Consequentially, we argue that the standard notion of rationality as maximizing expected utility is insufficient, even for certain standard cases of economic interaction. (shrink)

A rational basis can be found for dealing with the epistemology of the various futures' methodologies. According to "Conventionalism"—the modern school of philosophy of science, the main reason for preferring one science over another is its utility, rather than its authenticity. This means that according to "Conventionalism," which perceives the "utility" in the improvement of the psychic state and security of man as the main principle of any scientific thought, futures' methodologies, in their striving to achieve this end, (...) is no less a "science" than any other science. (shrink)

This paper explores the implications of the disjuncture between the real-world practice of governance and the popular understanding of politics. There are two ways of addressing this disjuncture. The first is to accept the popular conception of politics and declare its relative decline, alongside the state, in the face of supra-national governance. The second is to challenge the popular conception of politics and include governance in a new, broader definition. From the view that empirical social scientific concepts are judged in (...) terms of their utility, both to everyday discourse and to philosophical and theoretical discourses, a case is made for the second option. South African Journal of Philosophy Vol. 26 (3) 2007: pp. 289-305. (shrink)

Over the past decade, umbilical cord blood (UCB) has routinely been used as a source of haematopoietic stem cells for allogeneic stem cell transplants in the treatment of a range of malignant and non-malignant conditions affecting children and adults. UCB banks are a necessary part of the UCB transplant program, but their establishment has raised a number of important scientific, ethical and political issues. This paper examines the scientific and clinical evidence that has provided the basis for the establishment of (...) UCB banks. We also discuss the major ethical issues that UCB banks raise, including ownership of cord blood, processes for obtaining consent for its collection and storage, and confidentiality. Finally, we review other concerns about commercial non-altruistic banking, including concerns about social justice, equity of access and equity of care. (shrink)

Despite decades of research, we still lack a clear explanation for the emergence and persistence of inequality. Here we propose and evaluate a marginal utility of inequality hypothesis that nominates circumscription and environmental heterogeneity as independent, necessary conditions for the emergence of intragroup material inequality. After coupling the Standard Cross-Cultural Sample with newly generated data from remote sensing, we test predictions derived from this hypothesis using a multivariate generalized additive model that accounts for spatial and historical dependence (...) as well as subsistence mode. Our analyses show that the probability a society will be stratified increases significantly as a function of proxies of environmental heterogeneity and environmental circumscription. This supports the hypothesis that increasing environmental heterogeneity and circumscription drives the emergence and persistence of inequality among documented societies across the globe. We demonstrate how environmental heterogeneity and circumscription produce situations that limit individuals’ options so that some may find it in their best interest to give up some autonomy for material gain, while others may find it in their best interest to give up some material resources for another individual’s time or deference. These results support the marginal utility of inequality framework and enable future explorations of the ecological conditions that facilitate the emergence of intragroup inequality through time and across the globe. (shrink)

This article explores and critically evaluates the potential contribution to discourse studies of topic modelling, a group of machine learning methods which have been used with the aim of automatically discovering thematic information in large collections of texts. We critically evaluate the utility of the thematic grouping of texts into ‘topics’ emerging from a large collection of online patient comments about the National Health Service in England. We take two approaches to this, one inspired by methods adopted in existing (...) topic modelling research and the other using more established methods of discourse analysis. In the study, we compare the insights produced by each approach and consider the extent to which the automatically generated topics might be of use to discourse analysts attempting to organise and study sizeable datasets. We found that the topic modelling approach was able to group texts into ‘topics’ that were truly thematically coherent with a mixed degree of success, while the more traditional approach to discourse analysis consistently provided a more nuanced perspective on the data which was ultimately closer to the ‘reality’ of the texts it contains. This study thus highlights issues concerning the use of topic modelling and offers recommendations and caveats to researchers employing such approaches to studying discourse in the future. (shrink)

Electricity deregulation was meant to improve the quality of people’s lives by lowering the cost of a critical commodity. In every state that has chosen deregulation, however, power companies, free from the oversight of state regulators, have increased prices and, in California’s case, have driven a utility to bankruptcy. It is clear that deregulation was intended to benefit the energy industry more than consumers by removing cost-based regulations that restricted corporate profits but guaranteed low prices and reliable service to (...) consumers. Deregulation proponents argued that California’s commitment to strong air quality standards prevented development of adequate power plant construction and that not a single power plant was constructed in California in the 1990s. This claim is refuted through an examination of California Energy Commission data. Although other states’ experiences are not as dramatic as California’s, serious problems will emerge if deregulation continues to dominate the policy agenda. (shrink)

For more than a half-century, evidence scholars have been exploring whether the criminal standard of proof can be grounded in decision theory. Such grounding would require the emergence of a social consensus about the utilities to be assigned to the four outcomes at trial. Significant disagreement remains, even among legal scholars, about the relative desirability of those outcomes and even about the formalisms for manipulating their respective utilities. We attempt to diagnose the principal reasons for this dissensus and to (...) suggest ways in which a broadly shared evaluation might be forged, both with respect to the appropriate equations for defining the standard of proof and with respect to the appropriate utilities to associate with the various trial outcomes. Where consensus cannot be forged, we hold that remaining differences can probably be finessed. We also suggest ways to elicit the utilities of individuals on these matters so as to avoid the usual flaws of such surveys. Along the way, we note a). the disproportionate role that the Blackstone ratio of errors continues to play in appraisals of the utilities of trial outcomes (despite its unintelligibility in the context of utilities) and b). the persisting belief -for which there is no theoretical basis-that every plausible assignment of utilities will inevitably result in a very high standard of proof. Finally, we examine some of the technical features associated with a proposed rank ordering of the utilities of trial outcomes. (shrink)

This article focuses on emergency medical care in black urban populations, suggesting that the classification of a "community" within clinical trial language is problematic. The article references a cultural history of black Americans with pre-hospital emergency medical treatment as relevant to contemporary emergency medicine paradigms. Part I explores a relationship between "autonomy" and "community." The idea of community emerges as a displacement for the ethical principle of autonomy precisely at the moment that institutionalized medicine focuses on diversity. Part II examines (...) a clinical trial for the blood substitute PolyHeme® (Northfield Laboratories, Inc., Evanston, IL). It illustrates the ways in which bias in research paradigms and Institutional Review Board decisions attach to the notion and utility of the language of "community." The conclusion's contemporary anecdote makes apparent the vitality of the issues of prehospital emergency medical care and the ways in which decisions and practices fall too easily into a narrative of culturally biased treatment. (shrink)

The surprise minimization principle has been applied to explain various cognitive processes in humans. Originally describing perceptual and active inference, the framework has been applied to different types of decision making including long-term policies, utility maximization and exploration. This analysis extends the application of surprise minimization to a multi-agent setup and shows how it can explain the emergence of social rules and cooperation. We further show that in social decision-making and political policy design, surprise minimization is superior in (...) many aspects to the classical approach of maximizing utility. Surprise minimization shows directly what value freedom of choice can have for social agents and why, depending on the context, they enter into cooperation, agree on social rules, or do nothing of the kind. (shrink)

As members of the most evolutionarily developed species on earth, most of us share the common-sensical belief that our treatment of animals should be based more or less on moral grounds. However, it is also an undeniable fact that for more than two millennia, from the appearance of the first moral theories in Ancient Greece until almost the last quarter of the 20th century, this traditional moral concern for animals has gone hand in hand with their systematic exclusion from the (...) moral community of human beings, which deprives them of basic protective rights against moral abuse and mistreatment. A radical paradigm shift in ethics emerges, especially in the last quarter of the 20th century, when some philosophers begin to question this anthropocentric conception of ethics and the “otherness” of animals in terms of their traditional location outside the ethical discourse. Peter Singer, who is a utilitarian, and Tom Regan, who defends the “rights view” against Singer’s utilitarianism, are two prominent representatives of this new ethical approach. After showing how Singer and Regan reject speciesism, this paper focuses on Regan’s critique of Singer’s account and adds new objections that show that utilitarianism has serious general defects even if it is restricted to human beings. Moreover, these defects give rise to more complicated problems when utilitarianism is applied to animals. After pointing to some weak aspects in Regan’s theory, the paper spells out the sketch of an alternative account that points to the possibility of a synthesis of utility principle and right principle. Accordingly, Regan’s worse-off principle deduced from the rights view is interpreted as a formal principle, while the utility principle as the material content of it is accepted: as long as there is no violation of the worse-off principle, one ought to deduce particular commands to maximize utility for specific cases out of the application of the utility principle. In this context, the worse-off principle has only a negative and formal function that prevents the utility principle from overriding individual rights by giving it its obligatory form. (shrink)

In this paper I pour a little cold water on claims of global supervenience, not by arguing that they are false, and not by arguing that they possess no philosophical utility whatsoever, but by building a case for the following conditional conclusion: if you expect claims of global supervenience to play a certain role in a certain metaphysical project, then you will be disappointed, since they cannot play such a role. The metaphysical project is to give an illuminating and (...) suitably physicalist account of the relations between properties instantiated at different levels of reality. The paper makes a prima facie case for holding that claims of global supervenience can provide no illumination in such an account, a case that emerges when the metaphysics of global supervenience is probed a little more deeply than is customary. (shrink)

La recente esperienza dei movimenti “Occupy” e di altre proteste di strada evidenzia la domanda globale per una democrazia partecipativa che riconosca il conflitto sociale. L’emergere di un urbanismo insorgente a Tehran si è realizzato anche attraverso associazioni semantiche che dipendono dalla memoria storica presente nell’immaginazione collettiva. Durante la Rivoluzione Islamica del 1978-79, luoghi di Tehran quali Enqelab Street e Azadi Square hanno fornito le principali dimensioni spaziali della protesta rendendo possibile una sua appropriazione basata su nuove interpretazioni ideologiche. Inoltre, (...) le precedenti geografie della protesta a Tehran hanno fornito lo spazio primario per connettere gli attivisti con la gente comune e attivare una memoria collettiva inserita nel contesto urbano. Concentrandosi sulla Tehran moderna, questo articolo mira a elaborare un quadro teorico per comprendere le “piazze della protesta” come forme emergenti di spazio politico. In particolare, l’articolo si focalizza sul movimento “Take the square”, sviluppatosi a Tehran in anni recenti come un utile termine di paragone nel contesto della diffusione generale del fenomeno degli spazi urbani centrali che divengono “spazialita del malcontento”. (shrink)

This article focuses on emergency medical care in black urban populations, suggesting that the classification of a “community” within clinical trial language is problematic. The article references a cultural history of black Americans with pre-hospital emergency medical treatment as relevant to contemporary emergency medicine paradigms. Part I explores a relationship between “autonomy” and “community.” The idea of community emerges as a displacement for the ethical principle of autonomy precisely at the moment that institutionalized medicine focuses on diversity. Part II examines (...) a clinical trial for the blood substitute PolyHeme® (Northfield Laboratories, Inc., Evanston, IL). It illustrates the ways in which bias in research paradigms and Institutional Review Board decisions attach to the notion and utility of the language of “community.” The conclusion's contemporary anecdote makes apparent the vitality of the issues of prehospital emergency medical care and the ways in which decisions and practices fall too easily into a narrative of culturally biased treatment. (shrink)

The Dutch Book Argument for Probabilism assumes Ramsey's Thesis (RT), which purports to determine the prices an agent is rationally required to pay for a bet. Recently, a new objection to Ramsey's Thesis has emerged (Hedden 2013, Wronski & Godziszewski 2017, Wronski 2018)--I call this the Expected Utility Objection. According to this objection, it is Maximise Subjective Expected Utility (MSEU) that determines the prices an agent is required to pay for a bet, and this often disagrees with Ramsey's (...) Thesis. I suggest two responses to Hedden's objection. First, we might be permissive: agents are permitted to pay any price that is required or permitted by RT, and they are permitted to pay any price that is required or permitted by MSEU. This allows us to give a revised version of the Dutch Book Argument for Probabilism, which I call the Permissive Dutch Book Argument. Second, I suggest that even the proponent of the Expected Utility Objection should admit that RT gives the correct answer in certain very limited cases, and I show that, together with MSEU, this very restricted version of RT gives a new pragmatic argument for Probabilism, which I call the Bookless Pragmatic Argument. (shrink)

BackgroundUser selection is an important guarantee for the sustainable development of mobile medical businesses. Under the background of increasingly fierce competition, the decision-making behavior of mobile medical businesses will directly affect the choice of the behavior of users.MethodsThe study constructs the decision-making behavior model of mobile medical business based on the user choice and adds the role of people in government. It uses the game method to explore the relationship between the government, mobile medical business, and users. Finally, it makes (...) an example analysis. Empirical research is conducted to demonstrate the influence of different parameter changes on the results.ResultsThe results show that in the absence of government intervention, users’ choice of filtering information will create a bad environment for mobile medical businesses, and further will be reduced, and the expected utility of businesses will not be affected causing a reduction in expected utility of companies. Similarly, government regulations can effectively improve the mobile medical environment and enhance the expected utility of mobile medical companies.ConclusionThe government needs to formulate relevant laws and regulations to ensure the orderly operation of the mobile medical market and strengthen government supervision. It is necessary to conduct publicity and education to protect the fundamental interests of users and businesses. (shrink)

The emergence of key concepts in Reinhart Koselleck’s sense has been much discussed in conceptual history, but mainly for the eighteenth and nineteenth centuries. The article documents a post–World War II emergence of the concept of health, from relative anonymity to becoming a key concept, comparable to concepts such as politics, democracy, and culture. While previous research has emphasized conceptual mobility, this article focuses on conceptual aggregation, where the concept of health assembles and assimilates meanings, becoming essential to (...) discourse. This is explained with reference to the development of the welfare state and the political use of a positive, expanded health concept. The article utilizes a collocation analysis of Norwegian digitized newspapers 1950–2010, culled from the uniquely extensive database of the Norwegian National Library. (shrink)

Through a radical new reading of the Theological Political Treatise, Dimitris Vardoulakis argues that the major source of Spinoza’s materialism is the Epicurean tradition that re-emerges in modernity when manuscripts by Epicurus and Lucretius are rediscovered. This reconsideration of Spinoza’s political project, set within a historical context, lays the ground for an alternative genealogy of materialism. Central to this new reading of Spinoza are the theory of practical judgment (understood as the calculation of utility) and its implications for a (...) theory of democracy that is resolutely positioned against authority. (shrink)

Jürgen Habermas generally supports his theories not only by arguing for their transhistorical validity but also by demonstrating their critically reflexive understanding of their own emergence in history via a narrative of a select line of philosophers whose thought characterized their times. Habermas particularly uses such a narrative to support his conception of violence as that form of instrumental reason, increasingly pervasive in modern, rationalized societies, whereby, the actor is supposed to choose and calculate means and end from the (...) standpoint of maximizing utility or expectations of utility.... Media such as money and power attach to empirical ties;... (shrink)

In this paper, I argue for a new way of characterizing ontological emergence. I appeal to recent discussions in meta-ontology regarding fundamentality and dependence, and show how emergence can be simply and straightforwardly characterized using these notions. I then argue that many of the standard problems for emergence do not apply to this account: given a clearly specified meta-ontological background, emergence becomes much easier to explicate. If my arguments are successful, they show both a helpful way (...) of thinking about emergence and the potential utility of discussions in meta-ontology when applied to first-order metaphysics. (shrink)

In ‘Collapsing Emergence’, Elanor Taylor argues that all accounts of emergence face a common problem: excluding ‘collapse-inducing’ features—features encoding information about macro-level phenomena—from the micro-level bases of putatively emergent phenomena in a metaphysically principled way. I argue that Taylor's solution to ‘the collapse problem’, which utilizes an explanation-based account of emergence she develops in recent work, does not succeed, as it relies on a false principle about the requirements for explanation. I then propose a better solution, one (...) that presupposes no specific account of emergence, instead relying on the metaphysically principled distinction between what is essential to the having of a feature versus what is not. In addition to solving the collapse problem, I show how the distinction is also a useful tool for articulating more and less robust ways in which emergent phenomena can be genuinely novel and autonomous from the micro-level features they emerge from. (shrink)

In this article I examine Skinner's objections to mentalism. I conclude that his only valid objections concern the "specious explanations" that mentalism might afford ? explanations that are incomplete, circular, or faulty in other ways. Unfortunately, the mere adoption of behavioristic terminology does not solve that problem. It camouflages the nature of "private events," while providing no protection from specious explanations. I argue that covert states and events are causally effective, and may be sufficiently different in their nature to deserve (...) a name other than "behavior."To call such events"mental"does not force a dualistic metaphysics: Such a distinction can be easily assimilated by an "emergent behaviorism." Emergent behaviorism would make explicit use of theories. It would be inductive and pragmatic, and would evaluate hypothetical constructs in terms of their utility in clarifying and solving the outstanding problems of the discipline. (shrink)

Medical, scientific and societal progress has been such that, in a universalist humanist perspective such as the WHO’s, it has become an ethical imperative for the primary endpoints in evidence based health care research to be expressed in e.g. Quality Adjusted Life Years (QALYs). The classical endpoints of discrete health‐related functions and duration of survival are increasingly perceived as unacceptably reductionistic. The major problem in ‘felicitometrics’ is the measurement of the ‘quality’ term in QALYs. That the mental, physical and social (...) domains, each containing many dimensions and items, all contribute to QOL is uncontroversial. What is controversial, is the weight of the different dimensions in overall QOL. It has been shown to be very different between different patient populations. In human individuals, assuredly complex systems, the many dimensions and items of QOL observably interact, probably sometimes also in chaotic ways. In these conditions, the weights of isolated items in individuals become for all practical purposes meaningless. Therefore, the much used multi‐item questionnaires at best describe, but do not evaluate QOL, neither in individuals, nor in populations. For example, allergic patients treated with cetirizine scored better than those a placebo on all dimensions of the SF‐36, a standard QOL questionnaire. Here there is no serious doubt that the treatment improved QOL, because it is highly unlikely that any important dimension on which the patient groups would have scored otherwise is missing in the SF‐36. However, whether piracetam treatment of acute stroke, which improved the surrogate endpoints neurological and functional scores, also improved QOL is plausible, but will be proven only when comprehensive QOL measurement will have been done. And suppose in randomised populations of end‐stage metastatic solid cancer patients, one would compare palliative last‐line chemotherapy with only palliative care, and one would, as can be expected, find no significant differences in average survival, and chemotherapy superior for the mental domain, but inferior for the physical comfort domain: we would not know which treatment, on aggregate, would be the better. The problem is that QOL is an individual and emergent construct, the resultant of a great many intractions, and of a different order than its contributing components. Overall QOL can therefore best be captured only as the Gestalt of a global self‐assessment. Just as people in everyday life, while acting under uncertainty, make global assessments all the time, so they can seriously answer the serious question: ‘How have you been?’ A solemn, practical, non peer‐relativistic, non‐cultural, experiential, and well tolerated way to obtain such responses is Anamnestic Comparative Self Assessment (ACSA), in which the subjects' memories of the best and the worst times in their life experience define their individual scale of QOL. ACSA is thus both exquisitely idiosyncratic, and yet can in a universalist humanistic perspective be considered generic. Using both a multi‐item questionnaire and a global assessment allows by one logistic regression, to estimate the weights of the dimensions and items in populations, and thus identify those whose improvement would most contribute to the QOL of the greatest number. A combined approach to measurement of QOL is necessary to maximise the utility of QOL interventions. (shrink)

This exploratory study set out to pilot use of a Risk Innovation approach to support the development of advanced biopreservation technologies, and the societally beneficial development of advanced technologies more broadly. This is the first study to apply the Risk Innovation approach — which has previously been used to help individual organizations clarify areas of value and threats — to multiple entities involved in developing an emerging technology.

The paucity of research data to guide current paediatric practice has led to children being termed therapeutic orphans. This difficulty is especially pertinent to research in emergency situations, such as acute resuscitation or critical care, where accepted ethical standards for overall research, have historically created practical difficulties for researchers. The welcome establishment of organisations to support UK paediatric research is helping to ensure safer and more effective medications for children, however as the balance between protection and access at the heart (...) of the paediatric research ethical debate shifts to ever increasing access for researchers to children, it remains crucial to ensure the protection for these vulnerable participants. The fundamental protection for research subjects, namely their full informed consent before any recruitment, is not tenable in true emergency situations and so other approaches are warranted if standards are to be improved by human subjects research in such areas. Proxy, deferred and retrospective consent have all been advocated as solutions to this difficulty and this paper explores the ethical justification for these approaches and their utility in safeguarding children and families in emergency situations when traditional informed consent, as currently defined, cannot be obtained in the necessary time frame to enable research. (shrink)

Inappropriately reductive or deterministic appropriations of science haunt Philip Clayton’s otherwise instructive appropriation of Michael Polanyi’s thought for theological and ethical reflection. The work at hand utilizes contemporary complexity theory to augment Polanyi’s notions of emergence and hierarchy and to provide a vision within which moral responsibility and theological inquiry make sense. It sets forth types and orders of emergence that bypass untenable notions of causality, reducibility, and determinism.

In this paper, we conduct a secondary analysis of The Institute of Educational Sciences’ (IES) 2011-2012 Schools and Staffing Survey (SASS) data, a self-reported, nationally representative database to examine: (a) the average caseload of students with disabilities and emergent bilingual learners within and across social studies content areas, as well how social studies teachers’ caseloads compare with other content area disciplines and (b) the extent and perceived utility of professional development opportunities social studies teachers receive to support both students (...) with disabilities and emergent bilingual learners. (shrink)

Alexander the Great’s conquests ushered in the Hellenistic era throughout the ancient Mediterranean and Middle East. In this period, the Seleucids, one of most successful of the Successor dynasties, ruled over most of the Middle East at the height of their power. Yet two rising powers in the ancient world, Rome and Parthia, played a crucial role in the decline and eventual fall of the Seleucids. In a prior article, I argued that geopolitical developments around the Eastern Mediterranean in the (...) middle third century BCE were indirectly responsible for the emergence of the Parthian state in Iran. Disastrous military conflicts at home and abroad in the west caused a sudden decline of Seleucid power in the 240s–230s, triggering what political scientists call a power-transition crisis. This article utilizes similar approaches to historical analysis and International Relations theory to contend that, after a period of recovery, a further sudden decline of Seleucid power in the 160s–130s triggered another power-transition crisis that brought an end to Seleucid hegemony over the Middle East permanently. The crisis facilitated the rapid transformation of the Parthian state from a minor kingdom to a major empire, drastically changing the international environment of the ancient world. (shrink)

The dissertation is conceived as a major study of the controversial philosopher of world history, Oswald Spengler, as the exponent of a distinctive variety of political realism. The relationship of his ideas to German historicism and international theory is probed. The question of the historical inevitability of the eclipse of Europe by the ascendant superpowers and the epochal significance of the emergence of the American Century is considered in light of his philosophy. Spengler's many lectures and treatises on politics (...) are carefully examined in order to aid in harvesting his enduring wisdom on the art of statecraft, his insights into its ethical dilemma, and his reflections on the crisis of international politics in the twentieth century. The key thesis that Spengler transformed the cyclical philosophy he originally elaborated in his major work, The Decline of the West, summoning forth an arresting vision of world history as a soaring spiral culminating in the destruction of modern civilization, is buttressed through extensive quotation from posthumously published archival material. The actuality of his profoundly tragic thought, which illuminates the apocalyptic specter which haunts contemporary world affairs--the global ecological crisis, the cessation of economic growth in the overpopulated periphery and the danger of the collapse of the American-sponsored post-World War II international economic order, and the unending peril of a global war waged with thermonuclear, chemical, biological, and conventional weapons is explored. A provocative neo-Spenglerian scenario of the rapid deterioration of American economic power and the disintegration of the pax Americana, based on the classic analogy between Rome and America is adumbrated as an especially pessimistic contribution to the stormy debate about American "relative" decline. Finally, the significance of his philosophy to international political thought, particularly the utility of his pessimism in guiding statesmen in retarding the inevitable decline of the pax Americana as well as its value in exposing the guarded optimism at the core of "pessimistic" modern realist thought and in raising the question of its ultimate exhaustion in the face of the insurmountable crisis of modernity, is summarized. (shrink)

This paper examines the effects of non-derogability status for seven human rights during declared states of emergency from 1996 to 2004 in 195 countries. For this purpose, we create several original measures of countries’ state of emergency status. Our analysis finds the intended protections from the special legal status of non-derogable rights to be anemic, at best, during declared emergencies. This finding begs a reconsideration of both the utility of the “non-derogable” categorization in both international and municipal law, and (...) the conditions under which declared states of emergency might be justified. (shrink)

This rich and provocative study assesses Herbert Spencer's pivotal contribution to the emergence of liberal utilitarianism and shows that Spencer, as much as J. S. Mill, provided liberal utilitarianism with its formative contours. Like Mill, Spencer tried to reconcile a principle of liberty and strong moral rights with a utilitarian, maximizing theory of good. In this powerful and sympathetic account, David Weinstein argues that Spencer's moral and political thought exhibits greater systematic integrity than received views of his thought acknowledge. (...) However, Weinstein also examines the problems and flaws in Spencer's version of liberal utilitarianism, and shows that, precisely because of these flaws, it is engaging and deserving of our critical attention. This challenging study will be of interest to graduates and scholars in the fields of political theory, moral and political philosophy, and the history of political thought. (shrink)

After having explained why economics introduced utility functions and later the axioms about behaviour in a risky environment, the paper examines the interest for microeco-nomics of the concept of bounded rationality. It starts from a simple model of the labour market on which agents scarch and adapt their demands, contributing unconsciously to the emergence of a unique price. More complex models are thereafter introduced, which enables to draw a picture of the variety of possible trajectories in a dynamic (...) microeco-nomic system. This approach enables to enlarge microeconomics and to explain numerous facts poorly taken into account in the traditional presentations.Après avoir rappelé pourquoi la science économique avait introduit les fonctions d’utilité puis l’axiomatique des comportements en face du risque, l’article examine l’apport en microéco-nomie du concept de rationalité limitée. Il le fait à partir d’un modèle simple du marché du travail où les agents cherchent, et adaptent leurs exigences, contribuant, sous certaines hypothèses et sans en avoir conscience, à l’émergence d’un prix unique. Des modèles plus complexes sont ensuite examinés, ce qui permet de dresser un tableau de la variété des trajectoires possibles dans un système microéconomique dynamique. Cette approche permet d’élargir la théorie microéconomique en rendant compte de nombreux faits mal insérés dans la présentation traditionnelle. (shrink)

The essays in this volume offer a reassessment of Jeremy Bentham's strikingly original legal philosophy. Early on, Bentham discovered his 'genius for legislation' - 'legislation' included not only lawmaking and code writing, but also political and social institution building and engineering of public spaces for effective control of the exercise of political power. In his general philosophical work, Bentham sought to articulate a public philosophy to guide and direct all of his 'legislative' efforts. 0Part I explores the philosophical foundations of (...) his public philosophy: his theory of meaning and framework for analysis and definition of key concepts, his theory of human affections and motivations, and his utilitarian theory of value. It is argued that, while concepts of pleasure and happiness play nominal roles in his theory of value, concepts of publicity, equality, and interests emerge as the dominant concepts of his public philosophy. Part II explores several dimensions of Bentham's jurisprudence, including his radically revised command model of law, his early reflections on justice and law in adjudication, his theories of judicial evidence, constitutional rights, the rule of law, and international law. The concluding essay demonstrates the centrality of the notion of publicity in his moral, legal and political thought. Emerging from this study is a positivist legal theory and a utilitarian moral-political philosophy that challenge in fundamental ways contemporary understandings of those doctrines. (shrink)

Feeding difficulties in older patients who are suffering from dementia present problems with balancing conflicting ethical principles. They have been considered by several writers in recent years, and the views of nursing and care staff have been studied in different contexts. The present study used focus groups to explore the way in which nursing and care staff in a National Health Service trust deal with conflict between ethical principles in this area. Three focus groups were convened, one each from the (...) staff of three wards caring for patients with dementia. Case histories were discussed and transcripts analysed. It emerged that staff were aware of making fine judgements of utility concerning the spectrum of feeding methods available. Informants gave some weight to the principle of autonomy, but sought to balance that against their commitment to care. In explaining their perspectives, informants gave more weight to personal attitudes and trust culture than to professional ethics. (shrink)

This paper traces the origins of two technological trajectories in the contemporary history of wind power technology: the American Smith-Putnam Wind Turbine and the Danish Gedser Wind Turbine. Describing the two wind turbine projects in terms of their technical design characteristics, the professional background of the individuals involved, the organizational features of the technological knowledge production, and the historical context, the paper builds on the notion of technological trajectories in the making as a means of identifying emerging selection mechanisms for (...) possible engineering problem solutions, scientific methods, material artifacts, and financial assessment techniques. Conceived during the Great Depression and World War II, respectively, both projects promoted the idea that wind power could make a cost-effective contribution to the existing electric utility system. The two projects resulted in distinctive wind turbine innovations that paved the way for two technological trajectories in the contemporary history of wind power. Studying the emergence of technological trajectories, it is argued, requires the historian of technology to attend to well-known features of technological design and its cultural context that in retrospect appear to be significant, but also to tackle the creation of novelty and the inevitability of technological uncertainties about which the logic of trajectories has little to say. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 61.4 (2000) 617-634 [Access article in PDF] Edmund Burke and Reason of State David Armitage Edmund Burke has been one of the few political thinkers to be treated seriously by international theorists. 1 According to Martin Wight, one of the founders of the so-called "English School" of international theory, Burke was "[t]he only political philosopher who has turned wholly from political theory to (...) international theory." 2 The resurgence of interest in Burke as an international theorist has not, however, generated any consensus about how he might be classified within the traditions of international theory. Wight variously divided thinkers into trichotomous schools of Realists, Rationalists, and Revolutionaries, Machiavellians, Grotians, and Kantians, or theorists of international anarchy, habitual intercourse, or moral solidarity; 3 more recent international theorists have refined or supplemented these categories to construct similar trinitarian traditions of Realism, Liberalism, and Socialism, and of Empirical Realism, Universal Moral Order, and Historical Reason. 4 Burke's place within any of these traditions remains uncertain. Debate over whether he was a realist or an idealist, a [End Page 617] Rationalist or a Revolutionist, has concluded variously that he was a "conservative crusader" or an "historical empiricist," a belated dualist or a Cold Warrior before the fact, or, most egregiously, "a proto-Marxist, or more precisely proto-Gramscian" theorist of hegemony. 5 The fact that Burke so obviously eludes definition may put in doubt the analytical utility of closely-defined "traditions" of international theory. 6Burke's relationship to conceptions of reason of state provides a more precise example of the confusion within such taxonomies. According to one recent historian of international theory, Burke "laid the foundations" of the "conservative approach to International Relations informed by the two modern notions of state interest and necessity, by raison d'état"; however, in the words of another, "Burke... was vehemently opposed to the idea of Reason of State and did not subscribe to the view that national interests override moral laws." 7 The assumptions on which each of these judgments rests are clearly incompatible: on the one hand that a "conservative approach" in the realm of foreign affairs implies an espousal of reason of state defined as the primacy of "state interest and necessity," that Burke did indeed acknowledge; on the other hand that reason of state is defined more exactly as "the view that national interests override moral laws" and that Burke did not hold such a view, so could not be defined as a reason-of-state theorist. It might of course be possible that Burke held various views on such matters at various points in his long literary and political career or that he argued for differing conceptions of reason of state in differing contexts. To test such a hypothesis demands a historical account of Burke's relationship to the theories of reason of state held by his contemporaries and predecessors. [End Page 618]To place Burke within traditions of reason of state might seem to be a simple category error. After all, he famously scorned "dashing Machiavellian politicians," deplored "the odious maxims of a Machiavellian policy," condemned "the dreadful maxim of Machiavel that in great affairs men are not to be wicked by halves," and identified the Discorsi as the inflammatory textbook of French republicanism. 8 His strictures on Machiavelli and Machiavellianism affirmed avant la lettre the classic modern account of reason of state offered by Friedrich Meinecke, which counterposed "raison d'état on the one hand, and ethics and law on the other" and traced the emergence of this separation to the heathen Florentine who had given the tradition its familiar nickname. 9 Such accounts of reason of state and of Machiavelli reinforced the long-standing interpretation of Burke as the last of the medieval theorists of natural law, for whom no merely human calculations of advantage or interest could override the dictates of divine reason. If reason of state represented the doctrine that political expediency should supersede moral law, then Burke could only have been its (and Machiavelli's) enemy: his "politics... were grounded... (shrink)

In this paper we report a study of the approach of six U.K. water and electricity companies towards managing the relationship with their ''green'' stakeholders. Stakeholders are accorded increasing importance in political discourse and stakeholder theory is emerging as a promising framework for the analysis of corporate social performance.We studied the companies'' general approach towards green stakeholders, their dealings with specific stakeholder groups and whether they emphasised the consultation or the information aspect of stakeholder management. We found that none of (...) the six companies had a systematic stakeholder approach that extended to all potential green stakeholders. Rather, the importance of specific stakeholder groups seemed to be determined by managers'' intuition and by the stance that the stakeholders themselves displayed towards the company. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:72. HAS HUME A THEORY OF SOCIAL JUSTICE? Toward the end of An Enquiry concerning the Principles of Morals, Hume asserts in a footnote that: In short, we must ever distinguish between the necessity of a separation and constancy in men's possession, and the rules, which assign particular objects to particular persons. The first necessity is obvious, strong, and invincible : the latter may depend on a public (...) class='Hi'>utility more light and frivolous, on the sentiment of private humanity and aversion to private hardship, on positive laws, on precedents, analogies, and very fine connexions and. turns of the imagination. For one who draws the connection between the ideas of justice and possession as closely as he does, Hume's ambivalence here concerning the rules or principles governing the distribution of objects to be possessed is more than slightly surprising. In fact, for admirers of Hume interested in theories of social (or distributive) justice, his failure to state a preference among these various 'principles of distribution' is downright depressing. Is this all Hume has to say on the subject of how possessions are to be distributed within society? Does it not matter to him what the principles are upon which this distribution is accomplished — as long as it is accomplished? These are the questions with which this essay is concerned, questions which essentially reduce to that of whether Hume has a theoiy of social or distributive justice at all. To be sure;, the amount of space Hume devotes to the discussion of justice would seem to indicate that he is working from a particular theory of social justice, and authors such as Miller, Day, and Ardal ascribe one to him, yet Hume's apparent lack of concern for principles of distribution disputes this ascript- 73. 2 ion. For at the center of all such theories — from Aristotle to Rawls — lies a preference for a certain principle or set of principles which dictates how advantages (goods, wealth, benefits, etc.) should be distributed. In order to evaluate Hume's status as a theorist of social justice, two approaches recommend themselves. First, it is necessary to discover and examine in Hume's major works possible criteria which might dictate how possessions should be distributed in society. Three such criteria will be dealt with here: the principle of utility as Hume construes it, the formal principle of correct application of law, and the principles Hume entitles the laws of nature". If none of these emerge, singly or in combination, as the principle underlying a Humean theory of social justice, a second avenue for analyzing Hume's views of social justice will be explored. Here some of the critical psychological and moral characteristics which Hume attributes to human nature will be examined to determine whether Hume, though he seems to accept no specific principle of distribution, might arrive at a coherent theory of justice in a negative fashion; that is, through rejecting certain criteria of distribution, particularly merit and need. II. The half-heartedness of Hume's commitment to the principle of utility as either a standard of personal morality, a measure of the justness of particular actions, or as 4 an explanatory principle has been frequently documented, and, although the main purpose of this essay is to examine Hume's theory of social rather than personal justice, a few comments on the latter will form a useful preface for the subsequent argument that Hume is equally as luke-warm toward utilitarianism as an adequate basis of social justice. Three considerations indicate Hume's non-utilitarian approach to personal morality. First, unlike all advocates of utilitarianism, Hume is not a consequentialist on matters 74. of personal ethics. That is to say, when Hume speaks of what makes persons or their actions virtuous, he insists that the major criterion for such an evaluation is the motive upon which the agent acts. In the Treatise he states that a virtuous motive is requisite to render an action virtuous ; (T478), and maintains this view in the Enquiry as well. Hume therefore violates the consequentialist stance implicit in the utilitarian construal of personal morality, but just as seriously, is also left rather cold by the later utilitarian contention of Mill... (shrink)

In recent years, a number of authors have defended the coherence and philosophical utility of the notion of metaphysical indeterminacy. Concurrently, the idea that reality can be stratified into more or less fundamental ‘levels’ has gained significant traction in the literature. Here, I examine the relationship between these two notions. Specifically, I consider the question of what metaphysical determinacy at one level of reality tells us about the possibility of metaphysical determinacy at other more or less fundamental levels. Towards (...) this end, I propose a novel conception of the way in which fundamental states of affairs determine derivative states of affairs in the presence of indeterminacy and construct a corresponding formal model of multilevel systems that demonstrates the compatibility of determinacy at the fundamental level with indeterminacy at higher levels, thereby rebutting Barnes' suggestion that indeterminacy at any level of reality implies indeterminacy at the fundamental level. (shrink)