Aim: The present work proposes the study of the neuromotor activity of the masseter-jaw-tongue articulation during diadochokinetic exercising to establish functional statistical relationships between surface Electromyography, 3D Accelerometry, and acoustic features extracted from the speech signal, with the aim of characterizing Hypokinetic Dysarthria. A database of multi-trait signals of recordings from an age-matched control and PD participants are used in the experimental study. Hypothesis: The main assumption is that information between sEMG and 3D acceleration, and acoustic features may be quantified (...) using linear regression methods. Methods: Recordings from a cohort of eight age-matched control participants and eight PD participants were collected during the utterance of a diadochokinetic exercise. The dynamic and acoustic absolute kinematic velocities produced during the exercises were estimated by acoustic filter inversion and numerical integration and differentiation of the speech signal. The amplitude distributions of the absolute kinematic and acoustic velocities are estimated to allow comparisons in terms of Mutual Information. Results: The regression results show the relationships between sEMG and dynamic and acoustic estimates. The projection methodology may help in understanding the basic neuromotor muscle activity regarding neurodegenerative speech in remote monitoring neuromotor and neurocognitive diseases using speech as the vehicular tool, and in the study of other speech-related disorders. The study also showed strong and significant cross-correlations between articulation kinematics, both for the control and the PD cohorts. The absolute kinematic variables presents an observable difference for the PD participants compared to the control group. Conclusion: Kinematic distributions derived from acoustic analysis may be useful biomarkers toward characterizing HD in neuromotor disorders providing new insights into PD. (shrink)

O presente artigo objetiva, ao revisitar a obra Oratio de hominis dignitate composta pelo humanista renascentista Giovanni Pico Della Mirandola, um duplo intento: sustentar que as noções de dignidade e liberdade, presentes nessa obra, se distanciam do pensamento cristão tradicional, de modo crítico, justamente porque derivam de uma leitura filosófica da teologia cristã da criação; e mostrar que a conclusão a respeito da noção de liberdade apresentada por Sartre no pensamento contemporâneo pode ser encontrada de modo germinal, guardada as devidas (...) proporções, na leitura piquiana da criação. Para tanto, exporemos uma breve retomada do contexto histórico-filosófico que permitiu ao filósofo engendrar a Oratio bem como suas pretensões para com essa obra; falaremos, em um segundo momento, como o platonismo religioso de Marsílio Ficino, principal matriz teórica a partir do qual os conceitos de dignidade e de liberdade foram modulados, foi recebido e desenvolvido no pensamento de Pico; e como as influências e as rupturas com pensamento de Ficino e a leitura filosófica da teologia cristã da criação são importantes para recolocar os conceitos de dignidade e de liberdade, permitindo assim entrever, por meio deles, semelhanças com o pensamento satreano. (shrink)

Problems and choices -- Who shall live? -- The physician : the captain of the team -- The hospital : the house of hope -- Drugs : the key to modern medicine -- Paying for medical care.

In this paper I argue that the existence of human reason gives us good reason to suppose that God exists. If the world were as the materialist supposes it is, then we would not be able to reason to the conclusion that this is so. This contention is often challenged by the claim that mental and physical explanations can be given for the same event. But a close examination of the question of explanatory compatibility reveals that the sort of explanation (...) that would have to be given for the event of, say, inferring that atheism is true, is incompatible with the event being explicable as a purely physical product of a purely physical universe. (shrink)

Abstract.The United States today is faced with a crisis of the liberal system stemming from a shortage of resources and ideas. Liberalism assumes that there will always be enough resources to meet all needs and that politics consists of the struggle of interest groups for resources to meet their particular needs. Liberalism is wrong on both counts: there are not enough resources and there is a common good which includes all particular needs properly understood. We must now revise our ideas (...) and institutions in order to make the common good attainable. Various changes in ideas and institutions toward that end are suggested. (shrink)

Amsterdam University Press is a leading publisher of academic books, journals and textbooks in the Humanities and Social Sciences. Our aim is to make current research available to scholars, students, innovators, and the general public. AUP stands for scholarly excellence, global presence, and engagement with the international academic community.

Amsterdam University Press is a leading publisher of academic books, journals and textbooks in the Humanities and Social Sciences. Our aim is to make current research available to scholars, students, innovators, and the general public. AUP stands for scholarly excellence, global presence, and engagement with the international academic community.

_On Tyranny_ is Leo Strauss’s classic reading of Xenophon’s dialogue _Hiero_, or _Tyrannicus_, in which the tyrant Hiero and the poet Simonides discuss the advantages and disadvantages of exercising tyranny. Included are a translation of the dialogue from its original Greek, a critique of Strauss’s commentary by the French philosopher Alexandre Kojève, and the complete correspondence between the two. This revised and expanded edition introduces important corrections throughout and expands Strauss’s restatement of his position in light of Kojève’s commentary to (...) bring it into conformity with the text as it was originally published in France. (shrink)

There is an unresolved conflict concerning the normative nature of desire. Some authors take rational desire to differ from rational belief in being a normatively unconstrained attitude. Others insist that rational desire seems plausibly subject to several consistency norms. This article argues that the correct analysis of this conflict of conative normativity leads us to acknowledge intrinsic and extrinsic reasons to desire. If sound, this point helps us to unveil a fundamental aspect of desire, namely, that we cannot desire at (...) will. Unlike belief, however, desire can unproblematically accommodate a notion of instrumental attitude. (shrink)

This book examines leadership strategies that allow administrators to be proactive, visionary, and flexible while increasing collaboration, open communication, and closely integrating theory and practice to ensure successful administration in higher education settings.

El propósito de la presente nota crítica consiste en examinar la concepción que Leo Strauss y José Ortega y Gasset elaboraron de la historia de la filosofía. Se trata, por tanto, de explorar la imagen que presentaron de dicha historia, una imagen de carácter general y que no repara en aspectos concretos. En la primera parte exponemos la concepción straussiana de la historia de la filosofía. En la segunda parte nos ocupamos de la concepción orteguiana de la historia de la (...) filosofía. Para concluir realizamos un análisis comparativo de una y otra concepción. (shrink)

Sometimes Strauss argues as if he thought it possible to understand man without raising questions about his relations to other things, and hence about his place in the whole. But when they are viewed in their broader context, such arguments are seen not to be his final word. Man's humanity cannot be understood in its own terms alone. The human soul differs from everything else in that it is "... open to the whole and therefore more akin to the whole (...) than anything else is." In ordinary usage, "whole" implies completeness and autonomy. But the openness of the soul--i.e., of a part--to the whole can only mean that the whole is open to itself. The whole is, then, not, in the ordinary sense of the term, whole. Nor is the soul which is "open" to it. Stripped of myths, "... the human soul is... more akin to the whole than anything else is" because neither of them is whole. The same conclusion follows when one tries to understand the definition of the philosopher as the man animated by quest for knowledge of the whole. Qua philosopher he knows neither that there is a whole, nor what it might be if there were one. To define the philosopher as the man who knows that he does not know only paraphrases the difficulty. It does not solve it. For "know" is here used equivocally. The same equivocation is at play in the comment "... one cannot know that one does not know without knowing what one does not know". Admittedly "knowledge of ignorance is not ignorance." The philosopher believes and perhaps divines more than he actually knows. All men do. The essential difference between the philosopher and other men may well consist in the fact that the philosopher distinguishes more conscientiously than do others between what he knows and what he believes, and that he strives more single-mindedly than do they to transform as large a share of his beliefs as possible into knowledge. He may conceivably at some point be said to have reached the stage where his aspirations have become reasoned expectations. But that is as far as he can possibly go as long as he remains a philosopher and has not become a wise man or a god. Until and unless the philosopher knows, in the strong sense of the term, he can no more decide whether his aspirations could be fulfilled than he can swim before getting wet. (shrink)

The anthropic coincidences are widely claimed to provide evidence for intelligent creation in the universe. However, neither data northeory support this conclusion. No basis exists for assuming that a random universe would not have some kind of life. Calculations of the properties of universes having different physical constants than ours indicate that long-lived stars are not unusual, and thus most universes should have time for complex systems of some type to evolve. A multi-universe scenario is not ruled out, since no (...) known principle requires that only one universe exist. (shrink)

This article attempts to re-establish the importance of Foucault's work for an understanding of the way in which modern law operates. This argument has two stages. Firstly, there is a critique of the interpretation of Foucault's work by legal and sociological thinkers. It is argued that by reading the term ‘juridical’ as synonymous with the term ‘law’ in Foucault, people miss the substance of Foucault's argument. The term juridical describes an arrangement and a representation of power rather than the law. (...) This is made clear through a critique of J. S. Mill's On Liberty which is shown to make a juridical distinction between power and a free space of action which is unsustainable. Secondly, Foucault's genealogy of power relations is recast from the perspective of a legal theoretician. Foucault's history of power relations is constructed from historical differences in the mode of operation of power and discourse. By analysing these differences and their relationship to the mode of operation of law, an account of the place of modern law in Foucault's genealogy is established. Modern law operates between Foucault's concepts of government and discipline. It provides a key way in which government decisions can adjust the relationships between disciplinary institutions. This introduces the idea that law begins to operate in the perspective of the complete lives of individuals rather than just to prevent certain actions. Law, then, operates in accordance with what Foucault calls ‘bio-power’. (shrink)