Explores the understanding of self-consciousness and personal identity - two fundamendtal features of human subjectivity - as it developed in early modern philosophy. Udo Thiel presents a critical evaluation of these features as they were conceived in the sevententh and eighteenth centuries. He explains the arguments of thinkers such as Descartes, Locke, Leibniz, Wolff, and Hume, as well as their early critics, followers, and other philosophical contemporaries, and situates them within their historical contexts. Interest in the issues of self-consciousness and (...) personal identity is in many ways characteristic [of] and even central to early modern thought, but Thiel argues here that this is also an interest that continues to this day, in a form still strongly influenced by the conceptual frameworks of early modern thought. In this book he attempts to broaden the scope of the treatment of these issues considerably, covering more than a hundred years of philosophical debate in France, Britain, and Germany while remaining attentive to the details of the arguments under scrutiny and discussing alternative interpretations in many cases"--Publisher's description, p. [4] of dust jacket. (shrink)

We describe a number of conscientious objection cases in a liberal Western democracy. These cases strongly suggest that the typical conscientious objector does not object to unreasonable, controversial professional services—involving torture, for instance—but to the provision of professional services that are both uncontroversially legal and that patients are entitled to receive. We analyse the conflict between these patients' access rights and the conscientious objection accommodation demanded by monopoly providers of such healthcare services. It is implausible that professionals who voluntarily join (...) a profession should be endowed with a legal claim not to provide services that are within the scope of the profession's practice and that society expects them to provide. We discuss common counterarguments to this view and reject all of them. (shrink)

This paper makes a conceptual inquiry into the notion of ‘publics’, and forwards an understanding of this notion that allows more responsible forms of decision-making with regards to technologies that have localized impacts, such as wind parks, hydrogen stations or flood barriers. The outcome of this inquiry is that the acceptability of a decision is to be assessed by a plurality of ‘publics’, including that of a local community. Even though a plurality of ‘publics’ might create competing normative demands, its (...) acknowledgment is necessary to withstand the monopolization of the process of technology appraisal. The paper presents four ways in which such an appropriation of publicness takes place. The creation of dedicated ‘local publics’, in contrast, helps to overcome these problems and allows for more responsible forms of decision-making. We describe ‘local publics’ as those in which stakeholders from the different publics that are related to the process of technology implementation are brought together, and in which concerns and issues from these publics are deliberated upon. The paper will present eight conditions for increasing the effectiveness of such ‘local publics’. (shrink)

Der Verf. beschreibt die Einstellung Alberts zur Alchemie und die verschiedenen Phasen seiner Auseinandersetzung mit dieser ars. Alberts naturwissenschaftliche Schriften haben prozessualen Charakter. Er rezipiert alchemische Literatur seit der Mitte der 40er Jahre und sucht nach einem philosophischen Fundament zur Sicherung der neuen Wissenschaft. Grundlage ist für ihn die aristotelische Naturphilosophie. Nachdem er im Frühwerk De quattuor coaequaevis das Problem der Materie generell diskutiert und die über Augustin rezipierten platonischen Positionen zugunsten einer aristotelisch gestützten Theorie verworfen hatte, wird seit dem (...) Sentenzenkommentar die Transmutation ausführlich diskutiert, . Albert, dessen Positionen erkennbar an den Schriften des Avicenna orientiert sind, weist die Ansätze zeitgenössischer Alchemisten zurück, die eine antimetaphysische und materialistische Grundhaltung vertreten und damit gleichsam Ansätze zu einer autonomen Naturwissenschaft zeigen. Er kritisiert zudem die mangelnde Qualität der Produkte der künstlichen Transmutation und ihre fehlende geheime Wirksamkeit im Verhältnis zu den naturalia. Dennoch hat Albert ein differenziertes Bild von der Alchemie. Ihn interessiert allerdings weniger die praktische Nützlichkeit als ihr Stellenwert im Kontext der Naturphilosophie. - Der Verf. druckt die einschlägige Stelle aus Alberts Sentenzenkommentar ab und kommentiert sie ausführlich. (shrink)

Bioethics, Volume 36, Issue 1, Page 1-2, January 2022.

Knowing that technologies are inherently value-laden and systemically interwoven with society, the question is how individual engineers can take up the challenge of accepting the responsibility for their work? This paper will argue that engineers have no institutional structure at the level of society that allows them to recognize, reflect upon, and actively integrate the value-laden character of their designs. Instead, engineers have to tap on the different institutional realms of market, science, and state, making their work a ‘hybrid’ activity (...) combining elements from the different institutional realms. To deal with this institutional hybridity, engineers develop routines and heuristics in their professional network, which do not allow societal values to be expressed in a satisfactory manner. To allow forms of ‘active’ responsibility, there have to be so-called ‘accountability forums’ that guide moral reflections of individual actors. The paper will subsequently look at the methodologies of value-sensitive design and constructive technology assessment and explore whether and how these methodologies allow engineers to integrate societal values into the design technological artifacts and systems. As VSD and CTA are methodologies that look at the process of technological design, whereas the focus of this paper is on the designer, they can only be used indirectly, namely as frameworks which help to identify the contours of a framework for active responsibility of engineers. (shrink)

Dieser Band stellt Abhandlungen von Udo Müllges (1926-1985), Universitätsprofessor an der RWTH Aachen, vor, die in ihrer Gesamtheit ein pädagogisches Programm spiegeln, das auf der geisteswissenschaftlichen Tradition fußt und sich dieser verpflichtet weiß. Der Bogen ist von der konstitutiv-kritischen Frage nach dem Wissenschaftscharakter der Pädagogik bis hin zu aktuellen schulpolitischen Problemen gespannt. In ihrer Gesamtheit bieten die Beiträge einen Einblick in das breite Feld pädagogischer Forschung und eröffnen die Möglichkeit zur produktiven Auseinandersetzung mit den von Udo Müllges erarbeiteten Konzepten zur (...) Klärung gegenwärtiger theoretischer und praktischer Fragen. Das Buch bietet gleichermaßen Anregungen für Fachkollegen, Studierende und Praktiker des pädagogischen Bereiches. (shrink)

Dr. Udo Lenzig ist Schulreferent im Kirchenkreis Julich.

In a commentary published in Bioethics I defended Qatar as the location of the 2024 World Congress of Bioethics (Schuklenk 2023). I have since, reluctantly, changed my views on this.This brief resp...

Recent economic and political advances in developing countries on the African continent and South East Asia are threatened by the rising death and morbidity rates of HIV/AIDS. In the first part of this paper we explain the reasons for the absence of affordable access to essential AIDS medication. In the second part we take a closer look at some of the pivotal frameworks relevant for this situation and undertake an ethical analysis of these frameworks. In the third part we discuss (...) a few of the proposed solutions to the problem and conclude with an argument in support of our preferred course of action. In this article we argue for compulsory licensing of essential AIDS medications in the current conditions of public health emergency. We argue on broadly consequentialist grounds that compulsory licensing is preferable both morally and pragmatically to the alternatives, notably the currently offered price cuts and drug donation schemes. (shrink)

Healthcare professionals’ capacity to protect themselves, while caring for infected patients during an infectious disease pandemic, depends on their ability to practise universal precautions. In turn, universal precautions rely on the availability of personal protective equipment (PPE). During the SARS-CoV2 outbreak many healthcare workers across the globe have been reluctant to provide patient care because crucial PPE components are in short supply. The lack of such equipment during the pandemic was not a result of careful resource allocation decisions in the (...) global north, where the short supply could be explained through their high cost. Instead, they were the result of democratically elected governments prioritising low tax regimes over an adequate resourcing of their healthcare delivery systems. Such decisions were made despite global health experts warning about the high probability of pandemics like SARS-CoV2 occurring during our lifetimes. Avoidable allocation decisions by democratically elected political leaders resulted in a lack of sufficient PPE for healthcare professionals. After discussing and discounting various ethical arguments in support of a professional obligation to treat, even without or with suboptimal PPE, I conclude that these policy decisions were sufficiently grave that they provide a sound ethical rationale to justify healthcare workers’ refusal to provide care to infected patients. (shrink)

Emotions are often met with suspicion in political debates about risky technologies, because they are seen as contrary to rational decision making. However, recent emotion research rejects such a dichotomous view of reason and emotion, by seeing emotions as an important source of moral insight. Moral emotions such as compassion and feelings of responsibility and justice can play an important role in judging ethical aspects of technological risks, such as justice, fairness, and autonomy. This article discusses how this idea can (...) be integrated into approaches for political decision making about risk. The article starts with an analysis of the dichotomous view of reason and emotion in risk theory, in approaches to participatory risk assessment as well as in relevant approaches to political philosophy. This article then presents alternative approaches in political philosophy and political theory that do explicitly endorse the importance of emotions. Based on these insights, a procedural approach for policy making is presented, in which emotional responses to technological risks, and the ethical concerns that lie behind them, are taken seriously. This approach allows for morally better political decisions about risky technologies and a better understanding between experts and laypeople. (shrink)

New network technologies are framed as eliminating ‘transaction costs’, a notion first developed in economic theory that now drives the design of market systems. However, the actual promise of the elimination of transaction costs seems unfeasible, because of a cyclical pattern in which network technologies that make that promise create processes of institutionalization that create new forms transaction costs. Nonetheless, the promises legitimize the exemption of innovations of network technologies from critical scrutiny.

It is a great loss to philosophy that Heraclitus’s writing was lost in antiquity, for the surviving fragments rarely contain more than one sentence. Often, they are succinct but concise statements that contain little text. So, when one succeeds in augmenting important fragments with a few words or illuminating their context, there is progress in Heraclitus research. Sometimes, however, this requires recourse to lineages outside the Greek-Latin tradition. An example of this is provided by fragment 123, which has played an (...) important role since its discovery in the Orationes of Themistius: in the 20th century, Martin Heidegger used it several times for his idiosyncratic interpretation of Heraclitus and the philosophy of the Pre-Socratics. However, he did not consider that an Armenian variant of this fragment had become available at the beginning of the 19th century. This Armenian variant derives from a treatise of Philo of Alexandria which has only been transmitted in Armenian and offers more text than the Greek version. As Diels-Kranz did not include this Armenian source in their edition of The Fragments of the Pre-Socratics, this Armenian variant fell into oblivion and was not known to Heidegger either. Now this article, after introductory remarks on the transmission of Heraclitus’s sayings in Themistius and Philo’s Heraclitea, focuses on the history of the Armenian version of fragment 123 and its primary interpretations. It concludes with a reconstruction of the remarks which Ferdinand Lassalle dedicated to this fragment in both its Greek and Armenian versions in 1858. (shrink)

Zusammenfassung a. Angeregt von den Hinweisen aus dem armenischen Kloster in St. Lazzaro, bemerkten einige, auf die kaukasischen Hochkulturen spezialisierte europäische Orientalisten, die Rezeption der proklischen Philosophie in Armenien. 1874, nach fast fünfzig Jahren Forschungsarbeit, standen folgende Ergebnisse fest: I. Im 9. Jahrhundert übersetzte der Georgier Petrizi die Στοιχείωσις θεολογική ins Georgische und fügte Kommentare hinzu. Diese Vorlage nutzte der Armenier Simeon für eine erste armenische Übersetzung des proklischen Opusculums. Später, in der Frühen Neuzeit, erkannte dann ein anderer armenischer Gelehrter, (...) der ebenfalls den Namen Simeon‘ trug, die Fehler dieser ersten Translation, verbesserte sie und verfasste ebenfalls einen Kommentar dazu. Handschriften dieser zweiten Fassung befanden sich in Westeuropa sowie in armenischen Klöstern. b. Eine umfangreiche Auseinandersetzung mit den armenischen Procliana fand in Europa allerdings nicht statt. Die Ursache für diese verpasste Gelegenheit liegt vor allem am mangelnden Interesse an einem vertieften Studium der armenischen Philosophie und an fehlenden philologischen Fachkenntnissen. Nur C. F. Neumann kann dabei als Ausnahme gelten. Er wäre aufgrund seiner philosophischen und philologischen Ausbildung zu einer qualifizierten Auswertung der armenischen Procliana in der Lage gewesen. Er suchte sogar nach diesen Materialien, aber seine Recherchen führten nicht zum gewünschten Erfolg. Später verlor er die Philosophie der Armenier aus den Augen und überließ das Feld anderen. Deren Kenntnis des Proklos und seiner Philosophie hielt sich dagegen in engen Grenzen und ging nicht über die Informationen lexikalischer Handbücher hinaus. Das entsprach dem Geist der Zeit, die im Neuplatonismus keine bedeutende philosophische Strömung sah. Dennoch führten diese Untersuchungen zu Einsichten in die Geschichte der armenischen Philosophie. c. Die armenischen Procliana standen im 19. Jahrhundert niemals im Mittelpunkt der Forschung. Daran hat sich bis heute kaum etwas geändert. Ein Umdenken kann jedoch nur dann gelingen, wenn sich die Erkenntnis durchsetzt, dass auch Translationen als Dokumente der interkulturellen Philosophie eine hohe Bedeutung besitzen und die Rekonstruktion derartiger Transfers zu wichtigen Ergebnissen führt; Übersetzungen verknüpfen nicht nur Sprachwelten, sondern auch differente Weltdeutungen. Die armenischen Procliana bestätigen jedenfalls die These, dass die Auffassung von separaten philosophischen Traditionen in Armenien und Georgien nur bedingt Gültigkeit besitzt. (shrink)

In den pseudo-dionysischen Schriften bleibt die konkrete Kunsterfahrung ihres syrischen Autors schwer faßbar, doch zeigt sich ein spezifisches Kunstinteresse. An zahlreichen Stellen wird die anagogische Funktion des schönen Kirchenraums, der schönen Liturgie, Musik und Sprache thematisiert. Es zeigt sich, daß Dionysios' philosophische Terminologie nach ästhetischen Gesichtspunkten konstruiert ist.

This paper was presented at the Engineering Foundation Conference on “Ethics for Science and Engineering Based International Industries”, Durham, NC, USA, 14–17 September 1997. An earlier version of this paper appeared in OECD’s STI Review No. 21, 1998, OECD. The Organisation for Economic Co-operation and Development is an international organization founded in 1961 to stimulate economic progress and world trade. Information at [email protected].

50 Voices of Disbelief: Why We Are Atheists presents acollection of original essays drawn from an international group ofprominent voices in the fields of academia, science, literature,media and politics who offer carefully considered statements of whythey are atheists. Features a truly international cast of contributors, rangingfrom public intellectuals such as Peter Singer, Susan Blackmore,and A.C. Grayling, novelists, such as Joe Haldeman, and heavyweightphilosophers of religion, including Graham Oppy and MichaelTooley Contributions range from rigorous philosophical arguments tohighly personal, even whimsical, accounts (...) of how each of thesenotable thinkers have come to reject religion in their lives Likely to have broad appeal given the current publicfascination with religious issues and the reception of such booksas The God Delusion and The End of Faith. (shrink)

Der Gottinger Philosoph, Politiker und Padagoge Leonard Nelson (1882-1927) entwickelte eine umfassende integrale Theorie, die sich von der philosophischen Grundlegung uber eine Gesellschaftsanalyse bis zu einer politischen Programmatik hin erstreckte.Mit diesem Werk liegt eine erste umfassende, auf neuen Quellen basierende kritische Gesamtdarstellung der politischen Theorie Nelsons vor. Neben der Darstellung der Biographie Nelsons entwickelt der Autor dessen neukantianische Philosophie. In der Gesellschaftstheorie wird die Auseinandersetzung mit Liberalismus, Sozialismus und Kommunismus deutlich.Die Monographie basiert auf ausfuhrlichen Quellenstudien und bezieht eine kritische analysierende (...) Grundposition.Sie richtet sich an Historiker und Philosophen ebenso wie Politologen und politisch Interessierte allgemein.Der Verfasser lehrt als Privatdozent fur Politikwissenschaft an der Universitat Dortmund und hat mehrere historisch-politische Studien veroffentlicht. (shrink)

The COVID-19 pandemic brought about at least two normative challenges on unprecedented scale for liberal democracies. One concerned prioritization decisions when health care resources were constrained. The other, which arguably led to lasting damage to social cohesion and citizens’ trust in government and government public health institutions, concerned policies introduced with the aim of reducing the spread of SARS-CoV2, some of which turned out to be mistaken. I discuss in this essay a few examples of misguided, liberty-limiting public health policies (...) and describe how public health and public health ethics principlism provided cover for such policies. Citizens had reasons to be concerned about the duration of such liberty-infringing policies, the absence of predictable government policies, and the absence of transparent justifications for the policies that were implemented. (shrink)

Religious considerations and language do not typically belong in the professional advice rendered by a doctor to a patient. Among the rationales mounted by Greenblum and Hubbard in support of that conclusion is that religious considerations and language are incompatible with the role of doctors as public officials.1 Much as I agree with their conclusion, I take issue with this particular aspect of their analysis. It seems based on a mischaracterisation of what societal role doctors fulfil, qua doctors. What obliges (...) doctors to communicate by means of content that is expressed in public reason-based language is not that they are public officials. Doctors as doctors are not necessarily public officials. Rather, doctors have such obligations, because they are professionals. Unlike public officials doctors are part of a profession that is to a significant extent self-governing. This holds true for all professions. The …. (shrink)

Between Wolff and Kant: Merian's Theory of Apperception UDO THIEL IT IS WELL KNOWN that the nodon of apperception or self-consciousness is central to Kant's theoretical philosophy. Kant introduces the notion in one of the crucial parts of the Critique of Pure Reason, the Transcendental Deduction of the Categories, and assigns it an important role in his critique of traditional metaphysics of the soul in the Transcendental Dialectic.' It is also well known that Kant did not invent the term "apperception." (...) Leibniz had introduced the French 'Tapperception" into philosophical terminology early in the eigh- teenth century. Kant scholars generally stress, rightly, that Kant's notion of apperception differs significandy from that of his predecessors. However, the precise relation between Kant's concept of apperception and earlier accounts has not been considered in any detail. Wolfgang Carl, for example, simply states that the main difference is that, prior to Kant, apperception was under- stood as relating only to mental acts and their contents, and not to the subject that thinks and has ideas, whereas in Kant apperception relates essentially to the thinking subject. 2 This very general thesis is questionable even in regard to some of the philosophers that Carl cites in this context . It is clearly not true of some other pre-Kantian philoso- phers who deal with self-consciousness. ' References to the Critique of Pure.. (shrink)

The proper role, if any, for religion-based arguments is a live and sometimes heated issue within the field of bioethics. The issue attracts heat primarily because bioethical analyses influence the outcomes of controversial court cases and help shape legislation in sensitive biopolicy areas. A problem for religious bioethicists who seek to influence biopolicy is that there is now widespread academic and public acceptance, at least within liberal democracies, that the state should not base its policies on any particular religion’s metaphysical (...) claims or esoteric moral system. In response, bioethicists motivated by religious concerns have adopted two identifiable strategies. Sometimes they rely on slippery-slope arguments that, sometimes at least, have empirically testable premises. A more questionable response is the manipulation and misuse of secular-sounding moral language, such as references to “human dignity,” and the plights of groups of people labeled “vulnerable.”. (shrink)

This article provides an analysis of moral emotions from an attributional point of view, guided by the metaphors of man as a naïve scientist (Heider, 1958) and as a moral judge (Weiner, 2006). The theoretical analysis focuses on three concepts: (a) The distinction between the actor and the observer, (b) the functional quality of moral emotions, and (c) the perceived controllability of the causes of events. Moral emotions are identified (admiration, anger, awe, contempt, disgust, elevation, embarrassment, envy, gratitude, guilt, indignation, (...) jealousy, pity, pride, rage, regret, remorse, resentment, respect, schadenfreude, scorn, shame, and sympathy). A classification of these moral emotions is suggested and the empirical evidence briefly summarized. In discussing our results, we identify unresolved issues awaiting further analyses and research. (shrink)

The opinion of the American Medical Association (AMA) Council on Ethical and Judicial Affairs (CEJA) on the accommodation of conscientious objectors among medical doctors aims to balance fairly patients’ rights of access to care and accommodating doctors’ deeply held personal beliefs. Like similar documents, it fails. Patients will not find it persuasive, and neither should they. The lines drawn aim at a reasonable compromise between positions that are not amenable to compromise. They are also largely arbitrary. This article explains why (...) that is the case. The view that conscientious objection accommodation has no place in modern medicine is defended. (shrink)

Greek mythology developed ideas about the mythical birth of Athena from the head of Zeus in enigmatic allusions. Hephaestus performed the obstetrics. This cryptic mythologem, an imaginative structure of strange shape, contains a message from archaic Greece of unfathomable depth and furthermore has an extensive history of influence. After introductory remarks, the first part (A) of this paper contains a collection of the most important written sources that convey basic elements of the birth myth of Athena. Its allegorical interpretation was (...) initially undertaken by Stoic philosophers. Therefore, the second part (B) first reconstructs the integration and transformation of traditional myths into Stoic philosophy. Because the Stoics used basic aspects of their psychology for this purpose, investigations into Stoic psychology and localisation theory follow in the third part (C). Chrysippus used these constructions for an allegorical interpretation of the birth myth of Athena. Therefore, the fourth part (D) analyses his exegesis of this mythologem, about which extensive information is available, and subsequently Galen’s criticism of it. The famous philosophising physician moreover developed his own allegorical interpretation of the birth myth of Athena, drawing on his wealth of knowledge about the anatomy and physiology of the brain. The analysis of some significant statements on the ‘cerebral birth of Athena’ then follows in the fifth and last part (E). Documents from late antique literature, from Byzantine exegetes of Homer, comments from early medieval writers, the reflection of a modern brain anatomist and interpretations of this myth from the 19th century are discussed. An outlook with information on interdisciplinary brain research concludes the study. (shrink)

Viktor von Weizsäcker (1886-1957) wird oft als einer der Begründer der psychosomatischen Medizin im deutschsprachigen Raum angeführt. Doch ist mit dieser Zuschreibung sein Versuch einer grundlegenden Reform der Medizin nur unzureichend charakterisiert. Im Zentrum des vorliegenden Bandes stehen daher Studien zu seiner anthropologischen Medizin und Sozialmedizin, die nicht nur «psycho-somatisch» ausgerichtet, sondern auch erkenntnis- und gesellschaftskritisch gefaßt waren. Dabei wird sowohl die Aktualität der Gedanken von Weizsäckers als auch ihr Zeitbezug und ihre Zeitbedingtheit, gerade in den Jahren zwischen 1933 und (...) 1945, deutlich. (shrink)

This essay inquires into the semantics of the term “experience” in a selection of prose novels from the early modern period. Against the background of a complex history of discourses about experience, ultimately leading to a fully articulated concept of “empiricism” and “experiment”, the author traces the term’s usages in Hartlieb’s ‘Alexander’, in the novel ‘Fortunatus’ as well as in Wickram’s ‘Of Good and Bad Neighbours’. Furthermore, he elaborates those cultural topoi of experience that are based principally on an understanding (...) of “memory” and “adaptation”. As a result, the author is able to show, that all three texts place varying emphases on the topics of experience. (shrink)

In der sog. »aristotelischen Zeitaporie« (Physik IV) äußert sich Aristoteles zum Verhältnis von Zeit und Seele. Dieser Text gehört zu den umstrittensten Abschnitten seines Zeittraktates. Zur Interpretation rekonstruiert die vorgelegte Untersuchung die Entwicklungslinien der Analysen zur Zeitaporie von der Spätantike über die arabische Philosophie bis zur Frühphase der lateinischen Aristoteleskommentierung im 13. Jahrhundert. Der erste Abschnitt zeigt, wie die antike Physik-Kommentatoren diesen Text erklärten. Im Zentrum steht dabei die Auslegung des Alexander von Aphrodisias. Den der Spätantike diskutierten die Araber. Ein (...) zweite Abschnitt stellt daher die Analysen der arabischen Zeitphilosophie vor. Vermittelt durch lateinische Übersetzungen, beeinflussen arabische und jüdische Theoretiker die Zeitphilosophie des 13. Jahrhunderts. Die Geschichte des sukzessiven Vordringens der Konzeption des Averroes in die Auslegung der Zeitaporie im 13. Jahrhundert expliziert daher ein dritter Teil. Erst die Philosophen dieser Zeit konnten die These des Aristoteles zum Verhältnis von Zeit und Seele mit der Konzeption des Augustinus vergleichen. Sie haben das elfte Buch der Bekenntnisse neu entdeckt. (shrink)

"Der Vernunft kommt bei Eckhart fundamentalste Bedeutung zu. Sie bricht - so der Thüringer Meister - in den Grund. Ermöglicht wird sie durch das vernünftige Erkennen, das intelligere des Einen. In der Gottesgeburt wird der Mensch qualifiziert zu univokem Erkennen. Als Sohn Gottes wird der Mensch vernünftig zu weitem unbegrenztem Wissen geführt. Der Logos, das Wort ist substantiale und hermeneutische Grundlage vernünftigen Verstehens. Auch das Vergehen, die Sünde wird produktiv in dieses aufgenommen. Der Vernünftige ist der Demütige, Gelassene und Freie. (...) Das Höchste, was dem Menschen ontologisch und in seinem Wirken und Leben zuteil wird, ist das 'Draussen-wie-drinnen-Stehen'. Eckhart sagt: 'Lausche nun auf das Wunderbare! Welch wunderbares Stehen draußen wie drinnen, begreifen und umgriffen werden, schauen und das Geschaute selbst sein, es in sich haben und gehalten werden: das ist die Vollendung, wo der Geist voll Ruhe in der Einheit der lieben Ewigkeit bleibt'."--Page 4 of cover. (shrink)

Apoptosis is a physiological mechanism for the removal of unwanted or damaged cells. Apoptotic cells are rarely seen in living tissues, however, because of their rapid and efficient removal by phagocytosis. Phagocytotic cells such as macrophages or dendritic cells recognize apoptotic cells by specific changes of cell surface markers, which usually are not present on normal cells. One such event is the exposure of phosphatidylserine, which moves from the plasma membrane inner leaflet to the outer leaflet in preapoptotic cells. An (...) unresolved problem, however, was the nature of the phosphatidylserine receptor on the phagocytotic cells. In a recent issue of Nature, Fadok et al.(1) have reported the cloning of a phosphatidylserine receptor using an antibody raised against activated macrophages. Antibody treatment of these macrophages blocks this capacity to engulf. BioEssays 22:878–881, 2000. © 2000 John Wiley & Sons, Inc. (shrink)