Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients ( n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD (...) signal was evident in the left angular gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral gyrus (rPreG). Pain intensity (PI) analgesia was correlated ( r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN). (shrink)

Laws form counterfactually stable sets -- Natural necessity -- Three payoffs of my account -- A world of subjunctives.

Partiality is the special concern that we display for ourselves and other people with whom we stand in some special personal relationship. It is a central theme in moral philosophy, both ancient and modern. Questions about the justification of partiality arise in the context of enquiry into several moral topics, including the good life and the role in it of our personal commitments; the demands of impartial morality, equality, and other moral ideals; and commonsense ideas about supererogation. This paper provides (...) an overview of the debate on the ethics of partiality through the lens of the domains of permissible and required partiality. After outlining the conceptual space, I first discuss agent-centred moral options that concern permissions not to do what would be impartially optimal. I then focus on required partiality, which concerns associative duties that go beyond our general duties to others and require us to give special priority to people who are close to us. I discuss some notable features of associative duties and the two main objections that have been raised against them: the Voluntarist and the Distributive objections. I then turn to the justification of partiality, focusing on underivative approaches and reasons-based frameworks. I discuss the reductionism and non-reductionism debate: the question whether partiality is derivative or fundamental. I survey arguments for ‘the big three’, according to which partiality is justified by appeal to the special value of either projects, personal relationships, or individuals. I conclude by discussing four newly emerging areas in the debate: normative transitions of various personal relationships, relationships with AI, epistemic partiality, and negative partiality, which concerns the negative analogue of our positive personal relationships. (shrink)

Philosophy and Phenomenological Research, Volume 99, Issue 3, Page 714-719, November 2019.

Ceteris-paribus clauses are nothing to worry about; aceteris-paribus qualifier is not poisonously indeterminate in meaning. Ceteris-paribus laws teach us that a law need not be associated straightforwardly with a regularity in the manner demanded by regularity analyses of law and analyses of laws as relations among universals. This lesson enables us to understand the sense in which the laws of nature would have been no different under various counterfactual suppositions — a feature even of those laws that involve no ceteris-paribus (...) qualification and are actually associated with exceptionless regularities. Ceteris-paribus generalizations of an‘inexact science’ qualify as laws of that science in virtue of their distinctive relation to counterfactuals: they form a set that is stable for the purposes of that field. (Though an accident may possess tremendous resilience under counterfactual suppositions, the laws are sharply distinguished from the accidents in that the laws are collectively as resilient as they could logically possibly be.) The stability of an inexact science's laws may involve their remaining reliable even under certain counterfactual suppositions violating fundamental laws of physics. The ceteris-paribus laws of an inexact science may thus possess a kind of necessity lacking in the fundamental laws of physics. A nomological explanation supplied by an inexact science would then be irreducible to an explanation of the same phenomenon at the level of fundamental physics. Island biogeography is used to illustrate how a special science could be autonomous in this manner. (shrink)

Several foundational documents of bioethics mention the special obligation researchers have to vulnerable research participants. However, the treatment of vulnerability offered by these documents often relies on enumeration of vulnerable groups rather than an analysis of the features that make such groups vulnerable. Recent attempts in the scholarly literature to lend philosophical weight to the concept of vulnerability are offered by Luna and Hurst. Luna suggests that vulnerability is irreducibly contextual and that Institutional Review Boards (Research Ethics Committees) can only (...) identify vulnerable participants by carefully examining the details of the proposed research. Hurst, in contrast, defines the vulnerable as those especially at risk of incurring the wrongs to which all research ethics participants are exposed. We offer a more substantive conception of vulnerability than Luna but one that gives rise to a different rubric of responsibilities from Hurst's. While we understand vulnerability to be an ontological condition of human existence, in the context of research ethics, we take the vulnerable to be research subjects who are especially prone to harm or exploitation. Our analysis rests on developing a typology of sources of vulnerability and showing how distinct sources generate distinct obligations on the part of the researcher. Our account emphasizes that the researcher's first obligation is not to make the research participant even more vulnerable than they already are. To illustrate our framework, we consider two cases: that of a vulnerable population involved in international research and that of a domestic population of people with diminished capacity. (shrink)

Really statistical explanation is a hitherto neglected form of noncausal scientific explanation. Explanations in population biology that appeal to drift are RS explanations. An RS explanation supplies a kind of understanding that a causal explanation of the same result cannot supply. Roughly speaking, an RS explanation shows the result to be mere statistical fallout.

Very little has been done to find out what corporations have done to build ethical values into their organizations. In this report on a survey of 1984 Fortune 1000 industrial and service companies the Center for Business Ethics reveals some facts regarding codes of ethics, ethics committees, social audits, ethics training programs, boards of directors, and other areas where corporations might institutionalize ethics. Based on the survey, the Center for Business Ethics is convinced that corporations are beginning to take steps (...) to institutionalize ethics, while recognizing that in most cases more specific mechanisms and strategies need to be implemented to make their ethics efforts truly effective. (shrink)

A conservation law in physics can be either a constraint on the kinds of interaction there could be or a coincidence of the kinds of interactions there actually are. This is an important, unjustly neglected distinction. Only if a conservation law constrains the possible kinds of interaction can a derivation from it constitute a scientific explanation despite failing to describe the causal/mechanical details behind the result derived. This conception of the relation between “bottom-up” scientific explanations and one kind of “top-down” (...) scientific explanation is motivated by several examples from classical and modern physics. (shrink)

Several philosophers have suggested that some scientific explanations work not by virtue of describing aspects of the world’s causal history and relations, but rather by citing mathematical facts. This paper investigates what mathematical facts could be in order for them to figure in such “distinctively mathematical” scientific explanations. For “distinctively mathematical explanations” to be explanations by constraint, mathematical language cannot operate in science as representationalism or platonism describes. It can operate as Aristotelian realism describes. That is because Aristotelian realism enables (...) mathematics to apply to the physical world without a morphism’s mediation. (shrink)

This paper examines some recent attempts that use counterfactuals to understand the asymmetry of non-causal scientific explanations. These attempts recognize that even when there is explanatory asymmetry, there may be symmetry in counterfactual dependence. Therefore, something more than mere counterfactual dependence is needed to account for explanatory asymmetry. Whether that further ingredient, even if applicable to causal explanation, can fit non-causal explanation is the challenge that explanatory asymmetry poses for counterfactual accounts of non-causal explanation. This paper argues that several recent (...) accounts Explanation beyond causation: philosophical perspectives on non-causal explanations, Oxford University Press, Oxford, pp 117–140, 2018; Jansson and Saatsi in Br J Philos Sci, forthcoming; Jansson in J Philos 112:7–599, 2015; Saatsi and Pexton in Philos Sci 80: 613–624, 2013; French and Saatsi, in: Reutlinger and Saatsi Explanation beyond causation: philosophical perspectives on non-causal explanations, Oxford University Press, Oxford, pp 185–205, 2018) fail to meet this challenge. The paper then sketches a more positive proposal for dealing with explanatory asymmetry in non-causal explanations. (shrink)

This paper argues that in at least some cases, one proof of a given theorem is deeper than another by virtue of supplying a deeper explanation of the theorem — that is, a deeper account of why the theorem holds. There are cases of scientific depth that also involve a common abstract structure explaining a similarity between two otherwise unrelated phenomena, making their similarity no coincidence and purchasing depth by answering why questions that separate, dissimilar explanations of the two phenomena (...) cannot correctly answer. The connections between explanation, depth, unification, power, and coincidence in mathematics and science are compared. (shrink)

I here settle a recent dispute between two rival theories in distributive ethics: Restricted Prioritarianism and the Competing Claims View. Both views mandate that the distribution of benefits and burdens between individuals should be justifiable to each affected party in a way that depends on the strength of each individual’s separately assessed claim to receive a benefit. However, they disagree about what elements constitute the strength of those individuals’ claims. According to restricted prioritarianism, the strength of a claim is determined (...) in ‘prioritarian’ fashion by both what she stands to gain and her absolute level of well-being, while, according to the competing claims view, the strength of a claim is also partly determined by her level of well-being relative to others with conflicting interests. I argue that, suitably modified, the competing claims view is more plausible than restricted prioritarianism. (shrink)

Recently, biologists and computer scientists who advocate the "strong thesis of artificial life" have argued that the distinction between life and nonlife is important and that certain computer software entities could be alive in the same sense as biological entities. These arguments have been challenged by Sober (1991). I address some of the questions about the rational reconstruction of biology that are suggested by these arguments: What is the relation between life and the "signs of life"? What work (if any) (...) might the concept of "life" (over and above the "signs of life") perform in biology? What turns on scientific disputes over the utility of this concept? To defend my answers to these questions, I compare "life" to certain other concepts used in science, and I examine historical episodes in which an entity's vitality was invoked to explain certain phenomena. I try to understand how these explanations could be illuminating even though they are not accompanied by any reductive definition of "life.". (shrink)

In a notable article entitled “What is the Theory of Relativity?” written at the request of The Times and published in its November 28, 1919 edition, Albert Einstein famously distinguished “theories of principle” from “constructive theories.” Einstein placed relativity theory among the principle theories. His distinction has recently received increased attention, especially as it relates to scientific explanation. In particular, there has been considerable discussion of how to explain why there obtain the Lorentz transformations as well as of how to (...) account for the Lorentz covariance of the dynamical laws. Some .. (shrink)

Why should science be so interested in discovering whether p is a law over and above whether p is true? The answer may involve the laws' relation to counterfactuals: p is a law iff p would still have obtained under any counterfactual supposition that is consistent with the laws. But unless we already understand why science is especially concerned with the laws, we cannot explain why science is especially interested in what would have happened under those counterfactual suppositions consistent with (...) the laws. It is argued that the laws form the only non-trivially "stable" set, where "stability" is invariance under a certain range of counterfactual suppositions not itself defined by reference to the laws. It is then explained why science should be so interested in identifying a non-trivially "stable" set: because of stability's relation to the best set of "inductive strategies". (shrink)

This paper concerns the relation between a proof’s beauty and its explanatory power – that is, its capacity to go beyond proving a given theorem to explaining why that theorem holds. Explanatory power and beauty are among the many virtues that mathematicians value and seek in various proofs, and it is important to come to a better understanding of the relations among these virtues. Mathematical practice has long recognized that certain proofs but not others have explanatory power, and this paper (...) offers an account of what makes a proof explanatory. This account is motivated by a wide range of examples drawn from mathematical practice, and the account proposed here is compared to other accounts in the literature. The concept of a proof that explains is closely intertwined with other important concepts, such as a brute force proof, a mathematical coincidence, unification in mathematics, and natural properties. Ultimately, this paper concludes that the features of a proof that would contribute to its explanatory power would also contribute to its beauty, but that these two virtues are not the same; a beautiful proof need not be explanatory. (shrink)

For theologians, to conceive of God in terms of light has some undeniable advantages, allowing a middle-of-the road position between the two extremes of thinking about God in terms of a purely disembodied, unfathomable, unsensible being, and of crediting Him with a body, possibly even a human body. This paper first reviews the reasons why God, in early medieval Islam, was never fully theorized in terms of light. It then proceeds to discuss light-related narratives in two major, late-medieval compilations of (...) hadiths about the afterlife, by al-Suyuti and al-Majlisi, suggesting that eschatology was the area in which God’s light continued to shine in Islam, and the backdoor through which a theology of light, in the thought of al-Suhrawardi and his followers, made a triumphant re-entry into Islamic thought. (shrink)

I offer an argument regarding chances that appears to yield a dilemma: either the chances at time t must be determined by the natural laws and the history through t of instantiations of categorical properties, or the function ch(•) assigning chances need not satisfy the axioms of probability. The dilemma's first horn might seem like a remnant of determinism. On the other hand, this horn might be inspired by our best scientific theories. In addition, it is entailed by the familiar (...) view that facts about chances at t are ontologically reducible to facts about the laws and the categorical history through t. However, that laws are ontologically prior to chances stands in some tension with the view that chances are governed by laws just as categorical-property instantiations are. The dilemma's second horn entails that if chances are in fact probabilities, then this is a matter of natural law rather than logical or conceptual necessity. I conclude with a suggestion for going between the horns of the dilemma. This suggestion involves a generalization of the notion that chances evolve by conditionalization. Introduction "Chances evolve by conditionalization" How might the lawful magnitude principle be defended? A historical interlude What if chances failed to be determined by the laws and categorical facts? (shrink)

With the rise and public accessibility of AI-enabled decision-support systems, individuals outsource increasingly more of their decisions, even those that carry ethical dimensions. Considering this trend, scholars have highlighted that uncritical deference to these systems would be problematic and consequently called for investigations of the impact of pertinent technology on humans’ ethical decision-making. To this end, this article conducts a systematic review of existing scholarship and derives an integrated framework that demonstrates how intelligent decision-support systems (IDSSs) shape humans’ ethical decision-making. (...) In particular, we identify resulting consequences on an individual level (i.e., deliberation enhancement, motivation enhancement, autonomy enhancement and action enhancement) and on a societal level (i.e., moral deskilling, restricted moral progress and moral responsibility gaps). We carve out two distinct methods/operation types (i.e., processoriented and outcome-oriented navigation) that decision-support systems can deploy and postulate that these determine to what extent the previously stated consequences materialize. Overall, this study holds important theoretical and practical implications by establishing clarity in the conceptions, underlying mechanisms and (directions of) influences that can be expected when using particular IDSSs for ethical decisions. (shrink)

Suppose that unobtanium-346 is a rare radioactive isotope. Consider: (1) Every Un346 atom, at its creation, decays within 7 microseconds (µs). (50%) Every Un346 atom, at its creation, has a 50% chance of decaying within 7µs. (1) and (50%) can be true together, but (1) and (50%) cannot together be laws of nature. Indeed, (50%)'s mere (non-vacuous) truth logically precludes (1)'s lawhood. A satisfactory analysis of chance and lawhood should nicely account for this relation. I shall argue first that David (...) Lewis's Humean picture accounts for this relation only by inserting this relation ‘by hand’. Next, I shall argue that this relation between law and chance also threatens a radically non-Humean picture of laws and chances. Finally, I shall offer an account of natural law that nicely explains the relation between chancy facts and deterministic laws. This explanation is not ad hoc because it derives the relation from the very same features of lawhood that account for the laws' special relation to counterfactuals and explain how the laws (unlike the accidents) possess a variety of necessity. The reason that a chancy fact such as (50%) keeps (1) from being a law, without keeping (1) from being true, is ultimately that a chancy fact constrains the subjunctive facts and (1)'s lawhood, unlike (1)'s truth, depends upon the subjunctive facts. (shrink)

In “Tense and Reality”, Kit Fine () proposed a novel way to think about realism about tense in the metaphysics of time. In particular, he explored two non-standard forms of realism about tense, arguing that they are to be preferred over standard forms of realism. In the process of defending his own preferred view, fragmentalism, he proposed a fragmentalist interpretation of the special theory of relativity, which will be our focus in this paper. After presenting Fine's position, we will raise (...) a problem for his fragmentalist interpretation of STR. We will argue that Fine's view is in tension with the proper explanation of why various facts obtain. We will then consider whether similar considerations also speak against fragmentalism in domains other than STR, notably fragmentalism about tense. (shrink)

It has frequently been argued recently that Jeffrey Conditionalization (JC) does not permit undermining. For JC to be inapplicable in cases where the evidence could be undermined would severely compromise JC’s range. However, this paper contends that the argument fails to show that JC cannot accommodate undermining. This response turns on using the proper partition to capture the direct impact of our evidence in redistributing our credences.

AI-supported methods for identifying and combating disinformation are progressing in their development and application. However, these methods face a litany of epistemic and ethical challenges. These include (1) robustly defining disinformation, (2) reliably classifying data according to this definition, and (3) navigating ethical risks in the deployment of countermeasures, which involve a mixture of harms and benefits. This paper seeks to expose and offer preliminary analysis of these challenges.

This paper has been published in 2015 in Environment and Planning D, 33 : p. 1080–1097. It is freely available from Copenhagen Business School. We thank the authors for the permission to reproduce it here.: This paper explores the relationship between bodily rhythms and market rhythms in two distinctly different financial market configurations, namely the open-outcry pit and present-day high-frequency trading. Drawing on Henri - Management et Business – Nouvel article.

Solipsism is an extreme position. Ludwig Wittgenstein addressed this position several times over more than 20 years. Wittgenstein first became familiar with solipsism under the title of “theoretical egoism” when reading Schopenhauer at the tender age of 16. Elizabeth Anscombe related a personal conversation in which Wittgenstein said that Schopenhauer's theory of the world “as idea” struck him as fundamentally right, if in need of a few clarifications and adjustments, but that he opposed the theory of the world as will. (...) Wittgenstein's first philosophy was that of Schopenhauer and he was only liberated from it by Frege's conceptual realism. According to Schopenhauer, an “organic” philosophy needs an organic exposition. An organic philosophy stands in contrast to systematic philosophy, which argues sequentially “in the form of a chain” of propositions starting from one fundamental principle. Wittgenstein's overarching aim in the Tractatus is to delimit sense by expounding the limits for the expression of thoughts in language. (shrink)

CRISPR is currently viewed as the central tool for future gene therapy. Yet, many prominent scientists and bioethicists have expressed ethical concerns around CRISPR gene therapy. This paper provides a critical review of concerns about CRISPR gene therapy as expressed in the mainstream academic literature, paired with replies also generally found in that literature. The expressed concerns can be categorised into three types depending on whether they stress risk/benefit ratio, autonomy and informed consent, or concerns related to various aspects of (...) justice. In the reviewed literature, we found no intrinsic objections to CRISPR gene therapy, even though many such objections were present in discussions of gene editing in the 1990s. The paper then proposes a brief outline for a practically applicable moral framework for public decision-making about CRISPR gene therapy and suggests how such a framework might be supported. We also suggest that this framework should govern public engagement about CRISPR gene therapy in order to reduce the risk that we make decisions about CRISPR gene therapy based on misperceptions, inflated views of risk, or unreasonable moral or religious views. (shrink)

We argue that if there are laws of nature, then there must also be accidents. If the “laws” in a world suffice to determine the world’s entire history, then these “laws” cannot play various central roles characteristic of laws, and thus (we conclude) they are not laws at all. Many proposed accounts of lawhood (primitivist accounts, universals accounts, the Best System Account, the Package Deal Account, essentialist accounts) inappropriately permit worlds with laws but no accidents. We identify two otherwise dissimilar (...) accounts that correctly (on our view) deem such worlds impossible; one is Humean and the other is non-Humean. (shrink)

A long lasting debate in the field of implicit learning is whether participants can learn without acquiring conscious knowledge. One crucial problem is that no clear criterion exists allowing to identify participants who possess explicit knowledge. Here, we propose a method to diagnose during a serial reaction time task those participants who acquire conscious knowledge. We first validated this method by using Stroop-like material during training. Then we assessed participants’ knowledge with the Inclusion/Exclusion task and the wagering task . Both (...) experiments confirmed that for participants diagnosed as having acquired conscious knowledge about the underlying sequence the Stroop congruency effect disappeared, whereas for participants not diagnosed as possessing conscious knowledge it only slightly decreased. In addition, both experiments revealed that only participants diagnosed as conscious were able to strategically use their acquired knowledge. Thus, our method allows to reliably distinguish between participants with and without conscious knowledge. (shrink)

Does smoke cause fire or does fire cause smoke? James Woodward’s “Flagpoles anyone? Causal and explanatory asymmetries” argues that various statistical independence relations not only help us to uncover the directions of causal and explanatory relations in our world, but also are the worldly basis of causal and explanatory directions. We raise questions about Woodward’s envisioned epistemology, but our primary focus is on his metaphysics. We argue that any alleged connection between statistical (in)dependence and causal/explanatory direction is contingent, at best. (...) The directions of causal/explanatory relations in our world seem not to depend on the statistical (in)dependence relations in our world (conceived of either as frequency patterns or as relations among chances). Thus, we doubt that statistical (in)dependence relations are the worldly basis of causal and explanatory directions. (shrink)

A educação e as comemorações cívicas foram temas bastante discutidos em âmbito nacional. Tais temas não deixaram de fazer parte das páginas do jornal O Rebate que fazia oposição ao Partido Republicano Rio-Grandense (PRR). O presente trabalho dedica-se à análise das notícias sobre festas cívicas e educação cívica, publicadas no referido jornal, em 1914 e 1915, primeiros anos de funcionamento desse órgão de imprensa. Embora tal periódico constasse como "orgam independente", a filiação partidária de seu editor norteou as críticas e (...) os temas tratados nas páginas dessa publicação. Além disso, foram utilizados os Relatórios Intendenciais de 1914 e 1915, para que fosse realizada uma comparação entre os discursos antagônicos presentes na vida política de Pelotas, tendo em vista que o então intendente, Cypriano Corrêa Barcellos, estava vinculado ao PRR. Para a realização deste trabalho, fez uma revisão bibliográfica do tema educação cívica no Brasil, além de buscar subsídios para a análise de impressos. (shrink)

This paper analyzes the historical and cultural genealogy of the presumed separation between ethics and economic theory, taking publicly supported care for children of working mothers (or parents) as a case that illuminates problems for thinking about gender justice that arise because of these disciplinary boundaries and the particular concept of “the human individual” that is implicit in them. Care for children of working mothers is an issue that has been important in the West since the inception of “second wave” (...) feminism. However, I argue that the global expectation that women are responsible for care of small children, coupled with the reality that small children really must have caregivers, makes this issue pertinent to women everywhere, and it has lately been recognized as an issue for development and global justice. Predominant political philosophies and neoclassical economics have a common philosophical root in abstract individualist method. I argue that this has made possible a claim of intellectual respectability for neo-liberal politics that resists feminist and postcolonial critique, even though these critiques show its inability to deal with matters, such as the need for child care, that have moral issues inextricably involved in them. The economy of rationalindividual self-interest has so far only generated child care with a very large component of exploitation of caregivers. (shrink)