Specificities of enzymes involved in plant specialized metabolism, including flavonoid biosynthesis, are generally promiscuous. This enzyme promiscuity has served as an evolutionary basis for new enzyme functions and metabolic pathways in land plants adapting to environmental challenges. This phenomenon may lead, however, to inefficiency in specialized metabolism and adversely affect metabolite‐mediated plant survival. How plants manage enzyme promiscuity for efficient specialized metabolism is, thus, an open question. Recent studies of flavonoid biosynthesis addressing this issue have revealed a conserved strategy, namely, (...) a homolog of chalcone isomerase with no catalytic activity binds to chalcone synthase, a key flavonoid pathway enzyme, to narrow (or rectify) the enzyme's highly promiscuous product specificity. Reducing promiscuity via specific protein–protein interactions among metabolic enzymes and proteins may be a solution adopted by land plants to achieve efficient operation of specialized metabolism, while the intrinsic promiscuity of enzymes has likely been retained incidentally. (shrink)

This paper studies a sender-receiver game in which both players want the receiver to choose the state-optimal action. Before observing the state, the sender observes a “contextual signal,” a payoff-irrelevant signal that correlates with states and is imperfectly shared with the receiver. Once the sender observes the state, the sender sends a message to the receiver, incurring a small messaging cost. It is shown that there is no miscommunication in any efficient equilibrium if the messaging cost is uniform or contextual (...) information is poorly shared between players. However, if the messaging costs are different between some messages, and contextual information can affect the probability ranking of states and is shared reasonably well, any efficient equilibrium that favors the sender exhibits miscommunication. Furthermore, the messages that cause miscommunication can be coarse or ambiguous, depending on how well players share contextual information. (shrink)

While directors’ task boundaries are usually ambiguous, some of their activities or behaviors clearly constitute their formal duties, whereas others are usually perceived as organizational citizenship behavior. Applying identity theory, we present a theoretical model that demonstrates one of the key drivers for directors to engage in OCB with a focus on their role identity. We argue that an individual director’s role identity is one of the key factors that motivate directors to engage in OCB. Furthermore, we propose that two (...) board-level contingencies, board capital, and informal board hierarchy order, can moderate the effect of directors’ role-identity salience on their OCB. That is, low levels of board capital and directors’ higher positions in a board’s informal hierarchy enhance directors’ motivation to engage in OCB. (shrink)

This paper introduces a common-interest communication game that generates pragmatics, where meaning emerges from the use of a preexisting language under equilibrium selection driven solely by efficiency. A key feature is that the sender describes the current state to the receiver by combining preexisting statements. This approach allows us to formalize two communication frictions: (i) longer descriptions incur higher costs, and (ii) with some probability, the receiver interprets only the conventional meaning. The absence of one friction leads to some efficient (...) equilibria exhibiting pragmatics that disregards conventional meaning. However, when communication costs are sufficiently small, given the other friction, any efficient equilibrium exhibits natural pragmatics that refines conventional meaning, reflecting the context provided by the probability distribution of states. The resulting equilibrium pragmatics aligns with major linguistic theories, including Grice’s cooperative principle (1975) and Sperber and Wilson’s relevance theory (1986). (shrink)

Resumo: O presente estudo procura construir novas hipóteses interpretativas sobre a gênese do poder civil em Thomas Hobbes, a partir do estudo da passagem clássica do estado de natureza para o estado civil. Consideramos que tal passagem, para além das interpretações canônicas, é um topos, encontrado na tradição retórica, especialmente em Cícero, em seu De inventione. Neste contexto, o discurso eloquente aparece como elemento originário e fundamental do Estado civil. Tal apropriação por parte de Hobbes emerge dentro de uma perspectiva (...) que trata a arte retórica como fonte de conhecimento, sobrepondo a questão do ornato da linguagem, de modo a compor um importante elemento dentro de sua concepção de poder civil. (shrink)

The target article about the origin and evolution of the isocortex triggers questions about unresolved issues that still need to be dealt with, including: (1) the evolutionary scenario of the origin of the lateral isocortex, (2) the expansion of the dorsal pallium in nonmammals, and (3) the heterogeneity of the anterior dorsal ventricular ridge.

Husserl’s phenomenology arose in a time of crisis for the sciences; today, we confront a crisis of interculturality. In this paper, I thematize the architectural and agricultural aspect of phenomenological thinking with regard to the notion of »culture«. Here, the ego is not so much a master who bestows sense on the world, but a Gesinde, who follows the direction of »sense« and through whom sense constitutes itself. Husserl’s method of Besinnung with regard to European history is based upon this (...) idea. This way of thinking is rooted in the European notion of »agriculture”«, where sense is built up slowly and we have time to accommodate ourselves to change. Today, however, we live in a situation of high-speed interculturality where egos of mutually foreign cultures encounter each other at such high speed that the safety mechanisms of agriculture no longer function. This is our present state of crisis. (shrink)

Japan has absorbed many western ideas since the late nineteenth century, but Japanese philosophers have often been reluctant to accept the western idea of the “I” in its entirety. The I transgresses to the Other more easily than western philosophies think and imports what belongs to the Other as his own. How is this possible? Husserl attempted to explain the constitution of the Other by the intentionality that goes from the I to the Other, mediated by the body. However, Husserl (...) later discovered that the constitution of both the I and the Other is more of a two-way movement. This double-movement is essential for all constitutions and departs from a deep (primal) dimension that is not yet egological. Even in the self-reflection of the I, a similar double-movement between the primal and egological dimensions can be seen. The I is supported, but at the same time threatened, by this movement. (shrink)

Husserl attempted to found logics and language on intuition, and particularly perception. The relationship between logical language and intuition is therefore one of the fundamental themes of his phenomenology. Husserl regarded the two as sharing an isomorphic structure, and this article shows that this structure can be characterized as “mediality.” That is, the “meaning” of language appears by mediation of sound or script, while the “I” as person appears by mediation of the body. I will show furthermore that intuitions themselves (...) appear through the mediation of language, and interpret this idea of mediality in terms of the Japanese language. Guided by Husserl’s notion of Sprachleib, I will also attempt an analysis of the “bodily” function of Chinese script and onomatopeia as aspects of Sprachleib and show how the Sprachleib functions as a “cultural living body” that makes community possible. (shrink)

When an agent’s motivation is sensitive to how his supervisor thinks about the agent’s competence, the supervisor has to take into account both informational and expressive contents of her message to the agent. This paper shows that the supervisor can credibly express her trust in the agent’s ability only by being un- clear about what to do. Suggesting what to do, i.e., “directives,” could reveal the supervisor’s “distrust” and reduce the agent’s equilibrium effort level even though it provides useful information (...) about the decision environment. There is also an equilibrium in which directives are neutral in expressive content. However, it is shown that neologism proofness favors equilibria in which directives are double- edged swords. (shrink)

Does a penny per month constitute a Basic Income? Were that penny to be paid individually, universally, and unconditionally, the answer would be ‘yes’, following the definition of Basic Income given by some of its leading advocates, be it organisations like the Basic Income Earth Network or prominent scholars such as Philippe Van Parijs. Some might be puzzled as to how this could be ‘a capitalist road to communism’, or give us ‘freedom as the power to say no’, both of (...) which have been advocated by prominent researchers. The purpose of this paper is not to argue for or against their definition, but rather to situate it historiographically, enabling fruitful discussion. The paper will show how there was a widely shared assumption in the 1970s and 80s, at the early stages of both academic articulations and public discussion, that Basic Income comes with some notion of a threshold or level to be taken as a minimum or as adequate. The paper goes on to outline three issues that arise once the concept of a threshold is dropped from the definition. Examined in addition are five justifications for doing so. Much like any other idea, the concept of Basic Income is a social construct. By situating it here within a historical perspective, we wish to facilitate academic discussion regarding both the achievements and erasures that have occurred as a consequence of the concept’s academic refinement—refinement that is in itself majorly indebted to BIEN and Van Parijs. (shrink)

Since sending explicit messages can be costly, people often utilize “what is not said,” i.e., informative silence, to economize communication. This paper studies the efficient communication rule, which is fully informative while minimizing the use of explicit messages, in cooperative environments. It is shown that when the notion of context is defined as the finest mutually self-evident event that contains the current state, the efficient use of informative silence exhibits the defining property of indexicals in natural languages. While the efficient (...) use of silence could be complex, it is also found that the efficient use of silence can be as “simple” as the use of indexicals in natural languages if and only if the information structure satisfies some centrality and dominance properties. (shrink)

This paper will deal with the relationship between 'life' (Leben) and the 'life-world' (Lebenswelt) 1 as we find these concepts in the writings of Husserl's last years. The emphasis will be upon elucidating this relation- ship from the transcendental point of view. It is well known that Husserl initially introduced the concept of the life-world into his philosophy in connection with the problem of founding the sciences: accordingly, most studies up to date have dealt with the concept within this context (...) - that is, as part of the program for founding the sciences. However, it is important to remember that the life-world is also, for Husserl, a 'way to the transcendental reduction', and as such, can be ultimately clari- fied only by following this way to its end, and by comprehending it in its relationship to transcendental subjectivity. In his later years, Husserl came to think of the 'way of being' (Seinsweise) of transcendental sub- jectivity as 'world-experiencing-life' (welterfahrendes Leben). Thus it is my view that the problem of the 'life-world' is intimately related to that of 'life', and must necessarily be treated in the context of that rela- tionship. (shrink)

Many studies have reported neural correlates of visual awareness across several brain regions, including the sensory, parietal, and frontal areas. In most of these studies, participants were instructed to explicitly report their perceptual experience through a button press or verbal report. It is conceivable, however, that explicit reporting itself may trigger specific neural responses that can confound the direct examination of the neural correlates of visual awareness. This suggests the need to assess visual awareness without explicit reporting. One way to (...) achieve this is to develop a technique to predict the visual awareness of participants based on their peripheral responses. Here, we used eye movements and pupil sizes to decode trial-by-trial changes in the awareness of a stimulus whose visibility was deteriorated due to adaptation-induced blindness. In the experiment, participants judged whether they perceived a target stimulus and rated the confidence they had in their perceptual judgment, while their eye movements and pupil sizes were recorded. We found that not only perceptual decision but also perceptual confidence can be separately decoded from the eye movement and pupil size. We discuss the potential of this technique with regard to assessing visual awareness in future neuroimaging experiments. (shrink)

Principles of Brain Evolution (Striedter 2005) places little emphasis on natural selection. However, one cannot fully appreciate the diversity of brains across species, nor the evolutionary processes driving such diversity, without an understanding of the effects of natural selection. Had Striedter included more extensive discussions about natural selection, his text would have been more balanced and comprehensive.

Trata-se de uma resenha da tradução de Celi Hirata das Questões sobre a Liberdade, a Necessidade e o Acaso de Thomas Hobbes.

A decision maker (DM) selects a project from a set of alternatives with uncertain productivity. After the choice, she observes a signal about productivity and decides how much effort to put in. This paper analyzes the optimal decision problem of the DM who rationally filters information to deal with her post-decision cognitive dissonance. It is shown that the optimal effort level for a project can be affected by unchosen projects in her choice set, and the nature of the choice set-dependence (...) is determined by the signal structure. Some comparative statics of choice set-dependence is also provided. Finally, based on the results, the optimal choice set design is also explored. This paper offers a simple framework to explain the experimental finding in psychology that people’s effort level for a project can be enhanced when the project is chosen by themselves rather than by others. (shrink)

Spatial ability plays important roles in academic learning and everyday activities. A type of spatial thinking that is of particular significance to people's daily lives is cognitive mapping, that is, the process of acquiring, representing, and using knowledge about spatial environments. However, the skill of cognitive mapping shows large individual differences, and the task of spatial orientation and navigation poses great difficulty for some people. In this article, I look at the motivation and findings in the research into spatial knowledge (...) acquisition from an individual differences perspective. I also discuss major implications of the existence of large individual differences, particularly the possibility of improving cognitive mapping by training and adjusting navigation assistance to the wide variations in spatial aptitudes and preferences among people. (shrink)

Consciousness – Bewußtsein – was one of the key concepts of Husserl’s phenomenology. In contrast to this, Heidegger – regarded as Husserl’s most outstanding pupil – placed Dasein at the center of his own phenomenology. This change in key concepts may be seen as an upheaval in the phenomenology that purports to study the “things themselves”: as a shift of focus from the activity of a Bewußtsein that constitutes the Being of objects, to the passivity of a Dasein that receives (...) the donation of Being. But there is another aspect of Dasein that lies in the concept of “Da” (disclosedness), and it implies another possibility for the development of phenomenology that Heidegger did not fully develop. Kitaro Nishida, the Japanese philosopher who introduced phenomenology to Japan during the first half of the 20th century, developed this concept in his own way by analyzing the structure of disclosedness in terms of self-consciousness. (shrink)

O presente estudo argumenta que, para Hobbes, a retórica constituiu-se como um importante aparato linguístico e conceitual disponível em seu tempo, sobretudo para a descrição dos fenômenos físicos na ciência experimental nascente no contexto do século XVII inglês. Considerando que os parâmetros epistêmicos na descrição desta ciência estavam por se desenvolver, Hobbes buscou soluções nas doutrinas das artes do bem falar, a começar em sua antropologia. A noção de conato em Hobbes indica o peso da tradição retórica clássica em sua (...) filosofia, com destaque para Aristóteles, os estoicos e Quintiliano. Veremos como a retórica, articulada à física e à ética, constituiu um relevante paradigma de expressão e de investigação de Thomas Hobbes sobre o conato e vai além do ornamento do texto em seu estudo sobre os corpos. (shrink)