This critical response to Dominic Smith’s ‘Taking Exception: Philosophy of Technology as a Multidimensional Problem Space’ begins by outlining the key contributions of his essay, namely his insightful approach to the transcendental, on the one hand, and his introduction of the topological problem space as an image for thought, on the other. The response then suggests ways of furthering this approach by addressing potential reservations about determinism. The response concludes by suggesting a way out of these questions of determinism by (...) thinking the transcendental in concert with the agonistic. (shrink)

Despite the fact that information systems ontologies [ISOs] support the mutual understanding between human beings and software applications, human beings and software applications do not understand ISOs' contents in the same way. The same applies to ontological integration. This paper attempts to account for such discrepancies by emphasizing that while human being can have access to entities represented in ISOs, software applications cannot.

When I take off my glasses, the world looks blurred. When I put them back on, it looks sharpedged. I do not think that the world really was blurred; I know that what changed was my relation to the distant physical objects ahead, not those objects themselves. I am more inclined to believe that the world really is and was sharp-edged. Is that belief any more reasonable than the belief that the world really is and was blurred? I see more (...) accurately with my glasses on than off, so visual appearances when they are on have some cognitive priority over visual appearances when they are off. If I must choose which kind of visual appearance to take at face value, I will choose the sharp-edged look. But what should I think when I see a mist, which looks very blurred however well I am seeing? Indeed, why choose to take any of the looks at face value? Why not regard all the choices as illegitimate projections of ways of seeing the world onto the world itself? (shrink)

§0. A familiar if obscure idea: an indicative conditional presents its consequent as holding in the actual world on the supposition that its antecedent so holds, whereas a subjunctive conditional merely presents its consequent as holding in a world, typically counterfactual, in which its antecedent holds. Consider this pair.

Some commentators have criticized bioethics as failing to engage religion both as a matter of theory and practice. Bioethics should work toward understanding the influence of religion as it represents people's beliefs and practices, but bioethics should nevertheless observe limits in regard to religion as it does its normative work. Irreligious skepticism toward religious views about health, healthcare practices and institutions, and responses to biomedical innovations can yield important benefits to the field. Irreligious skepticism makes it possible to raise questions (...) that otherwise go unasked and to protect against the overreach of religion. In this sense, bioethics needs a vigorous irreligious outlook every bit as much as it needs descriptive understandings of religion. (shrink)

Originally published in 1988, this landmark study develops its own positive account of the nature and foundations of moral judgement, while at the same time serving as a guide to the range of views on the matter which have been given in modern western philosophy. The book addresses itself to two main questions: Can moral judgements be true or false in that fundamental sense in which a true proposition is one which describes things as they really are? Are rational methods (...) available in ethics which can be expected to produce convergence on shared moral views on the part of those who use them intelligently? (shrink)

The paper outlines and explores a possible strategy for defending both the action/omission distinction (AOD) and the principle of double effect (PDE). The strategy is to argue that there are degrees of actionhood, and that we are in general less responsible for what has a lower degree of actionhood, because of that lower degree. Moreover, what we omit generally has a lower degree of actionhood than what we actively do, and what we do under known-but-not-intended descriptions generally has a lower (...) degree of actionhood than what we do under known-and-intended descriptions. Therefore, we are in general less responsible for what we omit than for what we do—which is just what AOD says. And we are in general less responsible for what we do under known-but-not-intended descriptions than for what we do under known-and-intended descriptions—which is just what PDE says. (shrink)

Essential Philosophy of Psychiatry is a concise introduction to the growing field of philosophy of psychiatry. Divided into three main aspects of psychiatric clinical judgement, values, meanings and facts, it examines the key debates about mental health care, and the philosophical ideas and tools needed to assess those debates, in six chapters. In addition to outlining the state of play, Essential Philosophy of Psychiatry presents a coherent and unified approach across the different debates, characterized by a rejection of reductionism and (...) an emphasis on the ineliminability of uncodified skilled judgement. The first part, Values, outlines the debate about whether diagnosis of mental illness is essentially value-laden and argues that the prospects for reducing illness or disease to plainly factual matters are poor. It also explains the important role of skilled contextual judgement, rather than a principles-based deduction, in ethical judgement. The second part, Meanings, examines the central role of understanding and a shared first person perspective, both against attempts to reduce meaning to basic information-processing mechanisms and to explain away the difficulties of understanding psychopathology in recent models of delusion. The third part, Facts, shows the importance of uncodified clinical judgements, both in assessing the validity of psychiatric taxonomy and in the application of Evidence Based Medicine. Despite advances in the codifaction of practice and operationalism of diagnosis, an element of judgement remains in the assessment both of what, at one level, is good evidence for diagnosis and treatment and what, at a higher level, is good evidence for the validity of classification overall. (shrink)

Contextualism is relativism tamed. Relativism about truth is usually motivated by the idea of no-fault disagreement. Imagine two parties: one (she) says ‘P’; the other (he) says ‘Not P’.1 Apparently, if P then ‘P’ is true and ‘Not P’ false, so she is right and he is wrong; if not P then ‘P’ is false and ‘Not P’ true, so he is right and she is wrong. In both cases, there is an asymmetry between the two parties. Since P or (...) not P (by the law of excluded middle), there is indeed an asymmetry between them, one way or the other. Yet the two parties may strike a neutral observer as on a par, equally intelligent, informed, perceptive and alert. Relativists about truth strive to dissolve the unpleasant asymmetry: ‘”P” is true for her; “Not P” is true for him’. Trouble starts when we ask what the relativists mean by ‘for’ in the construction ‘true for X’. If to call something true ‘for’ X is just to say that X believes that it is true, then the attempted dissolution amounts to this: ‘She believes that “P” is true; he believes that “Not P” is true’. But that is to add no more than that both parties believe that they are right; it does nothing to undermine the argument for an asymmetry between them. Relativists had better mean something else by ‘true for X’. When asked to explain what else they mean, wild relativists bluster incoherently. Contextualists, by contrast, have a clear answer. A sentence is true for X if and only if it is true as uttered by X, true relative to a context in which X is the speaker. Such relativism is tame because the relativity to context in the truth-value of a sentence allows for absoluteness in the truth-value of what the sentence is used to say in a given context. When she says ‘P’, she speaks truly: not just truly for her, but absolutely truly. When he says ‘Not P’, he too speaks truly: not just truly for him, but absolutely truly. The argument for asymmetry 1 assumes that, when she says ‘P’, she speaks truly if and only if P, and when he says ‘Not P’, he speaks truly if and only if not P.. (shrink)

What role does religious transcendence play in liberal democracies? In Jürgen Habermas’s early political theory of the bourgeois public sphere, religion was downplayed if not dismissed completely. In the past several years however, he has developed a greater interest in religion. Habermas seems to like the positive solidarity-forming effects religion can have on communities that mediate in a public sphere between private individuals and state authority. However, in light of continuing terrorist activity, he is deeply critical of any sort of (...) other worldly transcendence that is too open to violent cooption. Nonetheless, Habermas relates his renewal of a critically engaged public sphere of debate to universalized rational procedures which he discusses in light of a philosophical notion of “detranscendentalization.” However, if it is the case that the solidarity of communities is being eroded by the influences of mass media and free market globalization as Habermas claims, then a further reflection on the way religious communities form around shared transcendent beliefs is required. Are his detranscendentalized rational procedures of critical debate adequate in inspiring the critical power communities need to solidify themselves against state authority? It is in light of this questions that I will develop the thought of Karl Barth. (shrink)

Schiller’s essays on tragedy attempt to argue that tragic experience is ethically valuable by forging a connection with Kant’s conception of autonomy. Standard interpretations hold that the connection lies in the fact that tragedies depict characters (primarily the hero) exercising autonomy. This paper argues that Schiller also views the experience prompted by tragedy as itself involving autonomy. Drawing on Kant’s discussion of aesthetic “symbols”, Schiller holds that the audience members’ experience at the tragedy is isomorphic with the autonomous exercise of (...) practical reason. Only in this way, I argue, can we make sense of Schiller’s contention that tragedy actively cultivates freedom in its viewers. Additionally, the interpretation shows how Schiller can hold that tragedy yields a kind of cognition of transcendental freedom while maintaining Kantian strictures on noumenal knowledge. (shrink)

While the clinical promise of much stem cell research remains largely theoretical, patients are nonetheless pursuing unproven stem cell therapies in jurisdictions around the world—a phenomenon referred to as “stem cell tourism.” These treatments are generally advertised on a direct-to-consumer basis via the Internet. Research shows portrayals of stem cell medicine on such websites are overly optimistic and the claims made are unsubstantiated by published evidence. However, anecdotal evidence suggests that parents are pursing these “treatments” for their children, despite potential (...) physical and financial risk. Physicians are in a unique position as they can be expected to be involved in, or privy to, such decisions. In this paper, we consider what duties physicians may have toward minor patients whose parents/guardians wish to engage in stem cell tourism on their behalf. We use the Canadian perspective to address the broadly relevant issues raised by this trend. (shrink)

Depuis le début de ce siècle, l'art et la littérature n'ont cessé de déborder leurs limites et de bousculer leurs catégories. Cette démarche radicale a contribué, en retour, à réveiller une théorie jusqu'alors quelque peu engourdie dans des conceptions héritées de la fin du XVIIIe siècle, aux confins des âges classique et romantique. Les études ici réunies témoignent de ce renouveau de l'esthétique, particulièrement dans la philosophie de tradition analytique. Leur trait commun est le caractère relativiste de leurs critères. Les (...) "symptômes" de la relation artistique sont de l'ordre de l'usage, de la circonstance, de la fonction : il n'y a d'oeuvre qu'à la rencontre d'une intention et d'une attention. Pour le public comme pour les créateurs, l'art est aussi une pratique. (shrink)

The Bible, a religious text, is also often said to be one of the foundation texts of Western culture. The present volume explores how religious, political and cultural identities, including ethnicity and gender, are embodied, often problematically, in biblical discourse. Following the authors, we read the Bible with new eyes: as a critic of gender, ideology, politics, and culture. We ask ourselves new questions: about God's body, about women's roles, about racial prejudices and about the politics of the written word.

As topics in the philosophy of emotion, pleasure and displeasure get less than their fair share of attention. On the one hand, there is the fact that pleasure and displeasure are given no role at all in many theories of the emotions, and secondary roles in many others.1 On the other, there is the centrality of pleasure and displeasure to being emotional. A woman who tears up because of a blustery wind, while an ill-advised burrito weighs heavily upon her digestive (...) tract, feels an impressive number of the sensations felt by someone who is gut-wrenchingly sad. Yet, unless she feels bad, the way she feels is only a pale echo of the feeling of sadness. If she feels good in spite of the burrito and the wind, then she does not feel at all the way she would if she were sad. Likewise, a man falling asleep can hardly fail to feel his muscles relax, his heart rate fall, and so on, but unless he feels good his state is only a shadow of feeling content. This paper will begin with a sketch of the nature of pleasure and displeasure, and the relation between them and the feelings that are characteristic of emotions. It will then argue that the capacity to feel pleased and displeased is, quite literally, a sense modality: one allowing us to perceive net change in the satisfaction of our intrinsic desires. As with any sense modality, the capacity to feel pleased and displeased displays substantial modularity. The paper concludes by considering the ways in which the modularity of pleasure and displeasure contributes to effects that might reasonably be called “the modularity of the emotions.”. (shrink)

A concept of informational equivalence between relations is explicated to generalize some suggestions by Geach. It is shown that two relations are informationally equivalent if and only if each can be defined in terms of the other without the use of quantifiers. It is shown that there is a general method for listing the ./-place relations informationally equivalent to an arbitrary given /-place relation if and only if i (...) the invariants of the group of invertible quantifier-free definitions, for / =j. Quantifier-free definition is contrasted with general first-order definition by means of an example of two first-order interdefinable relations which are not interdefined by any pair of mutually inverse first-order definitions. (shrink)

We review evidence from neuropsychological studies of patients with damage to the cerebellum that suggests cerebellar involvement in four general categories of cognition: (1) speech and language; (2) temporal processing; (3) implicit learning and memory; (4) visuospatial processing and attention. A relatively strong case can be made for cerebellar contributions to language (including speech perception, lexical retrieval, and working memory) and to temporal processing. However, the evidence concerning cerebellar involvement in non-motor implicit learning and visuospatial processing is more equivocal. We (...) argue that cerebellar contributions to cognition are computationally plausible, given its reciprocal connectivity with the cerebral cortex, and suggest that this function of the cerebellum may be an example of an evolutionary process by which mechanisms originally evolved for one function (in this case, motor control) are adapted to other functions (cognition). (shrink)

Jürgen Habermas has argued against prenatal genetic interventions used to influence traits on the grounds that only biogenetic contingency in the conception of children preserves the conditions that make the presumption of moral equality possible. This argument fails for a number of reasons. The contingency that Habermas points to as the condition of moral equality is an artifact of evolutionary contingency and not inviolable in itself. Moreover, as a precedent for genetic interventions, parents and society already affect children's traits, which (...) is to say there is moral precedent for influencing the traits of descendants. A veil-of-ignorance methodology can also be used to justify prenatal interventions through its method of advance consent and its preservation of the contingency of human identities in a moral sense. In any case, the selection of children's traits does not undermine the prospects of authoring a life since their future remains just as contingent morally as if no trait had been selected. Ironically, the prospect of preserving human beings as they are – to counteract genetic drift – might even require interventions to preserve the ability to author a life in a moral sense. In light of these analyses, Habermas' concerns about prenatal genetic interventions cannot succeed as objections to their practice as a matter of principle; the merits of these interventions must be evaluated individually. (shrink)

Through extensive readings in philosophical, legal, medical, and imaginative writing, this book explores notions and experiences of being a person from European antiquity to Descartes. It offers quite new interpretations of what it was to be a person—to experience who-ness—in other times and places, involving new understandings of knowing, willing, and acting, as well as of political and material life, the play of public and private, passions and emotions. The trajectory the author reveals reaches from the ancient sense of personhood (...) as set in a totality of surroundings inseparable from the person, to an increasing sense of impermeability to the world, in which anger has replaced love in affirming a sense of self. The author develops his analysis through an impressive range of authors, languages, and texts: from Cicero, Seneca, and Galen; through Avicenna, Hildegard of Bingen, and Heloise and Abelard; to Petrarch, Montaigne, and Descartes. (shrink)

Most advocates of biogenetic modification hope to amplify existing human traits in humans in order to increase the value of such traits as intelligence and resistance to disease. These advocates defend such enhancements as beneficial for the affected parties. By contrast, some commentators recommend certain biogenetic modifications to serve social goals. As Ingmar Persson and Julian Savulescu see things, human moral psychology is deficient relative to the most important risks facing humanity as a whole, including the prospect of Ultimate Harm, (...) the point at which worthwhile life is forever impossible on the planet. These risks can be mitigated, they say, by enhancing moral psychology in novel ways. Persson and Savulescu argue that some parents should modify the underlying biogenetics of their children's moral psychology, if such measures were safe and effective, but they admit these interventions may not decouple humanity from Ultimate Harm. Neither are these modifications the only options, they concede, for addressing risks to humanity. Even with these concessions, saving humanity from itself is a fairly poor reason to modify the moral psychology of children. In most ways, adults would be better candidates, morally speaking, for modifications of psychology. Even then, there is no direct link between morally enhanced human beings and the hoped-for effect of better protection from Ultimate Harm. Asserting a general duty of all to contribute to the avoidance of Ultimate Harm is a better moral strategy than intervening in the moral psychology of some, even though meeting that duty may involve substantial interference with the free exercise of one's interests. (shrink)

Antinatalist commentators recommend that humanity bring itself to a close, on the theory that pain and suffering override the value of any possible life. Other commentators do not require the voluntary extinction of human beings, but they defend that outcome if people were to choose against having children. Against such views, Richard Kraut has defended a general moral obligation to people the future with human beings until the workings of the universe render such efforts impossible. Kraut advances this view on (...) the grounds that we are obliged to exercise beneficence toward others and on the grounds that the goods available in human lives are morally compelling. This account ultimately succeeds in making no more than a prima facie defense of human perpetuation because considerations of beneficence could override – in some cases probably should – override any duty to perpetuate human beings. While the goods of human life may be distinctive, they cannot serve as reason-giving in regard to their own perpetuation. Ironically, the exercise of beneficence may authorize the extinction of human beings, if it becomes possible to enhance the goods available to human descendants in a way that moves them away from human nature as now given. The defense of a morally obligatory and strictly human future remains elusive, even as it becomes morally desirable to work against Fateful Catastrophes, those human-caused events that threaten to extinguish existing lives already good and enriching for their bearers. (shrink)

The primary transcripts, pre‐mRNAs, of almost all protein‐coding genes in higher eukaryotes contain multiple non‐coding intervening sequences, introns, which must be precisely removed to yield translatable mRNAs. The process of intron excision, splicing, takes place in a massive ribonucleoprotein complex known as the spliceosome. Extensive studies, both genetic and biochemical, in a variety of systems have revealed that essential components of the spliceosome include five small RNAs–U1, U2, U4, U5 and U6, each of which functions as a RNA, protein complex (...) called an snRNP (small nuclear ribonucleoprotein). In addition to snRNPs, splicing requires many non‐snRNP protein factors, the exact nature and number of which has been unclear. Technical advances, including new affinity purification methods and improved mass spectrometry techniques, coupled with the completion of many genome sequences, have now permitted a number of proteomic analyses of purified spliceosomes. These studies, recently reviewed by Jurica and Moore,1 reveal that the spliceosome is composed of as many as 300 distinct proteins and five RNAs, making it among the most complex macromolecular machines known. BioEssays 25:1147–1149, 2003. © 2003 Wiley Periodicals, Inc. (shrink)