The neural crest is a transient population of multipotent progenitors arising at the lateral edge of the neural plate in vertebrate embryos. After delamination and migration from the neuroepithelium, these cells contribute to a diverse array of tissues including neurons, smooth muscle, craniofacial cartilage, bone cells, endocrine cells and pigment cells. Considerable progress in recent years has furthered our understanding at a molecular level of how this important group of cells is generated and how they are assigned to specific lineages. (...) Here we review a number of recent studies supporting a role for Wnt signaling in neural crest induction, differentiation, and apoptosis. We also summarize the timing of expression of a number of Wnt ligands and receptors with respect to neural crest induction. BioEssays 25:317–325, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

For a long time now there have been different interpretations of the philosophical category "one divides into two." The debate that took place in scholarly circles in 1964 over "one divides into two" and "two combine into one" began with the question of how to interpret this category. At first this was a very lively and widespread scholarly debate. But later, because those "authorities on theory" who had at that time taken over the reigns of intellectual leadership within the Party (...) created contemporary superstitions that inhibited thought, the tone and boundaries of this debate became arbitrarily fixed and circumscribed so that this scholarly question became a political issue resulting in the criticism and trial of comrades such as Yang Xianzhen and the premature death of this debate. Today, in accordance with the spirit of the Third Session of the Eleventh Congress of the Central Committee of the Party, with an attitude of really searching for the truth, we must undertake a new and correct evaluation of this debate. Politically, we must overturn the false charges which were wrongly leveled at Comrade Yang Xianzhen and others, and intellectually, we must uphold the policy of "let a hundred schools contend, let a hundred flowers bloom." We must encourage the free discussion of different points of view, and we must avoid issuing hasty conclusions. All of us comrades who participated in this debate should accept the valuable experience and lessons learned from it. We want the debate on this question to truly become a widespread intellectual debate which will once again develop and move forward healthily. In this article I would simply like to talk about a few of my own views concerning the problem of how to correctly interpret "one divides into two.". (shrink)

Compared with traditional technological innovation modes, green technology innovation is more targeted for low carbon development and critical support for countries worldwide to combat climate change. The impact of green technology innovation on carbon emissions is considered in terms of fixed effect and mediating effect models through industrial structure upgrading. For this purpose, the sample dataset of 30 provincial administrative areas in China from 2008 to 2020 is employed. The results demonstrate that green technology innovation exerts significantly inhibitory effects on (...) carbon emissions, whose conclusion still holds after removing municipalities and replacing the dependent variable. Industrial structure upgrading is vital for green technology innovation to diminish carbon emissions. There is significant regional heterogeneity in the effects of green technology innovation on carbon emissions, i.e., the direct and indirect impact of green technology innovation on carbon emission reduction is significant in the eastern-central area, but its effect is insignificant in the western region. Therefore, it is essential to realize carbon emission reduction by further bolstering green technology innovation and accelerating industrial structure upgrading to fulfill the synergy of technology and structure. (shrink)

This paper discusses how a Platform for Philosophy Education can help to alleviate issues of alienation in the lives of university students. This is done through various personal cultivation and community building activities in the Academic Philosophy Café. The activities draw from philosophical traditions, including traditions with religious or “spiritual” elements. These encourage reflection on one’s place in the world. In addition, students and teachers cooperate to ensure the smooth running of the café and activities, which strengthens the community bond. (...) There is thus a “spiritual contract” formed between participants. In contrast to a written contract that binds parties by means of explicit rewards or sanctions, a “spiritual contract” is built on mutual understanding that higher-level needs will be met through the process of cooperation. Based upon this, a community is established that nourishes the lives of those on campus, benefits their wellbeing and strengthens their capacity to learn effectively. (shrink)

Neurological diseases (NDs), featured by progressive dysfunctions of the nervous system, have become a growing burden for the aging populations. N‐Deacetylase and N‐sulfotransferase 3 (NDST3) is known to catalyze deacetylation and N‐sulfation on disaccharide substrates. Recently, NDST3 is identified as a novel deacetylase for tubulin, and its newly recognized role in modulating microtubule acetylation and lysosomal acidification provides fresh insights into ND therapeutic approaches using NDST3 as a target. Microtubule acetylation and lysosomal acidification have been reported to be critical for (...) activities in neurons, implying that the regulators of these two biological processes, such as the previously known microtubule deacetylases, histone deacetylase 6 (HDAC6) and sirtuin 2 (SIRT2), could play important roles in various NDs. Aberrant NDST3 expression or tubulin acetylation has been observed in an increasing number of NDs, including amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), schizophrenia and bipolar disorder, Alzheimer's disease (AD), and Parkinson's disease (PD), suggesting that NDST3 is a key player in the pathogenesis of NDs and may serve as a target for development of new treatment of NDs. (shrink)

With the rapid development of renewable generators such as distributed photovoltaic and profound changes of the power structure, this paper analyzes the frequency characteristics of the power system with high penetration of renewable generations in the process of low-frequency load shedding and discusses the influence of the distributed renewable generator frequency endurance capabilities on the implementation effect of low-frequency load shedding in detail. Finally, the influences of the distributed renewable generator frequency endurance capability and the capacities of the distributed renewable (...) generator on frequency response characteristics of an actual Hunan power grid are simulated. The simulation results show that more distributed photovoltaic capacity without frequency endurance capability leads to deeper frequency drops after the disturbance and requires more basic rounds of load shedding. When the penetration rate of distributed photovoltaic is too high, it may cause load shedding, resulting in power grid load losses and, at the same time, leading to an overshoot phenomenon in the process of frequency recovery. Therefore, the influence of distributed photovoltaic on the control of low-frequency load shedding should be considered when designing low-frequency load shedding schemes for the power grid with high penetration of distributed photovoltaic. (shrink)

In order to improve the integrity of the social network behavior feature extraction results for sports college students, this study proposes to be based on the clustering algorithm. This study analyzes the social network information dissemination mechanism in the field of college students’ sports, obtains the real-time social behavior data in the network environment combined with the analysis results, and processes the obtained social network behavior data from two aspects of data cleaning and de-duplication. Using clustering algorithm to determine the (...) type of social network user behavior, setting the characteristics of social network behavior attributes, and finally through quantitative and standardized processing, get the results of college students’ sports field social network behavior characteristics extraction. The experimental results showed that the completeness of the method feature extraction results improved to 9.93%, and the average extraction time cost was 0.344 s, with high result integrity and obvious advantages in the extraction speed. (shrink)

Internet addiction is a growing social problem with negative mental and social outcomes; the present study examined whether rejection sensitivity mediates the relationship between interparental conflict and adolescent IA and the moderating role of school connectedness. One thousand and seven adolescents anonymously completed questionnaires to assess interparental conflict, school connectedness, rejection sensitivity, IA, and demographic information. The model results showed that: the positive association between interparental conflict and adolescent IA was partially mediated by rejection sensitivity; this indirect link was moderated (...) by the school connectedness and was stronger for adolescents with high school connectedness. The results provide support for the attachment theory that high interparental conflict could increase adolescents’ rejection sensitivity, and high school connectedness plays a double-edged role that adolescents show more rejection sensitivity while reporting high interparental conflict and high school connectedness. (shrink)

As the autonomous vehicles technology gradually enters the public eye, understanding consumers' psychological motivations for accepting autonomous vehicles is critical for the development of autonomous vehicles and society. Previously, researchers have explored the determinants of fully autonomous vehicles but the relevant research is far from enough. Moreover, the relationship between anthropomorphism and users' behavior has been ignored to a large extent. Therefore, this study aim to fill the gap by using anthropomorphism and the unified theory of acceptance and use of (...) technology to explore how system attributes and UTAUT attributes influence consumers' acceptance behavior. The data were collected via questionnaire survey conducted in Beijing, China, which can be a promising early adopter of AVs. Structural equation modeling was used to analyze the data. The results reveal that perceived anthropomorphism and perceived intelligence have a direct positive influence on the adoption of AVs; performance expectancy, effort expectancy, and facilitating conditions have an indirect positive influence on intention to adopt AVs. Also, this research contributes to the literature by enriching studies on psychological determinants of autonomous vehicles' adoption by taking an initial step to highlight anthropomorphism perceptions. This can provide managerial implications for policy-makers and businesses on how to effectively allocate resources to enhance autonomous vehicle adoption. (shrink)

Patients requiring deep brain stimulation due to intracerebral metallic foreign substances have not been reported elsewhere in the world. Additionally, the long-term effects of metallic foreign bodies on deep brain stimulation are unknown. A 79-year-old man with a 5-year history of Parkinson's disease reported that, 40 years ago, while playing with a pistol, a metallic bullet was accidentally discharged into the left brain through the edge of the left eye, causing no discomfort other than blurry vision in the left eye. (...) DBS was performed due to the short duration of efficacy for oral medication. Because the bullet was on the left subthalamic nucleus electrode trajectory and the patient's right limb was primarily stiff, the patient received globus pallidus interna -DBS implantation in the left hemisphere and STN-DBS implantation in the right hemisphere. During a 6-month postoperative follow-up, the patient's PD symptoms were effectively managed with no noticeable discomfort. (shrink)

As one of the key technologies for accelerating the construction of the ubiquitous Internet of Things, demand response not only guides users to participate in power market operations but also increases the randomness of grid operations and the difficulty of load forecasting. In order to solve the problem of rough feature engineering processing and low prediction accuracy, a short-term load forecasting model of LSTM neural network considering demand response is proposed. First of all, in view of the strong randomness and (...) complexity of input features, the weighted method is used to process multiple input features to strengthen the contribution of effective features and tap the potential value of features. Secondly, an improved genetic algorithm is used to obtain the best LSTM parameters; finally, the special gate structure of the LSTM model is used to selectively control the influence of input variables on the model parameters and perform load forecasting. The experimental results show that the research has high prediction accuracy and application value and provides a new way for the development of power load forecasting. (shrink)

The relationship between urban expansion and population density changes is complex and plays a fundamental role in urban sustainable development research. This relationship has been studied in multiple large cities. However, there is no report of the relationship of the two factors mentioned above in urban agglomeration in a particular region of China. Ten cities located in the central-southern region of Liaoning province are selected as research samples in this study. The spatial growth rate and urban compactness index of the (...) sample cities were calculated using the land use and population data of these cities in three time phases: 1995, 2005, and 2015. Then, the geographical growth features, the population density changes, and the link between these two in the sample cities were investigated at these three periods. Our results revealed that the studied cities of central-southern Liaoning province expanded at the three time phases under the driver of positive population density growth, but the effects of urban population change on urbanization growth modes across time were uneven across different periods. Our study showed a trend that active transition of different urbanization growth modes was associated with decreased population density. (shrink)

Ingratiation is a common strategy for subordinates to deal with their supervisors in eastern and western societies. Based on the theory of impression management, this study focuses on the impact of upward ingratiation outside the workplace on supervisor’s human resource decisions in the Chinese context and the mechanism behind this impact. The data were collected from 252 supervisor-subordinate dyads in four manufacturing firms. The results demonstrate the following: first, supervisors hold a more favorable view of upward ingratiation outside the workplace; (...) second, upward ingratiation outside the workplace has a positive effect on the supervisor’s chance of promotion and bonus allocation decisions, and leader-member exchange plays a mediation role in this influence; third, Zhongyong thinking moderates the relationship between LMX and supervisor’s chance of promotion and bonus allocation decisions; and finally, ZYT moderates the indirect effect of ingratiation behavior outside the workplace on supervisor’s chance of promotion and bonus allocation decisions through LMX, and the mediated relationship is weakened when a supervisor has a higher level of ZYT. This is one of the first empirical studies, which examines the validity of subordinate’s upward ingratiation outside the workplace from the perspective of supervisor’s ZYT. This study plays an important role in highlighting the effect of ZYT on the ingratiation behavior. (shrink)

This study aimed to develop the Three-Dimensional Filial Piety Scale and explore its psychometric properties. Based on Wang’s Three-Dimensional Filial Piety Model, our study employed a review of the current literature, in-depth interviews, and feedback from experts and the target group. An initial 36-item scale using a bipolar Likert 6-point rating scale was developed. Then item analysis and exploratory factor analysis were conducted with sample 1 (n = 617) to explore the dimensions and final items, and a 15-item scale (...) with three factors was obtained. After that, confirmatory factor analysis was conducted to validate the 3-factor structure obtained through exploratory factor analysis with sample 2 (n = 585). Next, we tested criterion-related validity with sample 3 (n = 248) and test-retest reliability with sample 4 (n = 67). The results supported the model on which this scale was based and showed three dimensions of filial piety, namely the balance of interests, good affections, and family role norms. As a valid, reliable scale, the Three-Dimensional Filial Piety Scale can therefore be used in the Chinese context to measure filial piety for people of different genders, ages, and cohabitation situations. (shrink)

With the advent of the era of artificial intelligence, “scenario” frequently appears in new product development and has gradually become an effective tool for analyzing user needs. However, the reasons for this phenomenon have not been explored in depth. New product development is a creative activity that requires product designers to imagine how people will live in the near future. So, we speculated that a familiar scenario that matches designers’ background can spark their entrepreneurial imaginativeness by empathic simulation and conducted (...) an experiment to research the impact of scenarios on the performance of entrepreneurial imaginativeness. Results of this study confirmed that a familiar scenario did indeed inspire entrepreneurial imaginativeness more than an unfamiliar scenario, especially for high entrepreneurial imaginativeness. This study provided a new respective for understanding the relationship between the empathy process and entrepreneurial opportunity recognition and evaluation processes and had practical implications for entrepreneurial practice, especially those that make human life better based on new digital technologies. Finally, we gave some suggestions on enhancing individuals’ entrepreneurial imaginativeness through different familiar scenarios and improving the team performance on creative tasks. (shrink)

The relationship between neuroticism and mobile phone use is a hot research topic in the academic community. The purpose of this study was to investigate the roles of self-emotional assessment and love status in the mechanism through which college students’ neuroticism influences mobile phone use.We construct a moderated mediation model, and taking 869 Chinese college students as the research object and testing the mediating role of self-emotional assessment and the moderating role of love status. The results show that: neuroticism was (...) significantly positively related to mobile phone use and significantly negatively related to self-emotional assessment; self-emotional assessment was significantly positively related to mobile phone use; self-emotional assessment had a masking effect on the relationship between neuroticism and mobile phone use; love status not only moderated the relationship between self-emotional assessment and mobile phone use but also moderated the process through which self-emotional assessment masked the effect of neuroticism on mobile phone use. Our research expands the literature on the mechanisms underlying the effects of neuroticism on mobile phone use, enriches the understanding of the pertinent boundary conditions, and provides a better explanatory basis for the mobile phone use of college students. (shrink)

Understanding the factors influencing the aesthetic experience of architectures is an important topic in empirical aesthetics. In this study, we examined the effect of three architectural factors, i.e., ceiling height, openness, and contour, on viewers’ aesthetic appreciation through a series of experiments. In previous studies on architectural aesthetics, participants were usually asked to view an image of an architectural space for a few seconds. The long viewing time allows them to focus on different parts of the architecture and then make (...) an aesthetic judgment. The long viewing time, however, also makes it difficult to obtain viewers’ aesthetic scores for a large number of architectural spaces in a short period. In this study, we shortened the visual presentation time to 200 ms, which allowed the viewers to have only one fixation on the image, and asked the viewers to make an aesthetic judgment. It was found that the experiment with a 200-ms viewing time could establish how the three architectural factors influenced aesthetic judgment as well as previous experiments with a 3,000-ms viewing time, suggesting that aesthetic judgment could be made within one fixation. Additionally, we investigated the impact of color on architectural aesthetic judgment by presenting grayscale images. We found that the three architectural factors influenced aesthetic judgment in similar ways for both color and grayscale images. In summary, we found that color was not a main factor modulating viewers’ architectural aesthetic judgments, and we also presented a way to quickly obtain aesthetic scores for architectural spaces. (shrink)

BackgroundVaccination has been considered one of the most effective public health interventions. In the context of the global epidemic of coronavirus disease 2019, it remains unclear what role general vaccination attitudes and perceptions have on the acceptance of COVID-19 vaccine.ObjectiveThis study aims to explore the impact of general attitudes and perceptions toward vaccination on the acceptance of a newly developed vaccine, taking COVID-19 vaccines as an example.MethodA cross-sectional survey was conducted among 2,013 Chinese adult participants. Generalized order logistic regression and (...) path analysis models were used to analyze impacts of general attitudes and perceptions toward vaccination on the acceptance of the COVID-19 vaccine.ResultsThe prevalence of hesitancy to vaccination in general is 49.9% among the Chinese adult population. General perceptions of vaccination were associated with corresponding perceptions of the COVID-19 vaccine. A “no hesitancy” attitude toward vaccination is a significant determinant of future COVID-19 vaccination compared to vaccine refusers, and perceptions of COVID-19 vaccine remain a significant determinant for the acceptance of the COVID-19 vaccine. Path analysis indicates that perceptions of the importance and safety of vaccination have a positive overall effect on the acceptance of the COVID-19 vaccine, and that general perceptions of vaccination as a whole on each measure indirectly influence the acceptance of the COVID-19 vaccine.ConclusionGeneral attitudes and perceptions toward vaccination were associated with those of the COVID-19 vaccine and future vaccination intention. To prepare for possible emergence of diseases in the future, routine health campaigns should be launched by relevant government departments and vaccination authorities to enhance the overall awareness and knowledge of vaccination among the public and to ensure optimal vaccination experience. In addition, targeted knowledge dissemination and mass mobilizations should be urged for newly developed vaccines when some specific infectious diseases emerge, such as COVID-19 at present. (shrink)

Optimization for vertical vibration performance of a rail-train coupling system is investigated in this paper with the introduction of inerters for both primary and secondary suspensions. A model of a typical Chinese passenger train that travels on a traditional rail with track, sleepers, and ballast is simulated. The goal is to improve the ride quality for the train and vibration attenuation for the rail system in response to track irregularities. Optimizations for only inertance and all suspension parameters are carried out (...) by the particle swarm algorithm. Performance benefits for both the train and the rail system are demonstrated and suspension layouts with inerters connected in parallel and series are compared with the traditional one in both time domain and frequency domain. (shrink)

Knowledge of the patterns of location of retail stores in urban areas supports the development of effective urban planning and the reasonable allocation of commercial facilities. Using point of interest data and consumer survey data in three main commercial districts in Changchun, China, this study investigates the spatial structures of commercial districts and the patterns of distribution of retail stores to assess the determinants of the development of retail stores in commercial districts. Kernel density estimation, nearest neighbor index, and Pearson’s (...) correlation analysis were used for this study. The following conclusions are drawn. The spatial distribution of retail stores in Changchun commercial districts generates the coexistence of a concentration in the core area and diffusion in the peripheral area. The emergence of shopping malls has challenged the traditional single-center structure, resulting in the transformation of commercial districts from single-center to multicenter layouts, while also producing a hierarchical trend in development. The Chongqing Road and Hongqi Street commercial districts have a relatively high spatial concentration of retail stores. Retail stores in Guilin Road exhibit distinct characteristics, namely, stores selling textiles, clothing, and daily necessities show the highest concentration, and food, beverage, and tobacco outlets as well as integrated stores show the lowest concentration. The selected locations of the differing categories of stores on Chongqing Road strongly correlate, and textile, clothing, and daily necessity stores show a high correlation with other retail categories. Four main factors affect the development and spatial layout of retail in the commercial districts. First, the interaction between consumer behavior and location choice in retail stores promotes the evolution of retail formats and trends in the development of comprehensive, specialized, and hierarchical retail commercial spaces. Second, the retail format determines the spatial layouts and the historical inheritance of the format. Third, governmental planning and policies lead to the agglomeration and diffusion of commercial activities in different areas. Fourth, such spatial clustering effects are an external driving factor for integration and aggregation among retail formats. (shrink)

Smartphone addiction behaviors are becoming more and more common with the rapid popularity and widespread use of smartphones. Such behaviors are significantly influenced by the overuse of smartphones before bedtime. In this study, the overuse of smartphones after 9:00 pm before bedtime was investigated by an online questionnaire. The sample consists of 1,035 college students in China. The artificial neural networks were applied to predict the use time of smartphones before bedtime based on their different usages, and the relationship between (...) smartphone usage and additive behaviors was analyzed. The results show that the neural network model can more accurately predict the usage time of smartphones according to the usage of smartphones before going to bed. At the same time, it is also found that the prediction accuracy of the samples that use the smartphone for less than half an hour and more than 3 h before bed is higher than that of other samples. Moreover, watching short videos and playing games are more likely to lead to mobile phone addiction behavior. These findings would help guide college students to correctly use phones and reduce smartphone addition, which is of great significance for mental health education. (shrink)

Name der Zeitschrift: Cognitive Linguistics Jahrgang: 27 Heft: 2 Seiten: 299-306.

The outbreak of COVID-19 at the end of 2019 has become the most devastating public health event of the 21st century. The different performances of governments and people in different countries and regions show that national values may play an important role in the prevention and control of COVID-19. Based on data from the seventh wave of World Values Survey and the Human Freedom Index report in 2020, three national value factors are extracted in this manuscript, including religious belief, government (...) satisfaction and individual freedom. Then ordinary least squares regression regression model is constructed to explore the influence of these three value factors on the prevention and control of COVID-19 and some heterogeneity analysis is implemented. The results show that religious belief and individual freedom significantly increased the COVID-19 infection rate, while government satisfaction significantly reduced the COVID-19 infection rate. The study findings have the ability to hold up after a range of robustness. For countries and regions with different COVID-19 testing policies, the influence of national values is different. Only in countries and regions with high testing rate policies and complete systems of the prevention and control of COVID-19, the influence of national values is significant. Based on these findings, a series of targeted policy recommendations for building national values in the post-epidemic era are proposed. (shrink)

本书论述了简单命题演绎推理,复合命题演绎推理、模态、命题演绎推理等的推理特点、规则、方法及其作用。.

With the rapid development of modern technology, people has stepped into an risky era. Ethical stipulation is the important means to reduce the risks. But in reality, ethical stipulation of technology always face some kind of dilemma which mainly come from two aspects: one is that when we try to regulate the subject oftechnology, we find that it always difficult to distinguish the responsibilities. The other aspect is that when we try to limit the result of technology, we often have (...) to give up because of lacking feasibility, which means we sink into the famous “Collingridge dilemma”. Are we able to get out of the dilemma? What should we doif we want to got out of it? First, in the modern technological system, individual’s action is taken over by group’s action according to the technological criterion. Any part of the modern technology need multiple subjects finish his job during the course. Therefore a new form of responsibility named group responsibility has been formed. Like Johnas said, in this ethics, ‘I’ will be replaced by ‘we’ and decision will be the business of a group. So it is difficult for us to find out that “I” from “us” once the technological risks happened. We lost the object of ethical stipulation as the result of no convinced standard and principals of prescribing the group responsibility. Second, when we try to stimulate some certain results of technology, we find we lack not only the wisdom of precisely judging or assessingtechnology itself, but also the ability of correcting the bad results if it has. Here again do we fall into the dilemma. This make it difficult for us to stipulate technology with ethic. From above discussion we can see, the stipulation, no matter from the aspect of technological responsibility or from aspect of the application of technology, has been sure to meet the dilemma. If the conflicts between a hypothesis and experiment cannot be eliminated, we have to rethink the theoryand come back again to technology itself and pursue the essence of technology again. Technology is a process from inventing, designing to forming material technological products; is a process from invisible technology to visible technology; is a process potential technology to real-life technology or intellective technology to reallife technology. Technology exists in process. The essential and innate characteristic is it’s process and dynamics. The transition oftechnological form involves many factors of economic, social, historical, constitutional and cultural. Technological creation of intellectual form is the duty of inventor or technologist. And it is entrepreneur’s job to use the technology or invention, and make them in large quantity, apply them in reality or get economic or other profit. Although there need be interaction, understanding, cooperation, support, coordination among scientist, technologist and enterpriser, they have different responsibility and delimitation. Technology exists in process, no doubt, so does modern technology. This decides that the ethical stipulation of modern technology should be a process stipulation. The essence of modern technological is not only the limitation of subject of technology either not only controlthe object of technology. It is the ethical stipulation in the unity of subject and object of technological dynamic process. This is basic point of understanding ethical stipulation of modern technology. Responsibility ethics consider that the group responsibility as the premise of technological stipulation.It noticed the static structure of modern technological system, but neglect the dynamic linkage between factors. And it only analysed the special construction, neglected the evolution of system of technological responsibility and the inter relationship between space dimension and time dimension. If we unfold the group responsibility along with the process of technology, we will see the different responsibility belong to different subject in different stage of the process. We can also see that different actors obey different norm or criteria according to their task. In this case, we can distinct the distribution of the group responsibility. Collingridge fixed the effective control on the two points of “before ”and ”after” the process of the technological action, namely, the stipulation for the staring point and stipulation of terminal point. But the whole process was neglected. According to the point of view of process stipulation.it is not the sudden occurrence for technology from “nothing ”to “having”. There are time and space during the process. From middle experiment to industrial experiment, the most characters of the result of technology will havebeen shown gradually, so will the social results. So we can give the small quantity an ethical evaluation and ethical choice which is possible and feasible. Over all, if we confirm the ethical stipulation of modern technology is a process regulation, we can delimitate the responsibility of the subjects of technology and also settle the prestipulation of the application of technology. At the end, we can eliminate the dilemma of ethical regulation of modern technology. (shrink)

Using logic analysis method with contemporary philosophy conception, made the definition of a life. Analyzing the reason of a disease and characteristics of drug, explained the Chinese traditional theory of materia medica. Demonstrated the best drug contain the function of Monarch drug, Minister drug, serviceman drug and missioner drug, instructed human drug reseach in future.

Hospitality industry plays a crucial role in the development of tourism. Predicting the future demand of a hotel is a key step in the process of hotel revenue management. Hotel passenger flow prediction plays an important role in guiding the formulation of hotel pricing and operating strategies. On the one hand, hotel passenger flow prediction can provide decision support for hotel managers and effectively avoid the waste of hotel resources and loss of revenue caused by the loss of customers. On (...) the other hand, it is the guarantee of the priority occupation of business opportunities by hotel enterprises, which can help hotel enterprises adjust their operation strategies reasonably to better adapt to the market situation. In addition, hotel passenger flow prediction is helpful to judge the overall operating condition of the hotel industry and assess the risk level of the hotel project to be built. Hotel passenger flow is affected by many factors, such as weather, environment, season, holidays, economy, and emergencies, and has the characteristics of complex nonlinear fluctuation. The existing demand predicting methods include linear methods and nonlinear methods. The linear prediction methods rely on the stability of environment and time series, so they cannot completely simulate the complex nonlinear fluctuations characteristics of hotel passenger flow. Traditional nonlinear prediction methods need to improve the prediction accuracy, and they are difficult to deal with the increasing data of hotel passenger flow. Based on the above analysis, this paper constructs a deep learning prediction model based on Long Short-Term Memory to predict the number of actual monthly arrival bookings. The number of actual monthly arrival bookings can reflect the actual monthly passenger flow of a hotel. The prediction model can effectively reduce the loss caused by cancellation or nonarrival of bookings due to various reasons and improve the hotel revenue. The experimental part of this paper is based on the booking demand dataset of a resort hotel in Portugal from July 1, 2015, to August 31, 2017. Artificial neural network and support vector regression are built as benchmark models to predict the number of actual monthly arrival bookings of this hotel. The experimental results show that, compared with the benchmark models, the LSTM model can effectively improve the prediction ability and provide necessary reference for the hotel's future pricing decision and operation mode arrangement. (shrink)