Taking advantage of the fact that they need not replicate their DNA, terminally differentiated neurons only repair their expressed genes and largely dispense with the burden of removing damage from most of their genome. However, they may pay a heavy price for this laxity if unforeseen circumstances, such as a pathological condition like Alzheimer's disease, cause them to re‐enter the cell cycle. The lifetime accumulation of unrepaired lesions in the silent genes of neurons is likely to be significant and may (...) result in aborting the mitotic process and triggering cell death if the cells attempt to express these dormant genes and resume DNA replication. BioEssays 25:168–173, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Valorising the biocultural heritage of common goods could enable peasant farmers to achieve socially and economically inclusive sustainability. Increasingly appreciated by consumers, peasant heritage products offer small farmers promising opportunities for economic, social and territorial development. Identifying the obstacles and levers of this complex, multi-scale and multi-stakeholder objective requires an integrative framework. We applied the panarchy conceptual framework to two cases of participatory research with small quinoa producers: a local fair in Chile and quinoa export production in Bolivia. In both (...) cases, the “commoning” process was crucial both to bring stakeholders together inside their communities and to gain outside recognition for their production and thus achieve social and economic inclusion. Despite the differences in scale, the local fair and the export market shared a similar marketing strategy based on short value chains promoting quality products with high identity value. In these dynamics of biocultural heritage valorisation, the panarchical approach revealed the central place as well as the vulnerability of the community territory. As a place of both anchoring and opening, the community territory is the privileged space where autonomous and consensual control over the governance of common biocultural resources can be exercised. (shrink)

Le Quichotte de Cervantès occupe une place singulière dans l’histoire de la traduction littéraire en langue française, au moins parce qu’il a fait l’objet d’incessantes retraductions. Mais l’ouvrage retient l’attention parce que la traduction y est thématisée pour elle-même en deux endroits. Cervantès, en jouant avec les codes du roman de chevalerie, pose le cadre général d’une réflexion théorique sur la traduction dont on cherchera ici à souligner les principales tensions constitutives. En intériorisant ses propres origines fictives et traductives, dans (...) un intermède à cheval entre les chapitres viii et ix, le Quichotte évoque à la fois l’idée d’une traduction impossible, mais aussi celle de la traduction comme une modalité particulière de lecture où s’origine la littérature moderne comme quasi-monde (Ricœur) propice aux échanges textuels. Il s’agira finalement de montrer que, ce faisant, Cervantès fait signe à la fois vers le structuralisme et la tradition herméneutique, et leur articulation problématique. (shrink)

We introduce the notion of Boolean measure algebra. It can be described shortly using some standard notations and terminology. If B is any Boolean algebra, let BN denote the algebra of sequences , xn B. Let us write pk BN the sequence such that pk = 1 if i K and Pk = 0 if k < i. If x B, denote by x* BN the constant sequence x* = . We define a Boolean measure algebra to be a Boolean (...) algebra B with an operation μ:BN → B such that μ = 0 and μ = x. Any Boolean measure algebra can be used to model non-principal ultrafilters in a suitable sense. Also, we can build effectively the initial Boolean measure algebra. This construction is related to the closed open Ramsey Theorem 193–198.). (shrink)

"Based on the reading of the only twelfth-century manuscript of the Enigma extant, Charleville MS. 114, and an examination of the fifteenth-century manuscript Uppsala C. 79." Revision of the editor's thesis, Catholic University of America, 1971, presented under title: The enigma fidei of William of Saint Thierry, a translation and commentary. Bibliography: p. 119-120.

Formal topology aims at developing general topology in intuitionistic and predicative mathematics. Many classical results of general topology have been already brought into the realm of constructive mathematics by using formal topology and also new light on basic topological notions was gained with this approach which allows distinction which are not expressible in classical topology. Here we give a systematic exposition of one of the main tools in formal topology: inductive generation. In fact, many formal topologies can be presented in (...) a predicative way by an inductive generation and thus their properties can be proved inductively. We show however that some natural complete Heyting algebra cannot be inductively defined. (shrink)

continent. 2.3 (2012): 224–228 Introduction Jamie Allen Thierry Geoffroy’s conceptual, event- and environment-based art practice has generated over two-decades of definitional activity around what he terms “format art.” The works re-galvanize the energies of a syndicatable, open and atmospheric arrangement, of varying specifics dependent on context, participants and environment. With formats like the Emergency Room, Biennalist, and the Critical Run, Geoffroy endeavors to imbricate art and artist in the most exigent and current of social, political and mediatised spectacles. The (...) result seems to plant us at a triangulation of the configurations proposed by Alan Kaprow, Andrea Fraser and Alan Abel. Geoffroy plays up a guileless innocence (at times sporting the “Naive Blue Helmet”) as he interviews spectactors at the 2012 dOCUMENTA13 exhibitions in Kassel, Germany. What he evokes is a declamation of the appropriative, unenthusiastic, cool inclinations of the mainstream art festival, the profligate biennial (triennial, quadrennial, etc.) circuit and national and global ideological cultural-engines. In propositional artifacts, definitional articles and direct transmissions from Geoffroy’s Emergency Room field office at dOCUMENTA13, the masking of an emergency is here questioned: Can an art show like dOCUMENTA be dangerous? —JA Is dOCUMENTA designed to make people cry about something and not make them see something else? Is the contemporary a distraction from the present? Can art in delay have any impact with today? Do we learn anything by seeing art shows reflecting on history? Could 860,000 visitors have been intoxicated by an apathic gaze than keep them away from reacting? Why is dOCUMENTA proud of having recieve no critic? Why is proximity less important? Why was dOCUMENTA in Kabul? Can weapons designed to kill protesters sold to a repressing regime be contradictory to the support of the Arab Spring? Is the contemporary like a flea market to avoid to debating the important topics of today? Can art be in advance of the broken arm, and avoid accident? Is the goal of dOCUMENTA to create a revolution or to entertain? Is dOCUMENTA betterly done than Disney Land? Is it better to watch Fox News for two years or to go to dOCUMENTA for two days? If a curator, curating a contemporary art show about war, forgets to debate about the weapons factories next door, should it be considered as a professional mistake? Is it OK to employ philosophers to promote vodka? Is navigation a threat? Can an art show like dOCUMENTA be dangerous? Thierry Geoffroy / Colonel author of the month Global Art and the Museum @ZKM: " THE NEXT DOCUMENTA SHOULD BE CURATED BY A TANK " Link to Emergency Room Dictionary < /a> "COOLNESS" from the EMERGENCY ROOM DICTIONARY by COLONEL MUSIC Biennalist at dOCUMENTA 13 "TIRED" from the EMERGENCY ROOM DICTIONARY by COLONEL MUSIC Link to " APATHY " (from the Emergency Room Dictionary ) AWARENESS MUSCLE [fr. muscle de la conscience ] In the same sense memory can be trained, an awareness muscle can be developed by an effort. To develop the awareness muscle, the artist has to reduce his gesticulations. When an artist is busy the artist is not very aware the artist is occupied. A daily training is necessary But how to train? Scanning the news in a critical way could be one exercise. Daily debating politics with others could be another. Looking at other point of views usually produces significant improvements. Fighting prejudice is an excellent exercise. Many other forms of training could also produce beneficial effects for the awareness muscle. Continuous and daily training is important. For instance rewinding and slow motioning what has been absorbed getting away the sugar from the propaganda machines talking to everyone excercise comparatif critical run. If not daily trained the awareness muscle can degrade into atrophy To develop the awareness muscle requires will-power Thierry Geoffroy / Colonel. (shrink)

This paper argues that some words are so highly charged with meaning by a community that they may prevent a discussion during which each participant is on an equal footing. These words are indeed either unanimously accepted or rejected. The presence of these adjectival groups pushes the antagonist to find rhetorical strategies to circumvent them. The main idea we want to develop is that some propositions are not easily debatable in context because of some specific value-bearing words, and one of (...) the goals of this paper is to build a methodological tool for finding and classifying these VBWs. Our study echoes the importance of “cultural keywords” in argument, but is rather based on a German approach developed by,, and about “Miranda” and “Anti-Miranda” words that is expanded and refined here. In particular, our study tries to understand why some statements, fueled by appreciative or evaluative adjectives, have such rhetorical effects on a pragmatic level in the particular context of a vote on the Swiss popular initiative called “for more affordable housing”. This context is fruitful since two parties offer reasons for two opposing policy claims: namely, to accept or to reject an initiative. When one party uses arguments containing such universally unassailable adjectival groups to defend a “yes” vote, the opposing party cannot use a symmetrical antonym while pleading for the “no” vote. The methodological tool that is proposed here could shed light on the use of certain rhetorical and referential strategies in conflicting policy proposition contexts. (shrink)

Etudier le probleme de la personne, c'est s'interesser a un probleme qui traverse a peu pres tous les domaines de la philosophie, depuis la psychologie jusqu'a la theologie en passant par l'ethique et par le droit, mais dont le denominateur commun est la definition du soi-meme. Etudier ce probleme chez Maimonide, c'est voir comment un philosophe juif du Moyen-Age pouvait elaborer une representation coherente de l'homme en s'appuyant a la fois sur la pensee greco-arabe et sur la tradition hebraique. Ce (...) livre espere contribuer a une meilleure comprehension d'un philosophe dont on a trop souvent fragmente la pensee, apparemment dechiree entre des sources contradictoires. En fait, Maimonide a su developper un dialogue critique entre deux heritages qui demeurent aux fondements de la civilisation occidentale. C'est ce qui donne a sa pensee son caractere eminemment actuel. (shrink)

Cette étude analyse les réponses orales de 63 élèves français de 9-11 ans lors d’une tâche de vocabulaire du type définition de mots. La performance globale, mais aussi l’organisation et l’accessibilité des informations catégorielles, fonctionnelles ou perceptives sont examinées en considérant l’origine sociale des enfants. Les résultats quantitatifs de l’étude confirment ceux obtenus par les recherches sur la relation entre milieu socio-économique et étendue du vocabulaire. Les données qualitatives, tirées de l’analyse de la structure de 567 définitions, mettent en évidence (...) des différences modérées de l’évolution vers la forme canonique de la définition, selon la classe sociale. Ceci interroge nos manières de penser l’enseignement-apprentissage du vocabulaire et invite à explorer plus avant les mécanismes en jeu dans l’inégal accès à la connaissance de la signification des mots. (shrink)

Rendell & Whitehead's minimalist definition of culture does not allow for the important gaps between cetaceans and humans. A more complete analysis reveals important discontinuities that may be more instructive for comparative purposes than the continuities emphasized by the authors.

This article explores urban dwellers’ perceptions of climate change and their propensity to act ecologically. It argues that a better understanding of people's moral and psychological functioning toward ecology could guide the creation of more suitable environmental management strategies. The study is based on semi-structured interviews investigating the environmental values of urban inhabitants; the interviews were conducted in 2018, in a coastal French area affected by recurring floods. Our results showed no significant relationships among the three studied factors of experiencing (...) natural hazards, becoming aware of sustainable issues and developing intentions to ‘act green’. In fact, these last two aspects depended mainly on informal education and socio-economic conditions. Using a ‘heuristic of fear’ (Jonas 1984) to develop sustainability practices is therefore inefficient, at best. Instead, practical efforts should be centred on upbringing, education, self-efficacy and socio-economic and political regulations, especially in a country like France where people are historically used to welcoming collective regulations by the Welfare State. (shrink)

Cet ouvrage a pour enjeu de débattre du schéma théorique forgé par Alfred Schütz, promoteur de l'idée de sociologie phénoménologique (puisant son cadre analytique dans une lecture de la sociologie compréhensive weberienne, de la philosophie de la durée bergsonienne, et de la phénoménologie husserlienne). Les catégories princeps de la recherche sont dès lors celles de conscience, de temporalité et de signification. La structure phénoménologique de l'expérience sociale, l'essence de la compréhension intersubjective, les perspectives offertes par les tenants d'une sociologie formiste (...) en matière d'entendement de l'interaction, sont les thèmes majeurs de ce débat. Dans le cadre de cette lecture, Thierry Blin tente d'établir les principes d'une sociologie phénoménologique formiste ou structurale, permettant ainsi de fonder à nouveaux frais une sociologie de l'action. (shrink)

The review adresses the relationship between sport expertise (i.e., sport competition level), postural performance (amount of motion of the centre of mass/of pressure of foot or ability to preserve body balance) and postural strategy (geometric organization of different body segments as well as neurobiological involvement of organism). Since the conditions of postural evaluation are likely to influence results, the aim is to compare athletes at different competition levels in ecological postural conditions (specific postural conditions related to the sport practiced) and (...) non-ecological postural conditions (decontextualized postural conditions in relation to the sport practiced). Evidence suggests that the most successful athletes in terms of sport competition level have the best postural performance both in ecological and non-ecological postural conditions. However, in non-ecological conditions the postural tasks should be preferentially challenging or relatively close to the sport practice stance. Moreover, the most successful athletes also have more elaborate postural strategies compared with athletes at lower competition level. Mechanistic explanations as well as conceptual models are proposed to explain the role of different factors influencing the relationship between sport expertise and postural performance and strategy. (shrink)

While "natural history" is practically synonymous with the name of Buffon, the term itself has been otherwise overlooked by historians of science. This essay attempts to address this omission by investigating the meanings of "physique," "natural philosophy," and "history," among other terms, with the purpose of understanding Buffon's actual objectives. It also shows that Buffon never claimed to be a Newtonian and should not be considered as such; the goal is to provide a historical analysis that resituates Buffon's thought within (...) his own era. This is done, primarily, by eschewing the often-studied question of time in Buffon. Instead, this study examines the nontemporal meanings of the word "history" within the naturalist's theory and method. The title of his Natural History is examined both as an indicator of the kind of science that Buffon was hoping to achieve and as a source of great misinterpretation among his peers. Unlike Buffon, many of his contemporaries actually envisioned the study of nature from a Baconian perspective where history was restricted to the mere collection of facts and where philosophy, which was the implicit and ultimate goal of studying nature, was seen, at least for the present, as unrealizable. Buffon confronts this tendency insofar as his Histoire naturelle claims to be the real physique that, along with describing nature, also sought to identify general laws and provide clear insight into what true knowledge of nature is or should be. According to Buffon, history (both natural and civil) is not analogous to mathematics; it is a nonmathematical method whose scope encompasses both nature and society. This methodological stance gives rise to the "physicization" of certain moral concepts--a gesture that was interpreted by his contemporaries as Epicurean and atheist. In addition, Buffon reduces a number of metaphysically tainted historical concepts (e.g., antediluvian monuments) to objects of physical analysis, thereby confronting the very foundation of natural theology. In Buffon, as this essay makes clear, natural history is paving the way for a new physique (science of natural beings), independent from mathematics and from God, that treats naturalia in a philosophical and "historical" manner that is not necessarily "temporal. ". (shrink)

In this interview, Anne Fagot-Largeault discusses with Thierry Bardini her recollections of the life and work of French philosopher Gilbert Simondon (1924–1989). The discussion covers Simondon’s theory of individuation and considers its influences on contemporary thinkers such as Gilles Deleuze and François Laruelle. Fagot-Largeault situates Simondon’s thinking within the broader context of 20th-century biological research and the development of life sciences. Informed by her personal association and experiences working with Simondon, her reminiscences shed light on the unique character of (...) Simondon as a person and as a thinker. (shrink)

The aim of this volume is to provide an exhaustive and updated analysis and discussion of the philosophy of Liang Shuming 梁漱溟 (1893–1988), one of the most contested figures of modern Chinese intellectual history. For the last 100 years, his thought has been interpreted in such contrasting and contradictory ways—as Buddhist, Confucian, and Marxist, as conservative and modernist—that it seems at times difficult to grasp who the “real” Liang was. Confronted with the many faces of the man and his thought, (...) researchers can either attempt to discern the one identity that ties them all together or allow for the multifaceted nature of his thought to remain open and focus on the diversity and tensions inherent in it. The present volume opts for the latter option. (shrink)

Résumé — La notion de prophétie joue dans l’œuvre de Machiavel un rôle qu’on ne saurait minimiser. Cet article propose d’étudier la fonction de cette notion en relation avec la politique et avec la représentation machiavélienne de l’histoire. L’article met enfin l’accent sur les liens entre celle-ci et la pensée de l’événement.— The notion of the prophecy in Machiavelli’s work plays a role which can’t be underestimated. This article studies the function of this notion relating to politic and Machiavellian representation (...) of History. Lastly the article shows the links between this one and the thought of event. (shrink)

The romance customarily termed “classical” occupies a special place within Cambodian literature as a whole. The term betrays a certain Eurocentrism and is justified only because the written language of this type of text is neither the old Khmer of epigraphic inscriptions, nor modern Khmer, but the form of the language known as “middle Khmer,” which in theory designates the period from the fourteenth century through the end of the nineteenth century, and of which we have written records from the (...) eighteenth and nineteenth centuries, in the romances as we know them. While these romances share one significant feature with Khmer literature as a whole, they are distinguished by other characteristics that are peculiar to them. (shrink)

The concept of corporate social responsibility is a relatively recent addition to the agenda in Germany, although the country has a long history of companies practicing social responsibilities. The expectations of society had remained stable for many years, encapsulated in laws, societal norms, and industrial relations agreements. But the past decade has seen significant changes in Germany, challenging established ways of treating the role of business in society. This contribution reviews and illustrates the development of diverse forms of social responsibility (...) in German corporations and analyzes how actors in business and society can build on traditional strengths to find new institutional arrangements for sharing tasks and responsibilities in the interests of achieving a better balance between societal, economic, and environmental needs. (shrink)

Thierry Meynard examines how the Jesuits in China came to understand the Confucian tradition, and how they offered the first complete translation of the Lunyu in the West, in the Confucius Sinarum Philosophus.