We are appreciative of the broad range of commentaries our target article generated. The inquiry into the contingency phase of public health emergencies is nascent and the cl...

Rare work, with anonymous incomplete commentary, on the fundamentals of the Mimamsa school in Hindu philosophy; ascribed to Kumārila Bhaṭṭa.

The Bush doctrine of preventive and pre-emptive strikes triggered a debate in academic and governmental circles about the possible legitimization of those concepts in international politics and possibly international law. This essay gives an overview of the practice of preventive and pre-emptive strikes, both before and after the Cold War. Further, it sketches the above-mentioned debate and the underlying trends explaining it. Finally, it assesses the new doctrine in light of a possible future incorporation of the concepts of preventive and (...) pre-emptive strikes into international law. A distinction will be made between three kind of preventive strikes: counter-terrorist, counter-proliferation, and preventing humanitarian disasters. (shrink)

Since the 1950s we have had the same three neurotransmitters to work with to treat depression, one transmitter for psychoses, three for anxiety. We have developed newer drugs that are more tolerable, but we have not developed drugs that are better in efficacy. The last 50-60 years should be considered the decades that allowed us to treat a greater number of patients with safer and more tolerable drugs. We have also decreased stigma and allowed primary care clinicians to become more (...) comfortable treating the mentally ill. We clearly treat more patients than before, and sometimes are now accused of over-prescribing wantonly as our drugs are safer. Without any clear blockbuster new drug ready to be added to our armamentarium, what can we do as psychopharmacologists today, and tomorrow, to obtain better results? This introductory manuscript will attempt to provide an overview of ideas so that an adept, well-rounded clinician might be able to obtain better outcomes despite using neurotransmitter pharmacodynamics that have been around since the 1950s. Finally, I will comment on the psychotropic pipeline, which may be added to our armamentarium in the future. (shrink)

Asconius 63 , commenting on the pro Cornelio: Fuerunt enim plures Quinti Metelli, ex quibus duo consulares, Pius et Creticus, de quibus apparet eum non dicere, duo autem adulescentes, Nepos et Celer, ex quibus nunc Nepotem significat. Eius enim patrem Q.Metellum Nepotem, Baliarici filium, Macedonici nepotem qui consul fuit cum T. Didio, Curio is de quo loquitur accusavit … Cicero and his scholiast refer to ‘duo Metelli, Celer et Nepos’ but like Asconius do not specify their relationship. Celer himself, followed (...) by Cicero in correspondence with him, calls Nepos his frater, but since both bore the praenomen Q., this cannot be the whole story. Celer's career shows that he was the elder, yet Nepos senior, according to Asconius, entrusted his feud with Curio not to him but to Nepos iunior. (shrink)

1. 'P'osŭt'ŭ' tamnon ŭi yuryŏngdŭl : aedo ŭi aedo rŭl wihayŏ -- 2. Chwap'a mesiajuŭi ranŭn irŭm ŭi yongmang : 'p'osŭt'ŭ-p'osŭt'ŭ tamnon' ŭi kungnae suyong e taehayŏ -- 3. Sigan kwa chŏngŭi : Penyamin, Haidegŏ, Terida -- 4. Kungmin iranŭn noye : chŏnch'ejuŭijŏk kungmin kukkaron e taehan pip'anjŏk koch'al -- 5. Ŏttŏn sangsang ŭi kongdongch'e : minjok, kungmin kŭrigo kŭ nŏmŏ -- 6. Hanbando p'yŏnghwa ch'eje ŭi (t'al) kuch'uk ŭl wihayŏ : ŭl ŭi minjujuŭi ŭi kwanchŏm esŏ -- 7. P'uk'o (...) wa minjujuŭi : pakkat ŭi chŏngch'i, sinjayujuŭi, taehang p'umhaeng -- 8. Marŭk'ŭsŭ wa Alt'wiserŭ sai ŭi P'uk'o -- 9. (T'al) hyŏndae ihu, Marŭk'ŭsŭjuŭi ihu : Terida, K'ojellek, Ch'ak'ŭrabarŭt'i, kŭrigo kŭ nŏmŏ -- 10. Ch'akch'wi, paeje, rip'ŭrijent'eisyŏn : Marŭk'ŭsŭjuŭi ŭi t'alguch'uk. (shrink)