We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

This book is a clear and concise history of the soul in western philosophy, from Plato to cutting-edge contemporary work in philosophy of mind. Packed with arguments for and against a range of different, historically significant philosophies of the soul Addresses the essential issues, including mind-body interaction, the causal closure of the physical world, and the philosophical implications of the brain sciences for the soul's existence Includes coverage of theories from key figures, such as Plato, Aquinas, Locke, Hume, and Descartes (...) Unique in combining the history of ideas and the development of a powerful case for a non-reductionist, non-materialist account of the soul. (shrink)

In this paper, I develop a noncausal view of agency. I defend the thesis that choices are uncaused mental actions and maintain, contrary to causal theorists of action, that choices differ intrinsically or inherently from nonactions. I explain how they do by placing them in an ontology favored by causal agency theorists (agent-causationists). This ontology is one of powers and liabilities.After explicating how a choice is an uncaused event, I explain how an adequate account of freedom involves the concept of (...) choosing for a reason. Choosing for a reason is a teleological notion, and I set forth what is involved in making a choice for a purpose. (shrink)

Whilst Rahimzadeh et al. (2023) apply a critical lens to the pedagogical use of LLM bioethics assistants, we outline here further reason for skepticism. Two features of LLM chatbots are of signific...

This chapter contains sections titled: Locke Butler Reid Hume Kant.

David Widerker has forcefully argued that a libertarian is on firm ground in believing that the principle of alternative possibilities (PAP) is true. Eleonore Stump has argued that not all libertarians need accept PAP, and that its acceptance is not required for a rejection of compatibilism.This paper is a defense of Widerker against Stump. I argue that it is not at all clear that Stump’s view of freedom is libertarian in nature, and that she has not provided a good reason (...) for thinking that a libertarian can abandon PAP. (shrink)

While William Hasker and I for the most part broadly agree in our opposition to much of the contemporary philosophical community concerning issues in the philosophy of mind that he discusses in his book, there are nevertheless seemingly some domestic disputes between him and me about certain matters concerning the nature of events involving the self. In this paper, I will focus on two of these disagreements. The first disagreement concerns Hasker’s treatment of what is widely known today as the (...) argument from reason and whether the events involved in our reasoning are essentially causal or teleological in nature. The second disagreement is about Hasker’s account of libertarian freedom, and whether agent causation is required to explain our free choices. (shrink)

If we have libertarian free will, then it is plausible to believe that the occurrences of certain physical events have irreducible and ineliminable mental explanations. According to a strong version of naturalism, everything in the physical world is in principle explicable in nonmental terms. Therefore, the truth of naturalism implies that libertarian choices cannot explain the occurrences of any physical events. In this paper, I example a methodological argument for the truth of naturalism and conclude that the argument fails. I (...) then consider additional concerns raised against the reality of libertarian freedom. First, I examine the claim that if a physical event E is not causally determined to occur by another physical event, then there is no way to account for the difference between E’s occurring randomly and E’s being causally determined to occur by a mental event. Second, I consider the assertion that the affirmation of libertarianism is a mind-of-the-gaps version of the God-of-the-gaps objection to a divine explanation of a physical event. Third, I take up the question of whether the inability of libertarians to pinpoint precisely where the initial physical effects of libertarian choices occur is a good reason for rejecting libertarianism. Fourth, I examine the claim that belief in the existence of the soul or immaterial mind is the result of an explanatory hypothesis to account for how libertarian free choices can causally produce physical effects. Fifth, I look at the traditional objection to substance dualism from the impossibility of causal interaction between a soul and its body. (shrink)

In this article I shall concern myself with the question ‘Is some type of justification required in order for belief in God to be rational?’ Many philosophers and theologians in the past would have responded affirmatively to this question. However, in our own day, there are those who maintain that natural theology in any form is not necessary. This is because of the rise of a different understanding of the nature of religious belief. Unlike what most people in the past (...) thought, religious belief is not in any sense arrived at or inferred on the basis of other known propositions. On the contrary, belief in God is taken to be as basic as a person's belief in the existence of himself, of the chair in which he is sitting, or the past. The old view that there must be a justification of religious belief, whether known or unknown, is held to be mistaken. One of the most outspoken advocates of this view is Alvin Plantinga. According to Plantinga the mature theist ought not to accept belief in God as a conclusion from other things he believes. Rather, he should accept it as basic, as a part of the bedrock of his noetic structure. ‘The mature theist commits himself to belief in God; this means that he accepts belief in God as basic.’. (shrink)

According to N. T. Wright, anyone who is a Christian should at least think twice before he or she speaks about the soul, especially as an entity that is distinct from its physical body and can survive death in a disembodied intermediate state until the resurrection and reembodiment. In Wright’s mind, talk of the soul is talk about soul-body substance dualism (dualism, for short), which is the villain in Christian anthropological thought. As far as Wright is concerned, it is time (...) for Christians to renounce dualism once and for all. In this paper, I take issue with Wright’s position on substance dualism. (shrink)

‘Gender’, understood as the social construction of sex, is a key concept for feminists working at the interface of theory and policy. This article examines challenges to the concept which emerged from different groups at the UN Fourth World Conference on Women in Beijing, September 1995, an important arena for struggles over feminist public policies. The first half of the article explores contradictory uses of the concept in the field of gender and development. Viewpoints from some southern activist women at (...) the NGO Forum of the Beijing Conference are presented, Some of them argued that the way ‘gender’ has been deployed in development institutions has led to a depoliticization of the term, where feminist policy ambitions are sacrificed to the imperative of ease of institutionalization. ‘Gender’ becomes a synonym for ‘women’, rather than a form of shorthand for gender difference and conflict and the project of transformation in gender relations. ‘Gender sensitivity’ can be interpreted by non-feminists as encouragement to use gender-disaggregated statistics for development planning, but without consideration of relational aspects of gender, of power and ideology, and of how patterns of subordination are reproduced. A completely different attack on ‘gender’ came from right-wing groups and was battled out over the text of the Platform for Action agreed at the official conference. Six months prior to the conference, conservative groups had tried to bracket for possible removal the term ‘gender’ in this document, out of opposition to the notion of socially constructed, and hence mutable, gender identity. Conservative views on gender as the ‘deconstruction of woman’ are discussed here. The article points out certain contradictions and inconsistencies in feminist thinking on gender which are raised by the conservative backlash attack on feminism and the term ‘gender’. (shrink)

In this paper, I argue that a commitment to science and the methodo- logical commitment to causal closure do not require a rejection of the idea that the choices of souls explain the occurrence of certain events in the physical world. Stated slightly differently, I maintain that one can both affirm science and believe that souls causally interfere in the course of events in the physical world. Such an affirmation and belief are compatible. In short, science vis-à-vis the methodological principle (...) of causal closure poses no problem for souls as explanatory agents. (shrink)

This chapter contains sections titled: Causation and Dualism Why Not Locate Souls in Space? Property/Event Dualism or Dual Aspect Theory.

This chapter contains sections titled: The Simple View The Teleological View The Qualitative View Objections Concluding Remarks Works cited.

The fan effect says that “activation” spreading from a concept is divided among the concepts it spreads to. Because this activation is not a physical entity, but an abstraction of unknown lower‐level processes, the spreading activation model has predictive but not explanatory power. We provide one explanation of the fan effect by showing that distributed neuronal memory networks (specifically, Hopfield networks) reproduce four qualitative aspects of the fan effect: faster recognition of sentences containing lower‐fan words, faster recognition of sentences when (...) more cues are provided, faster acceptance of studied sentences than rejection of probes, and faster recognition of sentences studied more frequently. These are all a natural result of the dynamics of distributed associative memory. (shrink)

This chapter contains sections titled: The Ghost in the Machine Objection The Private Language Argument Ockham's Razor and Identity Argument from Neural Dependence Arguments from Personal Identity Argument from Evolution.

The nature of choice and its relation to events in the material world are the subjects of this chapter. In pointing out the relative infrequency of the need to make choices, Clive Staples Lewis' seems to have understood how the making of them now reduces the need for them in the future. Lewis believed the regularity of nature is required for the making of undetermined choices that directly or indirectly cause events in the material world. Lewis concluded that our thinking (...) produces material events that are miraculous in the sense that they would not have occurred had nature proceeded on her own. He also concluded that someone who grasps what the topic of miracles is really about understands that there is nothing per se problematic with divine miracles. Finally, the chapter sets forth an important naturalistic argument against libertarian freedom and explains how Lewis would have responded to it. (shrink)

Although'Otherness' is an extremely common phenomenon in every society, related research is still at its beginnings.'Otherness' in the Middle Ages is a versatile and complex theme that covers a great number of different aspects, facets, and approaches: from non-human monsters and cultural strangers from remote places up to foreigners from another country or another town; it can refer to ethnic, cultural, political, social, sexual, or religious'Otherness', inside or outside one's own community. In any case, however,'Otherness' is a subjective phenomenon depending (...) on personal views and ascriptions, an issue of'imagination' and experience rather than'reality'. There is neither one single model of alterity nor is'Otherness' a stable phenomenon, but it changes over time and according to the cultural context. All this calls for methodological reflection and needs thorough investigation.00The methodological introduction and the 18 contributions of this volume demonstrate the great diversity of the theme and its different manifestations and perspectives. They tackle the problem from distinct angles and disciplines (history, art history, archaeology, literary history, and philology) in a wide chronological and thematic frame, using different methodological approaches, dealing with different areas (from Northern and Southern Europe to Byzantium and India), perspectives (including law, social order, the past, a sea), and diverse kinds of sources. They examine all kinds of'Otherness' mentioned above, highlight demarcation and rejection, aversion or acceptance, assimilation and integration, thus relativizing a strict dichotomy between'the Self' and'the Other' or between inside and outside. This volume is so far the most comprehensive attempt to tackle the huge problem of'Otherness' in the Middle Ages. (shrink)

This chapter discusses Clive Staples Lewis's views about the purpose of life. Lewis himself believed that nature does not have its own purposes. Instead, he thought God created the natural world, and the human beings which inhabit it, for a purpose. Lewis believed the purpose of life is that we experience a happiness that he variably described as eternal, infinite, complete, or perfect. The experience of this happiness is the life of the blessed. Lewis thought happiness is experiencing pleasure, where (...) experiencing pleasure is the purpose for which God created us. A hedonist about happiness is someone who believes not only that pleasure is intrinsically good but also holds that pain is intrinsically evil. To say that the experience of pain is intrinsically evil is to say that pain is evil and does not derive its evilness from its relationship to anything else. (shrink)

Knowledge of eukaryotic life cycles and associated genome dynamics stems largely from research on animals, plants, and a small number of “model” (i.e., easily cultivable) lineages. This skewed sampling results in an underappreciation of the variability among the many microeukaryotic lineages, which represent the bulk of eukaryotic biodiversity. The range of complex nuclear transformations that exists within lineages of microbial eukaryotes challenges the textbook understanding of genome and nuclear cycles. Here, we look in‐depth at Foraminifera, an ancient (∼600 million‐year‐old) lineage (...) widely studied as proxies in paleoceanography and environmental biomonitoring. We demonstrate that Foraminifera challenge the “rules” of life cycles developed largely from studies of plants and animals. To this end, we synthesize data on foraminiferal life cycles, focusing on extensive endoreplication within individuals (i.e., single cells), the unusual nuclear process calledZerfall, and the separation of germline and somatic function into distinct nuclei (i.e., heterokaryosis). These processes highlight complexities within lineages and expand our understanding of the dynamics of eukaryotic genomes. (shrink)