In most areas of medicine, the physician's primary task is to diagnose the patient's presenting problem by correctly identifying the underlying pathology causing that problem. Diagnoses are established through a process of correlating the information obtained from an interview with the patient about his history of illness and circumstances, with additional evidence of the underlying disease derived from physical examination findings and/or the results of laboratory investigations and diagnostic imaging. In contemporary health care, various movements that call for a shift (...) in clinical care away from underlying disease pathology toward understanding people and their experience of disease are receiving growing... (shrink)

L'importance que les défenseurs du Research Domain Criteria (RDoC) accordent aux circuits du cerveau dans la compréhension des désordres mentaux a conduit certains chercheurs à suspecter qu'on avait affaire à un programme de recherche foncièrement réductionniste. Puisque le RDoC devrait éventuellement affecter la psychiatrie clinique, on a craint qu'elle ne se transforme en une science neuro-comportementale appliquée sans tenir compte de l'esprit (mindless). Cet article montre en quoi le projet du RDoC s'éloigne du réductionnisme classique et comment il en évite (...) les écueils. Pour cette raison, du moins en principe, le RDoC pourrait enrichir plutôt qu'appauvrir la psychiatrie clinique. Pour conclure, les effets néfastes produits par le réductionnisme de façade des défenseurs du RDoC seront soulignés. (shrink)

Scientific realism driven by inference to the best explanation (IBE) takes empirically confirmed objects to exist, independent, pace empiricism, of whether those objects are observable or not. This kind of realism, it has been claimed, does not need probabilistic reasoning to justify the claim that these objects exist. But I show that there are scientific contexts in which a non-probabilistic IBE-driven realism leads to a puzzle. Since IBE can be applied in scientific contexts in which empirical confirmation has not yet (...) been reached, realists will in these contexts be committed to the existence of empirically unconfirmed objects. As a consequence of such commitments, because they lack probabilistic features, the possible empirical confirmation of those objects is epistemically redundant with respect to realism. (shrink)

Although it is argued that social justice is a core concern for the discipline, nursing has not generally played a leadership role in the responses to many of the greatest social problems of our time. These include the accelerated rate of climate change, pandemic threats, systemic racism, growing health and social inequities, and the regulation of new technologies to ensure an equitable future ‘for all.’ In nursing codes of ethics, administration, education, policies, and practice, social justice is often claimed to (...) be a core value, yet it is rarely contextualized by philosophical or theoretical underpinnings. It appears that nurses’ commitment to social justice may stem more from a penchant for ‘doing good’ than an attempt to explore, understand, and enact what is meant by social justice from an ontological, epistemological, and methodological perspective. We contend that the dominance of a human science perspective in nursing contributes to a narrow definition of health and relegates many issues central to social justice to the margins of nurses’ care. In this article, we explore how the focus on ‘the human’ in the human science perspective may not only be limiting the capacity of nurses to develop strategies to adequately address social injustice, but in some instances, direct nurses to contribute to their very reproduction. We suggest that a critical interrogation of this human‐centric hegemony can identify avenues of rupture and introduce posthumanism as an additional philosophical perspective for consideration to help bridge the human‐social divide. (shrink)

In this collection of newly commissioned essays, the contributors present a variety of approaches to it, engaging with historical and empirical aspects of the subject as well as contemporary philosophical work.

By examining an exemplar sample of mental health nursing educational policies and related legislation, in this article, we trace the discursive production of madness as an “othered” identity category. We engage in a critical discourse analysis of mental health nursing education in Canada, drawing on provincial and federal policies and legislation as the main sources of data. Theoretically framed by critical posthumanism and mad studies, this article outlines how the mad subjectivity becomes decontextualized out of its identity‐based understanding and recontextualized (...) as an inferior category of “the human,” circulating within discourses of pedagogy, economics, law, and psychiatry. The article maps the intertextual nexus of the discourse of mental health nursing education, making visible the complex, the arbitrary, and the sometimes‐contradictory nature of the discipline's grappling with identity‐based mental health concepts. We close with several implications for nursing policy, education, and practice. (shrink)

I explore the process of changes in the observability of entities and objects in science and how such changes impact two key issues in the scientific realism debate: the claim that predictively successful elements of past science are retained in current scientific theories, and the inductive defense of a specific version of inference to the best explanation with respect to unobservables. I provide a case-study of the discovery of radium by Marie Curie in order to show that the observability of (...) some entities can change and that such changes are relevant for arguments seeking to establish the reliability of success-to-truth inferences with respect to unobservables. (shrink)

In recent years, the hope to confirm the existence of dark matter by experimentally detecting it has diminished significantly. After more than 30 years of experimental searches, many of the most promising candidates have since been ruled out, leaving the epistemic and scientific condition of dark matter in a state of suspension. In efforts to improve the epistemic justification for the dark-matter hypothesis, physicists have turned to philosophical arguments and historical narratives. In this paper, I explicate two such strategies -- (...) explanatory unification and historical continuity -- applied in the context of dark matter. I argue that greater care and attention should be invested in the explanatory arguments to increase their strength, and that a survey of primary historical sources in astronomy renders the historical evidence for the continuity of dark matter substantially weaker. The quality and rigor of the philosophical and historical arguments which physicists are constructing could be substantially improved by increasing interdisciplinary practices. (shrink)

I argue that it is rational for a person to believe the conjunction of her beliefs. This involves responding to the Lottery and Preface Paradoxes. In addition, I suggest that in normal circumstances, what it is to believe a conjunction just is to believe its conjuncts.

The main purpose of this paper is to refute the metaphysicians ‘methodological continuation’ argument supporting epistemic realism in metaphysics. This argument aims to show that scientific realists have to accept that metaphysics is as rationally justified as science given that they both employ inference to the best explanation, i.e. that metaphysics and science are methodologically continuous. I argue that the reasons given by scientific realists as to why inference to the best explanation is reliable in science do not constitute a (...) reason to believe that it is reliable in metaphysics. The justification of IBE in science and the justification of IBE in metaphysics are two distinct issues with only superficial similarities, and one cannot rely on one for the other. This becomes especially clear when one analyses the debate about the legitimacy of IBE that has taken place between realists and empiricists. The metaphysician seeking to piggyback on the realist defense of IBE in science by the methodological continuation argument presupposes that the defense is straightforwardly applicable to metaphysics. I will argue that it is, in fact, not. The favoured defenses of IBE in scientific realism make extensive use of empirical considerations, predictive power and inductive evidence, all of which are paradigmatically absent in the metaphysical context. Furthermore, I argue that the metaphysician, even if the realist would concede to the methodological continuation argument, fails to offer any agreed upon conclusions resulting from its application in metaphysics. As a result, the scientific realist is not committed to believing that there is metaphysical knowledge. (shrink)

You care about what others believe about you. What others believe about you determines whether you have a good reputation, whether you have the respect of your peers, and whether your friends genuinely like you. Your caring about others’ beliefs makes sense, because others’ beliefs bear directly upon your level of well-being. Your beliefs can influence others’ well-being, as much as their beliefs can influence yours. How your beliefs influence another’s well-being is a different matter from whether your beliefs are (...) supported by the evidence. Sometimes you can benefit another person by regulating your beliefs in response to considerations of her well-being, not of the evidence. Usually, you do not have strong reasons to regulate your beliefs in response to considerations of the interests of others. But it can be different when the person in question is your friend. Within some perfectly good friendships, the support that each friend provides for the other extends as far as their being willing to regulate their beliefs with the goal of benefiting the other, even if that makes it less likely that their beliefs will be supported by the evidence. Within our friendships, we then have reasons for belief that do not arise directly from, and sometimes compete with, reasons provided by evidence. This claim conflicts with the widespread Aristotelian view that good friendship is oriented to virtue. But it fits with a more plausible view about friendship, on which the function of friendship is to help us cope with the fact that we are not fully virtuous, and to serve needs that we have because we are not fully virtuous. (shrink)

It has been suggested that iconic graphical signs evolve into symbolic graphical signs through repeated usage. This article reports a series of interactive graphical communication experiments using a ‘pictionary’ task to establish the conditions under which the evolution might occur. Experiment 1 rules out a simple repetition based account in favor of an account that requires feedback and interaction between communicators. Experiment 2 shows how the degree of interaction affects the evolution of signs according to a process of grounding. Experiment (...) 3 confirms the prediction that those not involved directly in the interaction have trouble interpreting the graphical signs produced in Experiment 1. On the basis of these results, this article argues that icons evolve into symbols as a consequence of the systematic shift in the locus of information from the sign to the users' memory of the sign's usage supported by an interactive grounding process. (shrink)

According to the Everett interpretation, branching structure and ratios of norms of branch amplitudes are the objective correlates of chance events and chances; that is, 'chance' and 'chancing', like 'red' and 'colour', pick out objective features of reality, albeit not what they seemed. Once properly identified, questions about how and in what sense chances can be observed can be treated as straightforward dynamical questions. On that basis, given the unitary dynamics of quantum theory, it follows that relative and never absolute (...) chances can be observed; that only on repetition of a large numbers of similar trials can relative probabilities be measured; and so on. The epistemology of objective chances can in this way be worked out from the dynamics. its curious features are thus explained. But one aspect of chance set-ups seems to resist this subsuming of chancing to branching: how is it that chance involves uncertainty? And if that is not possible, on Everettian lines, then the whole project is doomed. I argue that in fact there is no difficulty in making sense of uncertainty in the face of branching. Contrary to initial impressions, the unitary formalism is consistent with a well-defined notion of self-locating uncertainty. It is also consistent without: the mathematics under-determines the metaphysics in these respects. (shrink)

Cancer is a singular cellular state, the emergence of which destabilises the homeostasis reached through the evolution to multicellularity. We present the idea that the onset of the cellular disobedience to the metazoan functional and structural architecture, known as the cancer phenotype, is triggered by changes in the cell's external environment that occur with ageing: what ensues is a breach of the social contract of multicellular life characteristic of metazoans. By integrating old ideas with new evidence, we propose that with (...) ageing the environmental information that maintains a multicellular organisation is eroded, rewiring internal processes of the cell, and resulting in an internal shift towards an ancestral condition resulting in the pseudo‐multicellular cancer phenotype. Once that phenotype emerges, a new local social contract is built, different from the homeostatic one, leading to tumour formation and the foundation of a novel local ecosystem. (shrink)

Beginning with a critical examination of the humanist assumptions of critical ethnography, this article interrogates and surfaces problems with the ontological and epistemological orientations of this research methodology. In drawing on exemplar empirical data from an arts‐based project, the article demonstrates the limitations in the humanist‐based qualitative research approach and advances a postdualist, postrepresentationalist direction for critical ethnography called entangled ethnography. Using data from a larger study that examined the perspectives of racialized mad artists, what is demonstrated in this inquiry (...) is that the entanglement of bodies, objects, and meaning‐making practices is central to working with the ontologically excluded, such as those who find themselves in various states of disembodiment and/or corporeal and psychic distribution. We propose the redevelopment of critical ethnography, extended by entanglement theory (a critical posthuman theory), and suggest that for it to be an inclusive methodology, critical ethnography must be conceptualized as in the process of becoming and always in regeneration, open to critique, extension, and redevelopment. (shrink)

The Prologue offers an overview of the Reformation of method from Augustine of Hippo through to the Ramist movement, providing an orientation to the rest of the book. It highlights and explains an important nexus of Realism, exemplarism and illumination fundamental to Ramism. Beginning with Augustine it shows how these themes coalesced into a distinctive Christian philosophy taken up and refined by Franciscans such as Bonaventure of Bagnoregio and John Duns Scotus, as well as by Ramon Lull, the Franciscan-inspired encyclopaedist. (...) It traces the continuation of this methodological impulse into the Platonism and Christian humanism of the Renaissance, highlighting especially the topical and Realist (Scotistic) reform of logic pioneered by Lorenzo Valla and Rudolph Agricola. It concludes by showing the reception of this topical and biblical reform in Philipp Melanchthon and the movement of Reformed scholasticism, revealing Reformed Scotism and Christian philosophy as important preconditions for Ramism. (shrink)

In this paper I discuss the shapelessnesss hypothesis, which is often referred to and relied on by certain sorts of ethical and evaluative cognitivist, and which they use primarily in arguing against a certain, influential form of noncognitivism. I aim to (i) set out exactly what the hypothesis is; (ii) show that its original and traditional use is left wanting; and (iii) show that there is some rehabilitation on offer that might have a chance of convincing neutrals.

Causal queries about singular cases, which inquire whether specific events were causally connected, are prevalent in daily life and important in professional disciplines such as the law, medicine, or engineering. Because causal links cannot be directly observed, singular causation judgments require an assessment of whether a co‐occurrence of two events c and e was causal or simply coincidental. How can this decision be made? Building on previous work by Cheng and Novick (2005) and Stephan and Waldmann (2018), we propose a (...) computational model that combines information about the causal strengths of the potential causes with information about their temporal relations to derive answers to singular causation queries. The relative causal strengths of the potential cause factors are relevant because weak causes are more likely to fail to generate effects than strong causes. But even a strong cause factor does not necessarily need to be causal in a singular case because it could have been preempted by an alternative cause. We here show how information about causal strength and about two different temporal parameters, the potential causes' onset times and their causal latencies, can be formalized and integrated into a computational account of singular causation. Four experiments are presented in which we tested the validity of the model. The results showed that people integrate the different types of information as predicted by the new model. (shrink)

Little is known about research misconduct within industry and how it compares to universities, even though a lot of biomedical research is performed by–or in collaboration with–commercial entities. Therefore, we sent an e-mail invitation to participate in an anonymous computer-based survey to all university researchers having received a biomedical research grant or scholarship from one of the two national academic research funders of Belgium between 2010 and 2014, and to researchers working in large biomedical companies or spin-offs in Belgium. The (...) validated survey included questions about various types of research misconduct committed by respondents themselves and observed among their colleagues in the last three years. Prevalences of misconduct were compared between university and industry respondents using binary logistic regression models, with adjustments for relevant personal characteristics, and with significance being accepted for p < 0.01. The survey was sent to 1766 people within universities and an estimated 255 people from industry. Response rates were 43 and 48%, and usable information was available for 617 and 100 respondents, respectively. In general, research misconduct was less likely to be reported by industry respondents compared to university respondents. Significant differences were apparent for one admitted action and three observed actions, always with lower prevalences for industry compared to universities, except for plagiarism. This survey, based on anonymous self-report, shows that research misconduct occurs to a substantial degree among biomedical researchers from both industry and universities. (shrink)

In this article I compare Ryle's notion of a thick description with Williams' notion of a thick concept so as to illuminate our understanding of both. In doing so I suggest lines of thought that show us that the notion of 'evaluation' in play in many people's writings should be broadened. Doing so will help to lessen the credibility of separationist notions of thick concepts.

Book synopsis: Simon May presents a fresh and wide-ranging critique of Nietzsche's famous attack on traditional morality, and of his controversial ethics of 'life-enhancement'. He reveals Nietzsche as both revolutionary and conservative–as one who repudiates traditional 'moral' conceptions of God, guilt, asceticism, pity, and truthfulness, and yet retains a demanding ethics of discipline, conscience, 'self-creation', generosity, and honesty. In particular, May shows how Nietzsche rejects truthfulness as an unconditional value and yet celebrates it as one of his own highest (...) values, whose worth is determined by who is pursuing it, for what end, and when in their lives. May is strongly critical of various aspects of Nietzsche's thought–his self-defeating conception of justice, his assumption that 'life-enhancement' necessarily demands world-affirmation, his ambition to de-deify the world, and the impossible and undesirable autonomy of the Übermensch. But Nietzsche is shown to offer modernity key elements of a coherent ethic, and to provide moral philosophy with important tools for reassessing some of its most cherished values and concepts. May's book will be illuminating not just for scholars and students of Nietzsche, in philosophy, literature, and history of ideas, but for anyone interested in current debates about ethics and modernity. (shrink)

We examined the dilemmas posed by the involvement of expert witnesses in court cases and the institutional constraints on the ethics of expert testimony. The causes for the incorporation of bad science into legal decisions, potential solutions to this dilemma, and the limitations of these solutions are considered. We concluded that law, science, and experts must respond to the problems posed by expert witnessing.

Paul Ricoeur and Marya Schechtman express grave doubts about the acceptability and informativeness of the thought-experiments employed by analytic philosophers (notably Derek Parfit) in the debate about personal identity, and for what appear to be related reasons. I consider their reasoning and argue that their reasons fail to justify their doubts. I go on to argue that, from this discussion of possible problems concerning select thought-experiments, something positive can be learned about personal identity.

Computational modeling is now ubiquitous in psychology, and researchers who are not modelers may find it increasingly difficult to follow the theoretical developments in their field. This book presents an integrated framework for the development and application of models in psychology and related disciplines. Researchers and students are given the knowledge and tools to interpret models published in their area, as well as to develop, fit, and test their own models. Both the development of models and key features of any (...) model are covered, as are the applications of models in a variety of domains across the behavioural sciences. A number of chapters are devoted to fitting models using maximum likelihood and Bayesian estimation, including fitting hierarchical and mixture models. Model comparison is described as a core philosophy of scientific inference, and the use of models to understand theories and advance scientific discourse is explained. (shrink)

I argue that mass produced artifacts are ontologically distinctive. If we think of the making of an artifact as the imposition of a creative intention on to some matter, usually through intentional manipulation of the matter, then in the case of mass production, one could say that there is not enough mind to go around! Batches of mass produced objects will have a distinctive essence, lying in the creative act by which they are made, but within a batch, the objects (...) will be distinct from each other, but not essentially distinct. (shrink)

In his recent Immaterialism, Graham Harman develops a theory of social objects based on his object-oriented ontology. Whereas some of the more mainstream theories in the humanities would dissolve such objects into their material constituents or their various effects on others, object-oriented social theory theorizes them as inert, resilient entities with a private reality that exceeds their components and actions. Harman’s theory focuses on what social entities are qua objects, and consequently says little about their specificity as social objects. A (...) more complete social theory would also outline how human existence is to be understood in relation to a social world comprised of discrete and inert entities, as opposed to, for example, far more continuous material fields or networks of associations. We argue that an unexpected yet solid candidate for such an extension of object-oriented social theory already exists in Jean-Paul Sartre’s theory of practico-inert being and group formation. We first outline Harman’s and Sartre’s respective ontologies of social objects, and then discuss how their many complementarities make the latter a suitable extension of the former. (shrink)

This paper examines a particularly egregious example of a NIMBY claim and considers three proposals for explaining what about that claim might be ethically problematic: The NIMBY claimant is being selfish or self-serving; The NIMBY claim cannot be morally justified, because respecting everyone's NIMBY claims leaves communities worse off; and if policymakers were to defer to people's NIMBY claims, they would end up perpetuating environmental injustices. We argue that these proposals fail to explain why there is anything wrong with the (...) NIMBY claim per se. (shrink)

Ethical decision-making is inherent to the research ethics committee deliberation process. While ethical codes, regulations, and research standards are indispensable in guiding this process,...

In recent times, realism in economic methodology has increasingly gained importance. Uskali Mäki and Tony Lawson are the best-known realists within the discipline and even though their approaches are fundamentally different, both provide pragmatic defences of realism by claiming anti-realism to be the reason for the low quality of economic models. My paper will show that a pragmatic defence of realism is untenable and furthermore, I will show that for both Mäki's and Lawson's normative ideas there is no need for (...) realism. (shrink)

The syntagmatic paradigmatic model is a distributed, memory‐based account of verbal processing. Built on a Bayesian interpretation of string edit theory, it characterizes the control of verbal cognition as the retrieval of sets of syntagmatic and paradigmatic constraints from sequential and relational long‐term memory and the resolution of these constraints in working memory. Lexical information is extracted directly from text using a version of the expectation maximization algorithm. In this article, the model is described and then illustrated on a number (...) of phenomena, including sentence processing, semantic categorization and rating, short‐term serial recall, and analogical and logical inference. Subsequently, the model is used to answer questions about a corpus of tennis news articles taken from the Internet. The model's success demonstrates that it is possible to extract propositional information from naturally occurring text without employing a grammar, defining a set of heuristics, or specifying a priori a set of semantic roles. (shrink)

Grammatical asymmetries in possessive constructions are overtly coded in about 18% of the world’s languages according to the World Atlas of Language Structures What primarily motivates these grammatical asymmetries is controversial and has been at the crux of the “iconicity vs. frequency” debate This paper contributes to this debate by focusing on the grammatical asymmetries of Paamese possessive constructions, and looking for the primary motivating factor in their multidimensional experiential context. After a careful account of four experiential dimensions of distance, (...) the degrees of experiential distance are shown to systematically correspond to the degrees of formal distance of the possessive constructions used to refer to these experiences. Relevant anthropological and linguistic data concerning Paamese is used to explore whether this correspondence between language and experience is primarily motivated by iconicity or economy. I argue that diagrammatic iconicity is the primary motivating factor for the grammatical asymmetries in Paamese possessive constructions, and that economy can account for some, but not all cases. I also show that economy and iconicity can collaborate in motivating some cases, and thus do not necessarily need to be opposed. (shrink)

The 85th birthday of Zygmunt Bauman in November 2010 presented the occasion for TCS to publish a special section of commissioned commentary pieces on a number of central themes in his work. The section, edited and introduced by editorial board member Roy Boyne, featured articles by Martin Jay, John Milbank and Julia Hell, and concentrated respectively upon the themes of modernity, the role of the intellectual, and the gaze of/at the other, highlighting the dependence on metaphor and the significance of (...) ‘looking’ in his writing. This interview takes that special section as its starting point, and asks Bauman to respond to some of the claims and suggestions made in those articles. In doing so, he argues for the continuing salience of the ‘liquid modernity’ concept for understanding the ‘purpose behind the effort’, and explains in detail his view of the intellectual (and, specifically, the sociologist) and the role such an intellectual should play in the context of liquid modernity. (shrink)

What is the meaning of general covariance? We learn something about it from the hole argument, due originally to Einstein. In his search for a theory of gravity, he noted that if the equations of motion are covariant under arbitrary coordinate transformations, then particle coordinates at a given time can be varied arbitrarily - they are underdetermined - even if their values at all earlier times are held fixed. It is the same for the values of fields. The argument can (...) also be made out in terms of transformations acting on the points of the manifold, rather than on the coordinates assigned to the points. So the equations of motion do not fix the particle positions, or the values of fields at manifold points, or particle coordinates, or fields as functions of the coordinates, even when they are specified at all earlier times. It is surely the business of physics to predict these sorts of quantities, given their values at earlier times. The principle of general covariance therefore seems untenable. (shrink)