Dr Sydney Brenner has played a major, and unique, role in biology during the past 40 years. His contributions have ranged from key work on the structure of the genetic code and the existence of mRNA through the development of Caenorhabditis elegans as a key model system in developmental biology to genomic analysis and function in vertebrates. BioEssays went to interview Dr Brenner at his home in the cathedral city of Ely, England, on the significance of the genome (...) projects for human biology, in particular, and for biology, in general. (shrink)

Quelle conception de la science proposer aujourd'hui? Les grandes doctrines du XXe siècle se sont heurtées successivement à des difficultés, que ce soit le positivisme du Cercle de Vienne ou le rationalisme critique de Popper. Même la perspective historique inspirée par Bachelard et par Kuhn a donné lieu à des versions disparates. Pourtant, toutes ces tentatives partent d'un même constat : l'échec de la vision classique de la science et la nécessité d'un nouveau discours. On peut en retracer l'histoire. Face (...) à la pluralité des hypothèses possibles au sujet de l'espace, du temps et de la matière, Poincaré pose l'existence de conventions, ou mieux de libres décisions, au cœur de la science. Ainsi, dès la fin du XIXe siècle, il coupe court aux projets traditionnels de fondation : ni le synthétique a priori de Kant, ni les faits généraux de Comte ne sauraient expliquer la nature de l'activité scientifique. C'est la naissance d'un mouvement d'idées, le conventionnalisme, quia eu un impact décisif sur la philosophie viennoise et, à travers elle, sur la philosophie mondiale. Voilà un fil conducteur pour évaluer un siècle de débats. Que signifie donc libre décision en matière scientifique? On affirme la dimension historique irréductible de notre savoir ; on reconnaît la créativité et la responsabilité inhérentes à la science en tant qu'aventure humaine. (shrink)

All organizations have ethics programs which consist of both explicit and implicit parts. This paper defines corporate ethics programs and identifies a number of their components. Corporate ethics programs'' structural and behavioral dimensions are proposed which may allow further examination of such program components and their impacts. Finally, fifteen propositions are suggested which describe the influence of founder values, competitive pressures, leadership, and organizational problems on corporate ethics programs and the manageability of such programs.

'Gender Hurts' examines the wider social and political context and implications of the phenomenon of transgenderism. Jeffreys and Gottschalk propose that gender in western culture is socially constructed as the basis of male domination and that the concept of gender has the potential to hurt many.

Nearly 70 years after the dawn of the genetic age, biotechnology, scientists proclaim, is poised to rewrite the book of life. Yet, how far can science go in making sense of what "life" means to human beings and societies? This book looks at flash points in law, politics, ethics, and culture to argue that the claims of rewriting life are overblown.

From Hippocrates to paternalism to autonomy : the new hegemony -- From autonomy to consent -- Consent, autonomy, and the law -- Autonomy at the end of life -- Autonomy and pregnancy -- Autonomy and genetic information -- Autonomy and organ transplantation -- Autonomy, consent, and the law.

I present new counterexamples to the asymmetry of grounding: we have prima facie reason to think that some conditional probabilities partially ground their inverse conditional probabilities, and vice versa. These new counterexamples may require that we reject the asymmetry of grounding, or alternatively may require that we reject one or more of the assumptions which enable the counterexamples. Either way, by reflecting on these purported counterexamples to grounding asymmetry we learn something important, either about the formal properties of grounding, or (...) about the nature of probability. (shrink)

This collection of essays by Sheila Jasanoff explores how democratic governments construct public reason, that is, the forms of evidence and argument used in making state decisions accountable to citizens.

1. The field of genetics has seen a huge increase in advancements over the past decade. Diseases that were once considered to have no treatment options yielding dismal outcomes now have quick and e...

On souligne couramment la pluralité des sciences et la diversité de ses méthodes. Devons-nous pour autant nous résigner à cette situation de fait ? Il s’agit d’interroger, à partir de l’oeuvre meyersonienne, la tension entre la spécialisation sans cesse accrue et la nécessaire coordination des faits. Cette oeuvre fournit l’exemple d’un projet encyclopédique souple, dans lequel l’épistémologie permet de transcender les cloisonnements disciplinaires.Today, the burden of proof appears to rest on those who defend the unity of the sciences. Yet, in (...) scientific research, concepts and methods are transposed from one field to another, and interdisciplinary approaches flourish. Meyerson provides the opportunity to take up this issue once again. His work offers the example of a moderate unitary conception of science. It is encyclopedic but not reductionist. (shrink)

This chapter contains sections titled: Point of Departure Kant's Concept of Dignity The Dignity of the Lived‐Body Bodily Authenticity.

Some facts ground other facts. Some fact is fundamental iff there are no other facts which partially or fully ground that fact. According to metaphysical foundationalism, every non-fundamental fact is fully grounded by some fundamental fact(s). In this paper I examine and defend some neglected considerations which might be made in favor of metaphysical foundationalism. Building off of work by Ross Cameron, I suggest that foundationalist theories are more unified than, and so in one important respect simpler than, non-foundationalist theories, (...) insofar as foundationalist theories allow us to derive all non-fundamental facts from some fundamental fact(s). Non-foundationalist theories can enjoy a similar sort of theoretical unification only by taking on objectionable metaphysical laws. (shrink)

In the Western philosophical tradition logical investigation and philosophical advance have been inextricably linked, each having stimulated and shaped the other. In Logic and Philosophy William H. Brenner examines a broad range of logical concepts and methods as they relate to the larger context of philosophical investigation and thus bring to light the philosophical depth of logic and its relevance to philosophy in general.

Following the standard view, scientific theories are formal systems, which receive empirical content by way of certain correspondence rules. The task of philosophy of science is then to make explicit the structure of such systems. In contrast to this view, one can point to the French tradition in philosophy of science. What characterizes this tradition is recourse to historical study, which has evolved from an attempt to bridge the fields of philosophy of science and history of science by a closer (...) integration of conceptual and historical methods. My aim in this paper is to explore the emergence of historical epistemology in France and its later revival at an international level. Attention is directed at the presuppositions and motivations underlying such an approach. (shrink)

The power of technology? -- Risk and responsibility? -- The ethical anatomy of disasters? -- Remaking nature? -- Tinkering with humans? -- Information's wild frontiers? -- Whose knowledge, whose property? -- Reclaiming the future? -- The ethics of invention?

In the past twenty years, the field of science and technology studies (S&TS) has made considerable progress toward illuminating the relationship between scientific knowledge and political power. These insights have not yet been synthesized or presented in a form that systematically highlights the connections between S&TS and other social sciences. This timely collection of essays by some of the leading scholars in the field attempts to fill that gap. The book develops the theme of "co-production", showing how scientific knowledge both (...) embeds and is embedded in social identities, institutions, representations and discourses. Accordingly, the authors argue, ways of knowing the world are inseparably linked to the ways in which people seek to organize and control it. Through studies of emerging knowledges, research practices and political institutions, the authors demonstrate that the idiom of co-production importantly extends the vocabulary of the traditional social sciences, offering fresh analytic perspectiveson the nexus of science, power and culture. (shrink)

Dreamscapes of Modernity offers the first book-length treatment of sociotechnical imaginaries, a concept originated by Sheila Jasanoff and developed in close collaboration with Sang-Hyun Kim to describe how visions of scientific and technological progress carry with them implicit ideas about public purposes, collective futures, and the common good. The book presents a mix of case studies—including nuclear power in Austria, Chinese rice biotechnology, Korean stem cell research, the Indonesian Internet, US bioethics, global health, and more—to illustrate how the concept (...) of sociotechnical imaginaries can lead to more sophisticated understandings of the national and transnational politics of science and technology. A theoretical introduction sets the stage for the contributors’ wide-ranging analyses, and a conclusion gathers and synthesizes their collective findings. The book marks a major theoretical advance for a concept that has been rapidly taken up across the social sciences and promises to become central to scholarship in science and technology studies. (shrink)

Scholars in science and technology studies (STS) have recently been called upon to advise governments on the design of procedures for public engagement. Any such instrumental function should be carried out consistently with STS’s interpretive and normative obligations as a social science discipline. This article illustrates how such threefold integration can be achieved by reviewing current US participatory politics against a 70-year backdrop of tacit constitutional developments in governing science and technology. Two broad cycles of constitutional adjustment are discerned: the (...) first enlarging the scope of state action as well as public participation, with liberalized rules of access and sympathetic judicial review; the second cutting back on the role of the state, fostering the rise of an academic-industrial complex for technology transfer, and privatizing value debates through increasing delegation to professional ethicists. New rules for public engagement in the United Sates should take account of these historical developments and seek to counteract some of the anti-democratic tendencies observable in recent decades. (shrink)

Individual, family, economic, and other forms of people suffering impact organizations. Suffering in the workplace is probably a more common occurrence than expected in everyday life, and opposite to health and employee wellbeing. According to the World Health Organization, 300 million people worldwide struggle with depression and close to 800.000 people die due to suicide every year. The European Survey on Working Conditions in the European Union gathers the most varied aspects of working conditions, such as the duration of the (...) working day, relationships between collaborators in organizations, or healthy work habits. Among the results of that survey it is noteworthy that almost half of the close to twenty-two thousand workers surveyed in the 27 member countries stated that they felt uneasiness due to the conditions of their work. (shrink)

O pós-guerra fria propiciou a instauração da Nova Ordem Mundial onde o mundo passa a ser multipolar, verificando-se o surgimento de novas ameaças devido ao enfraquecimento das instituições, promovido pelas crescentes desigualdades sociais, dependência dos Países periféricos em relação aos centrais aliada a revolução tecnológica e globalização. Este artigo tem como objectivo abordar o surgimento e causas de novas ameaças e possíveis soluções. O estudo foi baseado nas teorias neorrealista, construtivista e teoria da Escola de Copenhague; e usado os métodos (...) histórico-dedutivo e comparativo, com técnicas de revisão bibliográfica e fontes secundárias. A conclusão indica que a solução para as novas ameaças passa pela cooperação entre os Estados na elaboração de políticas globais para a segurança e paz, criação de serviços de inteligência constituído por vários Países, promoção de Não Proliferação de Armas Nucleares, elaboração de estratégias para combater as possíveis fontes estatais do seu financiamento para evitar uma guerra. Palavras-Chaves: Actores; Estados; Globalização; Novas Ameaças e Tratado. (shrink)

Pendant un demi-siècle, la méthode appropriée en philosophie des sciences dans la tradition continentale était l'étude historique ; dans la tradition anglosaxonne, l'analyse logique. Ce clivage au sein du discours philosophique s'est grandement estompé de nos jours. D'une part, Kuhn a défendu la pertinence philosophique de l'histoire des sciences. D'autre part, Vuillemin et Gilles-Gaston Granger ont promu l'étude de la philosophie analytique et l'emploi de ses techniques logiques. Le rapprochement des deux traditions a pris encore une nouvelle tournure dans les (...) derniers textes de Feyerabend et dans les travaux de Ian Hacking. Celui-ci associe délibérément les instruments historiques de l'école française avec les procédés logiques de l'école nordaméricaine. Quelle est la signification de ce rapprochement ? Quels problèmes fait-il surgir ? Quelles directions de recherche ouvre-t-il ? Telles sont les questions que nous aborderons par le biais d'une étude comparée de certains développements récents de la philosophie des sciences en France et en Amérique du Nord. For over half a century the continental tradition favored a historical method in philosophy of science, while the Anglo-American tradition promoted a logical method. In recent years this contrast has tended to lessen. On the one hand, there has been a growing interest since the 1970s in France for the analytic tradition, due to the pioneering studies of Vuillemin and Gilles-Gaston Granger. On the other hand, Kuhn has brought out the philosophical relevance of history of science. This tendency takes a new turn in Feyerabend's final texts as well as in the works of Ian Hacking. The latter deliberately combines the historical instruments of the French school with the logical techniques of the North-American school. How to understand this evolution ? What directions of research does it open up ? I address these questions by way of a comparative study of some recent developments in philosophy of science both in France and North America. (shrink)

In 1903 Mach and Duhem, discovering one another’s writings, acknowledged the proximity of the philosophical views that they had been elaborating independently. A correspondence followed, which lasted several years. And in their ensuing publications both of these philosopher-scientists were careful to discuss their interlocutor’s claims. We have here ample matter for consideration. Mach and Duhem were to have an impact on the development of the Vienna Circle. Yet their conceptions are indeed different from those that followed. Characteristically, they drew on (...) history and psychology. They were interested in the genesis of concepts, the evolution of theories and the patterns of discovery. If rational reconstruction and logical analysis were admitted, these techniques were counter-balanced by historical study. In view of recent evolutions in philosophy of science — the growing importance of cognitive science, history of science, interdisciplinarity — it is worthwhile to return again to the beginning of the twentieth century. The aim of this paper is then to reexamine the relation between Duhem and Mach, in particular with regard to the methods whereby they sought to provide a philosophical reflection on science. (shrink)

Die Bezeichnung „alt“ hat sich zu einem Wertbegriff negativer Konnotation gewandelt, so dass er synonym für alle möglichen Defizienzen bzw. als Chiffre für Defizienz schlechthin steht. Alt zu sein ist nun nicht länger eine Sache der Jahre, sondern von (verloren gegangenen) Qualitäten. Positiv ist daran, dass (fast wieder alles) möglich ist, negativ ist, dass gerade deshalb auch (fast) wieder alles ermöglicht werden muss. Denn der Alte ist selber schuld und will er es nicht bleiben, muss er etwas daran ändern. Die (...) Krankschreibung des Alters ruft seine Behandlung hervor, was nichts anders bedeutet als dass das Alter, das als Krankheit begriffen wird, kuriert werden muss, wobei die Kur nicht in seiner Heilung, sondern in seiner Überwindung, d.h. seiner Abschaffung besteht. Das Anti-Aging verfolgt eine radikale Abkehr vom Menschen, wie wir ihn kennen. Gerade am Alter lässt sich aber zeigen, dass der Mensch mit Mängeln leben kann, häufig trotz seiner Mängel glücklich wird und mit ihnen sogar seinen Frieden macht. (shrink)

Si l’oeuvre d’historien de la philosophie que Brunschvicg a élaborée est largement reconnue, ses efforts dans le champ de ce qu’il nommait philosophie scientifique soulèvent une certaine perplexité. Ce versant de son oeuvre aurait été éclipsé par Bachelard et sa philosophie du nouvel esprit scientifique. L’avènement de la philosophie analytique et sa réception en France auraient achevé de rejeter dans l’ombre la critique brunschvicgienne de la philosophie de la logique de Russell. Pourtant, Brunschvicg a oeuvré sans relâche à un rapprochement (...) entre philosophie et science. Il a entrepris un examen précis et approfondi des théories les plus récentes des mathématiques et de la physique. Or on constate aujourd’hui une exigence accrue en matière d’histoire et une multiplication des méthodes d’investigation. Le but de cet article est d’interroger à nouveaux frais la pensée épistémologique de Brunschvicg. (shrink)

In the original publication of this article, we have missed to include second affiliation of the corresponding author in the online published article. Now the same has been provided in this correction.

Volume 1. Der Weg ; Das Wissen ; Die Welt ; Die Zeit ; Die Neuschöpfung der Polis ; Die sokratische Methode : Àreté ist ein Wissen ; Nicht-Wissen und Nicht-Können -- Volume 2. Das Interesse am gelingenden Leben ; Erkenne und erzeuge dich selbst : Aùto-génesis und Eùdaimonía.

Los discursos de odio y las retóricas que estigmatizan, deshumanizan y demonizan al colectivo inmigrante son una palanca necesaria para la necropolítica. La permisividad en el discurso público a ideas y prejuicios contrarios a la inmigración es consustancial al formato necropolítico de gestión de las migraciones en la Unión Europea. Este trabajo, inspirado en las aportaciones de Achille Mbembe y Judith Butler, reflexiona sobre la configuración del sentimiento antinmigrante que, articulado a través de la violencia simbólica que atraviesa medios de (...) comunicación y redes sociales, repercute en la creciente vulnerabilidad que afecta a este colectivo. (shrink)

In calling for the transformation of military medical education and training, the 2005 Base Realignment and Closure Commission recommended relocating basic and specialty enlisted medical training to a single site to take advantage of economies of scale and the opportunity for joint training. As a result, a joint medical education and training campus (METC) has been established at Fort Sam Houston, Texas. Two of METC's primary long-term goals are to become a high-performing learning organization and to seek accreditation as a (...) community college. Such goals require a clear model of organizational improvement with well-defined metrics for measuring its performance and using research and evaluation to assess and improve that performance. Lessons learned from a review of practices at institutions with similar missions -- such as community colleges, corporate universities, the UK's Defence Medical Education and Training Agency, and other federal agencies, such as the Veterans Health Administration -- establish a clear need for an office of institutional research to help METC attain its organizational goals. They also provide useful recommendations regarding the METC office's structure, scope, and governance. (shrink)

_Explores the philosophical, literary, and psychoanalytic significance of film endings._ Editing has been called the language of cinema, and thus a film’s ending can be considered the final punctuation mark of this language, framing everything that came before and offering the key to both our interpretation and our enjoyment of a film. In _Cinematic Cuts_, scholars explore the philosophical, literary, and psychoanalytic significance of film endings, analyzing how film endings engage our fantasies of cheating death, finding true love, or determining (...) the meaning of life. They examine how endings offer various forms of enjoyment for the spectator, from the momentary fulfillment of desire in the happy ending to the pleasurable torment of an indeterminate ending. The contributors also consider how film endings open onto larger questions relating to endings in our time. They suggest how a film ending’s hidden counternarrative can be read as a political act, how our interpretation of a film ending parallels the end of a psychoanalytical session, how film endings reveal our anxieties and fears, and how cinema itself might end with the increasing intervention of digital technologies that reorient the spectator’s sense of temporality and closure. Films by Akira Kurosawa, Lars von Trier, Joon-Hwan Jang, Claire Denis, Christopher Nolan, Jane Campion, John Huston, and Spike Jonze, among others, are discussed. (shrink)

This chapter contains sections titled: An Introduction to Motherhood – Philosophy for Everyone Notes.

El presente artículo recoge la crítica de Adorno y Pasolini a la era abierta por Mayo del 68 y trata de trasladarla a nuestros días. El objetivo es trazar líneas de continuidad entre lo que los dos autores atisbaron en aquel movimiento y la actualidad. Con base en ello, se partirá de la denuncia de la “intolerancia” y el “dogmatismo” que tanto Adorno como Pasolini achacaron al movimiento; seguidamente, se recogerá la descripción de los dos autores de la época de (...) banalidad que, en su opinión, se abría ante el menosprecio del pensamiento reflexivo, la teoría y la cultura. Presentaremos la “lucha desde la teoría” de ambos autores y su posicionamiento como filósofos inorgánicos ante una época de activismo irreflexivo. Por último, esbozaremos el estado de la cuestión en la actualidad en el apartado Conclusiones. (shrink)