Basement membranes are thin sheets of extracellular proteins situated in close contact with cells at various locations in the body. They have a great influence on tissue compartmentalization and cellular phenotypes from early embryonic development onwards. The major constituents of all basement membranes are collagen IV and laminin, which both exist as multiple isoforms and each form a huge irregular network by self assembly. These networks are connected by nidogen, which also binds to several other components (proteoglycans, fibulins). Basement membranes (...) are connected to cells by several receptors of the integrin family, which bind preferentially to laminins and collagen IV, and via some lectin‐type interactions. The formation of basement membranes requires cooperation between different cell types since nidogen, for example, is usually synthesized by cells other than those exposed to the basement membranes. Thus many molecular interactions, of variable affinities, determine the final shape of basement membranes and their preferred subanatomical localization. (shrink)

Robert Rupert argues against the view that human cognitive processes comprise elements beyond the boundary of the organism, developing a systems-based conception in place of this extended view. He also argues for a conciliatory understanding of the relation between the computational approach to cognition and the embedded and embodied views.

A two-worlds view of Plato’s epistemology holds that the objects of the epistemic powers knowledge and belief cannot overlap. Whereas, an overlap view claims that they can. The two-worlds view has...

Buber’s distinction between the ‘I-It’ mode and the ‘I-Thou’ mode is seminal for dialogic education. While Buber introduces the idea of dialogic space, an idea which has proved useful for the analysis of dialogic education with technology, his account fails to engage adequately with the role of technology. This paper offers an introduction to the significance of the I-It/I-Thou duality of technology in relation with opening dialogic space. This is followed by a short schematic history of educational technology which reveals (...) the role technology plays, not only in opening dialogic space, but also in expanding dialogic space. The expansion of dialogic space is an expansion of what it means to be ‘us’ as dialogic engagement facilitates the incorporation, into our shared sense of identity, of aspects of reality that are initially experienced as alien or ‘other’. Augmenting Buber with an alternative understanding of dialogic space enables us to see how dialogue mediated by technology, as well as dialogue with monologised fragments of technology, can, through education, lead to an expansion of what it means to be human. (shrink)

Educational technology is controversial - some see it as essential to providing free global learning, others view it as a dangerous distraction that undermines good education. In both instances, most theories that have previously been applied to educational technology do not account for the distinctive nature and vast potential of technology. This book addresses this issue, exploring how education has been bound up with technology from the beginning, and recognising that educational aims have already been shaped by technologies. Offering a (...) 'dialogic' theory of educational technology, Rupert Wegerif and Louis Major respond to contemporary challenges to education within this book, including, but not limited to, climate change, misinformation on the internet and the impact of Artificial Intelligence (AI). Chapters introduce, discuss, and contextualise key theories and illustrate through case studies their uses within a diverse range of educational contexts, spanning from primary education to adult lifelong learning. Each chapter also concludes with a short summary, demonstrating how these theories translate to practical implications for design. A fascinating response to current developments in educational technology, this is a crucial read for all involved in creating, researching, or making decisions about the use of technologies within educational contexts. (shrink)

This paper -distinguishes between the Hypothesis of Extended Cognition and the Hypothesis of Embedded Cognition, characterizing them as competitors (both motivated by situated, interactive cognitive processing, with the latter being the more conservative of the two interpretations of the data) -clarifies the relation between content externalism and extended cognition -introduces the problem of cognitive bloat, as part of a critical discussion of Clark and Chalmers's "past-endorsement criterion" (if the criterion is embraced, we privilege the internal, endorsing process -- which looks (...) more like an embedded view -- and if the criterion is rejected, bloat follows) and as a problem for extended views more generally -develops a dilemma critical of Clark and Chalmers's "explanatory kinds" argument for extended mind and cognition (arguing that their reasoning faces serious problems regardless of whether one individuates the kinds in question in a fine-grained or a coarse-grained way) -argues that an appeal to functionalism doesn't resolve the issue -argues for the priority, in debates about extended cognition, of the identification of cognitive systems (e.g., because a functionalist approach can't be applied unless we already know what count as inputs and outputs, which requires having already identified the boundaries of the cognitive system). (shrink)

1.Bd. Grundlagen und Wissenschaftslogik.

First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.

An in-depth dialogue on the nature of science between post-materialist biologist Rupert Sheldrake and renowned skeptic Michael Shermer.

In this book, Rupert Read offers the first outline of a resolute reading, following the highly influential New Wittgenstein 'school', of the Philosophical Investigations. He argues that the key to understanding Wittgenstein's later philosophy is to understand its liberatory purport. Read contends that a resolute reading coincides in its fundaments with what, building on ideas in the later Gordon Baker, he calls a liberatory reading. Liberatory philosophy is philosophy that can liberate the user from compulsive patterns of thought, freeing (...) one for possibilities that were previously obscured. Such liberation is our prime goal in philosophy. This book consists in a sequential reading, along these lines, of what Read considers the most important and controversial passages in the Philosophical Investigations 1, 16, 43, 95 & 116 & 122, 130-3, 149-151, 186, 198-201, 217, and 284-6. Read claims that this liberatory conception is simultaneously an ethical conception. The PI should be considered a work of ethics in that its central concern becomes our relation with others. Wittgensteinian liberations challenge widespread assumptions about how we allegedly are independent of and separate from others. Wittgenstein's Liberatory Philosophy will be of interest to scholars and advanced students working on Wittgenstein, and to scholars of the political philosophy of liberation and the ethics of relation. (shrink)

Cultural Writing. Asian American Studies. Translation. This version of the Tao Te Ching extrapolates the premise that wise development of Psyche means downplaying ego's role. Lao Tzu uses a telegraphic style, a kind of Basic Chinese. Once we identify the Chinese character Lao Tzu has used, we must ask how to understand that concept, Chinese or not. If Lao Tzu writes, "Know male, but keep to female," what does this mean in terms of Psyche? What indeed is a sage or (...) a wise man? Allen provides a fresh answer, a vision of wisdom that patriarchal scholars disregard--ego-transcendence in favor of the creative unconscious. (shrink)

Combining anthropological descriptions with historical criticism, Cox situates the Zen arts within contemporary critical discourses.

Risk, ethics and compliance requirements are a daily reality for most organisations. Regulators and stakeholders (including employees) demand more of most organisations, from equality, to anti-corruption, to supply chain ethics. Start-ups stutter and unicorns crash to earth when they get risk wrong. What should be done? Where should you start? How can risk management enable, not hinder, the organization's strategic goals? This book answers these questions -- rightsizing risk for every organization -- using frontline-tested tools, tips, and techniques. Whether you're (...) a purpose-driven changemaker or just struggling to comply with a seemingly unending stream of regulation, we will make risk work for you. (shrink)

Abstract“[…︁] mein Recht muss mir werden!” Hermann Bahr’s Tragicomedy­ Der Querulant­ (1914). At the end of the eighteenth century, people who became notorious for their excessive engagement in legal proceedings started being labeled as “querulents” or “paranoid litigants”. The term “querulents” first appeared in the General Order of the Court for the Prussian States (Allgemeine Gerichtsordnung für die Preußischen Staaten) from July 6, 1793. From there on, the spectrum of juridical measures undertaken against the so‐labeled litigators included classifying these persons (...) as ineligible for legal action and psychiatric hospitalization. The paper discusses to what extent Hermann Bahr rearranges psychiatric and legal knowledge about this special type of the complainer in his tragicomedy Der Querulant, premiered in 1914. This concerns, first, the theatricality of the body and speech, secondly, the use of cultural techniques of writing and, thirdly, conflicting notions of justice. Therefore, the paper analyzes the aesthetic function of querulous behavior in the dramatic structure of the play from the point of view of both media theory and literary theory. (shrink)

Our self, aware presence, knows no resistance to any appearance and, as such, is happiness itself; like the empty space of a room, it cannot be disturbed and is, therefore, peace itself; like this page, it is intimately one with whatever appears on it and is thus love itself; and like water that is not affected by the shape of a wave, it is pure freedom. Causeless joy, imperturbable peace, love that knows no opposite, and freedom at the heart of (...) all experience...this is our ever-present nature under all circumstances. (shrink)

In this book, the author Rupert Riedl investigates the structural and functional correlations of issues considered as "complex". He brilliantly analyzes the definition of complexity, the occurrence of complexity, the meaning of complexity, and last-but-not-least the way complexity is dealt with professionally. In recent years, our view of the world has been split into ever smaller segments – in part due to the increasing importance of the natural sciences and their associated analytical power. This calls for once again focusing (...) on complexity and the holistic aspects, on interdisciplinary and synoptic approaches. This book is a translation of the original German version “Strukturen der Komplexität”, which was published in 2000. The discussion of complexity from the perspective of a biologist has long been overdue when it was published and is still up-to-date. (shrink)

This paper evaluates the Natural-Kinds Argument for cognitive extension, which purports to show that the kinds presupposed by our best cognitive science have instances external to human organism. Various interpretations of the argument are articulated and evaluated, using the overarching categories of memory and cognition as test cases. Particular emphasis is placed on criteria for the scientific legitimacy of generic kinds, that is, kinds characterized in very broad terms rather than in terms of their fine-grained causal roles. Given the current (...) state of cognitive science, I conclude that we have no reason to think memory or cognition are generic natural kinds that can ground an argument for cognitive extension. (shrink)

This fourth edition of Precedent in English Law presents a basic guide to the current doctrine of precedent in England, set in the wider context of the jurisprudential problems which any treatment of this topic involves. Such problems include the nature of _ratio_ _decidendi_ of a precedentand of its binding force, the significance of precedents alongside other sources of law, their role in legal reasoning, and the account which must be taken of them by any general theory of law. Considerable (...) re-writing has been undertaken to update case-law and take account of the possibleimplications for the doctrine of precedent of the impact of European Community law, making it an indispensable work of reference for readers interested in the past history, present state, and future developments of English rules of precedent. (shrink)

Over fifteen years have passed since Cora Diamond and James Conant turned Wittgenstein scholarship upside down with the program of “resolute” reading, and ten years since this reading was crystallized in the major collection _The New Wittgenstein_. This approach remains at the center of the debate about Wittgenstein and his philosophy, and this book draws together the latest thinking of the world’s leading Tractatarian scholars and promising newcomers. Showcasing one piece alternately from each “camp”, _Beyond the Tractatus Wars_ pairs newly (...) commissioned pieces addressing differing views on how to understand early Wittgenstein, providing for the first time an arena in which the debate between “strong” resolutists, “mild” resolutists and “elucidatory” readers of the book can really take place. The collection includes famous “samizdat” essays by Warren Goldfarb and Roger White that are finally seeing the light of day. (shrink)

Dewey's pragmatism rejected ‘truth’ as indicative of an underlying reality, instead ascribing it to valuable connections between aims and ends. Surprisingly, his argument mirrors Bishop Berkeley's Idealism, summarised as ‘esse est percepi’ (to be is to be perceived), whose thinking is shown to be highly pragmatist—but who retained a foundationalist ontology by naming God as the guarantor of all things. I argue that while this position is unsustainable, pragmatism could nonetheless be strengthened through an ontological foundation. Koopman's charges of foundationalist (...) ‘givenism’ in Dewey's work, and in his promotion of the scientific method, are not proven. However, Koopman's ‘genealogical pragmatism’ may develop Deweyan educational theory by addressing dilemmas around curricular study. Koopman's arguments also point towards a missing ontological piece in Dewey's theory of knowledge. In the final section of the article I offer a dialogic ontology as compatible with pragmatism. This dialogical ontology provides both an ethical foundation through interrelatedness, and a generative theory of meaning and experience, as emergent from the encounter with difference. In this framework, to be is to respond—or be responded to. I offer the metaphor of ‘realisation’ to capture the human experience implied by this ontological stance. (shrink)

Our world culture is founded on the belief that consciousness is derived from matter, giving rise to the materialistic assumption that informs almost every aspect of our lives as is the root cause of the suffering within individuals, the conflicts between communities and nations, and the degradation of our environment. The Nature of Consciousness exposes the fallacy of this belief and suggests that the recognition of the presence, the primacy and the nature of consciousness is the prerequisite for any new (...) paradigm that is to address these issues at their core."--Back cover. (shrink)

This paper presents the leading idea of my doctoral dissertation and thus has been shaped by the reactions of all the members of my thesis committee: Charles Chastain, Walter Edelberg, W. Kent Wilson, Dorothy Grover, and Charles Marks. I am especially grateful for the help of Professors Chastain, Edelberg, and Wilson; each worked closely with me at one stage or another in the development of the ideas contained in the present work. Shorter versions of this paper were presented at the (...) 47th Annual Northwest Conference on Philosophy (1995), the 1996 Mid-South Philosophy Conference, the 1997 meeting of the Central Division of the American Philosophical Association, and at the University of Washington, Seattle; thanks to all audiences for their insightful comments and questions and also to my conference commentators, Eric Gampel, Jonathan Cohen, and Bruce Glymour, respectively, each of whom offered a thoughtful critique. Lastly, I extend my gratitude to anonymous referees, including two from Mind and Language, whose remarks led to significant improvements in the paper. Address for correspondence: 13416, 4th Ave. S., Seattle, WA 98168, USA E-mail: robrupert@aol.com.. (shrink)

This paper engages critically with anti-representationalist arguments pressed by prominent enactivists and their allies. The arguments in question are meant to show that the “as-such” and “job-description” problems constitute insurmountable challenges to causal-informational theories of mental content. In response to these challenges, a positive account of what makes a physical or computational structure a mental representation is proposed; the positive account is inspired partly by Dretske’s views about content and partly by the role of mental representations in contemporary cognitive scientific (...) modeling. (shrink)

Finlayson argues that ‘post-truth’ is nothing new. In this response, I motivate a more modest position: that it is something new, to some extent, albeit neither radically new nor brand new. I motivate this position by examining the case of climate-change-denial, called by some post-truth before 'post-truth'. I examine here the (over-determined) nature of climate-denial. What precisely are its attractions?; How do they manage to outweigh its glaring, potentially-catastrophic downsides? I argue that the most crucial of all attractions of climate-denial (...) is that it involves the denier in a kind of fantasised power over reality itself: namely, over the nature of our planetary system, and thus of life itself. Climate-denial pretends to give the denier a power greater than that of nature, including in nature's 'rebellion' against humanity, what James Lovelock calls Gaia's incipient and coming 'fever'. Climate-denial seems to give the denier freedom from truth itself, in the case of the most consequential truth at present bearing down upon humanity. The most crucial of all the attractions of climate-denial is then that it provides would-be libertarians an ultimate freedom. They reject the reality of human-triggered climate-change, in the end, because they are unwilling to be ‘bound’ by anything, not even truth itself. Climate-denial has been around for a while, but not for more than 30-35 years or so. I thus suggest that Finlayson is right to be sceptical of the claim that post-truth is radically new and extremely recent, but I suggest that it is relativelynew and has been with us for only about a generation or at most two. Keywords: climate-change, climate-denial, libertarianism, Nietzsche, Wittgenstein. (shrink)

In this paper, I claim that extant empirical data do not support a radically embodied understanding of the mind but, instead, suggest (along with a variety of other results) a massively representational view. According to this massively representational view, the brain is rife with representations that possess overlapping and redundant content, and many of these represent other mental representations or derive their content from them. Moreover, many behavioral phenomena associated with attention and consciousness are best explained by the coordinated activity (...) of units with redundant content. I finish by arguing that this massively representational picture challenges the reliability of a priori theorizing about consciousness. (shrink)

The Buddhist technical term was first translated as ‘mindfulness’ by T.W. Rhys Davids in 1881. Since then various authors, including Rhys Davids, have attempted definitions of what precisely is meant by mindfulness. Initially these were based on readings and interpretations of ancient Buddhist texts. Beginning in the 1950s some definitions of mindfulness became more informed by the actual practice of meditation. In particular, Nyanaponika's definition appears to have had significant influence on the definition of mindfulness adopted by those who developed (...) MBSR and MBCT. Turning to the various aspects of mindfulness brought out in traditional Theravāda definitions, several of those highlighted are not initially apparent in the definitions current in the context of MBSR and MBCT. Moreover, the MBSR and MBCT notion of mindfulness as ‘non-judgmental’ needs careful consideration from a traditional Buddhist perspective. Nevertheless, the difference in emphasis apparent in the theoretical definitions of mindfulness may not be so significant in the actual clinical application of mindfulness techniques. (shrink)