Criticisms of the “container” model of pregnancy picturing female and embryo as separate entities multiply in various philosophical and scientific contexts during the last decades. In this paper, we examine how this model underlies received views of pregnancy in evolutionary biology, in the characterization of the transition from oviparity to viviparity in mammals and in the selectionist explanations of pregnancy as an evolutionary strategy. In contrast, recent evo-devo studies on eutherian reproduction, including the role of inflammation and new maternal cell (...) types, gather evidence in favor of considering pregnancy as an evolved relational novelty. Our thesis is that from this perspective we can identify the emergence of a newhistoricalindividual in evolution. In evo-devo, historical units are conceptualized as evolved entities which fulfill two main criteria, their continuous persistence and their non-exchangeability. As pregnancy can be individuated in this way, we contend that pregnant females are historical individuals. We argue that historical individuality differs from, and coexists with, other views of biological individuality as applied to pregnancy (the physiological, the evolutionary and the ecological one), but brings forward an important new insight which might help dissolve misguided conceptions. (shrink)

Aristotle’s influence on D’Arcy Thompson was praised by Thompson himself and has been recognized by others in various respects, including the aesthetic and normative dimensions of biology, and the multicausal explanation of living forms. This article focuses on the relatedness of organic forms, one of the core problems addressed by both Aristotle’s History of Animals (HA), and the renowned chapter of Thompson’s On Growth and Form (G&F), “On the Theory of Transformations, or the Comparison of Related Forms.” We contend that, (...) far from being an incidental inspiration stemming from Thompson’s classicist background, his translation of HA played a pivotal role in developing his theory of transformations. Furthermore, we argue that Thompson’s interpretation of the Aristotelian method of comparison challenges the prevailing view of Aristotle as the founder of “typological essentialism,” and is a key episode in the revision of this narrative. Thompson understood that the method Aristotle used in HA to compare animal forms is better comprehended as a “method of transformations,” leading to a morphological arrangement of animal diversity, as opposed to a taxonomical classification. Finally, we examine how this approach to the relatedness of forms lay the foundation for a causal understanding of parts and their interconnections. Although Aristotle and Thompson emphasized distinct types of causes, we contend that they both differ in a fundamental sense from the one introduced by Darwin’s theory of natural selection, which was formulated as a solution to the species problem rather than the form problem. We conclude that Thompson’s interpretation of Aristotle’s approach to form comparison has not only impacted contemporary scholarship on Aristotle’s biology, but revitalized a perspective that has regained significance due to the resurgence of the problem of form in evo-devo. (shrink)

This paper proposes a formal top-level model of explaining the outputs of machine-learning-based decision-making applications and evaluates it experimentally with three data sets. The model draws on AI & law research on argumentation with cases, which models how lawyers draw analogies to past cases and discuss their relevant similarities and differences in terms of relevant factors and dimensions in the problem domain. A case-based approach is natural since the input data of machine-learning applications can be seen as cases. While the (...) approach is motivated by legal decision making, it also applies to other kinds of decision making, such as commercial decisions about loan applications or employee hiring, as long as the outcome is binary and the input conforms to this paper’s factor- or dimension format. The model is top-level in that it can be extended with more refined accounts of similarities and differences between cases. It is shown to overcome several limitations of similar argumentation-based explanation models, which only have binary features and do not represent the tendency of features towards particular outcomes. The results of the experimental evaluation studies indicate that the model may be feasible in practice, but that further development and experimentation is needed to confirm its usefulness as an explanation model. Main challenges here are selecting from a large number of possible explanations, reducing the number of features in the explanations and adding more meaningful information to them. It also remains to be investigated how suitable our approach is for explaining non-linear models. (shrink)

Of all the thinkers of the century of genius that inaugurated modern philosophy, none lived an intellectual life more rich and varied than Gottfried Wilhelm Leibniz. Maria Rosa Antognazza's pioneering biography provides a unified portrait of this unique thinker and the world from which he came. At the centre of the huge range of Leibniz's apparently miscellaneous endeavours, Antognazza reveals a single master project lending unity to his extraordinarily multifaceted life's work. Throughout the vicissitudes of his long life, Leibniz (...) tenaciously pursued the dream of a systematic reform and advancement of all the sciences. As well as tracing the threads of continuity that bound these theoretical and practical activities to this all-embracing plan, this illuminating study also traces these threads back into the intellectual traditions of the Holy Roman Empire in which Leibniz lived and throughout the broader intellectual networks that linked him to patrons in countries as distant as Russia and to correspondents as far afield as China. (shrink)

In this paper I argue that, in Leibniz’s mature metaphysics, primary matter is not a positive constituent which must be added to the form in order to have a substance. Primary matter is merely a way to express the negation of some further perfection. It does not have a positive ontological status and merely indicates the limitation or imperfection of a substance. To be sure, Leibniz is less than explicit on this point, and in many texts he writes as if (...) primary matter were a positive constituent of a substance. It seems to me, however, that the view most in keeping with the thrust of his mature philosophical system is that captured by a striking remark of 1695: “Materia rerum est nihilum: id est limitatio [The matter of things is nothing: that is, limitation].” This becomes especially apparent in texts showing that Leibniz’s conception of primary matter corresponds to his conception of creaturely limitation. I start by discussing the notion of primary matter in the scholastic tradition. I then show that although Leibniz places the scholastic terminology of primary matter at a crucial juncture of his metaphysics, he thinks of primary matter in a way which significantly deviates from earlier scholastic views. I conclude that despite his adoption of distinctive terminology of Aristotelian scholasticism, instead of holding a broadly Aristotelian concept of primary matter as the ultimate subject of inherence, Leibniz thinks of primary matter according to a Neoplatonic blue-print in which matter is non-being, privation, mere absence of perfection. (shrink)

This paper advances the view that the history of philosophy is both a kind of history and a kind of philosophy. Through a discussion of some examples from epistemology, metaphysics, and the historiography of philosophy, it explores the benefit to philosophy of a deep and broad engagement with its history. It comes to the conclusion that doing history of philosophy is a way to think outside the box of the current philosophical orthodoxies. Somewhat paradoxically, far from imprisoning its students in (...) outdated and crystallized views, the history of philosophy trains the mind to think differently and alternatively about the fundamental problems of philosophy. It keeps us alert to the fact that latest is not always best, and that a genuinely new perspective often means embracing and developing an old insight. The upshot is that the study of the history of philosophy has an innovative and subversive potential, and that philosophy has a great deal to gain from a long, broad, and deep conversation with its history. (shrink)

Background: Many studies have explored personal values in nursing, but none has assessed whether the predictions made by the theory of intergenerational value change are true for the different generations of nursing professionals and students. This theory predicts a shift in those personal values held by younger generations towards ones focussed on self-expression. Research question: The purpose of the study was to identify intergenerational differences in personal values among nursing professionals and nursing students and to determine whether generational value profiles (...) fit the predictions made by the theory. Research design: An exploratory comparative design with a cross-sectional survey method was used. Participants and research context: Participants were recruited from four public hospitals and 10 Primary Care Centres in medium-size cities in Spain. A sample of 589 nurses and 2295 nursing students participated in the study. An open survey method was used to collect data that were classified grouping reported values into categories following a method of value lexicon construction and analysed by contingency tables with Pearson’s χ2 and standardized residuals. Ethical considerations: Approval to conduct the study was obtained from the Deans of the nursing schools and the Directors of Nursing of the institutions. Anonymity was guaranteed, participation was voluntary and participants were informed of the purpose of the study. Findings: The results can be synthesized in two age-related trends in the reporting of values among three groups of participants. First, among younger nurses and students, some nursing core values (e.g. ethical and professional) decreased in importance, while other values centred on social relationships and personal well-being increased. Discussion and Conclusion: This study shows intergenerational change in personal values among both nursing students and young nursing professionals. Findings suggest the need to pay more attention to value training and professional socialization during the schooling period. (shrink)

This paper presents the evaluation of the alpha version of a gamified tool called Call for Papers: The Game (CfP:TG), specially designed for teaching scientific writing in the training of future engineers. A non-probabilistic convenience sampling was carried out with the participation of engineering students from a Peruvian public university. The short version of the user experience questionnaire (UEQ) was applied, and usability was qualitatively evaluated. The main results indicate that the Pragmatic Quality of CfP:TG is in the neutral range (...) with a value of 0.729, and the Hedonic Quality receives a positive evaluation with a value of 1.089. (shrink)

In the age of neoliberalism, feminists strongly disagree on the ideal legal status of prostitution while the pro-prostitution lobby endeavours to keep their male-dominated business running smoothly. Feminist debates should be concerned with the sex buyers' belief system about women, which is likely to have practical consequences in the way they behave with women (prostituted and non-prostituted) in terms of sexuality and, therefore, for feminist purposes of equality, on a broader scale. A Critical Discourse Analysis of buyer-authored online reviews of (...) prostituted women provides the opportunity to verify whether the relationship they establish with them is based on democratic mutual equality or gendered power relations driven by domination and subordination.En la era del neoliberalismo, no hay consenso entre las feministas acerca del estatus legal que debería tener la prostitución; mientras, el lobby pro-prostitución intenta proteger tan lucrativo negocio. Los debates feministas deben abordar críticamente el sistema de creencias de los sujetos prostituyentes, en tanto que afecta a cómo actúan con las mujeres (prostituidas y no prostituidas) dentro del marco de la sexualidad y, por tanto, al potencial logro de la igualdad fáctica a nivel social. El análisis crítico del discurso online de los sujetos prostituyentes sobre las mujeres prostituidas permite comprobar si las relaciones que establecen con ellas están basadas en términos igualitarios o en la dicotomía dominación-subordinación característica de las relaciones de poder de género. (shrink)

Denmark was once at the forefront of nuclear research, operating three experimental nuclear reactors at the research facility at Risø, close to Copenhagen. However, the 1985 resolution of the Danish Parliament excluded nuclear power from the national energy mix. In 2003, the Parliament passed a resolution on the decommissioning of the nuclear facility at Risø, including plans for establishing a permanent solution for radioactive waste management. To understand the ensuing socio-technical controversy, we employ the “hybrid forum” framework that emphasizes the (...) entangled political-epistemological role of the municipalities and protest groups. They mobilized political resistance while also performing “research in the wild.” In 2016, the protest groups became part of an institutionalized “hybrid forum” where they could negotiate directly with experts and government representatives. We conclude that municipalities and protest groups were instrumental in changing the Danish position on radioactive waste management from final repository to long-term storage at Risø. (shrink)

La crítica kantiana legó una doble herencia a la biología decimonónica: su noción de ciencia basada en el mecanicismo newtoniano configuró epistemológicamente la teoría de la evolución darwinista, mientras que su comprensión de los organismos se tradujo en una morfología teleológica. En este artículo planteamos dos cuestiones en torno la relación entre las ideas de Kant y Darwin: 1) si Kant habría considerado a Darwin el Newton de la biología, a lo que, con matices, respondemos afirmativamente; 2) si la física (...) newtoniana es hoy suficiente para naturalizar lo orgánico. Nuestra respuesta negativa se fundamenta en las ciencias de la autoorganización y la evo-devo, que permiten plantear la naturalización de la concepción kantiana de los organismos. (shrink)

Despite the proliferation of articles and edited volumes on EvoDevo (evolutionary developmental biology), only a couple of monographs dealing systematically with the conceptual challenges posed by the reintroduction of development into the structure of evolutionary theory are available (Gould 2002; Amundson 2005). In Requiem for the Centaurus: An Epistemological Approach to Evolutionary Developmental Biology, Footnote1 Gustavo Caponi reorganizes the pieces of work he has been publishing in recent years on different historical and conceptual aspects of evolutionary biology into a long, (...) coherent, elegant, and thought-provoking argument that deserves to be read from beginning to end. (shrink)

La biología sintética mantiene una relación muy singular con la teoría evolutiva: por un lado, parte de una interpretación ingenieril de la evolución para fundar su aproximación al diseño de bioartefactos; por otro, la biología sintética aspira, en última instancia, a deshacerse de la evolución creando organismos de novo que se comporten de un modo predecible. Tras examinar las tres grandes propiedades que aparecen recurrentemente en la descripción sintética de los nuevos artefactos orgánicos, argumentaré que la biología sintética se erige (...) sobre una concepción de los organismos y en particular de la relación de estos con su legado histórico que ha sido profundamente cuestionada por la biología evolucionista contemporánea. (shrink)

The purpose of the present paper is to reply to a misleading paper by M. Sachs entitled “Einstein's later view of the Twin Paradox” (TP) (Found. Phys. 15, 977 (1985)). There, by selecting some passages from Einstein's papers, he tried to convince the reader that Einstein changed his mind regarding the asymmetric aging of the twins on different motions. Also Sachs insinuates that he presented several years ago “convincing mathematical arguments” proving that the theory of relativity does not predict asymmetrical (...) aging in the TP. Here we give a definitive treatment to the clocks problem showing that Sachs' “convincing mathematical arguments” are non sequitur. Also, by properly quoting Einstein, we show that his later view of the TP coincides with the one derived from the rigorous theory of time developed in this paper. (shrink)

La libertad se sitúa, desde Kant, más allá de los límites de la razón, y este aspecto persiste hasta el pensamiento de Kierkegaard. La elección de ser libres, que se inaugura como preocupación en O lo uno o lo otro de 1843 y que también ya estaba presente en Kant, se pone de relieve ante la imperiosa necesidad de mostrar que la libertad (Friheden) es el fundamento propiamente subjetivo y que, como tal, no puede ser impuesto ni demostrado desde afuera, (...) es decir, no puede ser aplicado ni mostrado por ninguna ciencia particular, sino en una instancia denominada ética (der Ethiske). Sin embargo, la subjetividad ética que el juez Guillermo desarrolla presenta límites, ya que, ante la aparición del concepto de pecado, el concepto de libertad se ve resignificado, dando lugar a un nuevo modo de concebir la libertad en las obras posteriores del pensador danés. (shrink)

The category of metaphysical evil introduced by Leibniz appears to cast a sinister shadow over the goodness of creation. It seems to imply that creatures, simply in virtue of not being gods, are to some degree intrinsically and inescapably evil. After briefly unpacking this difficulty and outlining a recent attempt to deal with it, this paper returns to the texts to propose a novel and multilayered understanding of Leibniz’s category of metaphysical evil by reading it against the backdrop of the (...) traditional typologies of evil with which he was unquestionably familiar. It comes to the conclusion that metaphysical evil plays two key roles for Leibniz. First, it captures what Aquinas and especially Suarez meant by ‘natural evil’. Contrary to the common assumption that it is Leibniz’s category of physical evil that holds the place of natural evil, the paper shows that Leibniz’s physical evil corresponds to Augustine’s category of evil of punishment for sin whereas natural evil – intended as a kind of evil which is not related to moral responsibility -- is subsumed under metaphysical evil. Secondly, the category of metaphysical evil covers also the notion of original creaturely imperfection. In classifying creaturely limitation as a kind of evil Leibniz breaks from the Augustinian-Thomist-Scholastic tradition and its distinction between negatio and privatio. On the other hand, notwithstanding this important break, Leibniz’s notion of metaphysical evil is intended to account for something which is firmly within the broadly Augustinian-Scholastic tradition, namely the ascription to all creatures of a limitation that stems from their being created ex nihilo. Finally, the paper returns a verdict of non-guilty to the charge that Leibniz’s metaphysical evil implies that creatures qua creatures are to some extent necessarily intrinsically evil. More generally, in typical Leibnizian fashion, the notion of metaphysical evil will appear to be a complex mix of indebtedness to tradition and bending of received doctrines into something significantly different. (shrink)

This paper explores the development of Leibniz’s metaphysics of the Incarnation in the context of his philosophy. In particular it asks to what extent Leibniz’s repeated endorsement of the traditional analogy between the union in humankind of soul (mind) and body, and the union in Christ of divine and human natures, could be accommodated by his more general metaphysical doctrines. Such an investigation highlights some of the deepest commitments in Leibniz’s theory of substance as well as detect in it some (...) unresolved tensions. The paper comes to the conclusion that puzzling points of Leibniz’s metaphysics of the Incarnation, rather than being problems specific to his theology, uncover tensions in his theory of substance as such – tensions converging on the vexed question of whether there can or cannot be genuine corporeal substances in Leibniz’s mature philosophy. (shrink)

The notion of fitness is usually equated to reproductive success. However, this actualist approach presents some difficulties, mainly the explanatory circularity problem, which have lead philosophers of biology to offer alternative definitions in which fitness and reproductive success are distinguished. In this paper, we argue that none of these alternatives is satisfactory and, inspired by Mumford and Anjum’s dispositional theory of causation, we offer a definition of fitness as a causal dispositional property. We argue that, under this framework, the distinctiveness (...) that biologists usually attribute to fitness—namely, the fact that fitness is something different from both the physical traits of an organism and the number of offspring it leaves—can be explained, and the main problems associated with the concept of fitness can be solved. Firstly, we introduce Mumford and Anjum's dispositional theory of causation and present our definition of fitness as a causal disposition. We explain in detail each of the elements involved in our definition, namely: the relationship between fitness and the functional dispositions that compose it, the emergent character of fitness, and the context-sensitivity of fitness. Finally, we explain how fitness and realized fitness, as well as expected and realized fitness are distinguished in our approach to fitness as a causal disposition. (shrink)

This contribution discusses Leibniz’s conception of the Christian church, his life-long ecumenical efforts, and his stance toward religious toleration. Leibniz’s regarded the main Christian denominations as particular churches constituting the only one truly catholic or universal church, whose authority went back to apostolic times, and whose theology was to be traced back to the entire ecclesiastical tradition. This is the ecclesiology which underpins his ecumenism. The main phases and features of his work toward reunification of Protestants and Roman Catholics, and (...) unification of Protestant churches are briefly explored, before turning to the issue of religious toleration. It is argued that a remarkably inclusive conception of toleration can be gleaned from a broad sample of Leibniz’s writings and correspondence. It is thanks to the philosophical and theological grounds of this conception that toleration can in principle be extended, for Leibniz, to all men and women of good will, including non-Christians, pagans, and atheists. (shrink)

Martha Nussbaum grounds her version of the capabilities approach in political liberalism. In this paper, we argue that the capabilities approach, insofar as it genuinely values the things that persons can actually do and be, must be grounded in a hybrid account of liberalism: in order to show respect for adults, its justification must be political; in order to show respect for children, however, its implementation must include a commitment to comprehensive autonomy, one that ensures that children develop the skills (...) necessary to make meaningful choices about whether or not to exercise their basic capabilities. Importantly, in order to show respect for parents who do not necessarily recognize autonomy as a value, we argue that the liberal state, via its system of public education, should take on the role of ensuring that all children within the state develop a sufficient degree of comprehensive autonomy. (shrink)

Pere Alberch played a pivotal role in shaping the field of evolutionary developmental biology during the 1980s and 1990s. Whereas initially his contributions were sidelined by the empirical advancements of the molecular revolution in developmental and evolutionary biology, his theoretical insights have left a lasting impact on the discipline. This article provides a comprehensive review of the legacy and evolvability of Alberch's ideas in contemporary evo-devo, which included the study of morphogenesis as the proper level of developmental causation, the interplay (...) between developmental constraints and natural selection, the epistemic role of teratologies, the origin of evolutionary novelties and the concept of evolvability. (shrink)

This article presents research on the scale of the phenomenon of sexual violence against students at selected 33 universities across Poland, the mechanisms used to combat the problem and the awareness of students on the subject. The study focuses on the practical dimension of combating sexual violence against students in the Polish academic environment. It looks at the existence and functioning of both specialised bodies and the procedures used to help the victims and punish the perpetrators. Additionally, the paper describes (...) how the diversity of available legal measures to address the problem by both helping the victims and holding perpetrators accountable creates the issue of the coexistence of two systems—criminal and intra-university. Presenting preliminary results of gathered opinions of universities’ officials regarding functioning of the bodies specialised in combating sexual violence shows not only the most dominant observations and conclusions the professionals have regarding the functions they hold at their home universities, but also main challenges that have to be considered in both creating sufficient policies in order to deal with sexual violence and conducting comprehensive research on said phenomenon. (shrink)

Leibniz is not commonly numbered amongst canonical writers on toleration. One obvious reason is that, unlike Locke, he wrote no treatise specifically devoted to that doctrine. Another is the enormous amount of energy which he famously devoted to ecclesiastical reunification. Promoting the reunification of Christian churches is an objective quite different from promoting the toleration of different religious faiths – so different, in fact, that they are sometimes even construed as mutually exclusive. Ecclesiastical reunification aims to find agreement at least (...) on the most important doctrines. Religious toleration involves accepting and respecting disagreement even on the most important doctrines. If one regards these two projects as alternative rather than complementary strategies for dealing with religious diversity, Leibniz might more readily be characterised as an ecumenist rather than a tolerationist. Such appears to be the conclusion, at any rate, implicit in the balance of critical literature on these topics: whereas a steady stream of studies has discussed Leibniz’s project of ecclesiastical reunification, only a meager trickle has been devoted to his views on toleration; and some of these studies go so far as to conclude that Leibniz had no doctrine of toleration at all. This paper will attempt to show, on the contrary, that a robust, many-layered, and unusually inclusive doctrine of toleration can be gleaned from Leibniz’s writings. This doctrine operated at least at three different levels: philosophical, theological, and pragmatic. As this implies, the doctrine of religious toleration, rather than being in collision with Leibniz’s core project of ecclesiastical reunification, was an essential element of that very project: it should be seen, in other words, not as a competing goal, but as a necessary first step toward ecclesiastical reunification. Yet at the same time it will also emerge that Leibniz’s doctrine of toleration was no mere function of this intra-Christian project of reunification: rather it was a still more fundamental principle which extended beyond the ecumenical project as well. It had the resources for accepting and respecting irreducible religious diversity and disagreement on points of importance not only between Christian communities, but also between Christians and non-Christians, including, in principle, even the atheists. These points will emerge from a discussion of statements on the philosophical, theological, and pragmatic justifications of religious toleration scattered throughout Leibniz’s sprawling corpus of writings. (shrink)

Throughout his long intellectual life, Leibniz penned his reflections on Christian theology, yet this wealth of material has never been systematically gathered or studied. This book addresses an important and central aspect of these neglected materials—Leibniz’s writings on two mysteries central to Christian thought, the Trinity and the Incarnation. -/- From Antognazza’s study emerges a portrait of a thinker surprisingly receptive to traditional Christian theology and profoundly committed to defending the legitimacy of truths beyond the full grasp of human reason. (...) This view of Leibniz differs strikingly from traditional perceptions of the philosopher as a “hard” rationalist and quasi-deist. Antognazza also sets Leibniz’s writings in the context of the important theological controversies of his day. (shrink)

The planet seems to be heading into an ecological catastrophe, in which the earth will become uninhabitable for many species, including human beings. At the same time we humans are beset by appalling injustices. The Rio Declaration which addressed both these sets of problems contains conceptual contradictions about ‘development and ‘nature’. This paper addresses the issue of whether it is logically possible to work for both global justice and ecological sustainability. The article proposes a way of responding to the spirit (...) of the Rio Declaration without reinstating its contradictions; considers a posthuman perspective on the issue; and proposes a phenomenological approach to ethics and justice which would include both the human and more-than-human parts of the world. In section the implications for education are drawn out, in terms of ‘learning to mind’. Finally, links are drawn to the Journal theme of translation. (shrink)

The extensive, profound and influential oeuvre of Charles Taylor has inspired generations of thinkers. But how can we explore such a body of work? As we try to show in this Special Issue: by understanding him literally and making use of his notion of moral maps – or, differently put, by ‘mapping’ Charles Taylor. As he is far too modest a person to reveal to us his own moral atlas, we have decided to seize the occasion of his 85th birthday (...) to ask several of his renowned colleagues, students and interlocutors to contribute to the reconstruction of such a map. This introduction develops three ‘mountain ridges’ in this cartography – a philosophical anthropology in spatial terms, the indispensable motif of dialogue, and the role of political life –, around which the following 24 illuminating appraisals are grouped. (shrink)

Connectedness is a significant element of sociality that occurs not only ideally and ‘leiblich’, but also consists of a material dimension. This is established through the materiality of the human body and points beyond it at the same time. The material aspect of connectedness is not simply social but has a social meaning nonetheless: Materiality has an impact on society and on the quality of human coexistence with the environment. To be able to describe this aspect, we use approaches of (...) feminist (neo-)materialisms. First, a neo-materialist perspective on subjectivity is developed, which, in addition to the immaterial aspects of the social, is also able to grasp the dependence of the development of human bodies on their environment. Connectedness as a material-discursive phenomenon adds a neo-materialist dimension to the established ‘phenomenological’ interpretation of the resonance concept that integrates interactions of repulsion or alienation by understanding feelings of alienation, rejection, or the silencing of the world-relationship as well as a resonant world-relationship always also as agentic cuts of the LeibKörper. (shrink)

Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological disorders difficult to study in humans, chimeric models with human neural tissue could help advance our understanding of neuropathophysiology. In (...) this article, we examine whether the introduction of human neural tissue and any consequent cognitive change is relevant to the way we ought to treat chimeras. We argue that changes in cognitive abilities are morally relevant to the extent that they increase the capacities that affect the moral status of any entity, including awareness, autonomy, and sociability. We posit that no being, regardless of species, should be treated in a way that is incommensurate with its moral status. Finally, we propose a framework that can be used to guide ethical assessment of research involving chimeras with advanced cognitive capacities. We advance this framework as a useful tool for bringing relevant considerations to the forefront for those considering the ethical merit of proposed chimeric research. In doing so, we examine concepts relevant to the question of how any entity may be treated, including moral status, dignity, and capacities. (shrink)

The importance of socio-economic impacts from the introduction and use of genetically modified crops is reflected in increasing efforts to include them in regulatory frameworks. Aiming to identify and understand the present knowledge on SEI of GM crops, we here report the findings from an extensive study of the published international scientific peer-reviewed literature. After applying specified selection criteria, a total of 410 articles are analysed. The main findings include: limited empirical research on SEI of GM crops in the scientific (...) literature; the main focus of the majority of the published research is on a restricted set of monetary economic parameters; proportionally, there are very few empirical studies on social and non-monetary economic aspects; most of the research reports only short-term findings; the variable local contexts and conditions are generally ignored in research methodology and analysis; conventional agriculture is the commonly used comparator, with minimal consideration of other substantially different agricultural systems; and there is the overall tendency to frame the research upon not validated theoretical assumptions, and to over-extrapolate small-scale and short-term specific results to generalized conclusions. These findings point to a lack of empirical and comprehensive research on SEI of GM crops for possible use in decision-making. Broader questions and improved methodologies, assisted by more rigorous peer-review, will be required to overcome current research shortcomings. (shrink)

Argues that academics’ intellectual engagement with a public beyond the walls of their own specialties, and even beyond the walls of the academy, was long a commonplace and significant part of the work of professors and writers in the humanities.

The article highlights the origins of Freudian thought as the germ of the advent of psychoanalysis and, in particular, the discovery of the unconscious as one of the disruptive effects that changed the course of human history. The writing suggests that Freud’s Jewishness, in post-Enlightenment Europe in the 19th century, enabled an intellectual formation capable of sustaining political impulses that were not always explicit in the history of psychoanalytic theory. By retracing the path of building ties with the polis, established (...) by the first generations of European analysts, in the so-called Red Vienna of the 1920s (Danto, 2019), the authors articulate links between psychoanalysis and politics. Finally, they discuss the symptomatic effects of the erasure of the political dimension, through the supposed neutrality of the psychoanalytic movement in Brazil and, especially, in the context of the Brazilian dictatorship. (shrink)

Im vorliegenden Beitrag geht es – angesichts der enormen gesellschaftlichen Verbreitung von Quantifizierungstechniken und -imperativen im digitalen Zeitalter – um psychische Bedeutungen des digitalen Messens, Zählens und Vergleichens und um die Faszination für diese Operationen. Mit Blick auf eine sozio- und psychoanalytisch ausgerichtete Hermeneutik der Zahl werden erste Ergebnisse des Forschungsprojekts »Das vermessene Leben« erörtert. Eine der zentralen Fragen ist dabei, wie sich Merkmale digitaler Quantifizierung mit psychischen Dispositionen verbinden, spezifische Bewältigungs- und Abwehrmuster auslösen oder welche Rolle etwa die Externalisierung (...) von Affekt- oder Norm-Regulationen spielt. Schließlich wird nachgezeichnet, wie daraus neue Konstellationen und kulturelle Vorstellungen von Normalität und Pathologie hervorgehen können. (shrink)