My heart was removed and replaced on May 17, 2006. No melodrama is intended here, just an unadorned factual statement. Transplants are transformative. In my case, that transformation led to bioethics.

This book is a succinct introduction to the orienting of attention.

Anthony Everett () argues that those who embrace the reality of fictional entities run into trouble when it comes to specifying criteria of character identity. More specifically, he argues that realists must reject natural principles governing the identity and distinctness of fictional characters due to the existence of fictions which leave it indeterminate whether certain characters are identical and the existence of fictions which say inconsistent things about the identities of their characters. Everett's critique has deservedly drawn much attention and (...) a number of defensive moves have been made by, or on the behalf of, fictional realists. My goal in this paper is to move this debate on a further step. I have three goals: to clarify the importance of Everett's discussion of identity criteria within the context of fictional realism, to reassess Everett's objections to realism in light of the resultant literature, and to develop a novel strategy for responding to Everett's concerns. On the approach to be developed, the problems emerge due to an indeterminacy inherent in the concept of a fictional character itself. (shrink)

The evolution of nonconceptive sexuality in bonobos and chimpanzees is discussed from a functional perspective. Bonobos and chimpanzees have three functions of sexual activity in common (paternity confusion, practice sex, and exchange for favors), but only bonobos use sex purely for communication about social relationships. Bonobo hypersexuality appears closely linked to the evolution of female-female alliances. I suggest that these alliances were made possible by relaxed feeding competition, that they were favored through their effect on reducing sexual coercion, and that (...) they are ultimately responsible for the relaxed social conditions that allowed the evolution of “communication sex.”. (shrink)

In Reading in the Brain, Stanislas Dehaene presents a compelling account of how the brain learns to read. Central to this account is his neuronal recycling hypothesis: neural circuitry is capable of being ‘recycled’ or converted to a different function that is cultural in nature. The original function of the circuitry is not entirely lost and constrains what the brain can learn. It is argued that the neural niche co-evolves with the environmental niche in a way that does not undermine (...) the core ideas of neuronal recycling, but which is quite different from the models of cognitive and cultural evolution provided by evolutionary psychology and epidemiology. Dehaene contrasts neuronal recycling with a naïve model of the brain as a general learning device that is unconstrained in what it can learn. Consequently a tension develops in Dehaene's account of the role of plasticity in the acquisition of language. It is argued that the functional and structural changes in the brain that Dehaene documents in great detail are driven by learning and that this learning-driven plasticity does not commit us to a naïve model of the brain. (shrink)

It is widely maintained that a clinical trial is ethical only if some form of equipoise between the treatments being compared obtains. To be in equipoise between two treatments A and B is to be cognitively indifferent between the statement ‘A is strictly more effective than B’ and its negation. It is natural to claim that equipoise regarding A and B is necessary for randomised assignment to treatments A and B to be beneficent and non‐maleficent and is sufficient for such (...) an assignment to be fair. Cashing this out precisely is difficult, and various forms of equipoise have been discussed which consider whose equipoise is relevant to the decision. This is to make judgement of equipoise something to be managed socially, while its prima facie significance is supposedly cognitive. Recent reconstructions of equipoise‐like concepts in epistemology give clues about how to understand equipoise cognitively. In this paper I examine some of this work and discuss how successful it has been. I suggest that while this work is promising, it still has far to go, and that while equipoise remains the best theory we have of the cognitive justification for clinical trials, it is nonetheless incoherent. (shrink)

Naturalistic philosophers ought to think that the mind is continuous with the rest of the world and should not, therefore, be surprised by the findings of the extended mind, cognitive integration and enactivism. Not everyone is convinced that all mental phenomena are continuous with the rest of the world. For example, intentionality is often formulated in a way that makes the mind discontinuous with the rest of the world. This is a consequence of Brentano’s formulation of intentionality, I suggest, and (...) can be overcome by revealing that the concept of intentional directedness as he receives it from the Scholastics is quite consistent with the continuity thesis. It is only when intentional directedness is conjoined with intentional inexistence that intentionality and content are consistent with a discontinuity thesis (such as Brentano’s thesis). This makes room to develop an account of intentional directedness that is consistent with the continuity thesis in the form of Peirce’s representational principle. I also argue against a form of the discontinuity thesis in the guise of the derived/underived content distinction. Having shown that intentionality is consistent with the continuity thesis I argue that we should focus on intentionality and representation as bodily enacted. I conclude that we would be better off focussing on representation and intentionality in action rather than giving abstract functional accounts of extended cognition. (shrink)

Balancing practical and theoretical knowledge,Political Scienceis a comprehensive and jargon-free introduction to the fieldrs"s basic concepts and themes. This bestselling brief text uses diverse real-world examples to show students the value of avoiding simplifications in politics, the relevance of government, and the importance of participation. Written from Mike Roskinrs"s unique and engaging point-of-view,Political Scienceremains the best at providing the clear explanations, practical applications, and current examples that will welcome students to a vital field of study.

It is well known that Leibniz advocated the actual infinite, but that he did not admit infinite collections or infinite numbers. But his assimilation of this account to the scholastic notion of the syncategorematic infinite has given rise to controversy. A common interpretation is that in mathematics Leibniz’s syncategorematic infinite is identical with the Aristotelian potential infinite, so that it applies only to ideal entities, and is therefore distinct from the actual infinite that applies to the actual world. Against this, (...) I argue in this paper that Leibniz’s actual infinite, understood syncategorematically, applies to any entities that are actually infinite in multitude, whether numbers, actual parts of matter, or monads. It signifies that there are more of them than can be assigned a number, but that there is no infinite number or collection of them, which notion involves a contradiction. Similarly, to say that a magnitude is actually infinitely small in the syncategorematic sense is to say that no matter how small a magnitude one takes, there is a smaller, but there are no actual infinitesimals. In geometry one may calculate with expressions apparently denoting such entities, on the understanding that they are fictions, standing for variable magnitudes that can be made arbitrarily small, so as to produce demonstrations that there is no error in the resulting expressions. (shrink)

An integrative explanation proposes that culture and gender interact to produce fundamentally different patterns of association between positive and negative emotions. People in independent-based cultures (e.g. the United States) experience emotions in oppositional (i.e. bipolar) ways, whereas people in interdependent-based cultures (e.g. China) experience emotions in dialectic ways. These patterns are stronger for women than men in both cultures. In support of the theory, Study 1 showed that positive and negative emotions are strongly correlated inversely for American women and weakly (...) correlated inversely for American men, but strongly correlated positively for Chinese women and weakly correlated positively for Chinese men. In Study 2, findings for Koreans, although mixed, were closer to the results for Chinese. (shrink)

BackgroundResearchers conducting community-based participatory action research (CBPAR) in highly collectivistic and socioeconomically disadvantaged community settings in sub-Saharan Africa are confronted with the distinctive challenge of balancing universal ethical standards with local standards, where traditional customs or beliefs may conflict with regulatory requirements and ethical guidelines underlying the informed consent (IC) process. The unique ethnic, socioeconomic, and cultural diversities in these settings have important implications for the IC process, such as individual decisional autonomy, beneficence, confidentiality, and signing the IC document.Main textDrawing (...) on insights and field observations from conducting CBPARs across several rural, highly communal, low literate, and low-income communities in Ghana, we discuss some theoretical, ethico-cultural, and methodological challenges associated with applying the universal, Western individualistic cultural value-laden IC process in sub-Saharan Africa. By citing field situations, we discuss how local cultural customs and the socioeconomic adversities prevalent in these settings can influence (and disrupt) the information disclosure process, individual decisional authority for consent, and voluntariness. We review the theoretical assumptions of the Declaration of Helsinki’s statement on IC and discuss its limitations as an ultimate guide for the conduct of social science research in the highly communal African context. We argue that the IC process in these settings should include strategies directed at preventing deception and coercion, in addition to ensuring respect for individual autonomy. We urge Universities, research institutions, and institutional review boards in Africa to design and promote the use of context-appropriate ethical IC guidelines that take into consideration both the local customs and traditional practices of the people as well as the scientific principles underpinning the universal IC standards.ConclusionWe recommend that, rather than adopt a universal one-size-fits-all IC approach, researchers working in the rural, highly collectivistic, low literate, socioeconomically disadvantaged settings of sub-Saharan Africa should deeply consider the roles and influence of cultural values and traditional practices on the IC and the research process. We encourage researchers to collaborate with target communities and stakeholders in the design and implementation of context-appropriate IC to prevent ethics dumping and safeguard the integrity of the research process. (shrink)

Comparative concepts such as greener than or higher than are ways of ordering objects. They are fundamental to our grasp of gradable concepts, that is, the type of meanings expressed by gradable general terms, such as "is green" or "is high", which are embeddable in comparative constructions in natural language. Some comparative concepts seem natural, whereas others seem gerrymandered. The aim of this paper is to outline a theoretical approach to comparative concepts that bears both on the account of naturalness (...) for comparative concepts and on the theory of gradable concepts. The approach is novel in that it carries some basic assumptions from Peter Gärdenfors' conceptual spaces account of categorical concepts over to comparative concepts. The offered approach is more general than Gärdenfors' account in that it supplies a framework of graded categorisation that includes his categorisation rule as a limiting case. Importantly, it provides also a new argument for adopting Gärdenfors' particular model of categorisation. (shrink)

This essay disputes G. A. Cohen's claim that John Rawls's argument for the difference principle involves an argument from moral arbitrariness to equality and then an illicit move away from equality. Moreover, the claim that an argument from moral arbitrariness establishes equality as the essential distributive justice ideal is found wanting.

According to the ideal of tolerance, the state is supposed to be neutral or evenhanded in its dealings with religious sects and doctrines. The tolerant state does not pursue policies aimed at favoring one sect over another.

The essays in this collection examine developments in three fundamental biological disciplines--embryology, evolutionary biology, and genetics--in conflict with each other for much of the twentieth century. They consider key methodological problems and the difficulty of overcoming them. Richard Burian interweaves historical appreciation of the settings within which scientists work, substantial knowledge of the biological problems at stake and the methodological and philosophical issues faced in integrating biological knowledge drawn from disparate sources.

A-LOGIC is a full-length book (600+ pg). It functions as a system of logic designed to: 1) solve the standard paradoxes and major problems of standard mathematical logic; 2) minimize that logic's anomalies with respect to ordinary language, yet; 3) prove that all theorems in mathematical logic are tautologies. It covers lst order logic the logic of the words "and", "or", "not", "all" and "some". But it also has a non truth functional "if...then" and differs in its definition of validity, (...) its semantics and its theorems. In the book A-logic is contrasted step by step with standard mathematical logic as presented and defended by Quine. All of standard logic's theorems are proven tautologies in A-logic. But some argument-forms called "valid" in standard logic are not valid in A-logic -- notably non-sequiturs like "(P and not-P), therefore Q". In addition A-logic has many tautologies with its non-truthfunctional "if ... then" that standard logic can not derive -- e.g., "Not-(if P&Q then not-P)." A-logic's semantics is based on syntactically defined concepts of logical synonymy and containment of meanings rather than on truth-values and truth-functions. Its "if...then" sentences (called "C-conditionals") are valid if and only if (i) the meaning of the consequent is logically contained in that of the antecedent, and (ii) the antecedent and consequent are jointly consistent. The predicate "valid" holds only of C-conditionals and arguments. No valid C-conditionals are translatable into standard logic though all of them imply tautologies of standard logic. (shrink)

An Introduction to the Philosophy of Art is a clear and compact survey of philosophical theories of the nature and value of art, including in its scope literature, painting, sculpture, music, dance, architecture, movies, conceptual art and performance art. This second edition incorporates significant new research on topics including pictorial depiction, musical expression, conceptual art, Hegel, and art and society. Drawing on classical and contemporary philosophy, literary theory and art criticism, Richard Eldridge explores the representational, formal and expressive dimensions (...) of art. He argues that the aesthetic and semantic density of the work, in inviting imaginative exploration, makes works of art cognitively, morally and socially important. This importance is further elaborated in discussions of artistic beauty, originality, imagination and criticism. His accessible study will be invaluable to students of philosophy of art and aesthetics. (shrink)

Is there a moral right to freedom of conscience? Should a legal right to freedom of conscience be established in each country on Earth? This essay argues for negative answers to both questions. The term freedom of conscience might refer to freedom of thought and the freedom of expression that sustains freedom of thought. In this sense we might affirm the right of each person to form individual opinions about the right and the good, about what we owe one another (...) by way of due consideration of others, and about what is worthy of pursuit in life, on the basis of free discussion of these matters. In the present discussion, these freedoms, important as they might be, are not under consideration. Let us assume freedom of thought and expression are secured. The status of freedom of conscience in the sense that is our concern in this discussion is still wide open. (shrink)

Composed of scientific and technical experts and lay members, thousands of research ethics committees—Institutional Review Boards in the United States—must identify and assess the potential risks to human research subjects, and balance those risks against the potential benefits of the research. IRBs handle risk and its uncertainty by adopting a version of the precautionary principle. To assess scientific merit, IRBs use a tacit ``sanguinity principle,'' which treats uncertainty as inevitable, even desirable, in scientific progress. In balancing human subjects risks and (...) scientific benefits, IRBs use uncertainty as a boundary-ordering device that allows the mediation of the science and ethics aspects of their decisions. One effect is the entangling of methodological and ethical review. Some have suggested these should be more clearly separated, but decisions by research ethics committees depend in part on the negotiating space created by incommensurable approaches to uncertainty. (shrink)

This article extends the study of a phenomenological investigation in which six participants wrote protocols and gave interviews describing the experience of being bored with their lives. This study found that the participants gradually became bored after they had compromised their life-projects for less desired projects. The participants felt emotionally ambivalent because they were thematically angry with others involved in their compromises while being pre-reflectively angry with themselves. The participants non-thematically adopted passive and avoidant stances toward their lives that allowed (...) their boredom to spread to more aspects of their lives. The participants' boredom led them to identity issues because they no longer were actively working toward projects. They felt empty and apathetic because they felt every action led to boredom, and thus action was futile. Preliminary distinctions between the experience of life boredom and depression are considered. (shrink)

Several philosophers have questioned the possibility of a genetic epistemology, an epistemology concerned with the developmental transitions between successive states of knowledge in the individual person. Since most arguments against the possibility of a genetic epistemology crucially depend upon a sharp distinction between the genesis of an idea and its justification, I argue that current philosophy of science raises serious questions about the universal validity of this distinction. Then I discuss several senses of the genetic fallacy, indicating which sense of (...) ‘genesis’ is relevant to epistemology. Next I consider the objection that psychology is irrelevant to epistemology, and that since "genetic epistemology" is really psychology, "genetic epistemology" is irrelevant to a real epistemology. Finally, I take up the objection that nothing discovered in genetic psychology could be relevant to a genetic epistemology. These last two arguments are based upon what I claim to be a mistaken notion of the nature of psychology. Suitably interpreted, psychology can assist genetic epistemology precisely in the way that the history of science assists current philosonhv of science. *I owe considerable thanks to Jann Benson, Ken Freeman, Bernie Rollin and Ron Williams for their helpful discussions concerning many of the issues discussed in this paper. I also wish to thank David Hamlyn, John Heil, William Lycan, Harvey Siegel and an anonymous reviewer for their comments and suggestions. It goes without saying that none of these individuals (especially Hamlyn and Siegel) necessarily agree with me. An earlier version of this paper was read at Colorado State University where the audience's comments were beneficial. (shrink)

One pressing question facing Barnes andWilliams is that of which vari- eties of metaphysical indeterminacy can be can accommodated within their framework. In what remains, I shall examine whether their framework can allow that it sometimes metaphysically indeterminate whether an object exists. I shall begin by outlining an argument, due to Theodore Sider, to the conclusion that vague existence is impossible.

Sex chromosomes can differ between species as a result of evolutionary turnover, a process that can be driven by evolution of the sex determination pathway. Canonical models of sex chromosome turnover hypothesize that a new master sex determining gene causes an autosome to become a sex chromosome or an XY chromosome pair to switch to a ZW pair (or vice versa). Here, a novel paradigm for the evolution of sex determination and sex chromosomes is presented, in which there is an (...) evolutionary transition in the master sex determiner, but the X chromosome remains unchanged. There are three documented examples of the novel paradigm, and it is hypothesized that a similar process could happen in a ZW sex chromosome system. Three other taxa are also identified where the novel paradigm may have occurred, and how it could be distinguished from canonical trajectories in these and additional taxa is also described. (shrink)