We surveyed 1005 postdoctoral fellows by questionnaire about ethical matters related to biomedical research and publishing; 33% responded. About 18% of respondents said they had taken a course in research ethics, and about 31% said they had had a course that devoted some time to research ethics. A substantial majority stated willingness to grant other investigators, except competitors, access to their data before publication and to share research materials. Respondents’ opinions about contributions justifying authorship of research papers were mainly consistent (...) but at variance with those of many biomedical journal editors. More than half said they had observed what they considered unethical research practices. To increase the chances of getting a grant funded, 27% said they were willing to select or omit data to improve their results; to make publication of their work more likely or to benefit their career, 15% would select or omit data and 32% would list an undeserving author. Of respondents who thought they had been unfairly denied authorship on a paper, or been listed with or asked to list an undeserving author, 75% said they would be willing to list an undeserving author (P<0.001). Having taken a course dealing with research ethics had no effect on stated willingness to select or omit data or to fabricate data in the future, but was positively associated with willingness to grant undeserved authorship (P<0.04). Although these results do not controvert research demonstrating the effectiveness of ethics courses during professional education, they indicate that the research environment is a powerful component of a trainee’s experience and ethical development. (shrink)

Albert the Great’s theological and exegetical-biblical works often reshape naturalphilosophical doctrines derived from his earlier Aristotelian paraphrases. Accordingly, Albert’s caveats, distinguishing the treatment of topics in physicis and in theologicis, are not abstract disciplinary borderlines but point out to his Dominican students that he will return to crucial matters of the peripatetic paraphrases, recontextualizing them in later works. This article illustrates such interdisciplinary dynamics by analyzing Albert’s commentary on Gen., 1, 20-23, the fifth day of creation, as discussed in STh., (...) II, xi, 60. Albert questions the seeming asymmetry arising from a single element, water, giving rise to two different outcomes: birds for the sublunar sky and reptiles for the earth. The arguments put forth by opponents and Albert’s solution draw upon earlier natural-philosophical works of his, namely De animalibus, De vegetabilibus, and De sensu et sensatu. Notably, Albert reuses his doctrine of humiditates in living bodies and generative processes (such as humidum seminale, humidum vaporativum, humidum spirans, humidum manens). Additionally, Albert analyzes the processes of subtiliatio and digestio, which transform siccum terreum into the matter required for the formation of animate bodies. (shrink)

Levinas' ethical metaphysics opens up a nexus of relationships, in the midst of which God becomes accessible as the counterpart of the justice I render to others. Although Levinas refuses a theorising theology which does violence to God, we attempt in this article nonetheless to glimpse the possibility of a divine threesome which can be articulated in the language of ethical metaphysics. We seek to trace a Trinity, not in Levinas, but with Levinas. We seek to ‘leash God with Levinas.’Thus, (...) we argue the liturgical nature of God. God is utterly ‘for‐the‐other.’ The Father, as utterly self‐diffusive, is ‘for‐the‐Son’, and the Son, as utterly responsive, is ‘for‐the‐Father.’ The divine nature is the ethical reality of ‘for‐the‐other.’ Secondly, this one nature has three distinct hypostases, which need to be understood ethically. The relationship between Father and Son is not the same as the relationship between the Son and the Father. The Father and the Son are the same in that they are essentially ‘for‐the‐other,’ bound by a bond or a Spirit of responsibility. Yet, the Son's relation to the Father is responsive, whereas the Father's relation to the Son is initiative or originary. Thus, there is both an identity yet a non‐identification of Father and Son. Again, since responsibility is the ethical hypostasis of ‘the‐other‐person‐in me,’ we might say that the Father is in the Son and the Son is in the Father , in a non‐identical way, and that it is precisely this perichoresis of the one in the Other which constitutes the hypostasis of each. (shrink)

No more jobs, no more taxes, no more checkbook, no more bills, no more credit cards, no more credit, no more money, no more mortgages, no more rent, no more savings, no more junk mail, no more junk, no more mail, no more phones, no more faxes, no more busy signals, no more computers, no more cars, no more drivers' licenses, no more traffic lights, no more airports, no more flying, no more tickets, no more packing, no more luggage, no (...) more supermarkets, no more health clubs...While her "current" spends the summer researching public housing in Stockholm, a moderately wealthy, object-oppressed, and terminally hip New York female of a certain age seeks adventure in the sedate dyke bars of lower Manhattan. Finding none, she answers a personal ad. She is ordered to put on a blindfold before the first meeting with the woman she knows only as "Sir." Not knowing what someone looks like turns out to be freeing, as do the escalating constraints that alienate her not just from her former life, but from her very conception of who she is. Part Georges Bataille, part Fran Leibowitz, this is the Story of O told with a self-referentially perverse sense of humor. Leash extends the logic of S&M to its inexorable and startling conclusion, darkly and hilariously revealing the masochistic impulse as the urge to disappear from the chores, obligations, and emotional vacuity of daily life. First published in 2002. (shrink)

New perspectives on the role of collective responsibility in modern politics States are commonly blamed for wars, called on to apologize, held liable for debts and reparations, bound by treaties, and punished with sanctions. But what does it mean to hold a state responsible as opposed to a government, a nation, or an individual leader? Under what circumstances should we assign responsibility to states rather than individuals? Leviathan on a Leash demystifies the phenomenon of state responsibility and explains why it (...) is a challenging yet indispensable part of modern politics. Taking Thomas Hobbes' theory of the state as his starting point, Sean Fleming presents a theory of state responsibility that sheds new light on sovereign debt, historical reparations, treaty obligations, and economic sanctions. Along the way, he overturns longstanding interpretations of Hobbes' political thought, explores how new technologies will alter the practice of state responsibility as we know it, and develops new accounts of political authority, representation, and legitimacy. He argues that Hobbes' idea of the state offers a far richer and more realistic conception of state responsibility than the theories prevalent today, and demonstrates that Hobbes' Leviathan is much more than an anthropomorphic "artificial man." Leviathan on a Leash is essential reading for political theorists, scholars of international relations, international lawyers, and philosophers. This groundbreaking book recovers a forgotten understanding of state personality in Hobbes' thought and shows how to apply it to the world of imperfect states in which we live. (shrink)

Human personality influences the way people interact with dogs. This study investigated the associations between the personality of animal shelter volunteers and behavior during on-leash walks with shelter dogs. Video recording and a canine leash tension meter were used to monitor the on-leash walking. Personality was measured in five dimensions with the NEO Five-Factor Inventory. Neurotic volunteers pulled the leash harder and tended to interact with dogs using more body language; dogs being walked by neurotic volunteers in turn displayed more (...) lip-licking and body shaking and were more likely to be rated as well-behaved. Extroverted volunteers were associated with stronger maximal leash tension at both the human and dog ends of the leash, and they praised the dog more, often in a high pitched voice. These volunteers eliciting more tail-wagging and body shaking by the dog. Extroverted volunteers were also more tolerant of different dog behaviors. Volunteers with personalities characterized by “openness to experiences” were less likely to verbally attract the attention of dogs, praise dogs and talk to them in a high-pitched voice; however, dogs walked by these volunteers were more likely to pull on the leash, and engaged in more lip-licking but less sniffing. “Agreeable” volunteers liked to verbally attract the attention of the dogs and more commonly initiated hand gestures and physical contact, causing the dogs to pull less frequently; dogs in these dyads displayed more gazing and lip-licking behaviors. Conscientious volunteers were less likely to pull the leash and tended to have more physical contact with the dogs but did not favor verbal communication and did not use a high pitched voice. (shrink)

The trade in, and private keeping of, reptiles as "pets" raises several ethical concerns regarding animal welfare (associated with handling, storage, transportation, intensive captive breeding, captivity stress, injury, disease, and high premature mortality); public health and safety (associated with zoonotic disease and animal-linked injuries); species conservation and environmental degradation (associated with wild capture); and ecological alteration (associated with invasive alien species). Also, many captive reptiles are fed other animals, raising broader ethical questions. Misperceptions about reptiles by proponents of their captivity (...) mean that these animals are subject to conditions that would likely be considered unacceptable for dogs or cats. (shrink)

Early modern theorists linked the idea of sovereign power to a conception of absolute power developed during the medieval period. Ockham had reframed the already extant distinction between God's absolute and ordained powers in order to argue that God was free of moral constraint in ordaining natural law for human beings. Thus, the natural law could command the opposite of what God had ordained if He wished to make it so. Bodin extended Ockham's argument to earthly sovereigns, who do not (...) (he argued) have to obey civil law. However, Bodin undermined his absolutism by maintaining that civil law has to be consistent with natural and divine law. Hobbes more consistently argued that while mortal sovereigns are accountable to God, the power of sovereigns to command is not subject to moral constraints. Underlying Ockham's view of God's sovereignty, and Bodin's and Hobbes's view of earthly sovereigns, is a notion of the will's unconstrained power. But this notion is self-referentially incoherent. This incoherence, in turn, infects the very notion of sovereignty. (shrink)

In many species of reptiles, sex is determined at fertilization by zygotic sex chromosome composition. In other species, including all crocodilians, most turtles and some lizards, sex is determined by temperature during the earlier stages of gonadal differentiation. The effects of exogenous estrogens, antiestrogens and aromatase inhibitors at different temperatures have unambiguously demonstrated the involvement of estrogens in sexual differentiation of the gonads. Aromatase is the enzyme that converts androgens to estrogens. Gonadal aromatase activity is well correlated with gonadal structure. (...) It increases exponentially in differentiating ovaries, whereas it remains low in differentiating testes. Moreover, there is a high correlation between the thermosensitive periods for both ovary differentiation and increase in aromatase activity. We suggest that a thermosensitive factor intervenes, directly or indirectly, in the transcriptional regulation of the aromatase gene in reptiles with temperature‐dependent sex determination. (shrink)

Late antique political Platonism was not unoriginal in its thought. The paper takes as an example the Justinianic dialogue On Political Science (ca. 550), which creatively engages with Plato’s political works. It shows that the dialogue tries – and manages, as I argue – to combine two apparently inconsistent Platonic models: what I call the “divine” model, in which a philosopher-king endowed with divine knowledge rules unhindered by civic laws; and the “human” model, characterized by the rule of law. The (...) divine model comes mostly from Plato’s Republic and Statesman; the human one, from the Laws. On Political Science demonstrates that its (anonymous) author was acquainted with these three Platonic texts, in addition to other texts. That is philologically noteworthy, but also philosophically interesting: the dialogue manages to integrate the two models into a common framework. It puts forward an original political model, in which a philosopher-king, although endowed with divine knowledge, still has to be bound by civic laws because of his human frailty. The article concludes by discussing the polemical import the dialogue could have had in its Justinianic context. (shrink)

We use screams to explore ideas presented in the target article. Evolving first in animals as a response to predation, screams reveal more complex social use in nonhuman primates and, in humans, uniquely, are associated with a much greater variety of emotional contexts including fear, anger, surprise, and happiness. This expansion, and the potential for manipulation, promotes listener social vigilance.

Tras intentar definir el género gótico, el artículo se centrará en las características generales de la obra narrativa de Pilar Pedraza, representante de dicho género en la literatura española actual. Después se hará un breve análisis de sus novelas.

This paper examines the first reptile house (1849) at the Zoological Gardens in London as a novel site for the production and consumption of knowledge about snakes, stressing the significance of architectural and material limitations on both snakes and humans. Snakes were familiar and ambiguous, present at every level of British society through the reading of Scripture and as recurrent characters in imperial print culture. For all that snakes engendered feelings of disgust as the most distinctive representatives of a (...) lowly class of animals, they exerted an equivalent fascination over diverse publics spanning the social spectrum. Building on work showing a consideration for the multi-sensory nature of visits to menageries, this paper considers animal display beyond the visual. It explores the emotional economy of encountering snakes in person and the bodily phenomena this engendered. Vicarious visits were offered up to readers of periodicals and newspapers and the reptile house was harnessed as a controversial pedagogical resource for teaching moral, as well as scientific, lessons. (shrink)

Two prevailing paradigms explain the diversity of sex-determining modes in reptiles. Many researchers, particularly those who study reptiles, consider genetic and environmental sex-determining mechanisms to be fundamentally different, and that one can be demonstrated experimentally to the exclusion of the other. Other researchers, principally those who take a broader taxonomic perspective, argue that no clear boundaries exist between them. Indeed, we argue that genetic and environmental sex determination in reptiles should be seen as a continuum of states represented by species (...) whose sex is determined primarily by genotype, species where genetic and environmental mechanisms coexist and interact in lesser or greater measure to bring about sex phenotypes, and species where sex is determined primarily by environment. To do otherwise limits the scope of investigations into the transition between the two and reduces opportunities to use studies of reptiles to advance understanding of vertebrate sex determination generally. © 2004 Wiley Periodicals, Inc. (shrink)

Since his death in 2003 at the age of fifty-six, Warren Zevon’s following has grown, and seven books on Zevon have appeared in the last few years, with more in the works. The Zevon legend continues to attract attention both because of the outstanding quality of his best songs and because of the poignant trajectory of his life. Zevon’s descent into alcoholism and other addictions, along with his debauchery and erratic behaviour, took its toll and his performances suffered, an aspect (...) disturbingly captured in the memoir by his ex-wife Crystal Zevon. This collection of chapters on Zevon’s life and music, authored by philosophers who are also Zevon fans, will provide new and exciting insights into Zevon’s thinking, his cynical lyrics, and the cruel ironies of his roller-coaster life and career. (shrink)

Unlike birds and mammals, reptiles are commonly thought to possess only the most rudimentary means of interacting with their environments, reflexively responding to sensory information to the near exclusion of higher cognitive function. However, reptilian brains, though structurally somewhat different from those of mammals and birds, use many of the same cellular and molecular processes to support complex behaviors in homologous brain regions. Here, the neurological mechanisms supporting reptilian cognition are reviewed, focusing specifically on spatial cognition and the hippocampus. These (...) processes are compared to those seen in mammals and birds within an ecologically and evolutionarily relevant context. By viewing reptilian cognition through an integrative framework, a more robust understanding of reptile cognition is gleaned. Doing so yields a broader view of the evolutionarily conserved molecular and cellular mechanisms that underlie cognitive function and a better understanding of the factors that led to the evolution of complex cognition. (shrink)