Explanation in biology has long been characterized as being very different from explanation in other scientific disciplines, very much so from explanation in physics. One of the reasons was the existence in biology of explanation types that were unheard of in the physical sciences: teleological explanations (e.g. Hull 1974), evolutionary explanations (e.g. Mayr 1988), or even functional explanations (e.g. Neander 1991). More recently, and owing much to the rise of molecular biology, biological explanations have been depicted as mechanisms (e.g; Machamer, (...) Darden and Craver 2000). The aim of this volume is to shed some new light on the diversity of explanation types in biology. What are the different types of explanation that occur in biology? Are these types of explanation specific to particular sub-disciplines of biology, or to particular types of problems across biology? How do they relate to each another? Do they compete with one another for answering the same questions? Or do they complement each other, providing insights to different questions? What are the reasons for such diversity? Can this diversity be overcome by a broader unifying model of explanation or is it more profound and irreducible? Why? This volume aims at making sense of this diversity of types of explanations that are found in biology, of their relationship with one another. After all, explanation in biology may prove not only different from explanation in the physical sciences, but also much more diverse than originally anticipated. (shrink)

Dans Science, Perception and Reality, Sellars distingue l’image manifeste de l’homme et l’image scientifique de l’homme. La première est obtenue à partir de la façon dont nous prenons conscience de nous-mêmes comme humains dans le monde. La seconde correspond à ce que les différentes sciences nous amènent à postuler sur la manière dont l’homme est constitué. Van Fraassen, lui, étend au monde ces concepts...

November 4th-5th, 2012 at Kyoto University. Organizers: Hisashi Nakao & Pierre-Alain Braillard.

Technology and Ethics. A European Quest for Responsible Engineering, edited by B. Heriard Dubreuil and his team (University Lille) is in many regards an innovative publication. It is the first fully European contribution to the field of engineering ethics and the result of an intensive cooperation between ethicists and engineers from all the member countries of the European Union. The basic structure of the book is both the distinction and interaction between three levels of analysis: personal responsibility of engineers, the (...) institutional level (business organisations) and the impact of technology on society and culture. On the personal level, the book deals with problems such as the role of professional codes and the fact that engineers must cope with flexibility, shorter lines of decision and erosion of the boundaries between private and professional life. On the meso level, the book deals with different aspects of decision making in the context of business organizations, such as quality management, technology assessment procedures, business ethics committees etc... On the macro level, the authors focus on the power of technology. Together with the influences from other social, economic and political actors, the decisions of engineers change the world in a way which is of moral significance. (shrink)

We investigate two formalizations of Optimality Theory, a successful paradigm in linguistics.We first give an order-theoretic counterpart for the data and processinvolved in candidate evaluation.Basically, we represent each constraint as a function that assigns every candidate a degree of violation.As for the second formalization, we define (after Samek-Lodovici and Prince) constraints as operations that select the best candidates out of a set of candidates.We prove that these two formalizations are equivalent (accordingly, there is no loss of generality with using violation (...) marks and dispensing with them is only apparent).Importantly, we show that the second formalization is equivalent with a class of operations over sets of formulas in a given logical language.As a result, we prove that Optimality Theory can be characterized by certain cumulative logics.So, applying Optimality Theory is shown to be reasoning by the rules of cumulative logics. (shrink)

Rationale, aims and objectives This randomized controlled trial was designed to evaluate the 2-year costs and effects of a proactive, public health nursing case management approach compared with a self-directed approach for 129 single parents (98% were mothers) on social assistance in a Canadian setting. A total of 43% of these parents had a major depressive disorder and 38% had two or three other health conditions at baseline. Methods Study participants were recruited over a 12 month period and randomized into (...) two groups: one receiving proactive public health nursing and one which did not. Results At 2 years, 69 single parents with 123 children receiving proactive public health nursing (compared with 60 parents with 91 children who did not receive public health nursing services) showed a slightly greater reduction in dysthymia and slightly higher social adjustment. There was no difference between the public health and control groups in total per parent annual cost of health and support services. However, costs were averted due to a 12% difference in non-use of social assistance in the previous 12 months for parents in the public health nursing group. This translates into an annual cost saving of $240 000 (Canadian) of costs averted within 1 year for every 100 parents. Conclusions In the context of a system of national health and social insurance, this study supports the fact that it is no more costly to proactively service this population of parents on social assistance. (shrink)

Standard quantum theory is inadequate to explain the mechanisms by which potential becomes actual. It is inadequate and therefore unable to describe generation of events. Niels Bohr emphasized long ago that the classical part of the world is necessary. John Bell stressed the same point: that “measurement≓ cannot even be defined within the standard quantum theory, and he sought a solution within hidden variable theories and his concept of “beables.≓Today it is customary to try to explain emergence of the classical (...) world through a decoherence mechanism due to “environment.≓ But, we believe, as it was with the concept of measurement, “environment≓ itself cannot be defined within the standard quantum theory.We have proposed a semiphenomenological solution to this problem by introducing explicitly, from the very beginning, classical degrees of freedom, and by coupling these degrees of freedom, through a Lindblad type coupling, to the quantum world. The resulting theory, we call “event-enhanced quantum theory.≓ EEQT allows us to describe an event-generating mechanism for individual quantum systems under continuous observation. The objections of John Bell are met and precise definitions of an “experiment≓ and of a “measurement≓ have been given within EEQT. However EEQT is, essentially, a nonrelativistic theory.In the present paper we extend the ideas of L. P. Horwitz and C. Piron and we propose a relativistic version of EEQT, with an event-generating algorithm for spin one-half particle detectors. The algorithm is based on proper time formulation of the relalivistic quantum theory. Although we use indefinite metric, all the probabilities controlling the random process of the detector clicks are nonnegative. (shrink)

Dogmatic Metaphysics and Tschirnhaus's M ethodology MARTIN SCHONFELD ACCORDING TO STANDARD COMMENTARIES, Tschirnhaus's main work, Medicina mentis, ~ supposedly furnished the methodological basis for the Leibnizian-Wolffian metaphysics. ~ Christian Wolff and his disciples, at any rate, preferred to think so. Wolff taught classes on Tschirnhaus and claimed that he had developed his own tenets on the basis of Tschirnhaus's ideas; Johann Christoph Gottsched praised the Medicina mentis as the basic methodology of the Wolffian enlightenment.3 Mirroring these views, W. Wundt and (...) H. J. de Vleeschauwer saw in Tschirnhaus the inventor of the "geometric method" adopted by the School Philosophers.4 According to M. ' Medicina Mentis, sive Tentamen genuinae Logicae, in qua disseritur de Methodo detegendi incoKaitas veritates, Amsterdam, 1687. Second and revised edition, Medicina Mentis, sive Artis inveniendi Praecepta generalia, Leipzig, 1695. ~For example, cf. Wilhelm Windelband, Geschichte der Philosophie, 3~o-33 and 356; Friedrich Ueberweg, Grundriss der Geschichte der Philosophie, III: ~95-97, 3 x~ 34o-43; A. Robert Caponigri, A History of Western Philosophy (Notre Dame/London: University of Notre Dame.. (shrink)