Many viruses evolved mechanisms for capping the 5′‐ends of their plus‐strand RNAs as a means of hijacking the eukaryotic messenger RNA (mRNA) splicing/translation machinery. Although capping is critical for replication, the RNAs of these viruses have other essential functions including their requirement to be packaged as either genomes or pre‐genomes into progeny viruses. Recent studies indicate that human immunodeficiency virus type‐1 (HIV‐1) RNAs are segregated between splicing/translation and packaging functions by a mechanism that involves structural sequestration of the 5′‐cap. Here, (...) we examined studies reported for other viruses and retrotransposons that require both selective packaging of their RNAs and 5′‐RNA capping for host‐mediated translation. Our findings suggest that viruses and retrotransposons have evolved multiple mechanisms to control 5′‐cap accessibility, consistent with the hypothesis that removal or sequestration of the 5′ cap enables packageable RNAs to avoid capture by the cellular RNA processing and translation machinery. (shrink)

ObjectivesTo simulate hemodynamic changes after extraluminal compression in pulsatile tinnitus patients with a prominent transverse-sigmoid sinus junction.MethodsOne patient-specific case was reconstructed based on computed tomography venography images of a PT patient. The compression degree served as a new index in this study. Cases with 10, 20, 30, 40, 50, 60, 70, 80, and 90% of the compression degree of the control subject were constructed. Steady-state computational fluid dynamics were assessed. The wall pressure distribution, wall maximum pressure and flow pattern of (...) the PTSJ were calculated to evaluate hemodynamic differences among all cases.ResultsWith increasing compression, the wall pressure at the compression point and downstream of the PTSJ decreased but increased upstream. When the compression degree exceeded 70%, the upstream pressure increased significantly. Above 50% compression, the blood flow pattern downstream of the sigmoid sinus tended to spiral, especially after 80% compression. Beyond 60% compression, the blood flow pattern under the compression axis became more medial.ConclusionMechanical compression of PTSJ changes wall pressure and blood flow patterns. The degree of compression should be carefully observed to avoid possible complications or reoccurrence. (shrink)

Relevant research shows teachers’ “psychological power” plays a more essential role in promoting their professional development compared with the powers provided by various external factors, and it is therefore held that exploring college English teachers’ individual psychological power is of great significance. To this end, this study investigated college English teachers’ psychological empowerment via the development and validation of CETPE’s scale. Based on our literature review on psychological empowerment and analysis of teachers professional development’s status quo, we made a working (...) definition of CETPE as a system involving perception of their occupation, sense of competence, experiencing of autonomy, judgment of their impact and understanding of their status. In our study, firstly the literature review and the interview with 17 college English teachers were adopted to conceptualize the dimensions of CETPE, and an exploratory factor analysis of data was conducted from 227 college English teachers and then the subsequent confirmatory factor analysis of data collected from another sample of 1030 generated 15 items belonging to five factors. The findings reveal that CETPE is systematically composed of teachers’ positive perception and experience of work meaningfulness, teaching autonomy, occupational competence, professional impact and social status. This study provides a new path for teachers’ professional development via strengthening their intrinsic driving force and thus helps improve the college English teaching effects. (shrink)

In this paper, we mainly investigate the existence of states based on the Glivenko theorem in bounded semihoops, which are building blocks for the algebraic semantics for relevant fuzzy logics. First, we extend algebraic formulations of the Glivenko theorem to bounded semihoops and give some characterizations of Glivenko semihoops and regular semihoops. The category of regular semihoops is a reflective subcategory of the category of Glivenko semihoops. Moreover, by means of the negative translation term, we characterize the Glivenko variety. Then (...) we show that the regular semihoop of regular elements of a free algebra in the variety of Glivenko semihoops is free in the corresponding variety of regular semihoops. Similar results are derived for the semihoop of dense elements of free Glivenko semihoops. Finally, we give a purely algebraic method to check the existence of states on Glivenko semihoops. In particular, we prove that a bounded semihoop has Bosbach states if and only if it has a divisible filter, and a bounded semihoop has Riečan states if and only if it has a semi-divisible filter. (shrink)

Despite increasing interest being given to dysfunctional customer behavior in multiple service sectors, it is unclear how and why different types of dysfunctional customer behavior affect frontline employees’ emotional labor during the service interactions. Drawing upon the conservation of resources theory, we propose a conceptual model in which verbal abuse, disproportionate demand, and illegitimate complaint differentially influence frontline employees’ emotional labor strategies. Further, the boundary conditions of these relationships are considered by introducing perceived organizational support and customer orientation as moderators. (...) Using survey data from 436 frontline employees of five call centers in China, hypotheses were tested through a hierarchical regression analysis. The results indicated that verbal abuse and illegitimate complaint exerted positive effects on surface acting. Particularly, these positive effects were weaker when frontline employees perceived organizational support was high. Also, verbal abuse’s positive effect on surface acting was weaker when frontline employees’ customer orientation was high. Customer’s verbal abuse, disproportionate demand, and illegitimate complaint negatively influenced frontline employees’ deep acting. The negative effect of disproportionate demand on deep acting was weaker when perceived organizational support was high. However, when frontline employees’ customer orientation was high, the negative effects of disproportionate demand and illegitimate complaints on deep acting were weaker. (shrink)

Anticipation is a crucial perceptual-cognitive skill in fast-ball sports, and the effect of high anxiety on performance has attracted more attention from sports psychologists. Related studies mainly focus on the effect of anxiety on influencing processing efficiency and attentional control during information processing in sport. Attentional Control Theory has been supported by several studies. However, these studies have been criticized by the low ecological validity of task design, such as neglecting the dynamic process of anticipation, and inadequate performance analysis, such (...) as analyzing response accuracy and time separately. Using temporal occlusion paradigm, we tested ACT in a dynamic anticipation process. Eighteen skilled and eighteen less-skilled table tennis players were required to anticipate the serves of opponents under dynamic task constraints and anxiety conditions. High cognitive state anxiety decreased processing efficiency for both groups whereas performance effectiveness did not differ. In addition, it negatively affected processing efficiency in early anticipation compared with late anticipation tasks, suggesting that high cognitive state anxiety may have a greater impact on top-down attentional control. Our findings provide support for ACT and show that anxiety impairs anticipation efficiency and performance, possibly due to an ineffectively attentional shift from external kinematic cues to internal long-term working memory. Findings also have implications for the adaptation of attentional strategies and anxiolytic training. (shrink)

This paper proposes a minimal logic of fine-grained information dynamics via belief bases. The framework is shown to be able to accommodate explicit belief, implicit belief, awareness of and awareness that, where awareness of agents is not treated as a tacit premise. A sound and complete axiomatization of static logic is established, upon which a series of dynamic operations are defined. It is argued that these dynamics adapt different scenarios. Our logic is minimal because to each agent we only attach (...) two databases, from which a variety of epistemic attitudes are generated. (shrink)

Compared with traditional technological innovation modes, green technology innovation is more targeted for low carbon development and critical support for countries worldwide to combat climate change. The impact of green technology innovation on carbon emissions is considered in terms of fixed effect and mediating effect models through industrial structure upgrading. For this purpose, the sample dataset of 30 provincial administrative areas in China from 2008 to 2020 is employed. The results demonstrate that green technology innovation exerts significantly inhibitory effects on (...) carbon emissions, whose conclusion still holds after removing municipalities and replacing the dependent variable. Industrial structure upgrading is vital for green technology innovation to diminish carbon emissions. There is significant regional heterogeneity in the effects of green technology innovation on carbon emissions, i.e., the direct and indirect impact of green technology innovation on carbon emission reduction is significant in the eastern-central area, but its effect is insignificant in the western region. Therefore, it is essential to realize carbon emission reduction by further bolstering green technology innovation and accelerating industrial structure upgrading to fulfill the synergy of technology and structure. (shrink)

The understanding of food cue associated neural activations that predict future weight variability may guide the design of effective prevention programs and treatments for overeating and obesity. The current study investigated the association between brain response to different food odors with varied energy density and individual changes of body mass index (BMI) over two years. Twenty-five participants received high-fat (chocolate and peanut), low-fat (bread and peach) food odors and a nonfood odor (rose) while the brain activation was measured using functional (...) magnetic resonance imaging (fMRI). BMIs were calculated with participant’s self-reported body weight and height collected at the time of fMRI scan and again at two years later. Regression analyses revealed significant negative correlations between BMI increase over 2 years and brain activation of the bilateral precuneus and the right posterior cingulate cortex in response to high-fat versus low-fat food odors. In addition, brain activation of the right supplementary motor area in response to food vs non-food odor was negatively correlated to subsequent BMI increase over 2 years. Taken together, the current findings suggest that individual differences in neural responsivity to (high calorie) food odors in brain regions of the default mode and motor control network serve as a neural marker for future BMI change. (shrink)

With the idea of analyzing awareness as potential for knowledge, we propose a novel semantics for awareness logic. Expressivities of languages with different combinations of modalities for this semantics are investigated. We explore the properties of our semantics and compare our model with Fagin & Halpern model and the model by Heifetz et al. in partitional settings. A series of equivalence results are established from the comparison. Finally, we provide two axiomatizations for implicit knowledge and explicit knowledge, respectively, and prove (...) soundness and completeness for them. (shrink)

This book explores how one can bring about changes in the brain through meditation, both through attention-focus training and through compassion training. Recent findings in the natural sciences have confirmed that it is possible for humans to achieve these structural and functional changes through various life-style practices. It is argued that meditation enables us to influence some aspects of our biological make-up and, for example, could boost our cognitive flexibility as well as our ability to act compassionate. Such changes are (...) likely to facilitate the instilling of a number of epistemic virtues which have great bearing on our quality of life. This book offers the reader an accessible introduction to a set of neuro-enhancement methods, with a special focus on meditation techniques, and explores how such practices could contribute to make us better decision-makers and improve our moral virtues. The book is suitable for anyone looking for a text discussing the effects of neuro-enhancement from a secular ethics perspective. (shrink)

Moderate pragmatic invariantism (MPI) is a proposal to explain why our intuitions about the truth-value of knowledge claims vary with stakes and salient error-possibilities. The basic idea is that this variation is due to a variation not in the propositions expressed (as epistemic contextualists would have it) but in the propositions conversationally implicated. I will argue that MPI is mistaken: I will distinguish two kinds of implicature, namely, additive and substitutional implicatures. I will then argue, first, that the proponent of (...) MPI cannot appeal to additive implicatures because they don’t affect truth-value intuitions in the required way. Second, I will argue that the proponent of MPI cannot appeal to substitutional implicatures either because, even though they may have the required effects on truth-value intuitions, they don’t feature in the relevant cases. It follows that MPI is mistaken because whether the proponent of MPI appeals to additive or substitutional implicatures, at least one of the claims that make up her view is false. Along the way, I will suggest principles about implicatures that should be relevant not only to MPI, but to pragmatic accounts of seemingly semantic intuitions in general. (shrink)

EDITOR’S ABSTRACTThe popular Chinese portrayal of the victory of Confucianism, or in Chinese terms “dismiss the hundred schools of thought and revere only the Confucian arts,” has been challenged by some scholars in the past decades. Ding’s essay illustrates not only how it has been challenged but also how the catch phrase influences the scholarly discussion. As he indicates, recent Chinese studies that attempt to subvert the traditional theory share the same “flow.” They fail to note that the expression (...) “dismiss the hundred schools of thought and revere only the Confucian arts” has had very negative connotations since it was invoked by Yi Baisha 易白沙 to harshly denounce Confucianism for being responsible for the centuries-long Chinese autocracy. (shrink)

In The Rise of Modern Chinese Thought (2023), Wang Hui unfolds two interrelated threads to help us understand China’s historical transition from the pre-modern to modernity. The first thread reveals institutional change in the socio-political realm, tracing the transition from a society based on enfeoffment (fengjian zhi) in the pre-Qin period, to an empire characterized by centralized administration (junxian zhi) during the Tang–Song eras, and eventually to the modern society that began to emerge in the late Qing period. The second (...) thread concerns the paradigm shift in the intellectual realm, with particular emphasis on moral (including social and political) philosophy—or "worldview" in Wang’s terms. This shift moves from the worldview of the rites and music (liyue), to the worldview of heavenly principle (tianli), and finally to the worldview of universal principle (gongli). This essay reframes Wang’s rich depiction of China’s intellectual history through the evolving relationship between the concepts of "principle" (li) and "things" (wu). Based on Wang’s work, it identifies three fundamental stances of Chinese moral philosophy and suggests the possibility of a fourth kind. (shrink)

This paper presents a novel understanding of the notion of calculability. In Gricean frameworks, calculability is defined in terms of how speakers can infer an implicature. The relevant inferences must e.g. be based on maxims of conversation or cooperation principles. Meanwhile, I suggest to define calculability in terms of when, or under which conditions, speakers can infer an implicature. An implicature is calculable if hearers can infer its existence even supposing that the implicature is not semantically encoded. This approach avoids (...) familiar challenges, including recently prominent challenges from pragmatic particularism. (shrink)

This article brings together two sets of data that are rarely discussed in concert; namely, disagreement and testimony data. I will argue that relativism yields a much more elegant account of these data than its major rival, contextualism. The basic idea will be that contextualists can account for disagreement data only by adopting principles that preclude a simple account of testimony data. I will conclude that, other things being equal, we should prefer relativism to contextualism. In making this comparative point, (...) I will also defend self-standing relativist accounts of disagreement and testimony data. (shrink)

This book shows how pressing issues in bioethics – e.g. the ownership of biological material and human cognitive enhancement – successfully can be discussed with in a virtue ethics framework. This is not intended as a complete or exegetic account of virtue ethics. Rather, the aim here is to discuss how some key ideas in Aristotle’s Nicomachean Ethics, when interpreted pragmatically, can be a productive way to approach some hot issues in bioethics. In spite of being a very promising theoretical (...) perspective virtue ethics has so far been underdeveloped both in bioethics and neuroethics and most discussions have been conducted in consequentialist and/or deontological terms. ​. (shrink)

In “History of the Lie: Prolegomena,” Derrida criticizes Arendt’s commitment to the “great resiliency” of factual truth against all lies in her essay “Truth and Politics,” claiming that she reintroduces a teleological account of history that clashes with her anti-totalitarian and anti-systematic thinking. By focussing on her understanding of truth-telling as action, this article shows that Arendt does not turn truth into a permanently stable ground for politics. Instead, Arendt’s theory of self-deception constitutes a lie capable of ending all truth. (...) Set in opposition to the nihilism of self-deception, Arendt understands truth-telling as an exemplary act that preserves the possibility of truthfulness and future actions. (shrink)

This study examines the effects of corporate social responsibility (CSR) performance of Chinese firms on the formation of cross-border alliances with partners in developed countries. We use signaling theory and the co-evolutionary perspective as bases in proposing that the signaling effects of CSR performance on cross-border alliance formation are subject to the influences of subnational, national, and cross-national institutions. By using a longitudinal data set, we find that the signaling effects of CSR performance on cross-border alliance formation emerged only after (...) a national system of CSR-related institutions had been established. Once this framework was set up, the effectiveness of CSR as a signal was subject to subnational (intra-country) and cross-national (inter-countries) institutional differences. We conclude that combining signaling theory with the co-evolutionary perspective contributes to CSR research in emerging markets. (shrink)

Wireless devices consume large amounts of energy during wireless communication. As the energy storage of battery is limited, improving energy efficiency has become an important approach to prolong the lifetime of devices. The IEEE 802.11 protocol supports the power save mode in wireless local area networks. However, the standard PSM cannot adapt to the changes of traffic load or channel conditions. Therefore, this article proposes an adaptive traffic-aware PSM mechanism that improves energy efficiency of wireless devices in a WLAN with (...) an access point. According to the current channel condition and traffic load, the AP adjusts the interval of beacons that give devices different priorities to fetch buffered packets. The devices can adaptively adjust listening intervals according to network traffic, and adopt different congestion backoff timers when channel collisions happen or the network topology changes. The APSM has been implemented and evaluated in NS-2. The simulation results have shown that devices using the APSM can improve energy efficiency by 115% at most compared with the ones using the standard PSM. The benefit of adaptive beacon interval and listening intervals is significant, while the improvement due to the adaptive backoff timer is minor. The improvement of the APSM over the PSM is more significant when the network traffic level decreases and the ratio of idle power to sleeping power increases. Additionally, the APSM increases the delay of data frames within a limited range, which does not bring any bad effect on network throughput. (shrink)

In this paper, we study the path based continuous spatial keyword queries, which find the answer set continuously when the query point moves on a given path. Under this setting, we explore two primitive spatial keyword queries, namely k nearest neighbor query and range query. The technical challenges lie in that: retrieving qualified vertices in large road networks efficiently, and issuing the query continuously for points on the path, which turns out to be inapplicable. To overcome the above challenges, we (...) first propose a backbone road network index structure, which supports the distance computation efficiently and offers a global insights of the whole road network. Motivated by the safe zone technique, we then transform our queries to the issue of finding event points, which capture the changes of answer set. By this transformation, our queries are to be simple and feasible. To answer the queries, we propose a Two-Phase Progressive computing framework, which first computes the answer sets for some crucial vertices on the path, and then identifies the event points by the retrieved answer sets. Extensive experiments on both real and synthetic data sets are conducted to evaluate the performance of our proposed algorithms, and the results show that our algorithms outperform competitors by several orders of magnitude. (shrink)

ABSTRACTThree experiments examined how people reason about what is possible or necessary when a conditional is true. Participants were asked to indicate whether it was necessary, possible or impossible for a specific instance to conform to one of the truth-table cases, given the truth of the conditional. It was found that most participants, inconsistently, judged the pq case as necessary but the ¬pq or ¬p¬q cases as possible. Logically, these two kinds of judgments are contradictory. Moreover, a true conditional doesn’t (...) imply that a specific instance under the conditional must be pq. Therefore, people demonstrate a necessity illusion for pq cases which contradicts their commitment to the possibility of ¬pq or ¬p¬q cases. Existing accounts of conditionals are unable to explain the contradiction and the necessity illusion. We propose an inference dissociation account and explore the theoretical implications of this necessity illusion. (shrink)

Given a Polish group G, let $E(G)$ be the right coset equivalence relation $G^{\omega }/c(G)$, where $c(G)$ is the group of all convergent sequences in G. The connected component of the identity of a Polish group G is denoted by $G_0$. Let $G,H$ be locally compact abelian Polish groups. If $E(G)\leq _B E(H)$, then there is a continuous homomorphism $S:G_0\rightarrow H_0$ such that $\ker (S)$ is non-archimedean. The converse is also true when G is connected and compact. For $n\in {\mathbb (...) {N}}^+$, the partially ordered set $P(\omega )/\mbox {Fin}$ can be embedded into Borel equivalence relations between $E({\mathbb {R}}^n)$ and $E({\mathbb {T}}^n)$. (shrink)

Ferdinand de Saussure and Charles Sanders Peirce are two founding fathers of modern semiotics but, up until fairly recently, their theories have fared differentlyon the mainland of China, with the former canonized in university textbooks and the latter banished from academic discussion for political reasons. What this article tries to show is that, thanks to its picto-phonetic origin, the Chinese language lends itself particularly well to theorization from the Peircean perspective, hence the importance of embracing his trichotomous approach to language (...) and other types of signs. (shrink)

Based on the assumption that the long-term value of a venture capital satisfies the algebraic Brownian motion, we develop a continuous-time exit model of venture capital under different exit modes, namely, initial public offering and mergers and acquisitions. The employee incentive problem is analyzed jointly with the exit decision of the firm in terms of the exit timing and the exit mode. Further, the problem of capital exit is considered from two perspectives, namely, optimal venture capital and social welfare maximization, (...) and the differences between these exit decisions are compared. Our model predicts that the timing of an IPO, the purpose of which is to maximize the utility of the capitalists, lags behind the exit timing, whose purpose is to maximize social welfare. Using a numerical analysis, this paper also proves that increasing the production efficiency, lowering the interest rates, and improving risk management can make the exit decision of venture capitalists converge with that of maximizing social welfare. (shrink)

EDITOR’S ABSTRACTThis article argues that the early Laozi text underwent three stages: The first had section divisions on the basis of the meaning. The second stage was the formative period of the Laozi text influenced by cosmological numerology; the Silk Manuscript version A is its testimony. The third stage finalized the text through the canonization of the Classic by Emperor Jing; it is represented by the Peking University Han Bamboo Slips, Yan Zun, and Liu Xiang versions and became the received (...) edition. From the Han Bamboo Slips to the Liu Xiang version, the Laozi’s two parts and section numbering became increasingly balanced and symmetric. Ding urges scholars to pay attention to all these developments when studying the Laozi text. (shrink)

In this paper we investigate problems about densities ofe-generic,s-generic andp-generic degrees. We, in particular, show that allp-generic degrees are non-branching, which answers an open question by Jockusch who asked: whether alls-generic degrees are non-branching and refutes a conjecture of Ingrassia; the set of degrees containing r.e.p-generic sets is the same as the set of r.e. degrees containing an r.e. non-autoreducible set.