How the formidable diversity of forms emerges from developmental and evolutionary processes is one of the most fascinating questions in biology. The homeodomain‐containing Hox proteins were recognized early on as major actors in diversifying animal body plans. The molecular mechanisms underlying how this transcription factor family controls a large array of context‐ and cell‐specific biological functions is, however, still poorly understood. Clues to functional diversity have emerged from studies exploring how Hox protein activity is controlled through interactions with PBC class (...) proteins, also evolutionary conserved HD‐containing proteins. Recent structural data and molecular dynamic simulations add further mechanistic insights into Hox protein mode of action, suggesting that flexible folding of protein motifs allows for plastic protein interaction. As we discuss in this review, these findings define a novel type of Hox‐PBC interaction, weak and dynamic instead of strong and static, hence providing novel clues to understanding Hox transcriptional specificity and diversity. (shrink)

(in press, under contract with MIT Press, accepted on June 30th, 2006). Attention, Information and Epistemic Perception. In Terzis, G. & Arp, R. (Eds) Information and the Living Systems: Essays in the Philosophy of Biology. The MIT Press. (14,000 words).

It is commonly assumed that moral deliberation requires that the alternatives available in a choice situation are evaluatively comparable. This comparability assumption is threatened by claims of incomparability, which is often established by means of the small improvement argument (SIA). In this paper I argue that SIA does not establish incomparability in a stricter sense. The reason is that it fails to distinguish incomparability from a kind of evaluative indeterminacy which may arise due to the vagueness of the evaluative comparatives (...) ‘better than,’ ‘worse than,’ and ‘equally as good as.’. (shrink)

Many natural languages include plural terms, i.e., terms which denote many individuals at once. Are there also superplural terms, i.e., terms which denote many pluralities of individuals at once? Some philosophers say ‘Yes’, citing a range of sentence-types which apparently can’t be analyzed in a first-order plural logic, but which can be analyzed in a superplural one. We argue that all the data presented in favor of the superplural can, in fact, be analyzed using only first-order resources. The key is (...) to add to ordinary plural logic a new notion of a generalized cover. A generalized cover reflects how interlocutors in a conversation may divide a salient plurality into many subpluralities, which can then be involved in reference and predication. With generalized covers in place, all the apparently troublesome sentences can be easily handled. Our approach can also be extended to account, not only for linguistic data which seem to favor the superplural, but also for other phenomena involving plurals. The result is a unified approach to natural language plurals on which superplurals are analyzed away. (shrink)

This book is the first extensive treatment of Husserl's phenomenology of time-consciousness. Nicolas de Warren uses detailed analysis of texts by Husserl, some only recently published in German, to examine Husserl's treatment of time-consciousness and its significance for his conception of subjectivity. He traces the development of Husserl's thinking on the problem of time from Franz Brentano's descriptive psychology, and situates it in the framework of his transcendental project as a whole. Particular discussions include the significance of time-consciousness for (...) other phenomenological themes: perceptual experience, the imagination, remembrance, self-consciousness, embodiment, and the consciousness of others. The result is an illuminating exploration of how and why Husserl considered the question of time-consciousness to be the most difficult, yet also the most central, of all the challenges facing his unique philosophical enterprise"--Provided by publisher. (shrink)

In order to describe the logic of morality, "contractualist" philosophers have studied how individuals behave when they choose to follow their moral intuitions. These individuals, contractualists note, often act as if they have bargained and thus reached an agreement with others about how to distribute the benefits and burdens of mutual cooperation. Using this observation, such philosophers argue that the purpose of morality is to maximize the benefits of human interaction. The resulting "contract" analogy is both insightful and puzzling. On (...) one hand, it captures the pattern of moral intuitions, thus answering questions about human cooperation: why do humans cooperate? Why should the distribution of benefits be proportionate to each person's contribution? Why should the punishment be proportionate to the crime? Why should the rights be proportionate to the duties? On the other hand, the analogy provides a mere as-if explanation for human cooperation, saying that cooperation is "as if" people have passed a contract-but since they didn't, why should it be so? To evolutionary thinkers, the puzzle of the missing contract is immediately reminiscent of the puzzle of the missing "designer" of life-forms, a puzzle that Darwin's theory of natural selection essentially resolved. Evolutionary and contractualist theory originally intersected at the work of philosophers John Rawls and David Gauthier, who argued that moral judgments are based on a sense of fairness that has been naturally selected. In this book, Nicolas Baumard further explores the theory that morality was originally an adaptation to the biological market of cooperation, an arena in which individuals competed to be selected for cooperative interactions. In this environment, Baumard suggests, the best strategy was to treat others with impartiality and to share the costs and benefits of cooperation in a fair way, so that those who offered less than others were left out of cooperation while those who offered more were exploited by their partners. It is with this evolutionary approach that Baumard ultimately accounts for the specific structure of human morality. (shrink)

El artículo analiza la producción de vacunas en el Instituto Bacteriológico del Departamento Nacional de Higiene de Argentina entre 1913 y 1921. Durante estos años, bajo la dirección del bacteriólogo austríaco Rudolf Kraus, la producción de vacunas fue una apuesta central de las actividades del IB. Para ello, presentamos una reconstrucción de los diferentes aspectos sociales y cognitivos involucrados en estos desarrollos, tales como la selección de los productos, de las técnicas utilizadas, del alcance que tuvieron en su distribución y (...) aplicación efectiva, de las expectativas en torno a su aplicación y de las relaciones y antecedentes a nivel internacional de cada caso, entre otras cuestiones. Proponemos, como eje del análisis, que es posible identificar tres tipos de racionalidades que guiaron el desarrollo de las vacunas, ligadas a las retribuciones o diferentes usos que estas podían redituar en los distintos campos o espacios sociales: una médica-sanitaria, una comercial y una científico-técnica, resultado de las diferentes expectativas y demandas que atravesaron al IB. En términos metodológicos, el trabajo se basa en el análisis de diversas fuentes documentales, tales como trabajos científicos y memorias institucionales del IB y del DNH, trabajos de divulgación profesional o educación universitaria de la época, y bibliografía secundaria de la historia de la ciencia y la medicina. (shrink)

How might a human communication system be bootstrapped in the absence of conventional language? We argue that motivated signs play an important role (i.e., signs that are linked to meaning by structural resemblance or by natural association). An experimental study is then reported in which participants try to communicate a range of pre-specified items to a partner using repeated non-linguistic vocalization, repeated gesture, or repeated non-linguistic vocalization plus gesture (but without using their existing language system). Gesture proved more effective (measured (...) by communication success) and more efficient (measured by the time taken to communicate) than non-linguistic vocalization across a range of item categories (emotion, object, and action). Combining gesture and vocalization did not improve performance beyond gesture alone. We experimentally demonstrate that gesture is a more effective means of bootstrapping a human communication system. We argue that gesture outperforms non-linguistic vocalization because it lends itself more naturally to the production of motivated signs. (shrink)

In a 1993 paper, I argued that empirical treatments of the epistemologyused by scientists in experimental work are too abstract in practice tocounter relativist efforts to explain the outcome of scientificcontroversies by reference to sociological forces. This was because, atthe rarefied level at which the methodology of scientists is treated byphilosophers, multiple mutually inconsistent instantiations of theprinciples described by philosophers are employed by contestingscientists. These multiple construals change within a scientificcommunity over short time frames, and these different versions ofscientific methodology (...) can determine the outcome of a controversy. Iillustrated with a comparatively detailed analysis of the methodologyused by biologists debating the existence of an entity called thebacterial mesosome between the mid-1950s and the mid-1970s. This 1993piece has drawn several critiques in the philosophical literature. Inthis present piece I respond to these critiques and argue that they failto address the core argument of the original paper, and I reflectfurther on the methodologies of philosophers of science pursuingempirical or `naturalistic' epistemology. (shrink)

This paper compares two explanations of the process by which human communication systems evolve: iterated learning and social collaboration. It then reports an experiment testing the social collaboration account. Participants engaged in a graphical communication task either as a member of a community, where they interacted with seven different partners drawn from the same pool, or as a member of an isolated pair, where they interacted with the same partner across the same number of games. Participants’ horizontal, pair‐wise interactions led (...) “bottom up” to the creation of an effective and efficient shared sign system in the community condition. Furthermore, the community‐evolved sign systems were as effective and efficient as the local sign systems developed by isolated pairs. Finally, and as predicted by a social collaboration account, and not by an iterated learning account, interaction was critical to the creation of shared sign systems, with different isolated pairs establishing different local sign systems and different communities establishing different global sign systems. (shrink)

Artificial intelligence and robots may progressively take a more and more prominent place in our daily environment. Interestingly, in the study of how humans perceive these artificial entities, science has mainly taken an anthropocentric perspective (i.e., how distant from humans are these agents). Considering people’s fears and expectations from robots and artificial intelligence, they tend to be simultaneously afraid and allured to them, much as they would be to the conceptualisations related to the divine entities (e.g., gods). In two experiments, (...) we investigated the proximity of representation between artificial entities (i.e., artificial intelligence and robots), divine entities and natural entities (i.e., humans and other animals) at both an explicit (Study 1) and an implicit level (Study 2). In the first study, participants evaluated these entities explicitly on positive and negative attitudes. Hierarchical clustering analysis showed that participants’ representation of artificial intelligence, robots and divine entities were similar, while the representation of humans tended to be associated with that of animals. In the second study, participants carried out a word/non-word decision task including religious semantic-related words and neutral words after the presentation of a masked prime referring to divine entities, artificial entities and natural entities (or a control prime). Results showed that after divine and artificial entity primes, participants were faster to identify religious words as words compared to neutral words arguing for a semantic activation. We conclude that people make sense of the new entities by relying on already familiar entities and in the case of artificial intelligence and robots, people appear to draw parallels to divine entities. (shrink)

A scholarly edition of Nicolas Malebranche's Treatise on Nature and Grace by Patrick Riley. The edition presents an authoritative text, together with an introduction, commentary notes, and scholarly apparatus.

The so-called “Fragment on Machines” of Marx has become in recent decades one of his most revisited texts. This has undoubtedly occurred under the influence of the reading carried out by the school of thought known as Italian autonomism, for whom this text would anticipate the stage of capitalism that opens after the crisis of the 1970s. The “Fragment” would theoretically articulate this stage in terms of a “crisis of value measurement” that would result from the impossibility of framing the (...) new form acquired by labor in “postfordism” into the social norm of working time. The fundamental task of this article is to discuss this interpretative key of the “Fragment” and conceptually articulate its central elements in order to undertake an alternative reading of it, which would also have the potential to critically analyze current capitalism. (shrink)

Las transformaciones acaecidas en el sistema productivo aproximadamente desde principios de la década de 1970 vienen generado una serie de discusiones y posicionamientos teóricos respecto del lugar del trabajo en las sociedades contemporáneas. Habermas y Gorz son dos de los pensadores que en este contexto han sostenido que las sociedades desarrolladas transitan un modelo en el cual inevitablemente el tiempo de trabajo necesario disminuye, tornándose estructurales la desocupación y precarización laborales. Sin embargo, esto será visto como una oportunidad, pues estos (...) autores entienden que el trabajo habría dejado de ser hace tiempo el lugar en el que los individuos podrían realizarse personal y vitalmente, incluso superado el capitalismo. El desafío radicaría entonces en pensar alternativas ante la crisis de la llamada “sociedad del trabajo”. No obstante, los discursos contemporáneos de gestión empresarial parecen colocar un signo de interrogación a dichos análisis al pregonar el involucramiento activo —personal y afectivo— de los sujetos en los procesos productivos. Lo cual estaría dando lugar a la siguiente paradoja: lo que aquellos autores entendían que sólo podía florecer allende los espacios productivos es precisamente lo que la gestión contemporánea del trabajo demanda en primer lugar, y ello en miras de mejorar la productividad e incrementar las ganancias de las empresas. El objetivo de este artículo es exponer con detalle y rigor conceptual esta paradoja, desde el horizonte ético-epistemológico de una teoría crítica que pueda estudiar el presente detectando tanto sus fisuras como sus posibilidades inmanentes de transformación social y política. (shrink)

The paper explores the relation between philosophy and rhetoric from a new perspective by highlighting the dramatic nature of the dialogue and paying attention not only to what is said about philosophy and rhetoric but also to what is shown, especially through Gorgias' intervention throughout the dialogue in order to save a community of dialogue that inquires into the good and the just. This re-conception of the relation between philosophy and rhetoric implies a re-conception of the practice of politics itself, (...) rooted in a philosophy concerned with turning individual souls toward the good and a rhetoric that motivates individuals to be turned in the same direction by the words of others. El artículo explora la relación entre filosofía y retórica desde una nueva perspectiva al enfatizar la naturaleza dramática del diálogo y, por tanto, poniéndole atención no sólo a lo que se dice sobre filosofía y retórica, sino también a lo que se muestra, especialmente por las intervenciones de Gorgias a lo largo del diálogo con el fin de salvar a la comunidad de diálogo que investiga lo bueno y lo justo. Esta reconcepción de la relación entre filosofía y retórica implica una reconcepción de la práctica de la política misma, fundada en una filosofía que busca girar las almas individuales hacia el bien y una retórica que motiva a los individuos a ser girados en esa misma dirección por las palabras de los otros. (shrink)

Interest in the computational aspects of modeling has been steadily growing in philosophy of science. This paper aims to advance the discussion by articulating the way in which modeling and computational errors are related and by explaining the significance of error management strategies for the rational reconstruction of scientific practice. To this end, we first characterize the role and nature of modeling error in relation to a recipe for model construction known as Euler’s recipe. We then describe a general model (...) that allows us to assess the quality of numerical solutions in terms of measures of computational errors that are completely interpretable in terms of modeling error. Finally, we emphasize that this type of error analysis involves forms of perturbation analysis that go beyond the basic model-theoretical and statistical/probabilistic tools typically used to characterize the scientific method; this demands that we revise and complement our reconstructive toolbox in a way that can affect our normative image of science. (shrink)

This article compares the ability to track individuals lacking mental states with the ability to track intentional agents. It explains why reference to individuals raises the problem of explaining how cognitive agents track unique individuals and in what sense reference is based on procedures of perceptual-motor and epistemic tracking. We suggest applying the notion of singular-files from theories in perception and semantics to the problem of tracking intentional agents. In order to elucidate the nature of agent-files, three views of the (...) relation between object- and agent-tracking are distinguished: the Independence, Deflationary and Organism-Dependence Views. The correct view is argued to be the latter, which states that perceptual and epistemic tracking of a unique human organism requires tracking both its spatio-temporal object-properties and its agent-properties. (shrink)

Many of us, even on our happiest days, struggle to quiet the constant buzz of anxiety in the background of our minds. All kinds of worries--worries about losing people and things, worries about how we seem to others--keep us from peace of mind. Distracted or misled by our preoccupations, misconceptions, and, most of all, our obsession with ourselves, we don't see the world clearly--we don't see the world as it really is. In our search for happiness and the good life, (...) this is the main problem. But luckily there is a solution, and on the path to understanding it, we can make use of the rich and varied teachings that have developed over centuries of Buddhist thought. With clarity and compassion, Nicolas Bommarito explores the central elements of centuries of Buddhist philosophy and practice, explaining how they can improve your life and teach you to live without fear. Mining important texts and lessons for practical guidance, he provides a friendly guide to the very practical goals that underpin Buddhist philosophy. After laying out the basic ideas, Bommarito walks readers through a wide range of techniques and practices we can adopt to mend ingrained habits. Rare for its exploration of both the philosophy that motivates Buddhism and its practical applications, this is a compassionate guide to leading a good life that anyone can follow. (shrink)

As Russell's paradox of "the set of all sets that do not contain themselves" indicated long ago, matters go seriously amiss if one operates an ontology of unrestricted totalization. Some sort of restriction must be placed on such items as "the set of all sets that have the feature F' or "the conjunction of all truths that have the feature G." But generally, logicians here introduce such formalized and complex devices as the theory of types or the doctrine of impredictivity. (...) The present paper argues for the informal and elementary idea that the items invoked in a proper identification have themselves already been identified. Even as an explanation is not satisfactory that proceeds in terms of items that themselves require prior explanation, so the same holds with identification. And heed of this elementary idea suffices to sideline those otherwise paradoxical perplexities. (shrink)

This book features 20 essays that explore how Latin medieval philosophers and theologians from Anselm to Buridan conceived of habitus, as well as detailed studies of the use of the concept by Augustine and of the reception of the medieval doctrines of habitus in Suàrez and Descartes. Habitus are defined as stable dispositions to act or think in a certain way. This definition was passed down to the medieval thinkers from Aristotle and, to a lesser extent, Augustine, and played a (...) key role in many of the philosophical and theological developments of the time. Written by leading experts in medieval and modern philosophy, the book offers a historical overview that examines the topic in light of recent advances in medieval cognitive psychology and medieval moral theory. Coverage includes such topics as the metaphysics of the soul, the definition of virtue and vice, and the epistemology of self-knowledge. The book also contains an introduction that is the first attempt at a comprehensive survey of the nature and function of habitus in medieval thought. The material will appeal to a wide audience of historians of philosophy and contemporary philosophers. It is relevant as much to the historian of ancient philosophy who wants to track the historical reception of Aristotelian ideas as it is to historians of modern philosophy who would like to study the progressive disappearance of the term “habitus” in the early modern period and the concepts that were substituted for it. In addition, the volume will also be of interest to contemporary philosophers open to historical perspectives in order to renew current trends in cognitive psychology, virtue epistemology, and virtue ethics. (shrink)

Abstract: Friends of plural logic—like Oliver & Smiley (2001), Rayo (2002), Yi (2005), and McKay (2006)—have argued that a semantics of plurals based on mereological sums would be too weak, and they have adduced several examples in favor of their claim. However, they have not considered various possible counter-arguments. So how convincing are their own arguments? We show that several of them are easily answered, while some others are more problematic. Overall, the case against mereological singularism—the idea that mereological sums (...) can serve as the semantic values of plurals—turns out to be much less strong than what it is usually presented to be. (shrink)

Sometimes physicians lie to third-party payers in order to grant their patients treatment they would otherwise not receive. This strategy, commonly known as gaming the system, is generally condemned for three reasons. First, it may hurt the patient for the sake of whom gaming was intended. Second, it may hurt other patients. Third, it offends contractual and distributive justice. Hence, gaming is considered to be immoral behavior. This article is an attempt to show that, on the contrary, gaming may sometimes (...) be a physician's duty. Under specific circumstances, gaming may be necessary from the viewpoint of the internal morality of medicine. Moreover, the objections against gaming are examples of what we call the idealistic fallacy, that is, the fallacy of passing judgments in a nonideal world according to ideal standards. Hence, the objections are inconclusive. Gaming is sometimes justified, and may even be required in the name of beneficence. (shrink)

This paper explores the role of iconicity in spoken language and other human communication systems. First, we concentrate on graphical and gestural communication and show how semantically motivated iconic signs play an important role in creating such communication systems from scratch. We then consider how iconic signs tend to become simplified and symbolic as the communication system matures and argue that this process is driven by repeated interactive use of the signs. We then consider evidence for iconicity at the level (...) of the system in graphical communication and finally draw comparisons between iconicity in graphical and gestural communication systems and in spoken language. (shrink)

In this article we examine the role of Entscheider (decision-makers) in the German asylum procedure, both legally and ethical. As the responsibility for deciding on asylum applications lies exclusively with them, their significance for the German asylum procedure can hardly be underestimated. However, over the last few decades the situation of Entscheider changed significantly: While the number and complexity of the cases they have to decide on has increased due to the growing immigration, the requirements for their education have been (...) lowered, owed to critical amendments to the relevant law. We analyze how the law currently defines the role of Entscheider, whether the legal framework is constitutional, and what modifications morality requires. Although the law defining their role seems to be constitutional, Entscheider’s education must be improved and they must be entrusted with the hearing of the applicants to meet what morality requires, we conclude. DOI: 10.17879/95189429199. (shrink)

Recent models of the conceptual system hold that concepts are grounded in simulations of actual experiences with instances of those concepts in sensory-motor systems (e.g., Barsalou, 1999, 2003; Solomon & Barsalou, 2001). Studies supportive of such a viewhave shown that verifying a property of a concept in one modality, and then switching to verify a property of a different concept in a different modality generates temporal processing costs similar to the cost of switching modalities in perception. In addition to non-emotional (...) concepts, the present experiment investigated switching costs in verifying properties of positive and negative (emotional) concepts. Properties of emotional concepts were taken from vision, audition, and the affective system. Parallel to switching costs in neutral concepts, the study showed that for positive and negative concepts, verifying properties from different modalities produced processing costs such that reaction times were longer and error rates were higher. Importantly, this effect was observed when switching from the affective system to sensory modalities, and vice-versa. These results support the embodied cognition view of emotion in humans. (shrink)

This commentary suggests that understanding the “Folk Psychology of Souls” requires studying a problem articulating ontology with psychology: How do human beings, both as perceivers and thinkers, track and refer to (1) living and dead intentional agents and (2) supernatural agents? The problem is discussed in the light of the principle of the ontological commitment in agent tracking.

The theoretical literature on vertical relationships usually assumes that beliefs about secret contracts take specific forms. In a recent paper, Eguia et al. (Games Econ Behav 109:465–483,2018) propose a new selection criterion that does not impose any restriction on beliefs. In this article, we extend their criterion by generalizing it to risk-averse retailers, and we show that risk aversion modifies the size of the belief subsets that support each equilibrium. We conduct an experiment which revisits that of Eguia et al. (...) (Games Econ Behav 109:465–483,2018). We design a new treatment effect on equilibrium selection depending on the retailers’ risk sensitivity. Experimental results confirm the treatment effect: the more sensitivity there is towards risk, the more the equilibrium played is consistent with passive beliefs. In addition, extending Eguia et al.’s (Games Econ Behav 109:465–483,2018) criterion to risk-averse retailers improves its predictive power on the equilibria played, especially for a population of retailers with moderate to extreme risk aversion. (shrink)

Este artículo analiza, a luz de una investigación cualitativa, cómo un grupo de personas en situación de calle se orienta a su constitución como actores sociales. Se indaga en aquellos aspectos relacionales que, en condiciones de profunda exclusión social, emergen como articuladores de acción colectiva. Así, se descubre en ellos un potencial transformador de su entorno y de sus propias vidas, en la medida que se reconocen entre sí como legítimos otros y titulares de derechos. Y en última instancia, se (...) plantea la necesidad de aproximarse a sus experiencias de vida reconociendo sociológicamente sus competencias dialógicas y reflexivas, que les permiten autoafirmarse como sujetos. (shrink)

RésuméLe problème du commencement occupe une place centrale clans la pensée de F. Gonseth. La solution qu'il lui apporte, sur laquelle repose toute sa théorie de la connaissance, est paradoxale en ce sens qu'elle dénic à toute connaissance la possibilityé de s'édifier ex nihilo; or historiquement, la connaissance a bien dû coninicncer tine fois. La levée de ce paradoxe fait appel à des concepts prônés par le récent mouvement systémique.SummaryThe problem of the beginning is important in Gonseth's thought. The solution (...) that he gives, and on which his entire epistemology is based, is paradoxical in that it denies that knowledge may be built up ex nihilo; but, historically, knowlege did indeed at some time have to begin. The resolution of this paradox makes use of concepts adopted by the recent systemics movement. (shrink)