Despite the recent discovery that thalidomide causes limb defects by targeting highly angiogenic, immature blood vessels, several challenges still remain and new ones have arisen. These include understanding the drug's species specificity, determining molecular target(s) in the endothelial cell, shedding light on the molecular basis of phocomelia and producing a form of the drug that is clinically effective without having side effects. Now that the trigger of thalidomide‐induced teratogenesis has been uncovered, a framework is proposed, incorporating and uniting previous models (...) of thalidomide action, explaining how thalidomide causes not just limb defects, but also all the other defects it induces. (shrink)

I defend ethical hedonism, the view that pleasure is the sole good thing, by arguing that it offers the only answer to an argument for moral skepticism. The skeptical problem arises from widespread fundamental moral disagreement, which entails the presence of enough moral error to undermine the reliability of most processes generating moral belief. We know that pleasure is good through the reliable process of phenomenal introspection, which reveals what our experiences are like. If knowing of pleasure’s goodness through phenomenal (...) introspection is the only reliable way to form our initial moral beliefs, we should accept ethical hedonism. (shrink)

What is morality? In Practical Expressivism, I argue that morality is a purely natural interpersonal co-ordination device, whereby human beings express their attitudes in order to influence the attitudes and actions of others. -/- The ultimate goal of these expressions is to find acceptable ways of living together. This 'expressivist' model for understanding morality faces well-known challenges concerning 'saving the appearances' of morality, because morality presents itself to us as a practice of objective discovery, not pure expression. -/- This book (...) demonstrates how a properly developed expressivist view can overcome this objection, by showing that even if moral practice is fundamentally expressive, it can still come to possess those features that make it appear objective (features such as talk and thought of moral disagreement, truth and belief, and the applicability of logical notions to moral sentences). The key to this development is to emphasise the unique and intricate practical role that morality plays in our lives. Practical expressivism is also practical in the further sense that it provides repeatable patterns that expressivists can deploy in coming to understand the apparently objective features of morality. (shrink)

We are constantly called upon to evaluate the evidential weight of testimony, and to balance its deliverances against our own independent thinking. ‘Intellectual autonomy’ is the virtue that is supposed to be displayed by those who engage in cognition in this domain well. I argue that this is at best a misleading label for the virtue, because virtuous cognition in this domain consists in thinking with others, and intelligently responding to testimony. I argue that the existing label supports an excessively (...) individualistic conception of good thinking, both within and outside philosophy. I propose replacing ‘intellectual autonomy’ with ‘intellectual interdependence’, which properly emphasises the depth of our reliance on one another, without suggesting we ought ever to be epistemically servile. (shrink)

Why do people endorse conspiracy theories? There is no single explanation: different people have different attitudes to the theories they say they believe. In this paper, I argue that for many, conspiracy theories are serious play. They’re attracted to conspiracy theories because these theories are engaging: it’s fun to entertain them (witness the enormous number of conspiracy narratives in film and TV). Just as the person who watches a conspiratorial film suspends disbelief for its duration, so many conspiracy theorists do (...) not believe the theories they endorse; rather, they suspend disbelief in them. I argue that the serious play hypothesis explains some characteristic features of conspiracy theories, such as their gamification and the kind of relationship they have to evidence. (shrink)

The widespread conviction that we are living in a post-truth era rests on two claims: that a large number of people believe things that are clearly false, and that their believing these things reflects a lack of respect for truth. In reality, however, fewer people believe clearly false things than surveys or social media suggest. In particular, relatively few people believe things that are widely held to be bizarre. Moreover, accepting false beliefs does not reflect a lack of respect for (...) truth. Almost everyone’s beliefs are explained by rationally warranted trust in some sources rather than others. This allows us to explain why people have false beliefs. (shrink)

Discussions of virtue signaling to date have focused exclusively on the signaling of the moral virtues. This article focuses on intellectual virtue signaling: the status-seeking advertising of supposed intellectual virtues. Intellectual virtue signaling takes distinctive forms. It is also far more likely to be harmful than moral virtue signaling, because it distracts attention from genuine expertise and gives contrarian opinions an undue prominence in public debate. The article provides a heuristic by which to identify possible instances of intellectual virtue signaling. (...) When people with no relevant expertise rapidly move to offer their opinions on a wide range of topics as soon as these topics become fashionable or newsworthy, and especially when these opinions are contrarian, we should suspect them of intellectual virtue signaling. (shrink)

This paper replies to the contributors to a symposium on the book Bad Beliefs. It groups the criticisms and concerns of the contributors under the headings “Gaps and Holes”, “Rationality”, “Epistemic Virtue”, “Agency and Control” and “Nudges”. It defends the view that bad belief formation and maintenance is very importantly rational, though it also acknowledges gaps, limitations and unanswered questions.

Most philosophers think that phenomenal consciousness underlies, or at any rate makes a large contribution, to moral considerability. This paper argues that many such accounts invoke question-begging arguments. Moreover, they’re unable to explain apparent differences in moral status across and within different species. In the light of these problems, I argue that we ought to take very seriously a view according to which moral considerability is grounded in functional properties. Phenomenal consciousness may be sufficient for having a moral value, but (...) it may not be necessary, and it may contribute relatively little to our overall considerability. (shrink)

McKenna’s critique (rather than criticisms) of idealized approaches to epistemology is an important contribution to the literature. In this brief discussion, I set out his main concerns about more idealized approaches, within and beyond social epistemology, before turning to some issues I think he neglects. I suggest that it’s important to pay attention to the prestige hierarchy in philosophy, and to how that hierarchy can serve ideological purposes. The greater prestige of more abstract approaches plays a role in determining what (...) issues and what voices we attend to. (shrink)

There's heated debate around whether people who did terrible things in the past, at a time when there was widespread acceptance of such actions, are appropriately blamed by us, on the grounds they weren't really morally ignorant, or their ignorance was itself culpable. I point to puzzles that arise if we blame them. We need to explain how they could act so badly if they weren't fully ignorant. I argue that plausible answers to that question entail that they're not blameworthy, (...) or that we lack standing to blame them. (shrink)

Most contemporary theories of perception, including leading forms of representationalism and naive realism, are monistic: they assume that to consciously perceive is to deploy only one kind of sensory awareness. Here I instead argue for rich pluralism, which says that to consciously perceive is to deploy two very different kinds of sensory awareness in concert: representational awareness of particulars, and non-representational, partly essence-revealing awareness of sensory qualities.

Many philosophers are aware of the paradoxes of set theory (e.g. Russell's paradox). For many people, these were solved by the iterative conception of set which holds that sets are formed in stages by collecting sets available at previous stages. This Element will examine possibilities for articulating this solution. In particular, the author argues that there are different kinds of iterative conception, and it's open which of them (if any) is the best. Along the way, the author hopes to make (...) some of the underlying mathematical and philosophical ideas behind tricky bits of the philosophy of set theory clear for philosophers more widely and make their relationships to some other questions in philosophy perspicuous. (shrink)

This paper argues that qualia share their physical correlates' locations. The first premise comes from the theory of relativity: If something shares a time with a physical event in all reference frames, it shares that physical event’s location. The second premise is that qualia share times with their correlates in all reference frames. Having qualia and correlates share locations makes relations between them easier to explain, improving both physicalist and dualist theories.

This study examines how the Gödel phenomena are to be treated in core logic. We show in formal detail how one can use core logic in the metalanguage to prove Gödel’s incompleteness theorems for arithmetic even when classical logic is used for logical closure in the object language.

Awarding rights to rivers, forests, and other environmental entities (EEs) is a new and increasingly popular approach to environmental protection. The distinctive feature of such rights of nature (RoN) legislation is that direct duties are owed to the EEs. This paper presents a novel rebuttal of the strongest argument against RoN: the no interest argument. The crux of this argument is that because EEs are not sentient, they cannot possess the kinds of interests necessary to ground direct duties. Therefore, they (...) cannot be legitimate rights-bearers. After considering and rejecting standard responses to this argument, the paper challenges its fundamental assumption: that rights-correlative duties must be grounded in the interests of the rights-bearer. The paper then presents the RoN critic with a dilemma. The critic must either accept that EEs are legitimate rights-bearers, or delegitimise many well-established rights-bearers along with EEs. Either way, the no interest argument loses its force. (shrink)

We compare Fregean theorizing about sets with the theorizing of an ontologically non-committal, natural-deduction based, inferentialist. The latter uses free Core logic, and confers meanings on logico-mathematical expressions by means of rules for introducing them in conclusions and eliminating them from major premises. Those expressions (such as the set-abstraction operator) that form singular terms have their rules framed so as to deal with canonical identity statements as their conclusions or major premises. We extend this treatment to pasigraphs as well, in (...) the case of set theory. These are defined expressions (such as ‘subset of’, or ‘power set of’) that are treated as basic in the lingua franca of informal set theory. Employing pasigraphs in accordance with their own natural-deduction rules enables one to ‘atomicize’ rigorous mathematical reasoning. (shrink)

This book focuses on the nature and importance of harm by providing a sustained defense of the counterfactual comparative account, in particular by extending the account to allow for a certain kind of plural or collective harm. According to the counterfactual comparative account, an event harms a person provided that she would have been better off had it not occurred. On the account defended in this book, there are cases in which some events harm a given individual even though none (...) of them by itself harms the individual. This account aims to solve the most serious problem facing the counterfactual comparative account, a problem involving cases of preemption. In such cases, an intuitively harmful event does not make the victim worse off, since if it had not occurred, another event would have had a similar adverse influence on the victim’s well-being. The book also contains discussion of various competing accounts of harm, and it replies to other challenges to the counterfactual comparative account. It argues, moreover, that an action that would harm a person does not thereby have a strong moral reason against it; if there is a strong moral reason against a harmful act, the reason is due primarily to some of the act’s other features. (shrink)

In Thus Spoke Zarathustra, Nietzsche presents passion as constituting human agency. He encountered this Humean view in Schopenhauer, and recognized its explanatory advantages over Platonic and Kantian rationalism. Zarathustra's poetic speeches anticipate and address contemporary objections to the view that passion constitutes agency. "On the Despisers of the Body" explains why understanding the self as constituted by passion provides better explanations of reasoning, value judgment, and the unity of the self than Christine Korsgaard's neo-Kantian view. "On Enjoying and Suffering the (...) Passions" explains why understanding virtues as constituted by passions provides a better explanation of moral phenomenology than John McDowell's rationalism. (shrink)

Systematic killing has long been associated with some of the darkest episodes in human history. Increasingly, however, it is framed as a desirable outcome in war, particularly in the context of military AI and lethal autonomy. Autonomous weapons systems, defenders argue, will surpass humans not only militarily but also morally, enabling a more precise and dispassionate mode of violence, free of the emotion and uncertainty that too often weaken compliance with the rules and standards of war. We contest this framing. (...) Drawing on the history of systematic killing, we argue that lethal autonomous weapons systems reproduce, and in some cases intensify, the moral challenges of the past. Autonomous violence incentivizes a moral devaluation of those targeted and erodes the moral agency of those who kill. Both outcomes imperil essential restraints on the use of military force. (shrink)

Abstractabstract:In his Pragmatism lectures, William James argued that philosophers' temperaments partially determine the theories that they find satisfying, and that their influence explains persistent disagreement within the history of philosophy. Crucially, James was not only making a descriptive claim, but also a normative one: temperaments, he thought, could play a legitimate epistemic role in our philosophical inquiries. This paper aims to evaluate and defend this normative claim.There are three problems for James's view: (1) that allowing temperaments to play a role (...) within inquiry replaces philosophical disagreement with psychological difference; (2) that including temperaments would allow arbitrary elements to influence the outcome of inquiry; and (3) that such a view assumes an implausible metaphysical picture. Through clarifying the nature of temperaments, and what counts as a satisfactory philosophical theory on a pragmatist account, this paper presents an interpretation of James's metaphilosophical claims that can provide satisfactory responses to these problems. (shrink)

The novice/expert problem is the problem of knowing which apparent expert to trust. Following Alvin Goldman’s lead, a number of philosophers have developed criteria that novices can use to distinguish more from less trustworthy experts. While the criteria the philosophers have identified are indeed useful in guiding expert choice, I argue, they can’t do the work that Goldman and his successors want from them: avoid a kind of testimonial scepticism. We can’t deploy them in the way needed to avoid such (...) scepticism, because it would take genuine expertise to do so. I argue that attempts to deploy them in this sort of deep way involve a kind of transgression akin to, and at least as unreliable as, epistemic trespassing. We should give up trying to solve the novice/expert problem and instead promote better epistemic trust. (shrink)

Neil Gascoigne provides the first comprehensive introduction Richard Rorty's work. He demonstrates to the general reader and to the student of philosophy alike how the radical views on truth, objectivity and rationality expressed in Rorty's widely-read essays on contemporary culture and politics derive from his earliest work in the philosophy of mind and language. He avoids the partisanship that characterizes much discussion of Rorty's work whilst providing a critical account of some of the dominant concerns of contemporary thought. Beginning (...) with Rorty's early work on concept-change in the philosophy of mind, the book traces his increasing hostility to the idea that philosophy is cognitively privileged with respect to other disciplines. After the publication of Philosophy and the Mirror of Nature, this led to a new emphasis on preserving the moral and political inheritance of the enlightenment by detaching it from the traditional search for rational foundations. This emerging project led Rorty to champion 'ironic' thinkers like Foucault and Derrida, and to his attempt to update the liberalism of J. S. Mill by offering a non-universalistic account of the individual's need to balance their own private interests against their commitments to others. By returning him to his philosophical roots, Gascoigne shows why Rorty's pragmatism is of continuing relevance to anyone interested in ongoing debates about the nature and limits of philosophy, and the implications these debates have for our understanding of what role the intellectual might play in contemporary life. This book serves as both an excellent introduction to Rorty's work and an innovative critique which contributes to ongoing debates in the field. (shrink)

As pervasive as the use of the Internet has become in the United States, a huge percentage of the world’s population has yet to ever use a telephone. It seems ironic, then, that there is a concerted effort on the part of industrialized nations to first hook up their traditionally disadvantaged citizens to the Internet and second, to hook up citizens of developing nations. This paper addresses the universal access phenomenon by considering the growth of the Internet in terms of (...) Leaver and Taker users—idioms usually associated with a culture’s interactions with its environment. Leaver cultures interact with their environment in a sustainable manner while Taker cultures produce more than they need and impose their ways upon others. The Internet is explored as a community of users, which in its current state is dominated by Takers. However, realizing the need for a more heterogeneous Internet community, this paper explores incentives for Leaver cultures to assimilate online and methods of improving interface designs to be more intuitive to Leaver communities. It is hoped that a tragedy of the commons of Internet resources can be avoided as more Leavers participate in the sustainment of the Internet as a valuable tool for all communities. (shrink)

I provide an examination and comparison of modal theories for underwriting different non-modal theories of sets. I argue that there is a respect in which the `standard' modal theory for set construction---on which sets are formed via the successive individuation of powersets---raises a significant challenge for some recently proposed `countabilist' modal theories (i.e. ones that imply that every set is countable). I examine how the countabilist can respond to this issue via the use of regularity axioms and raise some questions (...) about this approach. I argue that by comparing them with the `standard' uncountabilist theory, a new approach that brings in arbitrariness rather than the strict controls of forcing is desirable. (shrink)

This article explores whether and how research into biological influences on gender identity can and should inform Christian ethical reflection on gender diversity and gender nonconformity. First, the current state of genetic and neuroscientific research on gender identity is surveyed. While the scientific findings are as yet preliminary, tentative, and sometimes contradictory, researchers argue that they already give grounds for thinking that many biological factors have some influence on gender identity through complex interactions with many social and environmental factors. Next, (...) the article offers some general remarks about how natural scientific findings should—and should not—inform Christian theological and ethical reflection. Finally, three specific proposals are developed for how scientific research can and should inform Christian ethical reflection on gender identity. The article offers both a contribution to this Christian ethical reflection and a case study of how the natural sciences may be used in Christian ethics. (shrink)

We are about to see the emergence of religions devoted to the worship of Artificial Intelligence (AI). Such religions pose acute risks, both to their followers and to the public. We should require their creators, and governments, to acknowledge these risks and to manage them as best they can. However, these new religions cannot be stopped altogether, nor should we try to stop them if we could. We must accept that AI worship will become part of our culture, and we (...) must learn to live with it. Indeed, we should do much more than this. We should value it as a new source of meaning in a rapidly-changing world. AI-based religions deserve respect and recognition alongside other, more established ones, and they should be granted the same level of legal protection. (shrink)

Informally rigorous mathematical reasoning is relevant. So too should be the premises to the conclusions of formal proofs that regiment it. The rule Ex Falso Quodlibet induces spectacular irrelevance. We therefore drop it. The resulting systems of Core Logic $ \mathbb{C}$ and Classical Core Logic $ \mathbb{C}^{+}$ can formalize all the informally rigorous reasoning in constructive and classical mathematics respectively. We effect a revised match-up between deducibility in Classical Core Logic and a new notion of relevant logical consequence. It matches (...) better the deducibility relation of Classical Core Logic than does the Tarskian notion of consequence. It is implosive, not explosive. (shrink)

This Article addresses the question of what limits, if any, freedom of speech would place on holding authors liable for the reputational damage they cause with fiction. By “freedom of speech” I am not referring to the First Amendment but rather to one conception of the moral idea underlying it. According to this conception, the limits that freedom of speech places on the scope of authors’ liability for causing false and defamatory beliefs are whatever limits are necessary to adequately protect (...) our interests as potential authors and audiences, and whose costs are acceptable in terms of other interests. To apply this conception, it will be necessary to identify our interests as potential authors of and audiences for fiction about real people, and to assess how these interests would be affected by different limits. Ultimately, I will argue that freedom of speech is consistent with holding authors liable for reputational damage caused by their violations of fiction’s “veracity rules” and for reputational damage caused by mistakes that their target audience would be expected to make. But liability for beliefs that are traceable to mistakes that only an author’s incidental audience would be expected to make is, I will argue, prohibitedby freedom of speech, so long as the costs of that protection remain acceptable. (shrink)

Clinical ethics consultants are inevitably called to participate in and bear witness to emotionally challenging cases. With the move toward the professionalization of ethics consultants, the responsibility to respond to and address difficult ethical dilemmas is likely to fall to a small set of people or a single clinical ethicist. Combined with time constraints, the urgent nature of these cases, and the moral distress of clinicians and staff encountered during consultation, like other healthcare professionals such as physicians and nurses, clinical (...) ethics consultants could risk burnout. If it is true that clinical ethicists are at risk for burnout, an important strategy to avoid burnout is to develop sound self-care practices. This article reviews the goals and skills of ethics consultation and the role-specific reasons that clinical ethicists may be at risk for burnout, and argues that clinical ethicists may need to engage in self-care practices. Strategies to address burnout are reviewed and opportunities for future research are identified. (shrink)

How does our language relate to reality? This is a question that is especially pertinent in set theory, where we seem to talk of large infinite entities. Based on an analogy with the use of models in the natural sciences, we argue for a threefold correspondence between our language, models, and reality. We argue that so conceived, the existence of models can be underwritten by a weak notion of existence, where weak existence is to be understood as existing in virtue (...) of language. (shrink)

Which is worse: Doing evil or being evil? If we are free to define ourselves through our choices, as existentialism posits, then the latter is worse. This paper attempts to resolve the issue of the difference between religious (group) ethics and the ethics of a person of faith that embraces individuals with an existential understanding. In the existential view, the individual (whether the self or the other) is the primary concern, and so the issue of personal relational morality supersedes religious (...) narratives, social morality and popular ethics (White, 2002). If we think and choose, there is the possibility that we may occasionally make a mistake and do evil. However, if we do not think about our choices, and if the conventions we hold happen to be flawed in some way, then we become defined by a continual cycle of mistakes. Existentialism teaches that we become who we are in the process of making choices; therefore the difference between doing evil and being evil can be found in the small but important flow of thinking, relating and choosing. (shrink)

This collection of essays, published to coincide with Tony Honore's sixty-fifth birthday, focuses on the areas where Honore's thought has made the most significant contribution: Roman law and jurisprudence. Included are essays by P.S. Atiyah, Zenon Bankowski, John Bell, Peter Birks, John W. Cairs, Hugh Collins, David Daube, W. M. Gordon, J. W. Harris Nicola Lacey, A. D. E. Lewis, Detlef Liebs, G. D. MacCormack, Neil MacCormick, G. Maher, Pieter Norr, Alan Rodger, and Peter Stein.

Laypersons serve at critical junctures in the legal process. This article provides an overview of research about layperson roles and draws attention to the research methodologies used in studying them. It also discusses the jury system because, in addition to the fact that this institution has attracted the greatest quantity of empirical research on lay participation in legal processes, the studies have also involved the greatest range of methodological approaches, thus allowing exploration of their various strengths and weaknesses. Research on (...) mixed tribunals, lay magistrates, justices of the peace and other forms of lay participation are also discussed in the article. There are literally hundreds of empirical studies bearing on jury competence and behavior. More systematic research surveying the extent of layperson roles in different cultures and countries is needed and studies of how laypersons actually perform in these roles is crucial. (shrink)

A syllabic acrostic (de-ca-te, “tenth”) has recently been discovered by Leah Kronenberg at Eclogue 4.9–11. The aim of the present article is to adduce further evidence for the intentionality of this acrostic. The article begins by pointing to corroborative clues in the text encompassed by the acrostic itself. Attention is then drawn to the overlooked deni‑acrostic in the previous Eclogue (3.55–58). This acrostical deni, for whose intentionality arguments are likewise adduced, evidently serves to corroborate acrostical decate. This deni‑acrostic is itself (...) confirmed shortly afterwards by decem (Ecl. 3.71), which is in turn an imitation of Theocritus (Id. 3.10). This Theocritean text, which contains the word δέκα in ‘line ten’, provides further corroboration of the decate-acrostic, which is likewise centred around ‘line ten’. In particular it is argued that this passage of Theocritus has inspired the noun which decate can be shown to qualify. (shrink)

Neuroethics has two focuses: ethical issues arising from the sciences of the mind, and the ways in which these same sciences can help us to understand normative questions. In this chapter, I pursue a question in the second kind of neuroethics, exploring how the sciences of the mind help us to understand when agents are responsible for their actions. First, I examine the case of the psychopath, and argue that the relevant data suggests that psychopaths do not act with the (...) kind of quality of will that is plausibly taken to underwrite blameworthiness. I then turn to evidence concerning how we attribute quality of will to other agents, and suggest that it predicts a disposition to overattribute a blameworthy quality of will under certain conditions. If these claims are correct, then we are apt to blame some agents, under some conditions, more than they deserve. Attention to the data can therefore enable us to better calibrate our responsibility judgments. (shrink)

This article approaches defective and overabundant paradigm cells as an opportunity and pitfall for usage-based linguistics. Through reference to two production tasks involving native speakers of Czech, we show how definitions of these two categories are problematized when multiple forms per context are entrenched, or when pre-emption seems to occur in the absence of entrenchment: in other words, pre-emption occurs via entrenchment of uncertainty. We explain the results by adopting a broader, usage-based perspective. We examine the relationship between frequency (as (...) proxy for exposure) and reference-work information (as proxy fora prioristructure) to assess their connection with our experimental results. We assign a role to frequency as helping to form perceptions of “suitable” and “unsuitable” forms, but also note places where non-frequency factors predominate. “Structure” as represented by reference-work recommendations appears to have no significant connection to our experimental results; we discuss reasons for this. (shrink)