The structures of spherical RNA plant tiruses, containing 180 copies of one protein subunit, are closely related to those of the animal RNA picornaviruses, which are built of 60 copies of each of three larger capsid proteins. Other spherical RNA and DNA viruses utilize the same structural motif as building units of the viral capsid. It is therefore probable that many of the simple RNA viruses, whether found in animals or plants, have had a common genetic origin. The original gene (...) may have coded for a protein that bound to specific molecules on the cell surface. (shrink)

Michael G. Titelbaum presents a new Bayesian framework for modeling rational degrees of belief—the first of its kind to represent rational requirements on agents who undergo certainty loss.

Book description: The capacity to represent and think about time is one of the most fundamental and least understood aspects of human cognition and consciousness. This book throws new light on central issues in the study of the mind by uniting, for the first time, psychological and philosophical approaches dealing with the connection between temporal representation and memory. Fifteen specially written essays by leading psychologists and philosophers investigate the way in which time is represented in memory, and the role memory (...) plays in our ability to reason about time. They offer insights into current theories of memory processes and of the mechanisms and cognitive abilities underlying temporal judgements, and draw out fundamental issues concerning the phenomenology and epistemology of memory and our understanding of time. The chapters are arranged into four sections, each focused on one area of current research: Keeping Track of Time, and Temporal Representation; Memory, Awareness and the Past; Memory and Experience; Knowledge and the Past: The Epistemology and Metaphysics of Time. A general introduction gives an overview of the topics discussed and makes explicit central themes which unify the different philosophical and psychological approaches. (shrink)

This article defends the Fixed Point Thesis: that it is always a rational mistake to have false beliefs about the requirements of rationality. The Fixed Point Thesis is inspired by logical omniscience requirements in formal epistemology. It argues to the Fixed Point Thesis from the Akratic Principle: that rationality forbids having an attitude while believing that attitude is rationally forbidden. It then draws out surprising consequences of the Fixed Point Thesis, for instance that certain kinds of a priori justification are (...) indefeasible and that misleading all-things-considered evidence about rational requirements is impossible. Finally, the Fixed Point Thesis is applied to defend the Right Reasons position on peer disagreement, according to which an agent who has drawn the correct conclusion from her evidence should retain belief in that conclusion even in the face of disagreeing peers. (shrink)

Three computational models: a narrative reader (BORIS), an editorial reader (OpEd), and a stream of thought generator (DAYDREAMER), are presented and discussed, with specific focus on the emotion-related processing and representational elements of each. These models exhibit comprehension and/or generation of emotional behaviour through the interaction of cognitive processes (memory retrieval, planning, and reasoning) over intentional constructs (goals and beliefs).

The novel coronavirus disease has become a global pandemic, causing substantial anxiety. One potential factor in the spread of anxiety in response to a pandemic threat is emotion contagion, the finding that emotional experiences can be socially spread through conscious and unconscious pathways. Some individuals are more susceptible to social contagion effects and may be more likely to experience anxiety and other mental health symptoms in response to a pandemic threat. Therefore, we studied the relationship between emotion contagion and mental (...) health symptoms during the COVID-19 pandemic. We administered the Emotion Contagion Scale along with a measure of anxiety in response to COVID-19 and secondary outcome measures of depression, anxiety, stress, and obsessive-compulsive disorder symptoms. These measures were completed by a large student sample in the United States. Data were collected in the months of April and May of 2020 when the fear of COVID-19 was widespread. Results revealed that greater susceptibility to emotion contagion was associated with greater concern about the spread of COVID-19, more depression, anxiety, stress, and OCD symptoms. Consumption of media about COVID-19 also predicted anxiety about COVID-19, though results were not moderated by emotion contagion. However, emotion contagion did moderate the relationship between COVID-19-related media consumption and elevated OCD symptoms. Although limited by a cross-sectional design that precludes causal inferences, the present results highlight the need for study of how illness fears may be transmitted socially during a pandemic. (shrink)

Comparisons, and by that I mean the hunt for essential similarities or at least serious family resemblances, between the ethical views of Western and non-Western thinkers have been a staple of comparative philosophy for quite some time now. Some of these comparisons, such as between the views of Aristotle and Confucius, seem especially apt and revealing. However, I’ve often wondered whether Western “ethical theory”—virtue ethics, deontology, or consequentialism—is always the best lens through which to approach non-Western ethical thought. Particularly when (...) the discussion has turned to Buddhism and Buddhist ethics, theories of this sort at best seem to have an uncertain application. This is not to say that .. (shrink)

Begins by explaining then proving a generalized language dependence result similar to Goodman's "grue" problem. I then use this result to cast doubt on the existence of an objective evidential favoring relation (such as "the evidence confirms one hypothesis over another," "the evidence provides more reason to believe one hypothesis over the other," "the evidence justifies one hypothesis over the other," etc.). Once we understand what language dependence tells us about evidential favoring, our options are an implausibly strong conception of (...) the a priori, a hard externalism on which agents are unable to determine what their evidence favors, or a subjectivist view that makes evidential favoring relative to features of the agent. (shrink)

Paulin and Cahill‐Lane explore the origins of event processing and event prediction in animal evolution. They propose that the evolutionary benefit of being able to predict and thus to quickly react to anticipated events may have triggered the evolution of the earliest nervous systems.

A common objection to sense-datum theories of perception is that they cannot give an adequate account of the fact that introspection indicates that our sensory experiences are directed on, or are about, the mind-independent entities in the world around us, that our sense experience is transparent to the world. In this paper I point out that the main force of this claim is to point out an explanatory challenge to sense-datum theories.

The disjunctive theory of perception claims that we should understand statements about how things appear to a perceiver to be equivalent to statements of a disjunction that either one is perceiving such and such or one is suffering an illusion (or hallucination); and that such statements are not to be viewed as introducing a report of a distinctive mental event or state common to these various disjoint situations. When Michael Hinton first introduced the idea, he suggested that the burden (...) of proof or disproof lay with his opponent, that what was needed was to show that our talk of how things look or appear to one.. (shrink)

In this chapter, we explore the role of habit in giving shape to conscious experience and importantly to our pre-reflective awareness of ourselves which includes the sense of mineness that accompanies our conscious experience. For the most part, discussions in philosophy of mind and phenomenology concerning pre-reflective self-awareness are focused on determining the relationship between phenomenal consciousness and selfhood. For this reason perhaps, the existence of pre-reflective self-awareness is usually appealed to as evidence for a form of selfhood that appears (...) within conscious experience as a component of its synchronic unity. In this chapter, however, we will concern ourselves with the pre-reflective sense of ourselves that appears in conscious experience as it pertains to the diachronic unity of the self—that is the sense of a unitary self as existing over the course of multiple episodic experiences. Our aim is to provide a phenomenological account of the relationship between the minimal, pre-reflective sense of self and what is often termed the ‘narrative self.’ We will argue that habits play a role in preserving the significance of our past in our present experience and in unifying our experience as a self for whom the world is present across disparate episodes of experience. (shrink)

This article engages with Julian Culp’s Democratic Education in a Globalized World from the perspective of political philosophy in a global world. The focus is on liberalism. From this angle, Culp’s book entails three important claims. The first is that a right to basic education on the global level exists, i.e. a right to education for everybody independent of one’s nation state. The second claim is that the implementation of this right is not a task for each nation state alone (...) but of world society as a whole. This implies that countries that are able to provide more than basic education to its citizens have a duty to redistribute part of their excess resources to help poor countries secure basic education for their citizens. Culp’s third claim, relevant to the liberal project, is on the kind of education that is supposed to go global. This education should be free-standing, that is, based on political as opposed to perfectionist arguments. This contribution agrees with the first claim, is sceptical regarding the second one, and disagrees with the third one. (shrink)

'Fundamentals of Bayesian Epistemology' provides an accessible introduction to the key concepts and principles of the Bayesian formalism. This volume introduces degrees of belief as a concept in epistemology and the rules for updating degrees of belief derived from Bayesian principles.--.

The problems of perception feature centrally in work within what we now think of as different traditions of philosophy in the early part of the twentieth century, most notably in the sense-datum theories of early analytic philosophy together with the vigorous responses to them over the next forty years, but equally in the discussions of pre-reflective consciousness of the world characteristic of German and French phenomenologists. In the English-speaking world one might mark the beginning of the period with Russell’s The (...) Problems of Philosophy (Russell 1912) and its nemesis in Austin’s Sense and Sensibilia (Austin 1962 – published posthumously, but given originally as lectures at the end of our period in 1947). On the continent, a corresponding route takes us from Husserl’s Logical Investigations (Husserl 1900/1) to Merleau-Ponty’s Phenomenology of Perception.. (shrink)

For the sake of consistency with settled principles from other theological and ethical questions, there is a need for a Christian reexamination of in vitro fertilization (IVF). Both Old and New Testaments demonstrate that human personal life begins at conception or fertilization. Additionally, the Bible teaches that human beings are persons in the image of God from the very beginning of their existence. Thus, it can be concluded that the embryos created via IVF are persons in God’s image. Applying this (...) to the destruction and freezing of embryos, several limitations or restrictions present themselves—embryos should not be purposefully destroyed or wasted, all embryos ought to be implanted, and embryos should not be frozen. Ultimately, however, due to the immense quantity of embryo wastage, it is concluded that Christians should avoid this form of assisted reproductive technology and consider it a pro-life issue. (shrink)

Recent discussion of Vogel-style “bootstrapping” scenarios suggests that they provide counterexamples to a wide variety of epistemological theories. Yet it remains unclear why it’s bad for a theory to permit bootstrapping, or even exactly what counts as a bootstrapping case. Going back to Vogel's original bootstrapping example, I note that an agent who could gain justification through the method Vogel describes would have available a “no-lose investigation”: an investigation that can justify a proposition but has no possibility of undermining it. (...) The main suggestion of this article is that an epistemological theory should not permit no-lose investigations. I identify necessary and sufficient conditions for such investigations, then explore epistemological theories that rule them out. If we want to avoid both skepticism and no-lose investigations, we must eschew either Closure or epistemic externalism. (shrink)

Responding to Cappelen and Dever’s claim that there is no distinctive role for perspectivality in epistemology, I argue that facts about the outcomes of one’s own reasoning processes may have a different evidential significance than facts about the outcomes of others’.

ABSTRACT A recent approach for bioterrorism risk management calls for stricter regulations over biotechnology as a way to control subversion of technology that may be used to create a man‐made pandemic. This approach is largely unworkable given the increasing pervasiveness of molecular techniques and tools throughout society. Emerging technology has provided the tools to design much deadlier pathogens but concomitantly the ability to respond to emerging pandemics to reduce mortality has also improved significantly in recent decades. In its historical context (...) determining just how ‘risky’ biological weapons is an important consideration for decision making and resource allocation. Management should attempt to increase capacity, share resources, provide accurate infectious disease reporting, deliver information transparency and improve communications to help mitigate the magnitude of future pandemics. (shrink)

We evaluate several significant objections to the possibility of group belief. These incredulity objections urge that the very concept of group belief is suspect or incoherent. Although many other...

I argue that given standard deontic logic, wide-scope rational requirements entail narrow-scope rational requirements. In particular, the widely-embraced Enkratic Principle entails that if a particular combination of attitudes is rationally forbidden, it is also rationally forbidden to believe that that combination of attitudes is required.

Scientific knowledge and technological expertise continue to evolve rapidly. Such innovation gives rise to new benefits as well as risks, at an ever-increasing pace. Within this context, regulatory regimes must function in order to address policymakers’ objectives. Innovation, though, can challenge the functioning and effectiveness of regulatory regimes. Questions over fit, effectiveness, and capacity of these regimes to ensure the safe entry of such technologies, and their products, onto the market will be asked in parallel to their development. With this (...) in mind, this article examines the strengths and weaknesses of current regulatory frameworks, including those designed for biotechnology, cosmetics, novel organisms, and foods, in order to inform and help shape Australia’s regulatory landscape around innovation. By focusing on Australia, the article illustrates the need to assess future changes to regulatory frameworks using a careful balancing of key factors. These include, for example, horizon scanning and monitoring, availability of appropriate data, existing health, safety, environmental, ethical, and social risks and impacts, and regulatory capacity. The article argues that rather than using one of these factors in isolation, a careful assessment of where each factor stands can lead regulators to an approach that properly manages the potential risks of emerging technologies. (shrink)

Anti-foundationalism is a central topic in recent legal scholarship. The critical legal studies movement (CLS) has mounted a strong challenge to the traditional belief that legal materials (constitutions, statutes, and precedents) determine legal outcomes and constrain judicial decision making. This scholarship has overlooked, however, the degree to which the debate between traditional legal determinacy and anti-foundational indeterminacy is yet another manifestation of a continuous debate in Western thought – one that has its roots in pre-Socratic rhetoric and philosophy.This paper traces (...) the indeterminacy thesis back to the contest of ideas between Protagoras and Plato. I examine two well-known and elated Protagorean notions: first, that two arguments (logoi) are always set in opposition to one another with regard to every matter and, second, that the rhetorician can always ‘make the weaker argument the stronger.’ I contend that taking these Protagorean notions seriously – perhaps even more seriously than self-avowed anti-foundationalists customarily do – leads paradoxically to a modified endorsement of foundationalism that is nevertheless wholly consistent with the Protagorean project. Calling upon texts by Aristotle, Seneca and René Girard, I focus upon how fictionality in representations of Platonically conceived Truth reveals a binarization in thought that is simultaneously untenable and unavoidable. (shrink)

In his article "Can the East Help the West to Value Nature?" Holmes Rolston, III, wrote that Eastern religious insights would need considerable reformulation in order for us to answer affirmatively the question posed in his title. The present article, while arguing that such an assessment is unduly harsh, goes on to evaluate critically the various Asian ideas of nature, arguing that their ethical consequences are no worse than those of the postmodern concept of nature endorsed by Rolston, Callicott, and (...) others. (shrink)

Disjunctivism about perceptual appearances, as I conceive of it, is a theory which seeks to preserve a naïve realist conception of veridical perception in the light of the challenge from the argument from hallucination. The naïve realist claims that some sensory experiences are relations to mind-independent objects. That is to say, taking experiences to be episodes or events, the naïve realist supposes that some such episodes have as constituents mind-independent objects. In turn, the disjunctivist claims that in a case of (...) veridical perception like this very kind of experience that you now have, the experiential episode you enjoy is of a kind which could not be occurring were you having an hallucination. The common strategy of arguments from hallucination set out to show that certain things are true of hallucinations, and hence must be true of perceptions. For example, it is argued that hallucinations must have non-physical objects of awareness, or that such states are not relations to anything at all, but are at best seeming relations to objects. In insisting that veridical perceptual experience is of a distinct kind from hallucination, the disjunctivist denies that any of these conceptions of hallucination challenges our conception of veridical perceptions as relations to mind-independent objects. More specifically, I assume that the disjunctivist advocates naïve realism because they think that this position best articulates how sensory experience seems to us to be just through reflection. If the disjunctivist is correct in this contention, then anyone who accepts the conclusion of the argument from hallucination must also accept that the nature of sensory experience is other than it seems to us to be. In turn, one may complain that any such error theory is liable to lead to sceptical consequences. A Humean scepticism about the senses launches a challenge about our knowledge of the world through questioning the conception we have of what sense experience is, and how it can provide knowledge of the world. (shrink)

By naturalized epistemology, I mean those views expressed by Nozick and Margolis among others who favor an evolutionary account of human rationality as an adaptive mechanism which is unlikely to provide the means for its own legitimation and therefore unlikely to produce a single set of rules or norms which are certifiably rational. Analyzing the likely relativism that stems from such a view, namely that there could be divergent standards of rationality under different historical or environmental conditions, I conclude that (...) evolutionary epistemologies are unable to account for rationality as an experienced capacity on the part of human beings. After giving a few examples of what seem to me to be cases where we do experience a form of reason that appears antinomian, I challenge a naturalized view of mind to embrace and provide some sort of explanatory account of this kind of mental elasticity that it both seems to make room for and is certainly not unfamiliar to other philosophical perspectives such as that of Zen Buddhism. (shrink)

This study examined the influence of 7 high school esports developmental programs on student self-regulation, growth mindset, positive youth development, perceived general health and physical activity, and sport behaviour. A total of 188 students originally participated, with 58 participants completing both pre- and post-program information. At baseline, no significant differences were found between youth e-athletes and their aged-matched controls. The analysis for the observation period showed a significant interaction effect for the PYD confidence scale, with post-hoc comparisons showing a significant (...) decrease in the control group from pre- to post assessment whereas the esports group remained the same. Time main effects showed a decrease in the self-regulation motivation factor, PYD connection factor and PA for all participants. Overall, this study showed that students enrolled in their respective school esports program did not differ from those who did not in self-regulation, growth mindset, PYD, perceived health and PA, and sport behaviour. It was likely that all participants showed a decrease in motivation, connection, and PA due to COVID19 lockdown during the study period. This study is the first to investigate the longitudinal impact of student involvement in high school esports and showed that esports participation did not have a negative impact on any health or psychological factors. (shrink)

Starting from the premise that akrasia is irrational, I argue that it is always a rational mistake to have false beliefs about the requirements of rationality. Using that conclusion, I defend logical omniscience requirements, the claim that one can never have all-things-considered misleading evidence about what's rational, and the Right Reasons position concerning peer disagreement.

Metaethicists have recently devoted a great deal of attention to questions about when a fact counts as a reason for or against a particular conclusion, and how such reasons interact. Chapter 9 asks a broader question: When a set of facts counts in favor of some conclusion, is that always because at least one of those facts is a reason for that conclusion? Examples are offered in which a set supports a conclusion without any fact in that set’s being a (...) reason for. The chapter then assesses the significance of such examples for philosophical methodology, the ‘reasons-first’ program, and metanormative realism. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Writing Anxiety: Christa Wolf’s KindheitsmusterMichael G. Levine (bio)For Diane C.Christa Wolf’s Kindheitsmuster, published in English as Patterns of Childhood, takes very little for granted—least of all the question of beginnings. The novel literally opens with the words of another: “Das Vergangene ist nicht tot; es ist nicht einmal vergangen,” a slightly altered translation of a line from Faulkner’s Requiem for a Nun: “The past is never dead. It’s not (...) even past.” 1 Lacking a proper opening and haunted by the specter of an unmastered and perhaps unmasterable past—of a “model childhood” spent in the East Prussian town of L. during the Third Reich, the text begins by questioning the very possibility of a clean break and a fresh start. This insistent question, raised in a variety of ways throughout the novel, is posed at the outset as a kind of textual stutter, as a perseverating question rehearsed from the beginning—and in lieu of simply beginning—as a series of false starts, as repeated attempts to start over, as a desperate struggle to restart a narrative paralyzed by the anticipation of difficulties still to come. “You lay aside stacks of tentatively filled pages, insert a fresh sheet in the typewriter, and start once again with Chapter 1. As in so many times during the last eighteen months, when you were forced to learn: the difficulties haven’t even begun [die Schwierigkeiten haben noch gar nicht angefangen].” 2 The temporal structure of this passage, found in the second paragraph of the novel, is worth commenting upon, for here the difficult question of how to begin seems to be folded back on itself, turned inside-out, as it were, and reposed as a question of difficulties that apparently have not yet even started. Indeed, only in a text that stammers from the start and begins by beginning over and over again could it be said both that the difficulties have already started and that they have not yet even begun.Already/not yet: such is the split temporal framework of a difficult encounter, of an encounter with difficulties that will never have been confronted as such. 3 The language of confrontation, of squaring off face-to-face, is particularly inappropriate in this context since, as we will see, the difficulties that force “you,” the writer, to begin again are not simply identifiable or avoidable obstacles in the way of writing but, rather, irreducible and irreducibly conflicted aspects of the writing itself. They are what keeps the writing from ever having a self, from ever being one with or self-consciously coming to itself. 4 [End Page 106]While it is tempting to describe Kindheitsmuster as a novel that is self-conscious in the extreme—difficult writing that writes about the difficulties of writing—one should bear in mind that it is a text that repeatedly calls into question the presumed authority and the capacity for self-knowledge of an instance derisively referred to in a passage inexplicably deleted from the English translation as “His Majesty the Ego [Seine Majestät das Ich]” [83]. In an apparent attempt to suspend the privileges usually accorded to—or, rather, autocratically arrogated to itself by—das Ich, the narrator makes a point of scrupulously avoiding the first-person pronoun when referring to herself in the text. (There is, of course, one important exception to this rule toward the end of the novel to which we will return much later.) As was already evident in the passage cited earlier, “You lay aside stacks of tentatively filled pages, insert a fresh sheet in the typewriter, and start once again with Chapter 1,” the narrator employs the second person rather than the first when speaking in the present—as though she could speak of herself at the moment only by speaking to herself. More significant still in this autobiographical novel that deals at length with the narrator’s memories of growing up in Landsberg on the Warthe (now the Polish town of Gorzmploys the second person rather than the first when speaking in the presenerson when referring to the child she used to be.What is one to make of... (shrink)

The central issue addressed in this CUP monograph is whether and how Christian ethics might be able to make a significant contribution to health care ethics today in the public forum of a Western, pluralistic society. It is the twenty-sixth monograph in the larger project (edited by Robin Gill) New Studies in Christian Ethics that has received considerable international attention. It offers a fresh basis for health care ethics derived from a detailed exegesis of the Synoptic virtues of compassion, care, (...) faith and humility in order to deepen the widely used secular principles of beneficence, non-maleficence, autonomy and justice in health care ethics. In an early review David Atkinson concluded that Gills excellent, clear, and well-written book is a significant contribution. (shrink)

'Fundamentals of Bayesian Epistemology' provides an accessible introduction to the key concepts and principles of the Bayesian formalism. Volume 2 introduces applications of Bayesianism to confirmation and decision theory, then gives a critical survey of arguments for and challenges to Bayesian epistemology.--.