Embryos and microscopes share a long, remarkable history and biologists have always been intrigued to watch how embryos develop under the microscope. Here we discuss the advances in microscopy which have greatly influenced our current understanding of embryogenesis. We highlight the evolution of microscopes and the optical technologies that have been instrumental in studying various developmental processes. These imaging modalities provide mechanistic insights into the dynamic cellular and molecular events which drive lineage commitment and morphogenetic changes in the developing embryo. (...) We begin the journey with a brief history of microscopy to study embryos. First, we review the principles and optics of light, fluorescence, confocal, and electron microscopy which have been key techniques for imaging cellular and molecular events during embryonic development. Next, we discuss recent key imaging modalities such as light‐sheet microscopy, which are suitable for whole embryo imaging. Further, we highlight imaging techniques like multiphoton and super resolution microscopy for beyond light diffraction limit, high resolution imaging. Lastly, we review some of the scattering‐based imaging methods and techniques used for imaging human embryos. (shrink)

Consumers are increasingly facing product evaluation and choice situations that include information about product sustainability, i.e., information about a product’s relative environmental and social impact. In many cases, consumers have to make decisions that involve a trade-off between product sustainability and other valued product attributes. Similarly, product and marketing managers need to make decisions that reflect how consumers will respond to different trade-off scenarios. In the current research, we study consumer responses across two different possible trade-off scenarios: one in which (...) consumers face a trade-off between product sustainability and hedonic value, and another in which they must trade-off between product sustainability and utilitarian value. Our results suggest that, overall, consumers are more likely to trade-off hedonic value for sustainability than to trade-off utilitarian value for sustainability. In Studies 1A and 1B, we presented participants with a product choice task and also measured their anticipatory emotions as they contemplated their options. The results suggest that given a trade-off, consumers are more likely to choose a sustainable product when they have to trade-off hedonic value than when they have to trade-off utilitarian value. Further, these studies provide some insight into the emotions underlying this effect. In Study 2, we use a different consumer response measure, relative purchase likelihood, and investigate the effect of trade-off type across categories that vary in the degree to which hedonic and utilitarian attributes are perceived to be important. Our results suggest that the effect of trade-off type still holds, yet is moderated by product type such that consumers’ greater willingness to trade-off hedonic value for sustainability is attenuated as the relative importance of hedonic attributes increases. In addition to building on our theoretical understanding of decision making given trade-offs with moral attributes, this research is also intended to support managers as they define and choose among various strategic, product development, and marketing promotion options. (shrink)

The development of cultural heritage tourism (CHT) frequently encounters obstacles pertaining to community support, as the attitudes of the local populace typically dictate the outcome of tourism endeavors. The community's influence on these perceptions has been undervalued in traditional approaches, which has resulted in low levels of engagement and support for cultural preservation. This study aims to bridge this gap by investigating how different degrees of community involvement impact local perceptions of the advantages of tourism, the preservation of culture, and (...) general satisfaction with the results. Data was gathered from 300 participants who were actively involved in many heritages sites' tourism planning. The connections between perceptions of the advantages of tourism and community involvement (CI) were evaluatedby utilizing Partial Least Squares Structural Equation Modeling (PLS-SEM). The results demonstrated that the perceptions of economic benefits (PEB), perceptions of cultural preservation (PCP), and community satisfaction (CS) are all positively impacted by greater CI. The aforementioned results underscore the significance of adopting participatory methodologies, implying that cultivating community engagement is vital for the sustainable growth of CHT. (shrink)

The success of an organization depends on its quality management (QM) and organizational culture (OC). While QM seeks to improve the caliber of products and services, OC consider to share beliefs and behaviors that impact working relationships. Together, they deliver excellent performance and a competitive advantage. The goal of the study is to evaluate how various OC factors affect QM methods and their effectiveness. The comprehensive evaluation provided by the study is based on data from 320 experts, validated questionnaires and (...) advanced statistical techniques like correlation analysis, ANOVA and multiple regression. The study shows a significant relationship between certain OC variables and QM outcomes, highlighting the advantages of process adherence, communication process and encouraging leadership style on the effectiveness of QM and customer satisfaction. OC must be in line with QM objectives to improve customer experiences and organizational success. The research highlights the significance of integrating OC elements into QM strategies to foster an environment that drives higher output and improved customer satisfaction. (shrink)

Speech perception has been a very productive and important area in psycholinguistics. In this review easy, I discuss Cutler's new book on native language listening. Cutler argues for a theory of speech perception, where all speech perception is accomplished by competence in native speech. I review this book and attempt to situate its main contributions in the broader context of cognitive science.

Misinformation surrounding the Sustainable Development Goals (SDGs) has contributed to the formation of misbeliefs among the public. The purpose of this paper is to investigate public sentiment and misbeliefs about the SDGs on the YouTube platform.,The authors extracted 8,016 comments from YouTube videos associated with SDGs. The authors used a pre-trained Python library NRC lexicon for sentiment and emotion analysis, and to extract latent topics, the authors used BERTopic for topic modeling.,The authors found eight emotions, with negativity outweighing positivity, in (...) the comment section. In addition, the authors identified the top 20 topics discussing various SDGs and SDG-related misbeliefs.,The authors reported topics related to public misbeliefs about SDGs and associated keywords. These keywords can be used to formulate social media content moderation strategies to screen out content that creates these misbeliefs. The result of hierarchical clustering can be used to devise and optimize response strategies by governments and policymakers to counter public misbeliefs.,This study represents an initial endeavor to gain a deeper understanding of the public’s misbeliefs regarding SDGs. The authors identified novel misbeliefs about SDGs that previous literature has not studied. Furthermore, the authors introduce an algorithm BERTopic for topic modeling that leverages transformer architecture for context-aware topic modeling. (shrink)

Objective Moral distress is a complex phenomenon experienced by healthcare professionals. This study examined the relationships between key dimensions of Organizational Culture in Healthcare (OCHC)—perceived psychological safety, ethical climate, patient safety—and healthcare professionals’ perception of moral distress.Design Cross-sectional surveySetting Pediatric and adult critical care medicine, and adult hospital medicine healthcare professionals in the United States.Participants Physicians (n = 260), nurses (n = 256), and advanced practice providers (n = 110) participated in the study.Main outcome measures Three dimensions of OCHC were (...) measured using validated questionnaires: Olson’s Hospital Ethical Climate Survey, Agency for Healthcare Research and Quality’s Patient Safety Culture Survey, and Edmondson’s Team Psychological Safety Survey. The perception of moral distress was measured using the Moral Distress Amidst a Pandemic Survey. The hypothesized relationships between various dimensions were tested with structural equation modeling (SEM).Results Adequate model fit was achieved in the SEM: a root-mean-square error of approximation =0.072 (90% CI 0.069 to 0.075), standardized root mean square residual = 0.056, and comparative fit index =0.926. Perceived psychological safety (β= −0.357, p <.001) and patient safety culture (β = −0.428, p<.001) were negatively related to moral distress experience. There was no significant association between ethical climate and moral distress (β = 0.106, p = 0.319). Ethical Climate, however, was highly correlated with Patient Safety Culture (factor correlation= 0.82).Conclusions We used structural equation model to test a theoretical model of multi-dimensional organizational culture and healthcare climate (OCHC) and moral distress.Significant associations were found, supporting mitigating strategies to optimize psychological safety and patient safety culture to address moral distress among healthcare professionals. Future initiatives and studies should account for key dimensions of OCHC with multi-pronged targets to preserve the moral well-being of individuals, teams, and organizations. (shrink)

Text document classification and clustering is an important learning task which fits to both data mining and machine learning areas. The learning task throws several challenges when it is required to process high dimensional text documents. Word distribution in text documents plays a very key role in learning process. Research related to high dimensional text document classification and clustering is usually limited to application of traditional distance functions and most of the research contributions in the existing literature did not consider (...) the word distribution in documents. In this research, we propose a novel similarity function for feature pattern clustering and high dimensional text classification. The similarity function proposed is used to carry supervised learning based dimensionality reduction. The important feature of this work is that the word distribution before and after dimensionality reduction is the same. Experiment results prove the proposed approach achieves dimensionality reduction, retains the word distribution and obtained better classification accuracies compared to other measures. (shrink)

Day-to-day lives are affected globally by the epidemic coronavirus 2019. With an increasing number of positive cases, India has now become a highly affected country. Chronic diseases affect individuals with no time identification and impose a huge disease burden on society. In this article, an Efficient Recurrent Neural Network with Ensemble Classifier is built using VGG-16 and Alexnet with weighted model to predict disease and its level. The dataset is partitioned randomly into small subsets by utilizing mean-based splitting method. Various (...) models of classifier create a homogeneous ensemble by utilizing an accuracy-based weighted aging classifier ensemble, which is a weighted model’s modification. Two state of art methods such as Graph Sequence Recurrent Neural Network and Hybrid Rough-Block-Based Neural Network are used for comparison with respect to some parameters such as accuracy, precision, recall, f1-score, and relative absolute error. As a result, it is found that the proposed ERNN-EC method accomplishes accuracy of 95.2%, precision of 91%, recall of 85%, F1-score of 83.4%, and RAE of 41.6%. (shrink)

Tractatus Logico-Philosophicus (TLP) turns hundred years of its publication in the year 2021. The book has received several interpretations during this period of hundred years. However, in the last three decades, the interpretations of TLP have taken a very tenacious position with regard to the debates among scholars concerning whether there is any metaphysical significance in the text. The debates primarily offshoot in the rise of anti-metaphysical or often known as resolute reading that challenges the standard or metaphysical reading. The (...) present paper, however, goes beyond this debate between the resolute and standard reading of TLP. The paper aims at addressing various types of metaphysical reading(s) that has not been perhaps the centre of discussion because the resolute reading takes on only standard reading. Thus, the present paper attempts to show the variety of metaphysical interpretations of the text in some of the recent literatures. (shrink)

This article discusses the importance of human beings ‘material’ (matter) and ‘spiritual’ (spirit) advancement in Rammanohar Lohia’s concept of modernity and modern civilization. Lohia consistently defended materialism (reason) and spirituality as pivotal human values in his writing and speeches. This article engages with his ideas through a detailed reading of his works, focusing particularly on his essays: ‘Materiality and Spirituality’ and ‘Meaning of Modern Civilisation’. According to him, rational thinking emerges from materialism. He believed spiritual instinct keeps a check on (...) the malicious employment of rationality and science; similarly, rationality prevents the perversion of spirituality into superstition and dogmatism. This article articulates two aspects of interpreting modernity: first, it reframes the epistemological understanding of materialism and spirituality, challenging and clarifying prevailing misconceptions; second, it advocates a comprehensive reconstruction of Indian society, which we understand as praxis. His concept of modernity is an amalgamation of theory and praxis. Lohia unequivocally emphasizes that Indian society would reach the height of development by simultaneously engaging in the spiritual and material development of Indian civilization. (shrink)

This book deals with the question of understanding religion and its relationship with politics in the context of developing countries. It reviews specific theories, such as modernisation theory, marxism, liberalism, hermeneutics and critical approach to explain questions related to religion and religious traditions. The book focuses on the recent attempts to theorise religion by Jurgen Habermas. It argues modernisation and orthodox Marxian theory are inadequate in understanding the recent spurt of religious phenomenon in politics. It discusses Hans-Georg Gadamer’s view to (...) show a way forward regarding dialectical hermeneutics in facilitating a dialogue between different traditions and religions. The book is of interest to students, scholars, practitioners of development, and all those who concern themselves with the questions of religion, tradition, modernity and secular well-being in developing countries such as India and beyond. (shrink)

Similarity profiled association mining from time stamped transaction databases is an important topic of research relatively less addressed in the field of temporal data mining. Mining temporal patterns from these time series databases requires choosing and applying similarity measure for similarity computations and subsequently pruning temporal patterns. This research proposes a novel z-space based interest measure named as Krishna Sudarsana for time-stamped transaction databases by extending interest measure Srihass proposed in previous research. Krishna Sudarsana is designed by using the product (...) based fuzzy Gaussian membership function and performs similarity computations in z-space to determine the similarity degree between any two temporal patterns. The interest measure is designed by considering z-values between z = 0 and z = 3.09. Applying the Krishna Sudarsana requires moving the threshold value given by user to a different transformation space which is a defined as a function of standard deviation. In addition to proposing interest measure, new expressions for standard deviation and equivalent z-space threshold are derived for similarity computations. For experimental evaluation, we considered Naïve, Sequential and Spamine algorithms that applies Euclidean distance function and compared performance of these three approaches to Z-Spamine algorithm that uses Krishna Sudarsana by choosing various test cases. Experiment results proved the performance of the proposed approach is better to Sequential approach that uses snapshot database scan strategy and Spamine approach that uses lattice based database scan strategy. (shrink)

Description: Knowledge, Truth and Realism is a collection of essays written by Pranab Kumar Sen over a period of ten years (from 1989 to 1998). The essays deal mainly with issues in Philosophy of Language and Theory of Knowledge from the standpoint of analytical philosophy. They bring forth Sen's realist philosophical position and his attempt to weave together specific questions concerning meaning, reference, truth, knowledge and objectivity in this realistic framework. By responding to and by making use of the (...) ideas of Philosophers like, Gottlob Frege, Ludwig Wittgenstein, W.V. Quine, Donald Davidson, Peter Strawson, H.P. Grice, Michael Dummett, John McDowell, Sen develops his distinctive theory of meaning and understanding along with his theory of knowledge/knowing. In doing so he also addresses the larger issue regarding the nature of philosophical analysis. The essays are a testimony to the painstaking and lifelong engagement of the Philosopher with some of the central and contemporary debates in analytical philosophy. (shrink)

Recent literature on social movements assigns a central role to the imagination. One way for activists to further their aims is through dramatic, confrontational acts of protest. I argue that transcendent imagining is key to understanding what protest does qua act of speech. A common approach to protest sees it as a speech act of condemning some feature of the socio-political world and appealing for change. While this is a helpful general template for what vocal dissent is, it is insufficient (...) to explain what gives protests their political power. Specifically, it overlooks the fact that effective protests usually create a theatrical spectacle of norm breaking. Displays of defiance lift a constraint on how we imagine our socio-political world, and so allow us to begin reshaping it. (shrink)

Health systems are integrating medical-legal partnerships (MLPs) into clinical care and increasingly center “complex care” patients. These patients have intersecting medical and social needs and often face systemic inequities that exacerbate their chronic health conditions. This paper describes a role for MLPs in hospital quality initiatives; examines the ethics of MLPs assisting with guardianship and institutionalization of hospital patients including marginalized groups; and advocates for MLP interventions designed to address intersectional and ethical concerns.

Phonemes have variant pronunciations depending on context. For instance, in American English, the [t] in pat [pæt] and the [d] in pad [pæd] are both realized with a tap [ɾ] when the –ing suffix is attached, [pæɾɪŋ]. We show that despite greater distributional and acoustic support for the [t]-tap alternation, 12-month-olds successfully relate taps to stems with a perceptually-similar final [d], not the dissimilar final-[t]. Thus, distributional learning of phonological alternations is constrained by infants' preference for the alternation of perceptually-similar (...) segments. Further, the ability to relate variant surface forms emerges between 8- and 12-months. Our findings of biased learning provide further empirical support for a role for perceptual similarity in the acquisition of linguistically-relevant categories. We discuss the implications of our findings for phonological theory, language acquisition and models of the mental lexicon. (shrink)

Prof. G.C. Pande in his work ‘ Studies in the Origins of Buddhism ’ speaks of the theory of relation ( paccaya) while discussing the principle of dependent origination ( paṭiccasamuppāda ). Theory of relation ( paccaya) is a law explaining the existence of the dhammas , being related by some relations. It is further extension of the law of dependent origination ( paṭiccasamuppāda ). Things come to existence in our day-to-day life. The law of dependent origination explains that they (...) come into existence; depending upon some other factors. The theory of relation explains that such dependence on the other dhammas is possible due to some relations. In other words, Paṭiccasamuppāda explains the process of existence of conditioned things. The relation ( paccaya ) explains the relation existing between different phases coming into existence. Such relations are also explained in conditioned things only. (shrink)

Chiefly on Indic aesthetics; includes study on symbolism in art and literature, religion and culture in India.

Nirbhaya, Asifa, Manisha Valmiki, and the list of victims, (be it women, children or men) in India goes on. There is myriad of legislations enacted in the past to curb the offences, but the crimes in the society seem to be unstoppable. During the COVID time, in the lockdown too, the crimes continued to take place. There were several instances of domestic violence and rapes heard in news. Many instances of suicides were reported. It is really difficult to understand what (...) place in the country is safe for the existence and peaceful survival of any person? The question that arises is whether a victim who comes before the court is provided with the adequate relief? Has the Judiciary or the Parliament done something with this regard? Does the concept of compensatory jurisprudence exist in India? What more is required to be done to enhance the position of victims and rehabilitate them? The research article shall look into the concept of compensatory jurisprudence with respect to India and other nation states as well. There are prevailing enormous laws which discuss about the punishment to be given to the accused person guilty to have committed crime, but unfortunately, there is no specific law regarding the steps to be taken to rehabilitate a victim who has been the subject matter of any crime. The research paper shall deal with various aspects and try to analyse laws or rules, if any, existing with regard to the protection of victims in India or around the globe. It shall also try to look into the role that the States play in rehabilitating and compensating the sufferers and victims of various crimes. The article shall conclude with suggestions as to how the research gaps related to victim reparation be filled. (shrink)

The reluctant revolutionary -- The patent slave -- The golden Dane -- The quantum atom -- When Einstein met Bohr -- The prince of duality -- Spin doctors -- The quantum magician -- A late erotic outburst -- Uncertainty in Copenhagen -- Solvay 1927 -- Einstein forgets relativity -- Quantum reality -- For whom Bell's theorem tolls -- The quantum demon.

In this essay I argue that moral judgment is a natural kind by developing an empirically grounded theory of the distinctive conceptual content of moral judgments. Psychological research on the moral/conventional distinction suggests that in moral judgments right and wrong, good and bad, praiseworthiness and blameworthiness, etc. are conceptualized as serious, general, authority-independent, and objective. After laying out the theory and the empirical evidence that supports it, I address recent empirical and conceptual objections. Finally, I suggest that the theory uniquely (...) accounts for the possibility of genuine moral agreement and disagreement. (shrink)

Do psychopaths make moral judgments but lack motivation? Or are psychopaths’ judgments are not genuinely moral? Both sides of this debate seem to assume either externalist or internalist criteria for the presence of moral judgment. However, if moral judgment is a natural kind, we can arrive at a theory-neutral criterion for moral judgment. A leading naturalistic criterion suggests that psychopaths have an impaired capacity for moral judgment; the capacity is neither fully present nor fully absent. Psychopaths are therefore not counterexamples (...) to internalism. Nonetheless, internalism is empirically problematic because it is unable to explain psychopaths’ moral deficits. (shrink)