399 a.C.: la città di Atene condanna a morte uno dei suoi figli più autorevoli, Socrate. Cosa è successo davvero nei mesi in cui si è svolta la vicenda giudiziaria? Si ripete spesso che si trattò di un processo politico mascherato, per colpire le simpatie oligarchiche dell'anziano filosofo. Ma forse il vero oggetto del contendere in questa vicenda fu proprio il pensiero di Socrate. Fino a che punto una comunità--ieri come oggi--può tollerare che i principi e i valori su cui (...) si fonda siano messi radicalmente in discussione? E davvero le ragioni della filosofia e quelle della città non sono compatibili? Una lettura originale di uno dei più celebri processi della storia. (shrink)

One of the difficulties nurses experience in clinical practice in relation to ethical issues in connection with young oncology patients is moral distress. In this descriptive correlational study, the Moral Distress Scale-Paediatric Version (MDS-PV) was translated from the original language and tested on a conventional sample of nurses working in paediatric oncology and haematology wards, in six north paediatric hospitals of Italy. 13.7% of the total respondents claimed that they had changed unit or hospital due to moral distress. The items (...) with the highest mean intensity in the sample were almost all connected with medical and nursing competence and have considerably higher values than frequency. The instrument was found to be reliable. The results confirmed the validity of the MDS-PV (Cronbach’s alpha = 0.959). This study represents the first small-scale attempt to validate MDS-PV for use in paediatric oncology-ematology nurses in Italy. (shrink)

RESUMO Este texto delineia, a partir de Foucault, Fassin, Rancière e Butler, a existência de um enquadramento biopolítico de cidadãs e mulheres empobrecidas no contexto da implementação de políticas sociais. A reflexão aqui desenvolvida apresenta resultados parciais de projeto de pesquisa desenvolvido com apoio do CNPq, no qual são analisadas 150 imagens relacionadas ao Programa Bolsa Família, reunidas entre os anos de 2003 a 2015, publicadas nos veículos Folha de S. Paulo, Estado de S. Paulo, O Globo, Veja e IstoÉ. (...) O argumento central é que esse enquadramento envolve a produção de narrativas que traçam distinções entre modos de vida considerados “dignos” e outros não, ressaltando situações de vulnerabilidade da vida e da governamentalidade que formata cenas de aparência, preparando-as para definir cidadãos e grupos exemplares a partir de determinados parâmetros de consideração e apreciação. ABSTRACT From the perspectives of Foucault, Fassin, Rancière and Butler, this paper outlines the existence of a biopolitical framing in press pictures of impoverished women included in the Bolsa Familia social project. The present reflection is based on the partial results of a research project developed with the financial support of CNPq in which we analyze a total of 150 pictures related to the Bolsa Família Program. They were collected from the newspapers Folha de S. Paulo, O Estado de S. Paulo, O Globo, and the magazines Veja and IstoÉ from 2003 to 2015. We argue that the biopolitical framing involves the production of narratives that distinguish ways of life that are “dignified” from those that are not. It also highlights situations of vulnerability and governmentality that shape appearances and prepare them to define citizens and exemplary groups, using certain parameters for consideration and appreciation. (shrink)

The DNA in human cells is continuously undergoing damage as consequences of both endogenous processes and exposure to exogenous agents. The resulting structural changes can be repaired by a number of systems that function to preserve genome integrity. Most pathways are multicomponent, involving incision in the damaged DNA strand and resynthesis using the undamaged strand as a template. In contrast, O6-alkylguanine-DNA alkyltransferase is able to act as a single protein that reverses specific types of alkylation damage simply by removing the (...) offending alkyl group, which becomes covalently attached to the protein and inactivates it. The types of damage that ATase repairs are potentially toxic, mutagenic, recombinogenic and clastogenic. They are generated by certain classes of carcinogenic and chemotherapeutic alkylating agents. There is consequently a great deal of interest in this repair system in relation to both carcinogenesis and cancer chemotherapy. BioEssays 24:255–266, 2002. © 2002 Wiley Periodicals, Inc.; DOI 10.1002/bies.10063. (shrink)

Theory of Mind(ToM) is a neurocognitive system that allows the perceiver to attribute mental states, such as intentions, beliefs, or feelings, to others’ actions. The aim of the present work is to analyse the engagement of the ToM system in communication, in particular, in communicative intention processing. To this aim, we propose anIntention Processing Network(IPN) with its own principles and mechanisms, that is, a brain network differentially engaged according to the complex intertwining of the context, goal, and action involved. According (...) to our IPN model, a set of brain regions of the ToM system (i.e. left and right temporoparietal junction, precuneus, and medial prefrontal cortex) are differentially involved in comprehending different types of intention, such as private or social intentions. We provide independent and convergent evidence on the role of the IPN model in communicative intention processing and we show that the engagement of the IPN does not depend upon the communicative means used, that is, written language, auditory language, or gesture. Evidence deriving from different experimental paradigms, including neuroimaging, lesion, neurodegenerative, and brain stimulation studies are discussed. In our view, this evidence establishes a link between ToM and pragmatics studies and suggests the role of intention processing as a core feature of human communication. (shrink)

The paper is a review of Talal Debs and Michael Redhead's 2007 book, Objectivity, Invariance, and Convention, Harvard, Harvard University Press.

O artigo analisa a atuação de Alberto Antoniazzi na Igreja do Brasil. Demarca seu pensamento e sua contribuição em diversas áreas do conhecimento. Situa, no contexto da cultura contemporânea, os desafios que enfrentou. Mostra que as mudanças pelas quais passa o pensamento religioso não se devem apenas a seu movimento interno, mas são ditadas pela própria história. Com uma fundamentação multidisciplinar, as análises, as pesquisas e os projetos desse pensador descortinaram novos horizontes para a experiência religiosa. Palabras clave: Memória; Catolicismo; (...) Conhecimento; Cultura; História. ABSTRACT This article analyses Alberto Antoniazzi work in the Church of Brazil. It outlines his thought and his contribution in many fields of knowledge, identifying the challenges he faced within the context of contemporary culture. It demonstrates that current changes in religious thought do not result merely from its inner movement, but from history itself. With beasis on a multidisciplinary foundation, that scholar’s analyses, research and projects have disclosed new horizons for the religious experience. Key words: Memory; Catholicism; Knweledge; Culture; History. (shrink)

Der Triestiner Vittorio Benussi (1878-1927), Mitglied der Grazer gegenstandstheoretischen und psychologischen Schule um Alexius Meinong, war einer der bedeutendsten Experimentalpsychologen seiner Zeit. Seine Pionierleistungen auf dem Gebiet der experimentellen Gestaltpsychologie gerieten jedoch bald durch die fortschreitende Durchsetzung der Berliner Schule der Gestalttheorie in Vergessenheit, so daß sein Werk bis heute weitgehend unbekannt geblieben ist. Benussis wissenschaftliche Tätigkeit, die sich durch eine streng experimentelle Vorgangsweise auszeichnet, erweist sich rückblickend als fruchtbarer Anknüpfungspunkt für die zeitgenössische Kognitionswissenschaft. Dies ermöglicht eine Neubewertung seiner wissenschaftlichen (...) Arbeit und jener aktpsychologischen Tradition, der er angehörte. Benussis Untersuchungen nehmen ihren Ausgangspunkt in der Voraussetzung der Intentionalität des Psychischen. Seine Arbeiten thematisieren das Problem des subjektiven Eingriffs in die Konstitution der Erfahrungsgegebenheiten, indem sie die Vorherrschaft des Subjektes über die elementaren Sinnesbedingungen betonen. In Benussis Gesamtwerk läßt sich ein einheitliches Programm erkennen: Ausgehend von der Gegenstands- und Produktionstheorie der Grazer Schule, entwickelt Benussi seinen eigenen theoretischen Standpunkt, der ihn - bewußt - der Phänomenologie Husserls nähebringt. Benussi verlagert schrittweise den Schwerpunkt seiner Forschungen von der gegenstandstheoretischen Perspektive zur Hervorhebung der latenten Subjektivität, die im Konstitutionsprozeß des Gegebenen wirksam ist. Leben und Werk Vittorio Benussis rückblickend zu betrachten, heißt sich mit einem Klassiker der Psychologie zu beschäftigen, dessen Modernität erst in der heutigen Zeit erkannt werden kann. (shrink)

My first and main claim is that physics cannot provide empirical evidence for the objectivity of absolute becoming, for the simple reason that it must presuppose it, at least to the extent that classical spacetime theories presuppose an ontology of events. However, the fact that a theory of absolute becoming must be situated in the a priori realm of metaphysics does not make becoming completely irrelevant for physics, since my second claim will consist in showing that relational becoming, once appropriately (...) defined and understood, properly belongs to the tangled set of issues usually referred to with the label “the arrow of time”. In this respect it is argued that the arrow of becoming is more fundamental both than the causal arrow and of other well-known physical processes that are temporally asymmetric. (shrink)

In this paper I will argue that if physics is to become a coherent metaphysics of nature it needs an “interpretation”. As I understand it, an interpretation of a physical theory amounts to offering a precise formulation of its ontological claims and a clear account of how such claims are related to the world of our experience. Notably, metaphysics enters importantly in both tasks: in, because interpreting our best physical theories requires going beyond a merely instrumentalist view of science and (...) therefore using our best metaphysical theories; in, because a philosophical elaboration of the theories of the world that are implicit in our experience is one of the tasks of analytic metaphysics, and bridging possible explanatory gaps or even conflicts between the physical image and the manifest image of the world is a typical philosophical task that involves science and metaphysics. (shrink)

In this paper I argue that the debate between the so-called “presentists” – according to whom only the present is real – and the “eternalists”, according to whom past present and future are equally real, has no ontological significance. In particular, once we carefully distinguish between a tensed and a tenseless sense of existence, it is difficult to find a single ontological claim on which the two parties could disagree. Since the choice of using a tense or a tenseless language (...) is dictated by purely pragmatic reasons, we should abstain from bringing to bear pseudo-debates generated by the “tensed” or the “tenseless theories” of time on the question of understanding the philosophical implications of contemporary spacetime theories, or notions like becoming, change and persistence in time. (shrink)

The literature on the compatibility between the time of our experience--characterized by passage or becoming--and time as is represented within spacetime theories has been affected by a persistent failure to get a clear grasp of the notion of becoming, both in its relation to an ontology of events tt"spreadtt" in a four-dimensional manifold, and in relation to temporally asymmetric physical processes.In the first part of my paper I try to remedy this situation by offering what I consider a clear and (...) faithful explication of becoming, valid independently of the particular spacetime setting in which we operate. Along the way, I will show why the metaphysical debate between the so-called tt"presentiststt" and tt"eternaliststt" is completely irrelevant to the question of becoming, as the debate itself is generated by a failure to distinguish between a tensed and a tenseless sense of tt"existencett". After a much needed distinction between absolute and relational becoming, I then show in what sense classical spacetime physics presupposes both types of becoming, for the simple reason that spacetime physics presupposes an ontology of events. As a consequence, not only does it turn out that using physics to try to provide empirical evidence for the existence of becoming amounts to putting the cart before the horses, but also that the order imposed by tt"the arrow of becomingtt" is more fundamental than any other physical arrow of time, despite the fact that becoming cannot be used to explain why entropy grows, or retarded electromagnetic radiation prevails versus advanced radiation. (shrink)

The paper argues that the formulation of quantum mechanics proposed by Ghirardi, Rimini and Weber (GRW) is a serious candidate for being a fundamental physical theory and explores its ontological commitments from this perspective. In particular, we propose to conceive of spatial superpositions of non-massless microsystems as dispositions or powers, more precisely propensities, to generate spontaneous localizations. We set out five reasons for this view, namely that (1) it provides for a clear sense in which quantum systems in entangled states (...) possess properties even in the absence of definite values; (2) it vindicates objective, single-case probabilities; (3) it yields a clear transition from quantum to classical properties; (4) it enables to draw a clear distinction between purely mathematical and physical structures, and (5) it grounds the arrow of time in the time-irreversible manifestation of the propensities to localize. (shrink)

The paper defends two claims; Viewed from the perspective of the substantivalism/relationism debate, structural spacetime realism is a form of relationism; However, if we managed to reinforce Rynasiewicz’s point that the general theory of relativity makes the substantivalism/relationism dispute “outdated”, the re-elaboration of Stein ’s 1967 version of structural spacetime realism to be proposed here proves to be a good, antimetaphysical solution to the problem of the ontological status of spacetime.

The time of half-sleep : Merleau-Ponty between Husserl and Proust -- Ad limina philosophiae : Merleau-Ponty and the "introduction" to Hegel's Phenomenology of spirit -- Nature : variations on the theme -- The thinking of the sensible.

In this article the theoretic evolution and the empirical-experimental efforts that have led to the affirmation of the bounded/procedural rationality paradigm are discussed. Moreover, the debate on supporters of the "optimization" approach and supporters of the "bounded/procedural rationality" approach is traced, highlighting the irreconcilability of these two approaches and, in retort, a solid defense against a merely "reductionist" attempt of the innovative context of the Simonian theory. Critically going over the debate on decision dynamics, it becomes clear how, due to (...) the uncertain nature of rational processes, it is impossible to establish the decision-making best way. The imperfect character of individual choice is explained by how the decider identifies a solution that appears satisfying in that moment due to cognitive and temporal limits. (shrink)

In this paper I examine the role of dispositional properties in the most frequently discussed interpretations of non-relativistic quantum mechanics. After offering some motivation for this project, I briefly characterize the distinction between non-dispositional and dispositional properties in the context of quantum mechanics by suggesting a necessary condition for dispositionality – namely contextuality – and, consequently, a sufficient condition for non-dispositionality, namely non-contextuality. Having made sure that the distinction is conceptually sound, I then analyze the plausibility of the widespread, monistic (...) ontological thesis about the reducibility of dispositional properties to categorical properties in the context of the philosophy of quantum mechanics. I conclude that with the exception of Bohmian mechanics, the other “minimally realist” views of quantum mechanics require essential dispositions, i.e., dispositions of a non-reducible kind. Interestingly, seen behind the lenses of dispositionalism, Bohr’s and Bohm’s interpretations of quantum mechanics are much closer than it is usually recognized, a fact that could teach us something about the way the quantum world is. (shrink)

In the literature on the compatibility between the time of our experience and the time of physics, the special theory of relativity has enjoyed central stage. By bringing into the discussion the general theory of relativity, I suggest a new analysis of the misunderstood notion of becoming, developed from hints in Gödel's published and unpublished arguments for the ideality of time. I claim that recent endorsements of such arguments, based on Gödel's own ‘rotating’ solution to Einstein's field equation, fail: once (...) understood in the right way, becoming can be shown to be both mind-independent and compatible with spacetime physics. Being a neededtertium quidbetween views of time traditionally regarded as in conflict, such a new approach to becoming should also help to dissolve a crucial aspect of the century-old debate between the so-called A and B theories of time. (shrink)

An analysis of Derrida’s early work engaging Plato, Hegel, and the life sciences. Germs of Death explores the idea of genesis, or dissemination, in the early work of Jacques Derrida. Looking at Derrida’s published and unpublished work from “Force and Signification” in 1963 to Glas in 1974, Mauro Senatore traces the development of Derrida’s understanding of genesis both linguistically and biologically, and argues that this topic is an overlooked thread that draws together Derrida’s readings of Plato and Hegel. Demonstrating (...) how Derrida’s analysis liberates the understanding of genesis from Platonic and Hegelian presupposition, Senatore also highlights Derrida’s engagement with the biological thought of his day. Senatore also shows that the implications of Derrida’s insights extend into contemporary ethical and political questions relating to postgenomic conceptions of life. “Senatore here demonstrates with stunning insight, clarity, and economy that Derrida’s work of the 1960s and ’70s needs to be understood as a radical critique or deconstruction of both the philosophical concept of life (from Plato to Hegel) and the prevailing biological model of heredity as a ‘genetic program.’ It will be impossible henceforth to read Derrida on questions of the trace, dissemination, life, and so on, without coming to terms with ‘the germs of death.’” — Michael Naas, author of The End of the World and Other Teachable Moments: Jacques Derrida’s Final Seminar “The book represents a major contribution to the field of Derrida studies and phenomenology, particularly its attention to the concept of genesis that formed the basis of Derrida’s earliest study of Husserl and the origin of his concept of writing. The unique contribution is the inclusion of the works from the periods of the mid-1970s, which have been neglected in the mainstream scholarship on Derrida.” — Gregg Lambert, author of Philosophy after Friendship: Deleuze’s Conceptual Personae. (shrink)

In this paper I present and defend Rovelli's relation quantum mechanics from some foreseeable objections, so as to clarify its philosophical implications vis a vis rival interpretations. In particular I will ask whether RQM presupposes a hidden recourse to both a duality of evolutions and of ontology. I then concentrate on the pluralistic, antimonistic metaphysical consequences of the theory, due to the impossibility of assigning a state to the quantum universe. Finally, in the last section I note interesting consequences of (...) RQM with respect to the possibility of defining a local, quantum relativistic becoming.Given the difficulties of having the cosmic form of becoming that would be appropriate for priority monism, RQM seems to present an important advantage with respect to monistic views, at least insofar as far as the possibility of explaining our experience of time is concerned. (shrink)

Resumo: Este artigo apresenta a crítica de Nietzsche à metafísica tradicional, priorizando a análise do conceito de verdade. Partimos da suposição de que é necessário delinear a crítica feita por Nietzsche à tradição metafísica a partir de sua análise sobre a verdade. De acordo com Nietzsche, nossa possibilidade de conhecer as coisas não atinge um “em si”. O sentido do verdadeiro se faz para garantir a paz e abolir a guerra de todos contra todos. De acordo com o filósofo alemão, (...) o critério de verdade não é a correta nomeação da realidade. A instituição do “verdadeiro” é produto de um único propósito, o de garantir a vida em sociedade. Para tanto, procuramos realizar a verificação das considerações críticas de Nietzsche procurando refazer o registro dos conceitos presentes no capítulo primeiro de Além do bem e do mal . Também utilizamos os escritos póstumos produzidos no período da juventude. Nosso intento, portanto, é apontar, em linhas gerais, algumas das críticas que Nietzsche faz as ideias modernas.: This paper presents Nietzsche's critique of traditional metaphysics, prioritizing the analysis of the concept of truth. We start from the assumption that it is necessary to outline the critique of Nietzsche's metaphysical tradition from his analysis of the truth. According to Nietzsche, our ability to know things do not reach a "per se". The true meaning of it is to ensure peace and to abolish war of all against all. According to the German philosopher, the criterion of truth is not the correct naming of reality. The institution of "true" is the product of a single purpose, to ensure life in society. Therefore, we perform the verification of critical considerations Nietzsche's looking to redo the record of the concepts presented in the first chapter of beyond the good and the evil. We also use the posthumous writings produced in the period of youth. Our intent, therefore, is to point out, in general terms, some of the criticism that Nietzsche modern ideas. Keywords : Metaphysics. Truth. Modern ideas. (shrink)

Mechanisms are a way of explaining how biological phenomena work rather than why single elements of biological systems are there. However, mechanisms are usually described as physiological entities, and little or no attention is paid to malfunction as an independent theoretical concept. On the other hand, malfunction is the main focus of interest of applied sciences such as medicine. In this paper I argue that malfunctions are parts of pathological mechanisms, which should be considered separate theoretical entities, conceptually having a (...) priority over physiological sequences. While pathological mechanisms can be described in terms of a Cummins-like mechanistic explanation, they show some unnoticed peculiarities when compared to physiological ones. Some features of pathological mechanisms are considered, such as outcome variability, ambivalence and dependence on a range. (shrink)

In the preface of the Philosophical Investigations, Wittgenstein says that his “most fruitful ideas” are due to the stimulus of Sraffa's criticism, but Sraffa is not mentioned anywhere else in the book. It remains a puzzle in the literature how and why Sraffa influenced Wittgenstein. This paper presents a solution to this puzzle. Sraffa's criticism led Wittgenstein away from the calculus conception of language of the Big Typescript (arguably, an adaptation of the calculus of the Tractatus), and towards the “anthropological (...) view,” which structures both the opening sections of the Philosophical Investigations and Wittgenstein's later philosophy of mathematics. (shrink)