Background: Clinical genomic implementation studies pose challenges for informed consent. Consent forms often include complex language and concepts, which can be a barrier to diverse enrollment, and these studies often blur traditional research-clinical boundaries. There is a move toward self-directed, web-based research enrollment, but more evidence is needed about how these enrollment approaches work in practice. In this study, we developed and evaluated a literacy-focused, web-based consent approach to support enrollment of diverse participants in an ongoing clinical genomic implementation study. (...) Methods: As part of the Cancer Health Assessments Reaching Many (CHARM) study, we developed a web-based consent approach that featured plain language, multimedia, and separate descriptions of clinical care and research activities. CHARM offered clinical exome sequencing to individuals at high risk of hereditary cancer. We interviewed CHARM participants about their reactions to the consent approach. We audio recorded, transcribed, and coded interviews using a deductively and inductively derived codebook. We reviewed coded excerpts as a team to identify overarching themes. Results: We conducted 32 interviews, including 12 (38%) in Spanish. Most (69%) enrolled without assistance from study staff, usually on a mobile phone. Those who completed enrollment in one day spent an average of 12 minutes on the consent portion. Interviewees found the information simple to read but comprehensive, were neutral to positive about the multimedia support, and identified increased access to testing in the study as the key difference from clinical care. Conclusions: This study showed that interviewees found our literacy-focused, web-based consent approach acceptable; did not distinguish the consent materials from other online study processes; and valued getting access to testing in the study. Overall, conducting empirical bioethics research in an ongoing clinical trial was useful to demonstrate the acceptability of our novel consent approach but posed practical challenges. (shrink)

'The men of culture are the true apostles of equality.' Matthew Arnold's famous series of essays, which were first published in book form under the title Culture and Anarchy in 1869, debate important questions about the nature of culture and society that are as relevant now as they have ever been. Arnold seeks to find out 'what culture really is, what good it can do, what is our own special need of it' in an age of rapid social (...) change and increasing mechanization. He contrasts culture, 'the study of perfection', with anarchy, the mood of unrest and uncertainty that pervaded mid-Victorian England. How can individuals be educated, not indoctrinated, and what is the role of the state in disseminating 'sweetness and light'? This edition reproduces the original book version and enables readers to appreciate its immediate historical context as well as the reasons for its continued importance today, in the face of the challenges of multi-culturalism and post-modernism. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more. (shrink)

Wijsgerig-ethische verhandeling over de deugd als liefde tot de rede.

Monograph on the historical evolution of women's rights from 1902 to 1978 - describes various campaigns for achieving civil rights for women, rights for political participation, equal opportunities for the woman worker, etc., and considers the contributions made to the emancipation of women by the international alliance of women (interest group), the League of Nations, the UN (role of UN) and other international organizations, the international women's year, etc. ILO mentioned. Bibliography pp. 312 to 314, chronology of major events and (...) photographs. (shrink)

First published in 1959, this book is concerned with the methodology of art history, and so with questions about historical thinking; it enquires what scientific history of art can accomplish, what are its mean and limitations? It contains philosophical reflections on history and begins with chapters on the scope and limitations of a sociology of art, and the concept of ideology in the history of art. The chapter on the concept of "art history without names" occupies the central position in (...) the book — thoroughly discussing the basic philosophical outlook for the whole work. There are also further chapters on psychoanalysis, folk art and popular art. The chapter on the role of convention in the history of art points the way for further study. (shrink)

We shall try to defend two non-standard views that run counter to two well-entrenched familiar views. The standard views are the universal and existential quantifiers of first-order logic are not modal operators, and the quantifiers are extensional. If that is correct then the counterclaims create genuine problems for some traditional philosophical doctrines.

Tackling the question whether beauty is a property as if the problem of universals could safely be ignored leads to confusions exemplified in Scruton 2009, McMahon 2007, Zangwill 2001 and Scarry 1999, among recent writers. I frame the question in the proper context with a measure of precision, clear away misunderstandings, present a logically valid argument for an affirmative answer, list three relevant and four irrelevant ways of countering the argument, and show that well-known views of Hume and Kant yield (...) relevant objections only if construed in Russellian terms, but still fail. Finally, I sketch a realization account of beauty along Platonist lines, similar to Hogarth’s. (shrink)

Der Dialog ist als Mittel und direkter Ausdruck zwischenmenschlicher Kommunikation in unserer Gesellschaft wichtiger denn je. Zugleich ist er aber zunehmend von Gewalt, von medialen Auswüchsen und von der Schnelllebigkeit unserer Zeit bedroht. Angesichts dieser Entwicklung ist Martin Bubers „dialogisches Prinzip“ hochaktuell. Sein Verständnis des Dialogs unterscheidet sich fundamental vom heutigen medialen Diskurs. In seinem Hauptwerk Ich und Du beschreibt Buber die Grundbedingungen für einen guten Dialog. Ein solcher kann nur gelingen, wenn zwei Menschen bereit sind, sich voll und ganz (...) aufeinander einzulassen und dem anderen ohne Vorbehalte oder Vorurteile zu begegnen. Ausgehend von einer Werk- und einer Werkgeschichtsanalyse von Ich und Du reflektiert Gertud Arnold das Potenzial des Buberschen Dialogkonzepts und dessen praktischer Anwendung im Hier und Heute. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

De tweespalt tussen wetenschap en emotionele waarneming werkt ontluisterend. Donder en Bliksem, de regenboog en andere als wonderbaarlijk ervaren natuurverschijnselen worden herleid tot fysieke fenomenen. Hoewel dit ook bevrijdend kan werken, blijft het verschil tussen realiteit en ons perceprievermogen een grote tweespalt genereren.

A special section of papers on the evolution, current status, and future development of self psychology highlights _The Evolution of Self Psychology_, volume 7 of the Progress in Self Psychology series. A critical review of recent books by Basch, Goldberg, and Stolorow et al. is part of this endeavor. Theoretical contributions to Volume 7 examine self psychology in relation to object relations theory and reconsider the relationship of psychotherapy to psychoanalysis. Clinical contributions deal with an intersubjective perspective on countertransference, the (...) trauma of incest, and envy in the transference. (shrink)

_The Widening Scope of Self Psychology_ is a watershed in the self-psychological literature, being a contemporary reprise on several major clinical themes through which self psychology, from its inception, has articulated its challenge to traditional psychoanalytic thinking. The volume opens with original papers on interpretation by eminent theorists in the self-psychological tradition, followed by a series of case studies and clinically grounded commentaries bearing on issues of sex and gender as they enter into analysis. Two thoughtful reexaminations of the meaning (...) and treatment challenges of chronic rage are followed by clinical papers that focus, respectively, on mourning, alter ego transferences, resistance to change, and pathological identification. Applied analytic contributions and a review of Goldberg's _The_ _Prisonhouse of Psychoanalysis_ round out a collection that testifies not only to the widening scope of self psychology, but to its deepening insights as well. (shrink)