Automatic control of physiological variables is one of the most active areas in biomedical engineering. This paper is centered in the prediction of the analgesic variables evolution in patients undergoing surgery. The proposal is based on the use of hybrid intelligent modelling methods. The study considers the Analgesia Nociception Index to assess the pain in the patient and remifentanil as intravenous analgesic. The model proposed is able to make a one-step-ahead prediction of the remifentanil dose corresponding to the current state (...) of the patient. The input information is the previous remifentanil dose, the ANI variable and the electromyogram signal. Modelling techniques used are Artificial Neural Networks and Support Vector machines for Regression combined with clustering methods. Both training and validation were done with a real dataset from different patients. Results obtained show the potential of this methodology to calculate the drug dose corresponding to a given analgesic state of the patient. (shrink)

La discussione generale sulla filosofia della scienza contemporanea è complicata dal numero e dall’eterogeneità delle scienze, mentre lo studio di temi specifici porta inevitabilmente a dissertazioni specialistiche che mancano nel dare ragione della trama di senso sottostante. Questo Piccolo trattato di epistemologia intende occupare uno spazio vuoto, proponendo alcuni temi chiave per la comprensione dei meccanismi alla base della conoscenza scientifica: i rapporti tra filosofia e scienze, siano esse naturali o umane; la complessa relazione tra fatti e valori; la distinzione (...) tra scoperta e giustificazione; la necessità di un discorso etico sulla ricerca, che chiami in causa categorie come fiducia, empatia, altruismo ed egoismo. Con un approccio chiaro e rigoroso, il volume intende rivolgersi a quell’ampia fascia di pubblico interessata alle tematiche centrali dell’epistemologia, della filosofia e delle scienze. (shrink)

In this paper I argue that, in Leibniz’s mature metaphysics, primary matter is not a positive constituent which must be added to the form in order to have a substance. Primary matter is merely a way to express the negation of some further perfection. It does not have a positive ontological status and merely indicates the limitation or imperfection of a substance. To be sure, Leibniz is less than explicit on this point, and in many texts he writes as if (...) primary matter were a positive constituent of a substance. It seems to me, however, that the view most in keeping with the thrust of his mature philosophical system is that captured by a striking remark of 1695: “Materia rerum est nihilum: id est limitatio [The matter of things is nothing: that is, limitation].” This becomes especially apparent in texts showing that Leibniz’s conception of primary matter corresponds to his conception of creaturely limitation. I start by discussing the notion of primary matter in the scholastic tradition. I then show that although Leibniz places the scholastic terminology of primary matter at a crucial juncture of his metaphysics, he thinks of primary matter in a way which significantly deviates from earlier scholastic views. I conclude that despite his adoption of distinctive terminology of Aristotelian scholasticism, instead of holding a broadly Aristotelian concept of primary matter as the ultimate subject of inherence, Leibniz thinks of primary matter according to a Neoplatonic blue-print in which matter is non-being, privation, mere absence of perfection. (shrink)

Razón, poesía, historia.--La cuestión del estoicismo español.--El querer.

The passage of time seems to be a fundamental aspect of experience. However, most descriptions of the passage of time itself are incompatible with the four-dimensional block universe model of space and time, in which time is extended like space, and all states of affairs exist equally and eternally in this varied tapestry of space and time. The tension between temporal passage and the block universe seems to leave one with the option of either abandoning the block universe in favor (...) of a metaphysics that can accommodate our experience, or holding that this experience of passage is illusory. I argue for a third option: that we have certain dynamic experiences, which lend themselves to the view that time passes, those dynamic experiences can be accounted for within the block universe model without any additional mechanism, and those dynamic experiences are not illusory, but veridical. (shrink)

Previous research indicates positive effects of a person’s attractiveness on evaluations of opposite-sex persons, but less positive or even negative effects of attractiveness on same-sex evaluations. These biases are consistent with social motives linked to mate search and intrasexual rivalry. In line with the hypothesis that such motives should not become operative until after puberty, 6- to 12-year-old participants (i.e., children) displayed no evidence for biased social evaluations based on other people’s attractiveness. In contrast, 13- to 19-year-old participants (i.e., adolescents) (...) displayed positive and negative attractiveness biases toward opposite- and same-sex targets, respectively. Moreover, these biases increased with the age—and thus the reproductive relevance—of the targets being evaluated. Findings corroborate the relevance of mating-related motives for social judgment and illustrate how such biases can grow during human development. At a broader conceptual level, this research demonstrates the utility of investigating proximate social judgment processes through the lens of adaptationist thinking. (shrink)

In recent years there has been renewed interest in the participation of lay people in regulatory procedures. The debate peaked in the 1980s with the anti-nuclear movements and again more recently as a reaction to the food scandals of the mid-1990s. In the wake of the bovine spongiform encephalopathy (BSE) crisis there has been a proliferation of European Community rules on the production, processing and retailing of food products, along with the multiplication of scientific committees in order to cope with (...) increased ... (shrink)

IN THE LAST PART of the Theory of Moral Sentiments, Adam Smith puts his theory in a class with those of his contemporaries Francis Hutcheson and David Hume, namely, the systems that make sentiments the principle of approbation. Despite recognizing important differences with both of them, he thinks that since he has placed the origin of moral sentiments in sympathy, and in particular the fact that we are able to enter into the motives of the agent and get pleasure from (...) finding them appropriate to their cause, sentiments are the foundation of his theory of morals. Many of Smith’s commentators, in fact almost all of the most important studies over the last few years, reaffirm the author’s self-description. However, my aim in this paper is to challenge this view by showing that Smith’s system can also be plausibly seen as a theory of practical reasoning, and in some important aspects very similar to Aristotelian ethics. Surprisingly few scholars have seen this parallel. Laurence Berns, Samuel Fleischacker, Charles Griswold, and Gloria Vivenza are the latest exceptions, identifying several points of coincidence between Adam Smith and Aristotle’s ethics. None of them, however, has tied all these similarities under a unified interpretation, such as the one I propose here: The basic analogy between these theories, and the source of those particular coincidences, is the operation of practical reason. Moreover, and besides the common elements with Aristotle’s ethics, Smith’s reconstruction of practical reason simultaneously announces some of the main features of modern accounts of ethics, such as impartiality and universality as preconditions of moral judgment. The integration of these ancient and modern elements in a single coherent theory allows Smith’s TMS to overcome the insufficiencies and paradoxes of both these traditions, and it constitutes one of the most interesting and challenging proposals of modern ethics. (shrink)

RESUMEN El texto explora, en mujeres mayores de 80 años, la experiencia vivida durante el pe ríodo conocido como La Violencia en Colombia. Se examina el "trauma" que, según la autora, se manifiesta como "rayones", lo que hace difícil traducirlo o interpretarlo, porque solo se percibe a través de la escucha. Se estudia lo que M. Heidegger exploró como "ser-ahí" y "ser-en-el-mundo", esto es, el estar lanzados al mundo en un de terminado contexto donde construimos nuestra subjetividad y aprendemos a (...) vivir, para entenderlo mediante estas experiencias femeninas singulares. ABSTRACT The text explores the experience lived during the period known as The Violence in Colombia by women now over 80. It examines the "trauma" that, according to the author, manifests itself in the form of "scratches", thus making it difficult to translate and interpret given that it is only perceptible through listening. The article discusses M. Heidegger's notions of Dasein and being-in-the-world, that is, our thrownness into the world in a specific context in which we construct our subjectivity and learn how to live, in order to understand them through these singular feminine experiences. (shrink)

'Ethics' was not developed as a separate branch of philosophy in Buddhist traditions until the modern period, though Buddhist philosophers have always been concerned with the moral significance of thoughts, emotions, intentions, actions, virtues, and precepts. Their most penetrating forms of moral reflection have been developed within disciplines of practice aimed at achieving freedom and peace. This Element first offers a brief overview of Buddhist thought and modern scholarly approaches to its diverse forms of moral reflection. It then explores two (...) of the most prominent philosophers from the main strands of the Indian Buddhist tradition – Buddhaghosa and Śāntideva – in a comparative fashion. (shrink)

After a brief introduction about the problem of leopardian sources, I wish to introduce here a description of the diffusion of Addison’s theories about the Imagination in Italy at the time of Leopardi, trying to highlight their influence on his thinking and his philosophy. The third chapter is dedicated to the analysis of an important excerpt of the Zibaldone where Leopardi quotes Addison and his Catone to introduce an interesting reflection about the pleasure of beauty and the role of imagination, (...) almost as a way to face Addison issues.This excerpt represents an occasion to compare the theories of Addison and Leopardi about Aesthetics and also the similarities and the differences between them. The last part of the paper is dedicated to the results of the analysis and the conclusions. (shrink)

o presente artigo busca identificar na Critica da faculdade de julgar os pressupostos de que se serviram os artistas plasticos nao figurativos para suas concepções artisticas, atraves do rnetodo de uma analise de conteudo das duas introduções escritas por Kant para sua terceira critica.

Made up from parents and children from a previous union or marriage, often completed by children of the new couple, the recomposed or reconstituted family is problematic under the aspect of family-specific functions, relationships and roles. Being exposed to numerous sources of conflict, it is marked by many functional difficulties, which can lead to rupture and failure. For this unit in diversity to stand the test of time, it is necessary for all the members to engage in an active and (...) flexible involvement. (shrink)

En los últimos años se realizaron numerosos trabajos sobre el tema de la transferencia científico-tecnológica de la Universidad en función de los cambios de orientación en las políticas de Educación Superior implementadas en América Latina en la última década. La mayoría de los estudios sobre el tema parten de la consideración del fenómeno de la vinculación como la actuación de los tres sectores involucrados: sector universitario público, sector estatal y sector de la producción de bienes y servicios, y son escasos (...) los trabajos que abordan la perspectiva de análisis que explora la temática de la vinculación entre estos sectores como la expresión de los actores que se desenvuelven en el ámbito de esta institución. Siguiendo esta perspectiva, este estudio tiene como propósito el análisis de las percepciones y valoraciones generadas por los actores universitarios a partir de las actividades de vinculación Universidad-Estado-Sector productivo. En este trabajo presentamos algunas notas metodológicas sobre esta perspectiva de análisis. (shrink)

Alongside the renowned male pioneers of medical cytogenetics, many women participated in investigations at the laboratory bench and the bedside, both in Europe and the Americas. These women were committed to this new biological and clinical practice—cytogenetics, the origins of contemporary genetic diagnosis—and contributed to the creation of new biological concepts and settings centered on the study of chromosome imaging. This paper will review the contributions made by a group of woman scientists from a wide geographical distribution, situating their names (...) and research agendas within the history of a field dating back to early plant and insect cytogenetics. Rather than an exhaustive compendium of women geneticists, this essay presents a kind of historical reconstruction that can be achieved by placing women at center stage in their geographies and networks of circulating cytogenetic knowledge and practices thereby relating a history of genetic images though the work carried out by women, retrieving their agency and constructing an inclusive history of an influential contemporary biomedical practice as it gained increasing influence in the laboratory and the clinic. (shrink)

Maria Bittner (M2: August 3, 2009) 1. TOWARD SYN-SEM TYPOLOGY • E. Jelinek 1984: W(arlpiri)-TYPE (EJ traits (62.a-f) ~ MB traits BA, TO, L, …).

Since the 1970s, many Anglo-American studies have investigated the theme of corporate social responsibility (CSR) and its costs and benefits. Most studies have tried to test, largely in samples of multiple industries, the relationship between corporate social performance (CSP) and corporate financial performance (CFP). These analyses, however, have produced conflicting results and any attempt to give a generalized and coherent conclusion has proved inadequate. This article examines the ways CSP can be proxied and investigates the possible relationship between CSP (measured (...) by ethical rating) and CFP (measured by market and accounting ratios) in the banking sector using correlation methodology. It emerges that there is no statistically significant link between CSP and CFP. (shrink)

In current debates about coming to terms with individual and collective wrongdoing, the concept of forgiveness has played an important but controversial role. For a long time, the idea was widespread that a forgiving attitude — overcoming feelings of resentment and the desire for revenge — was always virtuous. Recently, however, this idea has been questioned. The contributors to this volume do not take sides for or against forgiveness but rather examine its meaning and function against the backdrop of a (...) more complex understanding of moral repair in a variety of social, circumstantial, and cultural contexts. The book aims to gain a differentiated understanding of the European traditions regarding forgiveness, revenge, and moral repair that have shaped our moral intuitions today whilst also examining examples from other cultural contexts (Asia and Africa, in particular) to explore how different cultural traditions deal with the need for moral repair after wrongdoing. -/- . (shrink)