Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week multi-domain, single-blind, proof-of-concept randomized controlled trial examining the cognitive effect and underlying mechanisms of an aerobic exercise, computerized cognitive training and a combined groups compared to a waitlist control group. Adherence was > 80% for 82/109 participants recruited. In this study we report intervention-related changes in plasma biomarkers and structural-MRI and how they (...) related to changes in physical activity and individual variables and their potential role as mediators in the cognitive changes. Our results show that although there were no significant changes in molecular biomarker concentrations in any intervention group, changes in ICAM-1 and SDF1-α were negatively associated with changes in physical activity outcomes in AE and COMB groups. Brain volume changes were found in the CCT showing a significant increase in precuneus volume. Sex moderated the brain volume change in the AE and COMB groups, suggesting that men may benefit more than women. Changes in molecular biomarkers and brain volumes did not significantly mediate the cognitive-related benefits found previously for any group. This study shows crucial initial molecular and brain volume changes related to lifestyle interventions at early stages and highlights the value of examining activity parameters, individual difference characteristics and using a multi-level analysis approach to address these questions. (shrink)

Resumen: Este artículo se propone analizar las razones por las que las prostitutas, a causa de su opción sexual, han sido criminalizadas por imposición de distintos órdenes normativos, fuertemente coercitivos, que censuran gravemente su desviación. Ellos –y sus potentes discursos-se muestran capaces de explicar ese continuum ininterrumpido e inacabable de estigma, persecución, inferiorización, aislamiento social o encarcelamiento que acompaña a la historia de la prostitución de las mujeres y que la mantiene todavía hoy en las profundidades de la jerarquía sexual (...) de la sociedad. Abstract: This article aims to analyze the reasons why prostitutes because of their sexual option have been criminalized by imposing highly coercive normative orders that censure severely their deviation. These normative orders -and their powerful discourses- explain the continuous and endless continuum of stigma, persecution, inferiority, social isolation or imprisonment that accompains the history of prostitution of women and that remain still today in the depths of the sexual hierarchy of society. (shrink)

In proposing this reflection about the relationship between dogmatic theology and Christian spiritual experience, we want to demonstrate in this article how a great 20 th century theologian, Hans Urs von Balthasar, invites the reader to enter into the reading and understanding of the historical and theological reasons that have guided some options and postures assumed, as well as to recognize the impacts caused both in the theology and in the spiritual experience and yet, more widely, in Christianity and its (...) mission. The path chosen for this study starts from one of his works, L’amour seul est digne de foi, and relies, then, in the impressive intellectual patrimony of the author, by researching in the same the transversality of the theme. We will be, in the present work, vigilant to the threat of disruptions, particularly analyze the conception and the possibility of the Christian spiritual experience by inquiring the Old Testament, the New Testament and the Holy Fathers. What is the hope delineated in this dialogue? It will be possible to infer partial conclusions from the route made. Further researches will be essential in order to reach the understanding of everything that is at stake in the search for intelligibility of the Theology and of the Christian experience itself. (shrink)

This chapter discusses the topics of trust and expertise from the perspective of political epistemology. In particular, it addresses four main questions: (§1) How should we characterise experts and their expertise? (§2) How can non-experts recognize a reliable expert? (§3) What does it take for non-experts to trust experts? (§4) What problems impede trust in experts?

In the ongoing pandemic, death statistics influence people’s feelings and government policy. But when does COVID-19 qualify as the cause of death? As philosophers of medicine interested in conceptual clarification, we address the question by analyzing the World Health Organization’s rules for the certification of death. We show that for COVID-19, WHO rules take into account both facts and values.

The mind is a powerful anticipatory device. It frequently makes predictions about the future, telling us not only how the world might or will be, but also how it should be - or better - how we would like it to be. This book explores anticipation-based emotions - the emotions associated with the interaction between 'what is' and 'what is not '.

Academic freedom has often been defended in a progressivist manner: without academic freedom, creativity would be in peril, and with it the advancement of knowledge, i.e. the epistemic progress in science. In this paper, I want to critically discuss the limits of such a progressivist defense of academic freedom, also known under the label ‘argument from truth.’ The critique is offered, however, with a constructive goal in mind, namely to offer an alternative account that connects creativity and academic freedom in (...) a way that goes beyond mere reference to epistemic progress and involves reference to the freedom to think independently as the freedom we mean when we point to creativity and when we point to academic freedom. The resulting causal independence account is not only epistemologically stronger than a progressivist account, it also allows to counter the curbing of academic freedom in the name of progress. The latter becomes key, for instance, when authoritarian political regimes limit or negate academic freedom with reference to an epistemic progress suitably defined for that regime. (shrink)

We discuss the 'problem of convergent knowledge', an argument presented by J. Schaffer in favour of contextualism about knowledge attributions, and against the idea that knowledge- wh can be simply reduced to knowledge of the proposition answering the question. Schaffer's argument centrally involves alternative questions of the form 'whether A or B'. We propose an analysis of these on which the problem of convergent knowledge does not arise. While alternative questions can contextually restrict the possibilities relevant for knowledge attributions, what (...) Schaffer's puzzle reveals is a pragmatic ambiguity in what 'knowing the answer' means: in his problematic cases, the subject knows only a partial answer to the question. This partial knowledge can be counted as adequate only on externalist grounds. (shrink)

This article proposes an account of knowing-who constructions within a generalisation of Hintikka’s quantified epistemic logic employing the notion of a conceptual cover Aloni PhD thesis [1]. The proposed logical system captures the inherent context-sensitivity of knowing-wh constructions Boër and Lycan, as well as expresses non-trivial cases of so-called concealed questions Heim. Assuming that quantifying into epistemic contexts and knowing-who are linked in the way Hintikka had proposed, the context dependence of the latter will translate into a context dependence of (...) de re attitude ascriptions and this will result in a ready account of a number of traditionally problematic cases including Quine’s well-known double vision puzzles Quine. (shrink)

Our evaluation of questions and knowledge attributions may vary relative to the way in which the relevant objects are identified. In the first part, the article proposes a theory that represents different methods of trans-world identification and is able to account for their impact on interpretation. In the second part, the same theory is used to account for the meaning of concealed questions. On the proposed account, the interpretation of a concealed question results from the application of a type-shifting operation (...) mapping an individual denoting expression into an identity question interpreted relative to a contextually selected identification method. (shrink)

This paper addresses whether the often-bemoaned loss of unity of knowledge about humans, which results from the disciplinary fragmentation of science, is something to be overcome. The fragmentation of being human rests on a couple of distinctions, such as the nature-culture divide. Since antiquity the distinction between nature (roughly, what we inherit biologically) and culture (roughly, what is acquired by social interaction) has been a commonplace in science and society. Recently, the nature/culture divide has come under attack in various ways, (...) in philosophy as well as in cultural anthropology. Regarding the latter, for instance, the divide was quintessential in its beginnings as an academic dis-cipline, when Alfred L. Kroeber, one of the first professional anthropologists in the US, rallied for (what I call) the right to ignore—in his case, human nature—by adopting a separationist epistemic stance. A separationist stance will be understood as an epistemic research heuristic that defends the right to ignore a specif-ic phenomenon (e.g., human nature) or a specific causal factor in an explanation typical for a disciplinary field. I will use Kroeber’s case as an example for making a general point against a bias towards integration (synthesis bias, as I call it) that is exemplified, for instance, by defenders of evolutionary psychology. I will claim that, in principle, a separationist stance is as good as an integrationist stance since both can be equally fruitful. With this argument from fruitful sepa-ration in place, not just the separationist stance but also the nature/culture di-vide can be defended against its critics. (shrink)

Aristocles of Messene is a first century AD Aristotelian philosopher who discusses the thought of ancient Greek philosophers, including Plato, Zeno, Pyrrho, and Epicurus, as well as Eleatic and Cyrenaic philosophies. His main contribution is his testimony on Pyrrhonism, and his political verve makes his On Philosophy an interesting and amusing read for specialists and non-specialists alike.

Maria Baghramian; XIV*—Why Conceptual Schemes?, Proceedings of the Aristotelian Society, Volume 98, Issue 1, 1 June 1998, Pages 287–306, https://doi.org/10.1111.

RESUMO O objetivo deste trabalho é indicar como a exploração estilística de Margaret Cavendish responde às particularidades do conceito de natureza dela, por exemplo, a tese de que a natureza é uma matéria viva, infinita, mutável e heterogênea. Primeiramente, mostrarei o modo pelo qual a autora está presente em seus escritos, como ela escreve de uma perspectiva de primeira pessoa sobre sua própria experiência e de quem ela é. Resumirei brevemente sua biografia e o contexto no qual ela praticou filosofia. (...) Dado que suas escolhas de estilo são bastante numerosas, apresentarei somente algumas poucas, entre as peculiaridades estilísticas dela. Em segundo lugar, desenvolverei uma visão geral do seu conceito de natureza, ao contrário do proposto pelas teorias mecanicistas de seu tempo. Esclarecerei que tal conceito é expresso adequadamente pela diversidade estilística à qual Cavendish se volta em suas investigações. ABSTRACT This paper aims at indicating how Margaret Cavendish's stylistic exploration answer to the particularities of her concept of nature, i.e. the thesis that nature is live, infinite, changing and heterogeneous matter. I will first show the way in which the author is present in her writings, as she writes from a first person perspective about her own experience and from who she is. I will briefly summarise her biography and the context in which she practiced philosophy. Given that her stylistic choices are quite numerous, I will only present a few of her stylistic particularities. Secondly, I will develop the general outline of her concept of nature, as opposed to the one proposed by the mechanistic theories of her time. I will make it clear that said concept is adequately expressed in the stylistic diversity to which Cavendish turns in her investigations. (shrink)

The effort to define the term “emotion” has a long history in the discipline of psychology. Izard’s survey (2010) canvassed prominent emotion theorists and researchers on their working definitions of emotion. The particular assumptions about emotion reported, as well as the conclusion that the term “emotion” lacks a consensus definition, both have historical precedent. In this commentary, I place Izard’s findings in this historical context and discuss the implications of his survey for the future of emotion research.

This work presents an analysis of the feeling of guilt and in particular of the cognitive defenses against it. It shows how the need to avoid or mitigate the feeling, with the suffering implied, affects the perception and judgment of oneself and others. It is in fact claimed that to copy with their guilt people try to alter the appraisal processes implied by the emotion. Once described the main cognitive components of the feeling of guilt, an analysis is offered of (...) the interventions of the cognitive defenses on such components, to alter the original appraisal processes underlying the feeling. (shrink)

Background: This study investigated the factors affecting the acceptability in France of abortions. Method: 80 study participants from Toulouse and 124 from Metz judged the acceptability of abortion in 64 vignettes composed of five factors: 1) the adolescent's age (15 or 17.5 years), 2) the adolescent's plans to continue schooling or not, 3) the fetus' age (1, 2, 3, or 4 months), 4) the adolescent's parents' agreement or not, and 5) the agreement or not of baby's father. Results: Three clusters (...) were noted: 1) abortion is never acceptable (8% of participants), 2) abortion is always acceptable (23%), and 3) acceptability of abortion depends on the circumstances (63%). In the majority cluster (3), all five factors had significant effects, but the fetus's age accounted for most of the variance (78%). Conclusion: Most subjects in this study judged, in accordance with French law, that the acceptability of induced abortion in minors depends on the circumstances and, in particular, on the fetus' age. (shrink)

It seems natural to think that there are aesthetic reasons for action and that an artist must be guided by such reasons as he or she begins work on the canvas or poem or symphony or marble. This latter supposition seems at odds, however, not only with classical inspiration theory but also with the views of one of the last century’s most important philosophers of art, R. G. Collingwood. We propose an account of acting for an aesthetic reason inspired by (...) G. E. M. Anscombe’s Intention, specifically by her concept of ‘practical knowledge’, which we believe can accommodate Collingwood’s reservations about the sort of knowledge of their ends, and of the means to those ends, which artists have as they engage in their creative activity. (shrink)

Background: Essential for the help relation, empathy is the ability to understand, share, and perceive the subjective experience of other human beings. Objective: The objective in this non-experimental, exploratory, and descriptive research was to verify, observe, and document empathy in nursing professionals. Research design: Non-experimental, exploratory, and descriptive research. Participants and research context: the study was conducted at two large hospitals, one public and the other private, across all shifts. The sample included 159 individuals. A questionnaire was used to identify (...) sociodemographic characteristics and the empathy inventory was applied. Ethical considerations: This study received approval from the Research Ethics Committee at the University of São Paulo at Ribeirão Preto College of Nursing, opinion 1348/2011, and authorization from the health institutions involved. Findings: The association tests demonstrated that professionals working in the night shift and in a work scale rotation scheme, older professionals, and professionals with longer professional experience are less empathetic. On the other hand, professionals working in the day shift and in a single shift are more empathetic. Other influential factors are the time on the job, education, and work shift. Conclusion: There is a lack of empathy studies in professional practice contexts, in human resource development programs, and throughout the professional education process. (shrink)

La profusa utilización del concepto de buen gobierno en los discursos políticos y mediáticos puede conducirnos a pensar que estamos ante una innovación conceptual del presente. Pero lo cierto es que se trata de un viejo concepto que hunde sus raíces en la teoría política clásica y se resiste a una definición clara y precisa. El artículo pretende reflexionar sobre los principales cambios experimentados por el buen gobierno y su metamorfosis en gobernanza, analizándolo como una narrativa de transformación conceptual, en (...) la que se ha pasado de una lógica normativa a una lógica tecnocrática. (shrink)

Many philosophical counselors seem to be counselors who use or point to phil­osophical texts or use abstract indeed logical or rational methods when working with a client. I want to introduce the idea of a counseling philosopher, who uses the client’s own concrete experiences as the basis for philosophizing with the client about the nature of the client’s dilemma - using ‘the between’ (Buber) as that special creative space where one em­ploys the art of philosophizing to the unique situation. Otherwise, (...) the particularity of that client gets subsumed under theory or methods, much like what has happened in psychology and which gave rise to Achenbach’s criticisms of psychology/psychiatry. The dialogical of which Buber and Friedman speak is the give and take between client and counseling philosopher of understanding and expanding perceptions confirmed through the actual relationship. Philosophy as an art (and not a method) helps us restore the trust Buber talks about which allows us to engage the world directly and not through categories of thought grounded in psychological or philosophical texts and theories. (shrink)

In this paper I will discuss certain aspects of Leibniz's theory and practice of 'soft reasoning' as exemplified by his defence of two central mysteries of the Christian revelation: the Trinity and the Incarnation. By theory and practice of 'soft' or 'broad' reasoning, I mean the development of rational strategies which can successefully be applied to the many areas of human understanding which escape strict demonstration, that is, the 'hard' or 'narrow' reasoning typical of mathematical argumentation. These strategies disclose an (...) 'other' reason, i.e. a complementary set of arguments and methods developed by Leibniz in order to deal with crucial issues such as the 'weighting' of probabilities and truths of fact. I will argue that one of the most compelling examples of the importance and fertility of Leibniz's 'other' reason is provided by his solution to the problems posed by the unique epistemological status of theological mysteries. (shrink)

Name der Zeitschrift: Der Islam Jahrgang: 94 Heft: 2 Seiten: 322-335.

Este artigo, apoiado na perspectiva teórica sócio-histórico-cultural, discute a atividade na qual sujeitos se envolvem como constitutiva dos papeis sociais que exercem. Objetiva desencadear discussão acerca da dinâmica discursiva em contextos de formação crítico-colaborativa de professores, focalizando os discursos de autoridade e internamente persuasivo (BAKHTIN, 2010) e sua coocorrência nas situações de negociação de significados. Tal distinção constitui-se relevante por permitir compreender diferentes enunciados argumentativos ou não, proferidos por educadores em formação, que se proximam ou se distanciam daqueles proferidos por (...) seus formadores ou por vozes teóricas isoladas da prática, indicando possibilidades de criação ou diminuição da expansão dialógica. A partir da ênfase no discurso internamente persuasivo, procura-se destacar o papel crítico-colaborativo da argumentação na formação de educadores. Exemplos selecionados de um corpus de pesquisa coletado em escola pública de São Paulo subsidiará a discussão, por sua vez, apoiada em Bakhtin (2010) e Vygotsky (1998; 2001). (shrink)

Una investigación que se centra en torno a la fuerza de la imaginación con el propósito básico de alcanzar una aproximación desde perspectivas plurales, diversas al poder humano de imaginar. La imaginación es una función compleja que exige ser abordada desde diversos ángulos, cada uno de los cuales arrojará una luz parcial sobre determinados aspectos y facetas pero no sobre otros, no sobre todos.

Abortion has become such an indispensable part of contemporary experience that even Christians sometimes find it difficult to oppose. Since taking the life in utero has ceased to be regarded as a grave sin and is not always recognized as an unmitigated evil, those who wish to remain faithful to the Word of God struggle to find ways of speaking against killing of the unborn. Some of them, like Erika Bachiochi, seek to beat modern culture at its own game, by (...) representing Catholic teaching on human sexuality as a “right kind” of feminism. However, in her appeal to secular rationality, foregoing the metaphysical commitments of faith and replacing them with the consequentialist reasoning and data from scientific research, she thereby renders her alternative unviable and un-Christian. In response to this failure, I would like to present some Orthodox Christian considerations pointing toward a more wholesome and consistent way forward. (shrink)

Using Leventhal’s (Social exchange: Advances in theory and research, Plenum Press, New York, 1980 ) rules of procedural justice as well as deontic justice (Folger in Research in social issues in management, Information Age, Greenwich, CT, 2001 ), we examine how personal value for diversity moderates the negative relationship between perceived discrimination against minorities (i.e., racial minorities and females) at work and the perceived procedural justice of minorities’ treatment by the organization. Through a field survey of 190 employees, we found (...) that observers high in personal value for diversity have stronger negative reactions to the mistreatment of women and racial minorities than observers low in personal value for diversity. These findings support and extend the deontic justice perspective because those who personally value diversity had the strongest negative reactions toward the discriminatory treatment of minorities. (shrink)

RESUMEN El concepto heterotopía, definido por Michel Foucault como espacio otro, es retomado en este artículo, desde un enfoque crítico, para analizar los procesos de construcción, gestión y puesta en marcha del Museo Itinerante de la Memoria y la Identidad de Los Montes de María, El Mochuelo. Bajo la premisa de que el desarrollo de los procesos de memorialización debe atenderse más allá del cumplimiento normativo por parte del Estado, puesto que estas prácticas de memoria territoriales en El Mochuelo subvierten (...) el estatismo y la homogeneidad con los cuales se instauran las verdades oficiales. ABSTRACT Heterotopia concept, defined by Michel Foucault as another space, is taken up in this article to analyze the processes of construction, management, and implementation of the Museo Itinerante de la Memoria y la Identidad de Los Montes de María, El Mochuelo (Itinerant Museum of Memory and Identity of Los Montes de María, El Mochuelo). Under the premise that the development of memorialization processes must be addressed beyond regulatory compliance by the State since these territorial memory practices in El Mochuelo subvert the statism and homogeneity with which official truths are established. (shrink)

L’adjectif eoikos apparaît dans trois passages cruciaux de la pensée grecque (Xénophane, fr. B35 ; Parménide, fr. B8, 60 ; Platon, Timée, 29b3-c3), caractérisant une certaine « ressemblance » à la vérité qui se veut constitutive du discours du savant. En fait, le long de cet examen on découvre que les trois usages du terme ne peuvent pas être disposés le long d’une ligne continue, vu la difficulté de comprendre à quelle notion de vérité, sous quel point de vue, et (...) avec quel degré d’évidence, ce discours se veut « ressemblant » selon l’occasion. Dans le cas de Parménide, cet aspect passe même au second plan, puisqu’on assiste à la prédominance d’une autre connotation qui accompagne le terme eoikos à partir de l’usage homérique, à savoir celle de la « convenance » à un contexte communicatif. L’article cherche dans l’ensemble à éclairer les déplacements que subit la logique de la similitude (et des procédés analogiques qui s’y greffent) en passant par des cadres ontologiques et épistémologiques aussi différents que le sont ceux de Xénophane, Parménide et Platon. (shrink)

According to Chandra Mohanty, there is no apolitical academy; academic and scholarly practices are in themselves political, insofar as they are inscribed in power and validation relations, which answer to and have effects upon the patriarchal, colonial, and capitalist structures to which they belong. In the case of philosophical writing, this means that the forms that regulate writing, that is, what determines how one must write in different contexts, are expressive of the power structures within philosophical academia. These power structures (...) are upheld through time because of, among many other factors, the rendering invisible of the diversity of places of enunciation belonging to those who write and think in philosophy, and of the universalization of the privileges associated with said places of enunciation. In this article, I propose a way of writing letters that appeals to grammatical persons and their relation to the authors of the texts. Through this writing practice it is possible to make explicit the places of enunciation from which we write philosophy. This enables, first, making visible the privileges and oppressions of those writing philosophy; and second, generating small spaces of resistance and transformation of the oppressive power relations within the philosophical academy. (shrink)