Polypeptide growth factors (mitogens) which stimulate proliferation of fibroblasts and epithelial cells also rapidly activate transmembrane ion transport systems. The mitogen‐induced Na+ influx is due to the activation of a Na+/H+ antiport. Recent methodological developments allow, for the first time, precise measurements of the factors that control activation of the Na+/H+ antiport by these agents, and provide the tools needed to assess the physiological significance of this exchange mechanism.

Logic arguably plays a role in the normativity of reasoning. In particular, there are plausible norms of belief/disbelief whose antecedents are constituted by claims about what follows from what. But is logic also relevant to the normativity of agnostic attitudes? The question here is whether logical entailment also puts constraints on what kinds of things one can suspend judgment about. In this paper I address that question and I give a positive answer to it. In particular, I advance two logical (...) norms of agnosticism, where the first one allows us to assess situations in which the subject is agnostic about the conclusion of a valid argument and the second one allows us to assess situations in which the subject is agnostic about one of the premises of a valid argument. (shrink)

How does rationality bind the agnostic, that is, the one who suspends judgment about whether a given proposition is true? In this paper I explore two alternative ways of establishing what the rational requirements of agnosticism are: the Lockean–Bayesian framework and the doxastic logic framework. Each of these proposals faces strong objections. Fortunately, however, there is a rich kernel of requirements of agnosticism that are vindicated by both of them. One can then endorse the requirements that belong to that kernel (...) without thereby committing oneself to the problematic implications that stem from either of the aforementioned proposals. (shrink)

It is possible to find in Machiavelli an expression of the original consent to explain the origin of the political communities. This paper investigates this hypothesis in the approach of the roman political thought. With Lucretius and Cicero, it is clear the terms of the pact, covenant, consensus, and the primitivism of the difference between man and beasts, the fear and the common safety to founder the political community under the leadership of one man. The paper also debates the Aristotelian (...) premises of the political nature of man and explores some examples of the Machiavellian time, that aims to confirms the existence of the language of the Aristotelianism within the original consent. It concludes that Machiavelli does not have a substantial theory to explain the origins of the political community, because politics and its study requires the research of the cities in the historical mean. This contractual language in accordance with that Aristotelian is used as a rhetoric strategy in the beginning of the Discourses. (shrink)

Nowadays, batteries play an important role in a lot of different applications like energy storage, electro-mobility, consumer electronic and so on. All the battery types have a common factor that is their complexity, independently of its nature. Usually, the batteries have an electrochemical nature. Several different test are accomplished to check the batteries performance, and commonly, it is predictable how they work depending of their technology. The present research describes the hybrid intelligent system created to accomplish fault detection over a (...) Lithium Iron Phosphate—LiFePO4 power cell type, commonly used in electro-mobility applications. The approach is based on the cell temperatures behaviour for voltage and current specific values. Taken into account the operating range of a real system based on a LiFePO4 cell, a large set of points of operation have been used to achieve the dataset. The different behaviour zones have been obtained by clustering as a first step. Then, different regression techniques have been used over each cluster. Polynomial regression, artificial neural networks and support vector regression were the combined techniques to develop the hybrid intelligent model proposed. The intelligent system gives very good results over the operating range, detecting all the faults tested during the validation. (shrink)

Adorno's aesthetic is organized in fields of force, under which orbiting constellations of categories which reflect the truth of the managed world in the era of late capitalism. Understand the nuances of this aesthetic is preparing to reinterpret the world, so as to achieve the things forgotten by the concept. In this sense, the aesthetic becomes a way of reconnecting the human sciences with the reality, from the recovery of sensitivity troubled by the dominance of instrumental reason.

The paper contains a detailed discussion of the concepts of reflection and expressivity and attempts to exhibit their central role in the Herderian philosophy of language as well as their character as a leading thread throughout Herder’s theories of culture and history. Herder’s idea of a wide ..

Este artículo examina la jurisprudencia constitucional relativa a la legitimación en la Jurisdicción de lo Contencioso-Administrativa, en general, y sobre la legitimación de las asociaciones, particularmente, haciendo hincapié en la importancia de esta cuestión para la protección de los derechos constitucionales y la protección de los intereses colectivos. El autor, recordando que la legitimación activa plazo es la capacidad de una parte para demostrar a la corte que existe una vinculación suficiente con el objeto procesal a fin de justificar su (...) participación en el caso (algo que perder, algo para ganar), las notas el papel del Tribunal Constitucional español en subrayar que la legitimación activa debe interpretarse en sentido amplio, en contraste con otra sentencia más restrictivas en la jurisprudencia administrativa. La interpretación amplia de la legitimidad está estrechamente vinculada no solo con los derechos de acceso a la justicia (especialmente intensa cuando se determina la imposibilidad de obtener una respuesta judicial inicial) y el derecho constitucional a la tutela judicial efectiva, sino también para controlar judicial efectiva y la acción firme de la Administración con arreglo a Derecho por los tribunales, lo que permite combatir las prácticas corruptas y los casos de abuso del poder público. En resumen, la interpretación amplia de legitimación es la mejor solución contra los conceptos anticuados que impiden el acceso a la justicia. (shrink)

The article explores the moral conflict between individual animal rights and the value of species conservation, using the culling of kangaroos to save earless dragons in Australia as a case study. The author argues that species do not possess nonderivative final value and thus cannot justify the infringement of individual rights. While recognizing the instrumental and contributory value of species, the paper rejects philosophical arguments that claim species have nonderivative value, such as the replication argument and the last person argument. (...) The author concludes that while there are important conservation duties, they should not violate individual rights, as exemplified by the kangaroo culling practice, which must be abolished. (shrink)

El artículo indaga y compara diferentes posturas que se tiene sobre la informalidad comercial en Latinoamérica, en donde se realiza una revisión detallada y analítica de este fenómeno; que se define como el conjunto de actividades comerciales no reguladas, que en estos países desborda la institucionalidad, generando un deterioro de la estructura social, económica, política e inclusive humana. Estas dificultades tienen su origen en una serie de situaciones como la pobreza, el desempleo, el desplazamiento, la migración, el analfabetismo, entre otros; (...) las cuales son importantes conocer y analizar a fin de generar soluciones reales a estas profundas dificultades. (shrink)

Tomando como punto de partida el artículo 27.7 de la Constitución Española, que reconoce expresamente que "los profesores, los padres y, en su caso, los alumnos intervendrán en el control y gestión de todos los Centros sostenidos por la Administración con fondos públicos, en los términos que la ley establezca", nuestro sistema jurídico educativo ha venido estableciendo un marco de actuación de los conocidos Consejos Escolares de los Centros, marco que lejos de haber permanecido inalterado desde la Ley Orgánica reguladora (...) del Derecho a la Educación (19885), he evolucionado llamativamente con el transcurso de los años, a través de las sucesivas Leyes orgánicas: Ley Orgánica de Participación, Evaluación y Gobierno de los Centros (LOPEG, 1995), Ley Orgánica de Calidad de la Educación (LOCE, 2002) y Ley Orgánica de Educación (LOE, 2006. (shrink)

Suprastate policy formation in such bodies as the WTO remains fundamentally exclusive of individuals within states. This article critiques the "don't kill the goose" arguments commonly offered in defense of such exclusions.

O problema da felicidade é recorrente nos tratados sobre Ética da Antiguidade. Os medievais defrontam-se com eles ao escreverem seus próprios textos. Neste trabalho procura-se analisar a forma como Tomás de Aquino e Boécio de Dácia, ao produzirem textos não teológicos, incorporam a seus tratados as obras antigas, principalmente de Aristóteles e Severino Boécio.

El cultivo de la filosofía, particularmente el de la metafísica, constituye el fin último del hombre y cuyo acto tiene por objeto la contemplación de Dios ut auctornaturae. Ahora bien, la Revelación cristiana introduce dos factores determinantes que modificaron la condición pura de nuestra naturaleza: la elevación al orden sobrenatural y la intromisión del pecado original. De allí que, por un lado, el fin último del hombre consistirá en la visión sobrenatural de Dios ut auctor gratiae y, por otro, la (...) necesidad de la gracia sanadora y elevadora para llegar a esa visión. No obstante, Santiago Ramírez siguiendo a Santo Tomás de Aquino, explicará que el hombre actual –es decir, caído por el pecado– es impotente incluso para alcanzar su fin connatural sin la ayuda de la gracia. (shrink)

El presente artículo recupera los argumentos de Agamben respecto del infundamento del derecho, la violencia que le es intrínseca y la centralidad de la ficción en los dos primeros volúmenes de Homo sacer, _El poder soberano y la nuda vida_, _Estado de excepción_. A su vez, estudia la potencia diagnóstica de la apropiación que hace Agamben de las tesis de Schmitt, así como la crítica que despliega a sus límites teóricos desde Benjamin.

The present paper intends to place “Lo que queda de Auschwitz” in the Homo Sacer’s proyect started by Giorgio Agamben in 1995. In order to do so, we must point out, in the first place, the need of understanding this proyect as a political ontology, then the relation between this proyect and the philosophy of language of his youth, along with its ethical claims, and, finally, we must identify some of his fundamental moves, as the formation of ontological categories created (...) from historical figures which are able to show the “arcanum imperii” of the political system to which they belong. As a result, the paper shows the metaphysical foundation of the analysis of the subject carried out in “Lo que queda de Auschwitz”, and the way it affects the author’s ideas on ethics, leading to a open way to critics and posible reformulations. (shrink)

In this paper I attempt at drawing a philosophical picture about Cicero's ideas on after death survival. In spite of the fact that this issue has not been paid much attention in contemporary discussion, it deserves consideration because of its great humanistic value.

Este artículo reseña: Oscar PÉREZ DE LA FUENTE, Odio, minorías y libertad de expresión.

El pensamiento español contemporáneo.--España ante la idea sociológica del Estado.--Supervivencias de la Iberia primitiva en la España contemporánea.

This paper defends the view that a correct analysis of knowledge must take empirical data into consideration. The data here provided is from experimental psychology, namely from phenomena involving unconscious cognition.

Este ensayo aborda una interpretación de la violencia, la criminalidad y la corrupción en la sociedad, a partir del estudio de un cúmulo de fuentes de diversa índole, y del análisis crítico de las interpretaciones vigentes. Por ello, se discuten, con cierto detalle, los efectos perniciosos del predominio del platonismo en la interpretación de dichas fuentes, y se propone, de la mano de Nietzsche y del pensamiento evolucionista, un abordaje del problema, que, apoyado en la perspectiva del platonismo invertido planteado (...) por el filósofo, concibe la sociedad como un ecosistema, esto es, un sistema vivo, donde cada individuo debe enfrentar el reto de sobrevivir, arreglándoselas para obtener recursos que aseguren su existencia. Así, hemos identificado diferentes modos de supervivencia y los hemos clasificado en tres categorías: 1) generadores (creadores-productores); 2) saqueadores (parásitos, predadores y oportunistas) y, 3) simbiontes (mutualistas y leoninos). (shrink)